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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/40394完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 林文澧 | |
| dc.contributor.author | Che-Yu Lin | en |
| dc.contributor.author | 林哲宇 | zh_TW |
| dc.date.accessioned | 2021-06-14T16:46:30Z | - |
| dc.date.available | 2008-08-04 | |
| dc.date.copyright | 2008-08-04 | |
| dc.date.issued | 2008 | |
| dc.date.submitted | 2008-07-31 | |
| dc.identifier.citation | [1] W.C. Dewey, S.A. Sapareto, D.A. Betten, “Hyperthermia radiosensitization of synchronous Chinese hamster cells: Relationship between lethality and chromosomal aberrations”, Radial. Res., Vol.76, pp. 48-59, 1978
[2] J.E. Kennedy, “High-intensity focused ultrasound in the treatment of solid tumours”, Nature Reviews Cancer, Vol.5, pp. 321-327, 2005 [3] S.T. Joseph, L. A. Frizzell, Narendra Sanghvi, Shih-jeh Wu, Ralf Seip Jeffrey T. Kouzmanoff, “Ultrasound phased arrays for prostate treatment“, J. Acoust. Soc. Am. 109 (6), pp. 3055-3064, June 2001 [4] L. Curiel, F. Chavrier, R. Souchon, A. Birer, Jean Y. Chapelon, “1.5-D high intensity focused ultrasound array for non-invasiv non-invasive prostate cancer surgery”, IEEE Transactions on ultrasonics, ferroelectrics, and frequency control, vol. 49, No. 2, February 2002 [5] David T. BlackStock, “Fundamentals of physical acoustics”, John Wiley & Sons Inc., 2000 [6] Lawrence E. Kinsler, Austin R. Frey, Alan B. Coppens, James V. Sanders, “Fundamentals of acoustics”, New York: Wiley, Third Edition, 1980 [7] D.R. Daum, N.B. Smith, R. King, K. Hynynen, “In vivo demonstration of noninvasive thermal surgery of the liver and kidney using an ultrasonic phased array”, Ultrasound Med. Biol., Vol.25, pp.1087-98, 1999 [8] Xiaobing Fan, Kullervo Hynynen, “The effects of curved tissue layers on the power deposition patterns of therapeutic ultrasound beams”, Medical Physics, Volume 21, Issue 1, pp.25-34, January 1994 [9] Hao-Li Liu, H Chang, W-S Chen, T-C Shih, J-K Hsiao, and W-L Lin, “Feasibility of transrib focused ultrasound thermal ablation for liver tumors using a spherically curved 2D array: a numerical study,” Medical Physics, Vol.34, No. 9, pp.3436-3448, 2007 [10] Hao-Li Liu, Nathan McDannold, and K. Hynynen, “Focal beam distortion and treatment planning in abdominal focused ultrasound surgery,” Medical Physics, Vol. 32, pp.1270-1280, 2005 [11] Kirk K. Shung and Michael Zipparo, “Ultrasonics Transducers and Arrays”, Engineering mMedicine and biology, pp.20-30, November/December, 1996 [12] L.E. Spence, A.J. Insel, S.H. Friedberg, “Elementary linear algebra: a matrix approach”, Pearson Education Taiwan Ltd., 2004 [13] Emad S. Ebbini, Charles A. Cain, “Multiple focus ultrasound phased-array pattern synthesis : optimal driving – signal distributions for hyperthermia”, IEEE Transactions on ultrasonics,ferroelectrics, and frequency control, Vol.36, NO. 5. September, pp.540-548, 1989 [14] 楊順聰編著, 臨床高等醫療儀器系統-原理與應用, 藝軒圖書出版社, 1988 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/40394 | - |
| dc.description.abstract | This study is to design a novel curved cylindrical ultrasound phased array for liver tumor therapy in ultrasound hyperthermia, and we attempt to track and treat the liver tumor by controlling the focus in 3-dimension.The goal of the study is to design the geometric configuration of the phased array, the focus-steering ability of the phase array, the thermal effect by the phased array and its application to liver tumor therapy.
