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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 潘永寧(Yung-Ning Pan) | |
dc.contributor.author | Chen-Ting Chang | en |
dc.contributor.author | 張振庭 | zh_TW |
dc.date.accessioned | 2021-06-13T04:47:36Z | - |
dc.date.available | 2007-07-27 | |
dc.date.copyright | 2006-07-27 | |
dc.date.issued | 2006 | |
dc.date.submitted | 2006-07-17 | |
dc.identifier.citation | 【1】 洪炎輝, 生醫用鈦合金之合金開發及機械性質研究, 國立台灣大學機械工程學研究所博士論文, 2004.
【2】 D. R. Sumner and J. O. Galante: Clin. Orthop. Relat. Res. 274 202-212 (1992). 【3】 A. Sarmiento, G. A. Zych, L. L. Latta and R. R. Tarr: Clin. Orthop. Relat. Res. 144, 166-173 (1979). 【4】 M. F. Semlitsch, H. Weber, R. M. Streicher and R. Schon: Biomaterials 13, 781-788 (1992). 【5】 R. M. Pillar: Biomaterials 12, 95-100 (1991). 【6】 Mei-Shiou Chen, Geng-Liang Ou, Jeng-Shiung Chen, et al., Chin Dent J 23(5), 392-403 (2004). 【7】 Lynch SE, Buser D, Hernandez RA, Weber HP, Stich H, Fox CH, Williams RC. Effects of the platelet-derived growth factor/insulin-like growth factor I combination on bone regeneration around titanium dental implants, results of a pilot study in beagle dogs. J Periodontal, 62: 710-716, 1991. 【8】 Swart KM, Keller JC, Wightman JP, Draughn RA, Stanford CM, Michaels CM. Short-term plasma-cleaning treatments enhance in vitro osteoblast attachment to titanium. J Oral Implantol, 18: 130-137, 1992. 【9】 Aronsson BO, Lausmaa J, Kasemo B. Glow discharge plasma treatment for surface cleaning and modification of metallic biomaterials. J Biomed Mater Res, 35: 49-73 1997. 【10】 Shibata Y, Fujimori S. Glow discharge treatment is effective for cell proliferation and differentiation of osteoblast-like cells on titanium surface. J Showa Univ Dent Soc, 20: 24-29, 2000. 【11】 Shibata Y, Miyazaki T. Anode glow discharge plasma treatment enhances calcium phosphate adsorption onto titanium plates. J Dent Res, 81:841-847, 2002. 【12】 Shibata Y, Hosaka M, Kawai H, Miyazaki T. Glow discharge plasma treatment of titanium plates enhances adhesion of osteoblast-like cells to the plates through the integrin-mediated mechanism. Int J Oral Maxillofac Implants, 17: 771-777, 2002. 【13】 Kasemo B. Lausmaa J. Material-tissue interfaces: The role of surface properties and processes. Environ Health Perspect 102(Suppl 5), 41-45, 1994. 【14】 McAlarney ME, Oshiro MA. Effects of titanium dioxide passive film crystal structure, thickness, and crystallinity on C3 adsorption. Int J Oral Maxillofac Implants. 11: 73-80, 1996. 【15】 Rajaraman R, Rounds DE, Yen SPS, Rembaum A.A scanning electron microscope study of cell adhesion and spreading in vitro. Exptl Cell Res, 88: 327-339,1974. 【16】 Orsini G, Assenza B, Scarano A, Piatelli M, Piatelli A. Surface analysis of machined versus sandblasted and acid-etched titanium implants. Int J Oral Maxillofac Impants, 15: 779-784, 2000. 【17】 D.Velten, E. Eisenbarth and N. Schanne, et al., Materials In Medicine 15, 457-561 (2004). 【18】 Wei Zhou, Xiaoxia Zhong, Xiaochen Wu, et al., Surf. Coat. Technol. 200, 6155-6160 (2006). 【19】 HH Huang, CT Ho, HT Yu, et al., Chin Dent J 23(3), 210-220 (2004). | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/33564 | - |
dc.description.abstract | 鈦及鈦合金因為具有低楊氏係數,良好的降伏強度,優異的腐蝕抗阻及生物相容性,故廣泛應用於生醫設備及元件上。本研究選用具優良機械性質之Ti-40Nb-1Hf合金,探討低溫電漿處理對於表層微結構之影響,並進而探究其生物相容性。X-ray繞射圖譜顯示Ti-40Nb-1Hf合金表層有β相結晶狀組織之氧化層,且β相繞射峰值隨著電漿處理功率的增加而變大。另由XPS分析得知,Ti-40Nb-1Hf合金經由電漿處理後,會提升氧化層中TiO2及Nb2O5之含量,TiO2及Nb2O5具有相當高的抗腐蝕性質,因此預期會有助於提升生物相容性。AFM和接觸角/表面能的分析結果顯示Ti-40Nb-1Hf合金經由電漿處理後,獲得較佳表面粗糙度及接觸角,隨著電漿處理功率增加,表面型貌及表面潤濕性愈佳。於生物相容性研究上,藉由細胞數量分析與母骨細胞生長情形之SEM觀察,顯示Ti-40Nb-1Hf合金經由電漿處理後,細胞活性較未處理者高,故生物相容性亦應有所增進。 | zh_TW |
dc.description.abstract | Titanium and its alloys are widely used in biomedical equipments and components, due to their properties such as relatively lower modulus, good fatigue strength, corrosion resistance and biocompatibility. The aim of this study was to investigate the effect of low temperature plasma treatment on the surface characteristics of Ti-40Nb-1Hf alloy, and further to examine the biocompatibility of the treated alloy. The crystal structure, chemical compositions, surface topographies, wettability as well as cell morphology were investigated by using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), water contact angle measurement and scanning electron microscope (SEM).
