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| ???org.dspace.app.webui.jsptag.ItemTag.dcfield??? | Value | Language |
|---|---|---|
| dc.contributor.advisor | 于宏燦 | |
| dc.contributor.author | Hsiao-Pei Lu | en |
| dc.contributor.author | 呂曉沛 | zh_TW |
| dc.date.accessioned | 2021-06-13T06:06:33Z | - |
| dc.date.available | 2006-07-03 | |
| dc.date.copyright | 2006-07-03 | |
| dc.date.issued | 2006 | |
| dc.date.submitted | 2006-06-12 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/34397 | - |
| dc.description.abstract | 本研究使用野外採集之台灣山區鼠類作為實驗對象，用以探討其消化道內的各類菌種。利用PCR方法增幅原核生物特有的16S rRNA基因片段，並透過 sequencing的分子生物技術，獲得大量序列進行比對分析，建立不同腸道樣本之細菌與古生菌的16S rRNA基因資料庫。
選用巢鼠與高山田鼠作為消化道古生菌相之研究對象。分析十個腸道樣本，獲得共117條古生菌序列，全部序列彼此間的相似度超過98%，定義為同一個操作分類單元 (OTU)，與NCBI資料庫的比對結果，相近於Crenarchaeota門的group C1b，為嗜中溫性之土壤古生菌群。 選用台灣森鼠作為消化道細菌相之研究對象。分析小腸、盲腸與大腸樣本，獲得共386條細菌序列，可分為11的大群，佔細菌界中的6個門 (phylum)，分別為Firmicutes (42.26%)、Proteobacteria (42.23%)、Deinococcus-Thermus (9.84%)、Verrucomicrobia (2.33%)、Cyanobacteria (1.81%) 與Actinobacteria (0.52%)。各項多樣性分析結果均顯示：森鼠盲腸與大腸樣本所含之細菌物種，遠較小腸樣本來得豐富多樣。 所得之古生菌與細菌的16S rRNA基因資料庫，可作為山區老鼠族群之消化道菌相研究的基礎資料。未來可比較不同物種與不同個體之間消化道菌相組成的差異程度，並用以探討古生菌與細菌之間的交互作用與比例關係，藉此了解野生動物體內之共生性微生物所扮演的角色功能。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2021-06-13T06:06:33Z (GMT). No. of bitstreams: 1 ntu-95-R93b41003-1.pdf: 707676 bytes, checksum: 74a7dbcd5e84b72e4489001edfa5241c (MD5) Previous issue date: 2006 | en |
| dc.description.tableofcontents | 致謝 …Ⅰ
摘要 …Ⅲ 目錄 …Ⅳ 第一章 哺乳動物的消化道菌相之相關研究 1. 哺乳動物之消化系統介紹 1 2. 消化道各區域的菌相環境 3 3. 消化道中微生物的群落組成 4 4. 影響消化道菌相組成之因素 10 5. 研究主題與研究方向 14 6. 參考文獻 16 第二章 巢鼠與高山田鼠的消化道古生菌相研究 1. 前言 20 2. 材料方法 22 3. 結果 27 4. 討論 29 5. 總結 34 6. 參考文獻 35 7. 附表 38 8. 附圖 41 第三章 台灣森鼠的消化道細菌相研究 1. 前言 43 2. 材料方法 44 3. 結果 50 4. 討論 59 5. 總結 64 6. 參考文獻 65 7. 附表 69 8. 附圖 74 | |
| dc.language.iso | zh-TW | |
| dc.title | 山區鼠類的消化道菌相研究 | zh_TW |
| dc.title | Microbial community in gastrointestinal tracts of wild mice in mountain areas | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 94-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳俊堯,張慧羽,林雨德,羅竹芳 | |
| dc.subject.keyword | 巢鼠,田鼠,森鼠,細菌,古生菌,消化道,腸道,微生物, | zh_TW |
| dc.subject.keyword | archaea,bacteria,mouse,intestine,gut,microflora,Taiwan, | en |
| dc.relation.page | 78 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2006-06-12 | |
| dc.contributor.author-college | 生命科學院 | zh_TW |
| dc.contributor.author-dept | 動物學研究研究所 | zh_TW |
| dc.date.embargo-lift | 2300-01-01 | - |
| Appears in Collections: | 動物學研究所 | |
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