請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/35600完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 李 敏 雄 | |
| dc.contributor.author | Hsiang-Yu Yeh | en |
| dc.contributor.author | 葉湘裕 | zh_TW |
| dc.date.accessioned | 2021-06-13T07:00:28Z | - |
| dc.date.available | 2006-08-01 | |
| dc.date.copyright | 2005-08-01 | |
| dc.date.issued | 2005 | |
| dc.date.submitted | 2005-07-27 | |
| dc.identifier.citation | 第六章 參考文獻
台灣地區食品營養成分資料庫 行政院衛生署編印 （1998） 李敏雄1997，卵磷脂之製備及應用。食品科學，24(6)：728-735。 食品化學 續光清編著 徐氏基金會 （1991） 菊地忠昭，石井茂孝，福島男兒，橫塚保。大豆多醣に關する食品化學的研究(第二報)麴菌酵素による大豆細胞壁多醣類の分解。農化1971, 45(5) : 228 - 234。 橫塚保主講、李政宏譯。醬油製造之原料蒸煮、製麴及醬醪發酵(上)。食品工業1989,21(4):24-37 Adlercreutz, H. Phytoestrogen and breast cancer. J. Steroid Biochem. Mol. Biol. 2002, 83, 113- 118. Adlercreutz., H. Western diet and Western disease: some hormonal and biochemical mechanisms and associations. Scand J Clin Lab Invest.1990 50, 3-10. American Institute of Nutrition. Second report of the ad hoc committee on standards for nutritional studies. J Nutr. 1980; 110:1726. Anderson, J. W.,Jone,A.E. and Riddell-Mason,S. Ten different dietary fibers have significant effects on serum and liver lipids of cholesterol-fed rats. J.Nutr.1994,124:78-83. Anderson, J. W.; Allgood, L. D.; Turner, J.; Oeltgen, P. R.; Daggy, B. P. Effect of psylluim on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia. Am. J.Clin. Nutr. 1999, 70, 466-473. Anderson, J.W., Johnstone, B.M., Cook- Newell, M.E. Meta-analysis of the effects of soy protein intake on serum lipids. N. ngl. J. Med. 1995. 333:276–82 Annison, G.; Topping, D. L. Nutritional role of resistant starch: chemical structure vs physiological function. Annu. Rev. Nutr. 1994, 14, 297-320. Anthony ,M.S., Clarkson, T.B., Hughes, C.L. Jr, Morgan,T.M., Burke ,G.L. Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. J.Nutr.1996. 126:43–50 Anthony, M. S.; Clarkson, T. B.; Williams, J. K Effects of soy isoflavones on atherosclerosis:Potential mechanisms. Am. J. Clin. Nutr. 1998, 68, 1390S-1393S. AOAC. Official Methods of Analysis, 16th ed.; Association of Official Analytical Chemists:Washington, DC, 1995. Armstrong, B. and Doll, R. Environmental factors and cancer incidence and mortality in different countries, with specific reference to dietary practices. Int. J. Cancer.1975, 15, 617-631. Arora, A.;Nair, M. G.; Strasburg, G. M. Antioxidant activities of isoflavone and their biological metabolites in a liposomal system. Arch. Biochem. Biophys. 1998, 356, 133-141. Baggott,J.E., Ha,T.,Vaughn,W.H.,Juliana, M.M., Hardin,J.M., Grubbs,C.J. Effect of miso (Japanese soybean paste) and NaCl on DMBA-induced rat mammary tumor. Nutr. Cancer.1990, 14 :103-109. Bao, B.; Chang, K. C. Carrot pulp chemical composition, color, and water-holding capacity as affected by blanching. J. Food Sci. 1994, 59, 1159-1161. Barnes S, Peterson TG, Coward L. Rationale for use of genistein containing soy matrices in chemoprevention trials for breast and prostate cancer. J Cell Biochem 1995;22:181–7. Bauchat, L. R. Food and Beverage Mycology. AVI Publishing Company, Inc. Westport, Connecticut. 1978. p.232. Bernfeld, D., Method in Enzymology. Academic press New York, 1995,1:149. Buege,J.A.,& Aust, S.D. Microsomal lipid peroxidation.In S. Floischer & L.Packer (Eds.) Methods in enzymology.1978, (Vol. LⅡ,52,pp.302-310). New York: Academic press. Burkitt D.P. Epidemiology of cancer of the colon and rectum. Cancer 1971,28:3-13. Carroll,K.K.. Review of clinical studies on cholesterol-lowering response to soy protein. J. Am. Diet. Assoc. 