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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 邵耀華(Yio-Wha Shau) | |
dc.contributor.author | Ming-Chien Yu | en |
dc.contributor.author | 游明諫 | zh_TW |
dc.date.accessioned | 2021-06-15T00:37:00Z | - |
dc.date.available | 2011-12-24 | |
dc.date.copyright | 2008-12-24 | |
dc.date.issued | 2008 | |
dc.date.submitted | 2008-12-03 | |
dc.identifier.citation | [1] 衛生統計資訊網 http://www.doh.gov.tw/statistic/
[2] Celle G, Savarino V, Picciotto A, Magnolia MR, Scalabrini P, Dodero M. Is hepatic ultrasonography a valid alternative tool to liver biopsy? Report on 507 cases studied with both techniques. Dig Dis Sci 1988;33:467–71. [3] Gaiani S, Gramantieri L, Venturoli N, Piscaglia F, Siringo S, D’Errico A, et al. What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy. J Hepatol 1997;27:979–85. [4] Tu‥ney D, Aribal ME, Ertem D, Kotilogˇlu E, Pehlivanogˇlu E. Diagnosis of liver cirrhosis in children based on colour Doppler ultrasonography with histopathological correlation. Pediatr Radiol 1998;28:859–64. [5] Khan KN, Yamasaki M, Yamasaki K, Inoue O, Yatsuhashi H, Koga M, et al. Proposed abdominal sonographic staging to predict severity of liver diseases: analysis with peritoneoscopy and histology. Dig Dis Sci 2000;45:554–64. [6] Nicolau C, Bianchi L, Vilana R. Gray-scale ultrasound in hepatic cirrhosis and chronic hepatitis: diagnosis, screening, and intervention. Seminars in US, CT and MRI 2002;23:3–18. [7] Nishiura et al. Ultrasound evaluation of the fibrosis stage in chronic liver disease by the simultaneous use of low and high frequency probes. The British Journal of Radiology, 78 (2005), 189–197 [8] Yang PM et al:Ultrasonography in the Diagnosis of Benign DiffuseParenchymal Liver Diseases: A Prospective Study. J Formosan Med Assoc 1988; 87: 966 [9] N.E. Huang et al. (1998), “The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis.” Proceedings of the Royal Society of London Series a-Mathematical Physical and Engineering Sciences, 1998. 454(1971): p. 903-995. [10] C. M. Wu, Y. C. Chen, and K. S. Hsieh, 'Texture features for classification of ultrasonic liver images,' IEEE Trans. Med. Imaging 11(2):141-152 (1992). [11] Y. N. Sun, M. H. Horng, X. Z. Lid, and J. Y. Wang, 'Ultrasonic image analysis for liver diagnosis: A noninvasive alternative to determine liver disease,' IEEE Engineering in Medicine and Biology 15(6):93-101(1996). [12] Y. M. Kadah, A. A. Farag, J. M. Zurada, A. M. Badawi, and A. M. Youssef, “Classification algorithms for quantitative tissue characterization of diffuse liver disease from ultrasound images,” IEEE Trans. Med. Imaging 15(4):466–478 (1996). [13] A. Mojsilovic, M. Popovic, S. Markovic, and M. Krstic, 'Characterization of visually similar diffuse diseases from B-scan liver images using nonseparable wavelet transform,' IEEE Trans. Med. Imaging 17(4): 541-549 (1998). [14] K. Ogawa, M. Fukushima, K. Kubota, and N. Hisa, “Computer-aided diagnostic system for diffuse liver diseases with ultrasonography by neural networks,” IEEE Trans. Nucl. Sci. 45(6):3069–3074 (1998). [15] M. H. Horng, Y. N. Sun, and X. Z. Lin, “Texture feature coding method for classification of liver sonography,” Comput. Med. Imaging Graph. 