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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/37612完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 李秀惠 | |
| dc.contributor.author | Po-Hau Chen | en |
| dc.contributor.author | 陳伯豪 | zh_TW |
| dc.date.accessioned | 2021-06-13T15:34:56Z | - |
| dc.date.available | 2011-07-21 | |
| dc.date.copyright | 2008-07-21 | |
| dc.date.issued | 2008 | |
| dc.date.submitted | 2008-07-11 | |
| dc.identifier.citation | [1] Donald H. Chace, Theodore A. Kalas, and Edwin W. Naylor, “Use of Tandem Mass Spectrometry for Multianalyte Screening of Dried Blood Specimens from Newborns”, Clin. Chem., Nov 2003; 49: 1797 - 1817.
[2] Schulze A, Lindner M, Kohlmuller D, Olgemoller K, Mayatepek E, Hoffmann GF, “Expanded newborn screening for inborn errors of metabolism by electrospray ionization-tandem mass spectrometry: results, outcome, and implications.”, Pediatrics, Vol. 111, No. 6, p.1399-1406, June 2003. [3] 2006 yearly report of Genetic Medical Department, unpublished [4] Chien-Ming Tu, Hsing-Yu Chang, Mei-Yu Tang, Faipei Lai, et al.,” The Design and Implementation of a Next Generation Information System for Newborn Screening”, HEALTHCOM 2007, June, 2007. [5] S.L. Hsieh, Feipei Lai, S.H. Hsieh et al, “An Integrated Healthcare Enterprise Information Portal and Healthcare Information System Framework”, IEEE EMBC, pp 4731-4734, 2006. [6] T. H. Yang, P. H. Cheng and et al., “A Scalable Multi-tier Architecture for the National Taiwan University Hospital Information System based on HL7 Standard”, HEALTHCOM, August, 2006. [7] System Questionnaire Evaluation , Genetic Medical Department, unpublished [8] Sung-Huai Hsieh, Sheau-Ling Hsieh, Yung-Ching Weng, Yin-Hsiu Chien, Zhenyu Wang, Po-Hao Chen, Hsing-Yu Chang, Feipei Lai, Wu-Liang Hwu, “Web Services Based Newborn Screening System with Support Vector Machines”, ICITA 2008 [9] Xiao-Ou Ping, Li-Fan Ko, Rung-Ji Shang, Faipei Lai, et al.,” Dynamic Messages Creation Method for HL7 Based Healthcare Information System”, HEALTHCOM 2007, June, 2007. [10] Y.C. Weng, S.L. Hsieh, S.H. Hsieh and et al, “Design and Enhance a Dynamic Healthcare Portal Site”, 2007, in preparation. [11] MSDN of Microsoft, Commercial documents. [12] http://en.wikipedia.org/wiki/Support_vector_machine [13]Gavin C. Cawley, Nicola L. C. Talbot, “Preventing Over-Fitting during Model Selection via Bayesian Regularisation of the Hyper-Parameters”, The Journal of Machine Learning Research Volume 8 , (May 2007)Pages: 841 – 861 [14] Isabelle Guyon, Andre Elisseeff, “An Introduction to Variable and Feature Selection”, Journal of Machine Learning Research 3 (2003) 1157-1182 [15] Yukun Bao and Zhitao Liu, “A Fast Grid Search Method in Support Vector Regression Forecasting Time Series”, Published book, ISBN 978-3-540-45485-4 [16] Asymptotic Behaviors of Support vector machines with Gaussian Kernal / S. Sathiya Keerthi and Chih-Jen Lin | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/37612 | - |
| dc.description.abstract | 本篇論文主要描述國立台灣大學醫學院附設醫院目前新生兒資訊系統開發的架構與狀況，使得樣本蒐集、檢驗、診斷、評估、治療、追蹤病例服務、篩檢數據資料庫管理、臨床研究、院際通訊的工作更為健全。最後以資料探勘的技術來建立一輔助協助診斷系統提升篩檢正確率。以此基於支持向量機的罕見疾病輔助診斷系統，甲基丙二酸血症為例，來分析此目前疑陽性極高的疾病。 | zh_TW |
| dc.description.abstract | The thesis aims to discuss about architecture and status of Newborn Screening Healthcare Information System of National Newborn Screening Center in National Taiwan University Hospital for further integrity and enhancements of sample collections, testing, diagnoses, evaluations, treatments or follow-up services, screening database management, as well as collaboration, communication among hospitals. Finally, we use data mining technology to build the diagnosis decision support system to improve the screening system accuracy. Then we examine the screening result of MMA which is high false-positive rate by the diagnosis decision support system based on support vector machine. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-13T15:34:56Z (GMT). No. of bitstreams: 1 ntu-97-R95922059-1.pdf: 1127935 bytes, checksum: 85d9189f2989511a2955a5b35f356b6f (MD5) Previous issue date: 2008 | en |
| dc.description.tableofcontents | Chapter 1 Introduction 1
1.1 Introduction 1 1.2 Background 2 1.3 Motivation and Objective 4 1.4 Thesis Organization 5 Chapter 2 Newborn Screening Healthcare Information System 6 2.1 NTUH HIS Architecture overview 6 2.2 Subsystem functionality. 7 2.3 Basic work sequence 10 2.4 Questionnaire 11 Chapter 3 Decision Support System Architecture and Data mining 12 3.1 SVM Web-Base Architecture 12 3.2 General Class Prediction with Supervised Method 17 3.3 The system progress and the detail of the design 18 3.4 Snapshot 31 Chapter 4 Experiment and Result 32 4.1 Material 32 4.2 Goal 34 4.3 Experiment progress 35 4.4 Experiment Result 36 4.4.1 Statistic components 36 4.4.2 Data set 37 4.4.3 Weight ratio 37 4.4.4 Grid Search with Features 38 4.4.5 Model parameters and model weight 42 4.4.6 Voting 43 4.4.7 Vote result compared with current method of NTUH 47 Chapter 5 Conclusion 48 Reference 49 | |
| dc.language.iso | en | |
| dc.title | 基於SVM遺傳疾病輔助篩檢系統 以台大醫院新生兒資訊系統為例 | zh_TW |
| dc.title | The inherited screening support system for MMA based on SVM– A Case Study of National Taiwan University Hospital Newborn Screening Healthcare Information System | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 96-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 賴飛羆 | |
| dc.contributor.oralexamcommittee | 張延任,李鴻璋,蔡坤霖 | |
| dc.subject.keyword | 新生兒篩檢,資訊系統,資料探勘,支持向量機,網路服務,甲基丙二酸血症, | zh_TW |
| dc.subject.keyword | Newborn Screening,Information System,Data Mining,Support Vector Machine,Web Services,MMA, | en |
| dc.relation.page | 50 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2008-07-11 | |
| dc.contributor.author-college | 電機資訊學院 | zh_TW |
| dc.contributor.author-dept | 資訊工程學研究所 | zh_TW |
| 顯示於系所單位： | 資訊工程學系 | |
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