1991 91:820–827 Chau, C. F.; Huang, Y. L. Characterization of passion fruit seed fibres—a potential fibre source.Food Chem. 2004, 85, 189-194. Chau, C. F.; Huang, Y. L.; Lin, C.Y. Investigation of the cholesterol-lowering action of insoluble fibre derived from the peel of Citrus sinensis L. cv. Liucheng. Food Chem. 2004, 87, 361-366. Cook NR, Rosner BA. Sample size estimation for clinical trails with longitudinal measure: applications to studies of blood pressure. J Epidemiol biostat 1997, 2:65-74. Correa,P. Epidemiological correlations between diet and cancer frequency. Cancer Res. 1981,41, 3685-3690. Coward L., Barnes, N.C., Setchell, K.D.R. and Barnes, S. Genistein, daidzein, and their β-glycoside conjugate: antitumor isoflavones in soybean foods from American and Asian diet. J. Agric. Food Chem. 1993.41:1961-1967. Cummings, J. H.; Frolich, W. Dietary fibre intakes in Europe. In Metabolic and physiological aspects of dietary fibre in food, Cummings, J. H.; Frolich, W., Eds.; Commission of the European Communities: Luxembourg, 1993; pp 1. D'amico, G., Gentile, M., Manna, G., Fellin, G., Ciceri, R., Cofano, F., Petrini, C., Larvarda, F., Perolini, S., and Porrini, M. Effect of vegetarian soy diet on hyperlipidaemia in nephritic syndrome. Lancet. 1992.339:1131-7. Davignon, J.; Cohn, J.S. Triglycerides: a risk factor for coronary heart disease. Atherosclerosis 1996, 124(Suppl.), S57-S64. Davis CE, Rifkind BM, Brenner H,Gordon DJ. A single cholesterol measurement underestimates the risk of coronary heart disease. An empirical example from the Lipid Research Clinics Mortality Follow up Study. Journal of the American Medical Association . 1990;264:3044-6. Deng, G. Y.; Liu, Y. W.; He, G. Z.; Jiang, Z. M. Dietary fiber protection on intestinal barrier function. Asian J. Surg. 2000, 23, 90-96. Dietary Reference Intakes Proposed Definition of Dietary Fiber. Washington DC: National Academy Press; 2001:1-64. Duxbury D. D. Stabilized flax: high-fiber protein source. Food Process. 1993, 54, 93. East, J. The effect of genistein on the fertility of mice. J Endocrinol.1955;13:94–100. Eastwood,M.A.,Hamilton,D.Studies on the adsorption of bile salts to non-absorbed components of diet. Biochim Biophys Acta. 1968,152:165-173. Erdman, J.W. and Fordyce,E. Soy products and the human diet. Am.J.Clin.Nutr.1989,49:725-737. Espin, J. C.; Soler-Rivas, C.; Wichers, H. J. Characterization of the total free radical scavenger capacity of vegetable oils and oil fractions using 2,2-diphenyl-1-picrylhydrazil radical. J. Agric.Food Chem. 2000, 48, 648-656. Fitzpatrick, L.A. Soy isoflavones: hope or hype? Maturitas. 2003,44:S21-S29. Fang,Y.C.;Chen,B.H.;Huang,R.S.;Lu,Y.F. Effect of genistein supplementation on tissue genistein and lipid peroxidation of serum, liver and low-density lipoprotein in hamsters. J.Nutr.Biochem.2004,15:142–148. Folch J. Lees M. Sloane Stanley GH. A simple method for the isolation and purification of total lipids from animals tissue. J Biol Chem.1957, 226:497-509. Food and Nutrition Board (FNB), Institute of Medicine (IOM). Dietary reference intakes for energy, carbohydrates, fiber, fat, fatty acids, cholestrol, protein, and amino acids (macronutrients).National Academy of Science. Washington, D. C. 2002. Forsythe, W.A.