26: 33–42 (2002). [16] W. C. Yeh, S. W. Huang, and P. C. Li, 'Liver fibrosis grade classification with B-mode ultrasound,' Ultrasound Med. Biol. 29(9): 1229-35 (2003). [17] G. T. Cao, P. F. Shi, and B. Hu, 'Ultrasonic Liver Discrimination Using 2-D Phase Congruency,' IEEE Trans. Biomed. Eng. 53(10): OCTOBER (2006). [18] Colli, A., M. Cocciolo, et al. 'Abnormalities of Doppler waveform of the hepatic veins in patients with chronic liver disease: correlation with histologic findings.' AJR Am. J. Roentgenol 162(4): 833-837 (1994). [19] Bolondi, L., S. Li Bassi, et al. 'Liver cirrhosis: changes of Doppler waveform of hepatic veins.' Radiology 178(2): 513-516 (1991). [20] Barakat, M. (2004). 'Non-pulsatile hepatic and portal vein waveforms in patients with liver cirrhosis: concordant and discordant relationships.' Br J Radiol 77(919): 547-50. [21] Aube, C., B. Winkfield, et al. (2004). 'New Doppler ultrasound signs improve the non-invasive diagnosis of cirrhosis or severe liver fibrosis.' Eur J Gastroenterol Hepatol 16(8): 743-51. [22] Kawasaki, T., T. Itani, et al. (1999). 'Portal venous volume flow: in vivo measurement by time-domain color-velocity imaging.' Ultrasound Med Biol 25(6): 915-21. [23] Piscaglia, F., S. Gaiani, et al. (1997). 'Intra- and extrahepatic arterial resistances in chronic hepatitis and liver cirrhosis.' Ultrasound Med Biol 23(5): 675-82. [24] Albrecht, T., M. J. Blomley, et al. (1999). 'Non-invasive diagnosis of hepatic cirrhosis by transit-time analysis of an ultrasound contrast agent.' Lancet 353(9164): 1579-83. [25] Zheng, R. Q., B. Zhang, et al. (2005). 'Hemodynamic and morphologic changes of peripheral hepatic vasculature in cirrhotic liver disease: a preliminary study using contrast-enhanced coded phase inversion harmonic ultrasonography.' World J Gastroenterol 11(40): 6348-53. [26] Hirota, M., T. Kaneko, et al. (2005). 'Intrahepatic circulatory time analysis of an ultrasound contrast agent in liver cirrhosis.' Liver Int 25(2): 337-42. Giuseppetti, G. M., G. Argalia, et al. (2004). 'Liver cirrhosis: evaluation of haemodynamic changes using an ultrasound contrast agent.' Eur J Radiol 51(1): 27-33. [27] Giuseppetti, G. M., G. Argalia, et al. (2004). 'Liver cirrhosis: evaluation of haemodynamic changes using an ultrasound contrast agent.' Eur J Radiol 51(1): 27-33. [28] Sandrin, L., B. Fourquet, et al. (2003). 'Transient elastography: a new noninvasive method for assessment of hepatic fibrosis.' Ultrasound Med Biol 29(12): 1705-13. [29] KHALEQUE NEWAZ KHAN (1) ; YAMASAKI M. (1) et al. (2000). “Proposed Abdominal Sonographic Staging to Predict Severity of Liver Diseases : Analysis with peritoneoscopy and histology.” Digestive Diseases and Sciences 45(3): 554–564 | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/41910 | - |
dc.description.abstract | 慢性肝病患者的肝組織纖維化程度對於決定患者治療的方式以及評估治療之後的效果是很重要的因子。雖然肝臟穿刺檢驗是評估肝纖維化程度以及肝病成因的黃金標準,但肝穿刺檢驗仍是侵入式的檢驗方法且伴隨有術後併發症的風險、患者的不舒適以及較高的成本等缺點。此外肝穿刺檢驗會因為不合適的組織取樣而會導致假陰性的診斷結果,況且早期肝臟纖維化在穿刺檢查仍有很大的不確定性。因此發展一套簡單、可靠且具有非侵入性的方式來評估患者肝纖維化程度在臨床上是有其必要性。超音波是非常好的軟組織檢測工具,尤其是深部的肝臟。不過超音波影像易受到的干擾與訊號衰減等影響。本研究提出一個基於經驗模態分解法的紋理分析演算法用來從超音波影像中區分患者有無肝組織硬化。16位肝硬化的患者與10位無肝硬化的受試者被用來評估所該演算法的效能。結果顯示第三層經驗模態影像的Normalized Sum Entropy在診斷有無肝硬化上有顯著的統計差異 (p value < 0.0001, AUC = 0.774~0.854) | zh_TW |