We showed the ability of steering the focus of the curved cylindrical phased array is good in 2-dimension in a finite range. The sound intensity level, thermal effects and half-power beamwidth is suitable for liver tumor therapy. When compared with the cylindrical phased array, the curved cylindrical phased array is better in its sound intensity and the total effective power in the field. We also proved the feasibility of using pseudo-inverse method for focus-steering simulating in multi-layered environment. The first chapter is to introduce the ultrasound hyperthermia and its difficulties in treating the liver. The second chapter is to discuss the basic theorems and physical meaning of the acoustics and the ultrasound hyperthermia. The third chapter is to show the results for the curved cylindrical phased array simulation, including the focus-steering ability, the pattern of the natural focus, the thermal effects, simulation results in multi-layer environment, and the comparison between the curved cylindrical phased array and the cylindrical phased array. The last chapter is to sum up and discuss the results of the study. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-14T16:46:30Z (GMT). No. of bitstreams: 1 ntu-97-R95548006-1.pdf: 3412335 bytes, checksum: e26699577a523284511771a985d17e37 (MD5) Previous issue date: 2008 | en |
| dc.description.tableofcontents | 口試委員審定書............................................I
致謝.....................................................II 摘要....................................................III Abstract.................................................IV 目錄......................................................V 圖目錄...................................................VI 表圖錄..................................................VII 第一章 緒論...............................................1 1.1 肝臟治療簡介.....................................1 1.2 超音波熱治療簡介.................................3 1.3 考慮肝臟運動的超音波熱治療.......................5 1.4 研究動機與目標...................................6 第二章 理論分析與模擬方法.................................8 第一部份 模擬方法.........................................8 2.1 模擬方法..............................................8 第二部份 聲學理論.........................................9 2.2 聲波簡介..............................................9 2.3 線性波動方程式與平面波理論...........................11 2.4 聲波於介質中的能量效應以及衰減和吸收.................14 2.5 聲波源於波場造成的效應...............................17 2.6 聲波在介質界面上的效應...............................20 2.7 聲波行經多層介質的壓力計算...........................23 第三部份 超音波熱治療理論................................28 2.8 超音波換能器簡介.....................................28 2.9 聚焦型超音波換能器的聚焦點調變方式...................29 2.10 相位陣列系統的聚焦點調變式..........................31 2.11溫度與熱劑量分析.....................................36 第三章 曲面圓柱型相位陣列的設計與模擬結果................38 3.1 曲面圓柱型相位陣列的幾何結構說明.....................38 3.2 曲面圓柱型相位陣列的規格設計.........................39 3.2.1 設計時的模擬環境.................................39 3.2.2 元素數目規劃.....................................40 3.2.3 尺寸設定.........................................41 3.2.4 曲率半徑設定與最終設計規格.......................42 3.3 曲面圓柱型相位陣列的天然聚焦點型態...................50 3.4 曲面圓柱型相位陣列的三維聚焦點調變能力...............55 3.5 曲面圓柱型相位陣列的熱效應...........................64 3.6 曲面圓柱型與圓柱型相位陣列的比較.....................67 3.7 使用擬反矩陣理論於多層介質環境聚焦的模擬.............71 第四章 討論..............................................73 第五章 結論與未來工作....................................75 附錄A 連續方程式、動量方程式與狀態方程式.................76 附錄B 線性波動方程式的推導...............................83 附錄C 特徵阻抗...........................................88 附錄D 雷利積分式的推導...................................90 附錄E 聲強度與聲功率與波源表面狀態討論...................94 附錄F 聲波的折射和反射現象...............................99 參考文獻................................................103 | |
| dc.language.iso | zh-TW | |
| dc.subject | 擬反矩陣 | zh_TW |
| dc.subject | 高溫熱治療 | zh_TW |
| dc.subject | 聚焦點調變 | zh_TW |
| dc.subject | 超音波換能器 | zh_TW |
| dc.subject | 相位陣列 | zh_TW |
| dc.subject | ultrasound transducer | en |
| dc.subject | pseudoinverse | en |
| dc.subject | focus-steering | en |
| dc.subject | phased array | en |
| dc.subject | HIFU | en |
| dc.title | 用於肝臟腫瘤治療之曲面圓柱型超音波相位陣列換能器 | zh_TW |
| dc.title | Curved Cylindrical Ultrasound Phased Array for Liver Tumor Therapy | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 96-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 劉浩澧,陳永耀,陳文翔,王士豪 | |
| dc.subject.keyword | 高溫熱治療,超音波換能器,相位陣列,聚焦點調變,擬反矩陣, | zh_TW |
| dc.subject.keyword | HIFU,ultrasound transducer,phased array,focus-steering,pseudoinverse, | en |
| dc.relation.page | 104 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2008-07-31 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 醫學工程學研究所 | zh_TW |
| 顯示於系所單位： | 醫學工程學研究所 | |
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