Ⅲ. Comparison of dietary casein or soy protein effects on plasma lipids and hormone concentrations in the gerbil. J.Nutr. 1986. 116:1165–71. Friedlander Y, Kark JD, Stein Y. Variability of plasma lipids and lipoproteins: the Jerusalem Lipid Research Clinic Study. Clin Chem. 1985,31: 1121-6. Furda, I. Interaction of dietary fiber with lipids mechanistic theories and their limitations. In New Developments in Dietary Fiber; Furda, I.; Brine, C. J., Eds.; Plenum Press: New York, 1990; pp67-82. Ganji, V.; Betts, N. Fat, cholesterol, fiber and sodium intakes of US population: evaluation of diets reported in 1987-88 nationwide food consumption survey. Eur. J. Clin. Nutr. 1995, 49, 915-920. Giles,D. ,Wei H. Effects of structural related flavones /isoflavones on hydrogen peroxide production and oxidative DNA damage in phorbol ester-stimulated HL-60 cells. Nutr. Cancer. 1997. 29:77-82 Gordon, D. T. Functional properties vs. physiological action of total dietary fiber. Cereal Foods World. 1989,34, 517-525. Gotoh,T., Yamada,K., Yin,H., Ito, A., Kataoka,T., Dohi,K. Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A. Jpn.J. Cancer Res. 1998. 89: 137-142. Gourgue, C. M. P.; Champ, M. M. J.; Lozano, Y.; Delort-Laval, J. Dietary fibre from mango byproducts: characterization and hypoglycemic effects determined by in vitro methods. J. Agric.Food Chem. 1992, 40, 1864-1868. Green, J. and Kleeman, C. R. Role of bone in regulation of systemic acid-base balance. Kidney Int. 1991.39:9 Grigelmo-Miguek, M.; Martin-Belloso, O. Characterization of dietary fiber from orange juice extraction. Food Res.Int. 1999a, 31, 355-361 Grigelmo-Miguek, M.; Martin-Belloso, O. Comparison of dietary fiber from by-products of processing fruits and greens and from cereals. Lebensm.-Wiss. Technol. 1999b, 32, 503-508. Guo, T.L.; Zhang, X.L.; Bartolucci, E.; McCay, J.A., White, Jr. K. L. Genistein and methoxychlor modulate the cactivity of natural killer cells and the expression of phenotypic marker by thymocytes and splenocytes in F0 and F1 generations of Sprague-Dawley rats.Toxicology. 2002, 172, 205-215 Hecht SS, Carmella SG, Foiles PG, Murphy SE, Peterson LA Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans. Environ Health Perspect. 1993, 99, 57-63. Hodsges, R.e., Krehl, W.A., Stone, D. B., and Lopez, A. dietary carbohydrates and low cholesterol diets; effects on serum lipids of man. Am. J. Clin. Nutr. 1967. 20:198 Huff MW, Carroll KK. Effects of dietary protein on turnover, oxidation, and absorption of cholesterol, and on steroid excretion in rabbits. 1980,J. Lipid Res. 21:546–58 Hughes, J. S. Potential contribution of dry bean dietary fiber to health. Food Technol. 1991, 9, 5122-126. Izumi, T.; Piskula, M. K.; Osawa, S.; Obata, A.; Tobe, K.; Saito, M.; Kataoka, S.; Kubota, Y.;Kikuchi, M. Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans. J. Nutr. 2000, 130, 1695-1699. Jacobsen, B. K.; Knutsen, S. F.; Fraser, G. E. Does high soy milk intake reduce prostate cancer incidence, the adventist health study (United States). Cancer Causes Control. 1998, 9, 553-557. James L. Groff, Sareen S. Gropper. Advanced nutrition and human metabolism 3rd ed.Belmont,CA :West/Wadsworth, 2000. pp. 107 Jefferson, W.N., Newbold, R.R. Potential endocrine- modulating effects of various phytoestrogens in the diet. Nutrition. 