dc.description.abstract | The liver fibrosis stage in patients with viral or non-viral chronic hepatitis is a pivotal factor regarding both the therapeutic options and for predicting the prognosis. Although percutaneous liver biopsy is the gold standard for diagnosing the liver fibrosis stage and predicting the outcome of the diseases, it is still an invasive procedure and associated with a risk of complications, patient discomfort and a high cost. In addition, liver biopsy examinations may lead to false negative results due to inadequate liver tissue sampling. More over, early hepatic fibrosis always exist problems. Therefore, there is an increasing need to develop a simple, reliable and non-invasive method in order to assess the liver fibrosis stage.Ultrasonography is a suitable tool for soft tissue, especially in deeper liver. However, the ultrasonography is often mixed with unwanted reflection and ambiguous attenuation. In this study, We present a texture analysis algorithm based on empirical mode decomposition for differential diagnosis of cirrhotic and noncirrhotic livers from ultrasonography. Patients with cirrhotic liver (n=16) and subjects with noncirrhotic livers (n=10) were studied. Normalized sum entropy of 3rd intrinsic mode image is statistical significant (p<0.0001, Az = 0.774~0.854) in differentiating the noncirrhotic liver and the cirrhotic liver. | en |
dc.description.provenance | Made available in DSpace on 2021-06-15T00:37:00Z (GMT). No. of bitstreams: 1 ntu-97-R95543018-1.pdf: 2940372 bytes, checksum: aa99a7d6f51bcd9cc745cc79fcdc664c (MD5) Previous issue date: 2008 | en |
dc.description.tableofcontents | 中文摘要..............................................I
英文摘要.............................................II 內文目..............................................III 圖目錄................................................V 表目錄.............................................VIII 第一章 序論..........................................1 1-1 前言...........................................1 1-2 研究動機與目的.................................2 1-3 文獻回顧.......................................6 第二章 研究原理.....................................11 2-1 超音波成像原理................................11 2-2 肝臟生理學....................................13 2-3 經驗模態分解..................................17 2-4 灰階共同發生矩陣..............................23 第三章 實驗流程與結果...............................31 3-1 受試者資料....................................31 3-2 ROI選取原則...................................32 3-3 紋理特徵擷取..................................33 3-4 實驗結果......................................34 3-5 結果討論......................................47 第四章 結論.........................................49 參考文獻.............................................52 | |
dc.language.iso | zh-TW | |
dc.title | 經驗模態分解法於肝硬化超音波影像分析 | zh_TW |
dc.title | Ultrasonography Analysis of Liver Cirrhosis: Using Empirical Mode Decomposition | en |
dc.type | Thesis | |
dc.date.schoolyear | 97-1 | |
dc.description.degree | 碩士 | |
dc.contributor.coadvisor | 李宣書(Hsuan-Shu Lee) | |
dc.contributor.oralexamcommittee | 王崇禮(Chung-Li Wang),包舜華(Sun-Hua Pao) | |
dc.subject.keyword | 肝硬化,超音波影像,經驗模態分解, | zh_TW |
dc.subject.keyword | cirrhosis,ultrasonography,empirical mode decomposition, | en |
dc.relation.page | 55 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2008-12-03 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 應用力學研究所 | zh_TW |
顯示於系所單位: | 應用力學研究所 |
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