The results of XRD analysis indicate that plasma oxidation induces the formation of titanium oxide. Furthermore, the intensity of the β-Ti peak increases with increasing plasma energy. In addition, the XPS data reveal that the rate of TiO2 and Nb2O5 in the oxide layer increases after being O2 plasma treated. Surface properties were studied by the atomic force microscopy (AFM) and contact angle analysis. The results show that as the power of O2 plasma increases, both the surface roughness and water contact angle decrease. Regarding the biocompatibility, the cell count analysis and SEM observations of the plasma-treated Ti-40Nb-1Hf alloy show that the cell activity of specimens with plasma treatment is better than those without plasma treatment, and hence, the biocompatibility of the Ti-40Nb-1Hf alloy can be expected to improve. | en |
dc.description.provenance | Made available in DSpace on 2021-06-13T04:47:36Z (GMT). No. of bitstreams: 1 ntu-95-R93522723-1.pdf: 13231482 bytes, checksum: ae5b1d2d5f81cf6766585fc9c474c60d (MD5) Previous issue date: 2006 | en |
dc.description.tableofcontents | 摘要 i
英文摘要 ii 目錄 iii 表目錄 v 圖目錄 vi 第一章 前言 01 第二章 文獻回顧 03 2.1生醫材料之生物相容性 03 2.2鈦和鈦合金簡介 04 2.2.1生醫鈦合金之發展 05 2.3電漿簡介 07 2.3.1電漿定義 09 2.3.2電漿物理原理及性質 09 2.3.3電漿分類 10 2.3.4電漿技術 11 2.3.5低溫電漿表面改質 12 2.3.6低溫電漿在生醫材料上之應用 13 2.3.7電漿改質之相關文獻 15 2.4細胞生長形態 16 第三章 實驗方法 22 3.1合金配置 22 3.2試片準備 22 3.3電漿實驗 23 3.4 X-ray繞射分析 23 3.5 XPS分析 24 3.6 AFM分析 24 3.7表面能/接觸角分析 24 3.8細胞培植 25 3.9 SEM分析 25 第四章 實驗結果與討論 27 4.1 Ti-40Nb-xHf合金之顯微組織分析 27 4.2低溫電漿處理 27 4.3表面顯微結構 28 4.4表面性質分析 30 4.4.1表面粗糙度分析 30 4.4.2表面能/接觸角分析 31 4.5生物相容性分析 32 4.5.1細胞數量分析 32 4.5.2細胞生長 33 第五章 結論 53 第六章 未來研究方向 54 參考文獻 55 | |
dc.language.iso | zh-TW | |
dc.title | 低溫電漿處理對Ti-40Nb-1Hf合金之表層微結構之影響研究 | zh_TW |
dc.title | The effect of low temperature plasma treatment on the surface characteristics of Ti-40Nb-1Hf alloy | en |
dc.type | Thesis | |
dc.date.schoolyear | 94-2 | |
dc.description.degree | 碩士 | |
dc.contributor.coadvisor | 歐耿良(Keng-Liang Ou) | |
dc.contributor.oralexamcommittee | 呂炫?(Shiuan-Kuen Liu) | |
dc.subject.keyword | Ti-40Nb-1Hf合金,低溫電漿,生物相容性, | zh_TW |
dc.subject.keyword | Ti-40Nb-1Hf,low temperature plasma,biocompatibility, | en |
dc.relation.page | 57 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2006-07-17 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
顯示於系所單位: | 機械工程學系 |
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