2000;16:658–662. Jocobs DR, Barrett-Connor EB. Retest reliability of plasma cholesterol and triglyceride. Am J Epidemiol. 1982, 116:878-85 Kao,F.J.; Su,N.W.; Lee,M.H. Effect of water-to-bean ratio on the contents and compositions of isoflavones in tofu. J. Agric. Food Chem. 2004, 52, 2277-2281. Kennedy, A.R. The evidence for soybean products as cancer preventive agents. J.Nutr. 1995.125:733S-739S Klahr, S. 1990. Rental disease. Ch. 44. In Present Knowledge in Nutrition, M.L. Brown, L.J. Filer, Jr., H.A. Guthrie, O.A. Levander, D.B. McCormick, R.E. Olson, and R.D. Sttle (Ed.), p.377. International Life Science Institute- Nutrition Foundation, Washington, D.C. Kritchevsky,D., Story,J.A. Binding of bile salts in vivo by non-nutritive fiber. J. Nutr.1974,104:458-462. Kulling, S. E.; Lehmann, L.; Metzler, M. Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens. J. Chromatogr. B 2002, 83, 113-118. Kyrtopoulos S.A., Anderson L.M., Chhabra S.K., Souliotis V.L., Pletsa V. et al. DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance. Cancer Detect Prev. 1997, 21, 391-405 Law,M.R., Wald,N.J., Wu,T.,Hacksaw,A.,and Bailey,A. Systematic underestimation of association between serum cholesterol concentration and ischaemic heart disease in observational studies: data from the BUPA study. Br. Med. J. 1994. 308:363. Lee D.S., Lee S.H. Genistein, a soy isoflavine, is a potent –glucosidase inhibitor. FEBS Letters. 2001, 501, 84-86. Lee,S.C.; Prosky,L. Perspectives on complex carbohydrate definition. Cereal Foods World 1996,41, 88-89. Liang,C.T., Liu,C.H., Huang Y.T., Pang,V.F., Chen H. H. and Hong, C.C. The occurrence of spontaneous tumors on SPF and mice. J. Chin. Soc. Vet. Sci.1997, 23(6): 531-545 Lichtenstein, A.H. Soy protein isoflavone and cardiovascular disease risk. J. Nutr. 1998, 128, 1589-1592. Ling, W. H.; Jones, P.J.H.. Minireview. Dietary phytosterols: a review of metabolism, benefits and side effects. Life sciences. 1995.3:195-206. Lovati, M.R., Manzoni, C., Canavesi, A., et al. Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterolemic patients. J Clin Invest. 1987;80:1498 –1502. Luba L. Dumenco, Esther Allay, Kathleen Norton, Stanton L. Gerson The Prevention of Thymic Lymphomas in Transgenic Mice by Human O6-Alkylguanine-DNA Alkyltransferase. Science. 1993,259:219-222. Martin, P.M., Horwitz, K.B., Ryan, D.S., McGuire, W.L.. Phytoestrogen interaction with estrogen receptors in human breast ancer cells. Endocrinology 1978.103: 1860–67 McNeillie A.; Bieser,J. Hydrogen peroxide uses for the year 2000. Food Process. 1993,54:59-65. Messina, M, and Barnes, S. The role of soy products in reducing risk of cancer. J. Natl. Cancer Inst. 1991,83: 541-546. Messina, M, Persky, V, Setchell, KDR, and Barnes, S. Soy intake and cancer risk: a review of in vitro and in vivo data. Nutr. Cancer. 1994, 21, 113-131. Messina, M. J. Legumes and soybeans: overview of their nutritional profiles and health effects. .Am. J. Clin. Nutr. 1999, 70, 439S-450S. Messina, M. Soyfoods and soybean phyto-estrogens (isoflavones) as possible alternatives to hormone replacement therapy (HRT), Eur. J. Cancer 2000, 36, S71-S72. Mori, B.; Nakaji, S.; Sugawara, K.; Ohta, M.; Iwane, S.; Munakata, A.; Yoshida, Y.; Ohi, G. Proposal for recommended level of dietary fiber intake in Japan. Nutr. Res. 1996, 16, 53-60. Moron, D.; Melito, C.; Tovar, J. Effect of indigestible residue from foodstuffs on trypsin and pancreative α-amylase activity in vitro. J. Sci. Food Agric.1989, 47: 171-179. Morris E.R., Norton I. T. Polysaccharide aggregation in solutions and gels. In: Wyn-Jones E, Gomally J, eds. Aggregation Process in Solution. New York:Elsevier, 1983, pp. 15-31. Munomura,N., Mori,S., Sasaki,M. and Motai,H. Heating effects on flavor components in shoyu (soy sauce), in Abstr. Pap. Annu. Meet Agri. Chem. Soc. Jpn. 1983, pp.237. Murray, W. Huff and Kenneth K. Carroll.Effects of dietary protein on turnover, oxidation,and absorption of cholesterol, and on steroid excretion in rabbits J. Lipid Res. 1980. 21:546–58 Nagata Y, Ishiwaki N, Sugano M. 1982.Studies on the mechanism of the antihypercholesterolemia action of soy protein and soy protein-type amino acid mixtures in relation to their casein counterparts in rats. J. Nutr. 112:1614–25 Oakenfull, D. Physiochemical properties of dietary fiber: overview. In Handbook of Dietary Fiber; Cho, S. S.; Dreher, M. L., Eds.; Marcel Dekker: New York, 2001; pp 195-206. Orimo, H., Hashimoto, T., Shiraki, M., et al. Nation-wide survey of the hip fracture incidence in Japan. Jpn. Med. J. 1995,3707:27 Ou, S.; Kowk, K. C.; Li, Y. In vitro study of possible role of dietary fiber in lowering postprandial serum glucose. J. Agric. Food Chem. 2001, 49, 1026-1029. Penotti,M., Fabio,E.,Modena,A.B.,Rinaldi,M.Omodei,U. and Vigano,P. Effects of soy-derived isoflavone on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries.Fertility and sterility.2003.79:1112-1117. Potter, S. M. An overview of proposed mechanisms for the hypocholesterolemic effect of soy. J.Nutr. 1995,125:06S. Potter, S.M., Bakhit, R.M., Essex-Sorlie, D.L.,Weingartner, K.E., Chapman, K.M., et al.Depression of plasma cholesterol in men by consumption of baked products containing soy protein. Am. J. Clin.Nutr. 1993. 58:501–6 Potter, S.M.. Overview of proposed mechanisms for the hypocholesterolemic effect of soy. J. Nutr. 1995. 125:606–11S Potter,S.M., Baum,J.A., Teng,H., Stillman,R.J., Shay,N.F. Erdman Jr.,J.W. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women, Am.J.Clin.Nutr. 68 1998. 1375S–1379S. Pratt, D.E., Birac, P.M.. Source of antioxidant activity of soybeans and soy products. J. Food Sci. 1979. 44:1720–22 Price, K.R., Fenwick, G.R. Naturally occurring estrogens in foods-a review. Food Add Contam.1985:2:73–106. Przybyla, A. E. Formulating fiber into food. Food Eng. 1988, 60, 77-88. Racks, J.Ｊ. Honig, D. H. Sessa, D. J., and Cavins, J.F. Soybean whey proteins-recovery and amino acid analysis. J.Food Sci. 1971.36:10-13. Ralet, M.C.; Della Valle, G.; Thibault, J. F. Raw and extruded fiber from pea hulls. Part I:composition and physicochemical properties. Carbohydrate Polymers 1993, 20, 17-23. Ranhotra G. S.; Gelroth J. A.; Glaser, B. K. Energy value of resistant starch. J. Food Sci. 1996, 61,453-455. Rees, D.A. Polysaccharide Shapes. London: Chapman and Hall,1977. Ricciotti,H.A., Khaodhiar,L., Blackburn,G.L. Daidzein-rich isoflavone-aglycones for menopausal symptoms. International Journal of Gynecology and Obstetrics. 2005. 89: 65—66 Rolls, B. J.; Bell, E. A.; Castellanos, V. H.; Chow, M.; Pelkman, C. L.; Thorwart, M. L. Energy density but not fat content of foods affected energy intake in lean and obese woman. Am.J.Clin.Nutr. 1999, 69, 863-871. Ruiz-Larrea, M.B., Mohan.,A.R. Paganga,G. Miller,N.T., Bolwell,G.P., Rice-Evan. C.A. Antioxidant activity of phytoestrogen isoflavone. Free Radic. Res. 997.26:63-70 Saffhill, R., Margison, G.R. and O’Conmor, P.J. Mechanism of carcinogenesis induced by alkylating agents, Biochim. Biophys. Acta, 1985, 23,111-145. Schneeman, R. O. Dietary fiber:physical and chemical properties, methods of analysis and physiological effects. Food Technol, 1986,40,104-110. Setchell, K. D. R.; Cassidy, A. Dietary isoflavones: biological effects and relevance for human health. J. Nutr. 1999, 129, 748S-767S. Setchell, KDR, Borriello, SP, Hulme, P, Kirk, DN, and Axelson, M . Nonsteroidal Estrogens of Dietary Origin: Possible Roles in Hormone-Dependence Disease. Am. J. Clin. Nutr. 1984,40, 569-578. Shutt ,D.A., Cox, R.I.. Steroid and phytoestrogen binding to sheep uterine receptors in vitro. Endocrinology 1972.52:299–310 Slavin, J. L.; Jacobs, D.; Marquart, L.; Wiemer, K. The role of whole grains in disease prevention.J. Am. Diet. Assoc. 2001, 101, 780-785. Smith, D.R. Animal model: Nutrition and lipoprotein metabolism. Curr. Opin. Lipidol. 1998, 9, 3-6. Soloni ,F.G. Simplified manual micromethod for determination of serum triglycerides. Clin. Chem. 1971, 17(6),529-534. Sorgentini, D.A. and Wanger, J.R. Comperative study of structural characteristics and thermal behavior of shey and isolate soybean proteins. J.Food Biochem. 1999.23:489-507. Szuhaj, B.F.Lecithins, Chapters 11-14 and 17-18. Am. Chem. Soc., Chempaign, Illinois.1989 Tasker,T.E. and Potter,S.M. Effects of dietary protein source on plasma lipids, HMG-CoA reductase activity, and hepatic glutathione level in ferbils.J.Nutr.ciochem. 1993,4:458-462. Tham, D. M.; Gardner, C. D.; Haskell, W. L. Potential health benefits of dietary phytoestrogens: a review of clinical, epidemiological, and mechanistic evidence. J.Clin. Endocrinol. Metab. 1998, 83, 2223-2235. Thomas, M.; Crepeau, M. J.; Rumpunen, K.; Thibault, J. F. Dietary fiber and cell-wall polysaccharides in the fruits of Japanese quince. (Chaenomeles japonica). Lebensm.-Wiss. Technol. 2000, 33, 124-131. Ting, S. V. Alcohol-insoluble constituents of juice vesicles of citrus fruit. J.Food Sci. 1970, 35,757-761. Trichopoulos, Dimitrios; Li, Frederick P. What causes cancer? Scientific American. 1996,275(3) 80-87. Trowell HC, southgate DAT, Wolever TMS, et al. Dietary fiber redefined. Lancet. 1976,1:967. Vanhanen, H. T.; Blomqvist, S.; Ehnholm, C.; Hyvonen, M., Jauhiainen, M.; Torstila, I.; Miettinen, T.A. L. Lipid Res. 1993.34:1535-1544. Verdeal, K., Brown, R.R., Richardson, T., Ryan, D.S. Affinity of phytoestrogen for estradiol-binding proteins and effect of coumestrol on growth of 7,12- dimethylbenz(a) anthracene-induced rat mammary tumors. J. Natl. Cancer Inst. 1980.64:285–90 Verrillo, A. Teresa de A., Giarrusso, P. C., and LaRocca, S. Soybean protein diets in the management of Type Ⅱ hyperlipoproteinaemia. Atherosclerosis 1985.54:321. Wang H. J., Murphy P.A.. Isoflavone Content in Commercial Soybean Foods J. Agric.Food Chem. 1994,42(8) 1666-1673. Wang, H.; Murphy, P. A. Mass balance study of isoflavones during soybean processing. J. Agric.Food Chem. 1996, 44, 2377-2383. Wiseman, H.., O’Reilly, J. D.,Adlercreutz, H., Mallet, A. I.,Bowey, E. A.,Rowland, I. R., Sanders, T. A. Isoflavone phytoestrogens consumed in soy decrease F(2)-isoprostane concentrations and increase resistance of low-density lipoprotein to oxidation in humans. Am.J.Clin.Nutr. 2000,72,395–400. Wu, AH, Ziegler, RG, Horn-Ross, PL, Nomura, AMY, West, DW, et al. Tofu and risk of breast cancer in Asian-Americans. Cancer Epidemiol Biomarkers Prev.1996,5,901-906. Yamakoshi,J., Piskula, M.K., Izumi,T., Tobe K.,Saito,M., Katapka,S., Obata,A., Kikuchi,M.Isoflavone aglycone- rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits. J. Nutr. 2000, 130, 1887-1893. Yousef,M.I.;Kamel, K.I.; Esmail, A.M.;Baghdadi, H.H. Antioxidant activities and lipid lowering effects of isoflavone in male rabbits.Food and Chemical Toxicology. 2004, 42, 1497-1503. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/35600 | - |
| dc.description.abstract | 中文摘要
本研究利用榨出醬油後的醬油醪殘渣，經水洗、過篩、冷凍乾燥、研磨等步驟處理後製成膳食纖維粉末，經離體試驗分析其物化性並以動物模式探討降血脂之生理機能。 本研究脫鹽醬渣(desalted mash residue，DMR)的製備步驟簡易，製備流程包括：水洗、脫鹽、乾燥及研磨。將DMR以酵素方法測定其膳食纖維含量有52.4﹪，比較實驗組與控制組(纖維素cellulose)之物化性體積密度(bulk density )、保水性(water-holding capacity)、吸油性(oil-holding capacity)、膨脹性(swelling ability)及陽離子交換力(cation-exchange capacity) ，均有明顯差異。經HPLC分析DMR中可利用性(bioavailable)的異黃酮daidzein及genistein含量，分別為1200 to 1480 μmol/100 g (daidzein 約 3040-3759 μg/g ， genistein 約 3240-3996 μg/g)。 進一步以動物模式研究脫鹽醬渣(DMR)降血脂的效果，DMR分別以10%、15%、20% (w/w%)取代部份飼料，餵養十周齡的倉鼠(hamster)，經八週飼養後，分析控制組及實驗組(DMR取代部份飼料)的肝臟脂肪含量、血脂濃度，實驗組均顯著地比控制組低而且肝臟脂質過氧化測定 (Thiobarbituric acid-reactive substances ,TBARs) 及糞便膽固醇的排出量與控制組有顯著地差異。 本研究所製備的脫鹽醬渣(DMR)除了含豐富膳食纖維其物化性質經測定具有保水、吸油、抑制澱粉酶活性等作用，可做為食品工業中膳食纖維的來源外，其中含抗氧化功能的異黃酮，更增加脫鹽醬渣成為保健食品的價值。 | zh_TW |
| dc.description.abstract | ABSTRACT
Fiber-rich materials including desalted shoyu mash residue (briefly referred as desalted mash residue, (DMR), alcohol-insoluble solid (AIS) and water-insoluble solid (WIS) were prepared from shoyu mash residue, which is a filtration cake obtained during the isolation of shoyu by press filtration of fermented matrix in the final process. The DMR, AIS and WIS contain rich dietary fiber of 52.4, 61.5 and 54.7% by weight, respectively. The DMR, AIS and WIS all have significantly lower bulk densities, higher water-holding capacities, oil-holding capacities, swelling abilities and cation-exchange capacities than the control cellulose. These results indicated that the said fiber-rich materials prepared in this study all have the desired physicochemical properties for being used as satisfactory sources of dietary fibers or low-calorie bulk ingredients in food applications requiring oil and moisture retention. Furthermore, the said fiber-rich materials also have high contents of isoflavones, mainly daidzein and genistein that are considered as the most bioavailable phytoestrogens, with a total amount of about 1200 to 1480 μmol/100 g (equal to daidzein of ca. 3040-3759 μg/g, or genistein of 3240-3996 μg/g). The effects of DMR-supplemneted diet on cholesterol absorption in hamsters were investigated and compared with those of a cellulose-containing diet, as control. Comparison of test and control treatments indicated an elevated high-density lipoprotein (HDL) cholesterol concentration and a significantly reduced serum low-density lipoprotein, triglyceride, total liver lipid and liver cholesterol on the test diet. The significant fecal bile acids excretion of test diets may be contributed to the hypolipidemic effects of DMR. Furthermore DMR also contains rich amount of isoflavone, genestein and daidzein, which are considered as the most bioavailable phytoestrogen and antioxidant. The results revealed that the said fiber-rich materials might be a potent fiber sources for health foods. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-13T07:00:28Z (GMT). No. of bitstreams: 1 ntu-94-D86623502-1.pdf: 10783387 bytes, checksum: fc11006d4fece3fb144737f8380101e7 (MD5) Previous issue date: 2005 | en |
| dc.description.tableofcontents | 目 錄
目次 Ⅰ 圖次 Ⅹ 表次 Ⅵ 誌謝 Ⅶ 中文摘要 1 英文摘要 3 第一章 序言 5 第二章 文獻整理 7 壹、膳食纖維 7 一、膳食纖維的定義與結構 7 二、膳食纖維的物化性質 8 1. 溶解度 8 2. 保水能力 8 3. 吸附離子能力 11 三、膳食纖維的水溶性與生理作用 11 1. 膳食纖維的水溶性 11 （1）水溶性纖維 12 （2）非水溶性膳食纖維 13 2. 膳食纖維的生理功能 14 （1）水溶性膳食纖維 14 （2）食物纖維的保水能力 14 （3）食物纖維的保水能力 15 （4）纖維降低營養素(葡萄糖)擴散速率 15 （5）纖維降低脂肪吸收 15 貳、醬油的製造 16 參、黃豆的機能性成份 18 一、黃豆機能性成分之研究與開發 18 1.大豆卵磷脂及其生理機能 18 2.維生素E及植物固醇生理活性 20 二、黃豆蛋白質（soybean protein）之機能性 21 1.黃豆蛋白質（soybean protein）的生理活性 21 2.豆清蛋白（soybean whey protein）之生理活性 23 三、 黃豆中的類黃酮及含量 23 1.Falvonoids 23 2.大豆isoflavones的含量 23 3.異黃酮(isoflavones)結構與種類 24 4.異黃酮(isoflavones)的生理活性 24 研究架構 29 第三章 材料與方法 30 壹. 材料 30 一、 化學藥品 30 二、 儀器 31 三、 動物實驗材料 32 貳.方法 32 一、 脫鹽醬油醪殘渣製備 32 二、 酒精不溶固形物(AIS)及水不溶固形物(WIS)之製備 32 三、 脫鹽醬油醪殘渣一般成分分析 33 1.粗蛋白質測定 (AOAC,1995) 33 2.粗脂肪測定 (AOAC,1995) 34 3.水分的測定 (AOAC,1995) 34 4.灰分測定 (AOAC,1995) 35 5.碳水化合物(無氮化合物) 35 6.膳食纖維含量測定（AOAC,1995） 35 （1）不溶性膳食纖維(Insoluble dietary fiber) 35 （2）水溶性膳食纖維(Soluble dietary fiber) 36 四、 膳食纖維的物化性分析 36 1.容積密度(bulk density) 36 2.膨脹性(swelling property) 36 3.陽離子交換能力(cation-exchange capacity) 37 4.吸水力(water-holding capacities,WHCs) 37 5.吸油力(oil-holding capacities,OHCs) 37 五、 脫鹽醬油醪殘渣纖維對葡萄糖的吸附作用 37 六、 脫鹽醬油醪殘渣纖維對α-amylase活性的影響 38 七、 脫鹽醬油醪殘渣異黃酮的萃取 38 八、 異黃酮之HPLC分析 39 九、 脫鹽醬油醪殘渣纖維物質捕捉自由基之能力測定 39 1.樣品萃取 39 2.清除α-α-Diphenyl-β- -picrylhydrazyl(DPPH) 自由基能力 40 十一、 飼料配製 40 十二、 動物飼養 40 十三、 生化檢驗分析 41 1.血液分析相項目 41 2.肝臟脂質分析 42 3.糞便膽固醇分析 42 4.脂質過氧化測定 42 第四章 結果與討論 44 壹. 脫鹽醬油醪殘渣纖維的物化性質及其在離體實驗的降血糖和抗氧化效果 44 一、 脫鹽醬渣及其酒精不溶固形物與水不溶固形物之產率與一般成份分析 44 二、 脫鹽醬渣及其酒精不溶固形物與水不溶固形物之一般成份分析 44 三、 脫鹽醬渣及其酒精不溶固形物與水不溶固形物之物化性質分析 48 四、 膳食纖維與葡萄糖結合量及對α澱粉酶活性的影響 48 五、膳食纖維物質異黃酮含量分析 50 六、脫鹽醬渣甲醇萃取物捕獲自由基的效果 53 貳. 醬渣纖維降低倉鼠血膽固醇的效果 57 一、飼料組成與生長 57 二、血液生化檢查 60 三、肝臟脂肪與膽固醇測定 61 四、肝臟脂肪過氧化試驗 61 第五章 結論 65 第六章 參考文獻 66 英文縮寫(ABBREVATIONS USED) 86 附錄 87 1.為本論文已經發表在期刊(J. Agric. Food Chem.2005, 88 53, 4361-4366) 的內容。 2.探討黃豆粉添加飼糧對由NMU (N-nitroso- N-methylurea) 誘導ICR小鼠發生胸腺淋巴瘤之影響。 89 一、前言 89 二、材料與方法 89 1. 飼料配製 89 2. 動物飼養 90 3. 致腫瘤操作 90 4. 動物犧牲與樣品收集、分析 92 5. 組織病理切片流程 92 三、結果與討論 94 | |
| dc.language.iso | zh-TW | |
| dc.subject | 醬油醪 | zh_TW |
| dc.subject | 理化性質 | zh_TW |
| dc.subject | Physicochemical | en |
| dc.subject | Soy Sauce Mash | en |
| dc.title | 醬油醪殘渣之理化性質與機能性之研究 | zh_TW |
| dc.title | Studies on the Physicochemical and Biofunctional Properties of Soy Sauce Mash Residue | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 93-2 | |
| dc.description.degree | 博士 | |
| dc.contributor.oralexamcommittee | 胡 淼 琳,邱 志 輝,林 子 清,黃 健 雄,賴 喜 美,蘇 南 維 | |
| dc.subject.keyword | 醬油醪,理化性質, | zh_TW |
| dc.subject.keyword | Soy Sauce Mash,Physicochemical, | en |
| dc.relation.page | 101 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2005-07-27 | |
| dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
| dc.contributor.author-dept | 農業化學研究所 | zh_TW |
| 顯示於系所單位： | 農業化學系 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-94-1.pdf 未授權公開取用 | 10.53 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。