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  1. NTU Theses and Dissertations Repository
  2. 公共衛生學院
  3. 流行病學與預防醫學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/32893
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dc.contributor.advisor賴美淑,謝長堯
dc.contributor.authorChih-Chung Chenen
dc.contributor.author陳志忠zh_TW
dc.date.accessioned2021-06-13T04:18:20Z-
dc.date.available2008-08-03
dc.date.copyright2006-08-03
dc.date.issued2006
dc.date.submitted2006-07-24
dc.identifier.citation1. Martin JA, Hamilton BE, Ventura et al. Births: Final data for 2000. Natl Vital Stat Rep 2002;50:1–101.
2. Dobson R. Caesarean section rate in England and Wales hits 21%. BMJ 2001;323:951.
3. Cunningham FG, Gant NF, Leveno KJ et al. Williams obstetrics. 21st ed. Toronto: McGraw-Hill, 2001:537–563.
4. Sachs BP, Castro MA. The risks of lowering the cesarean delivery rate. N Engl J Med 1999;340:54–57.
5. Cnattingius R, Cnattingius S, Notzon FC. Obstacles to reducing cesarean rates in a low cesarean setting: The effect of maternal age, height and weight. Obstet Gynecol 1998;92:501–506.
6. Ehrenberg HM, Dierker L, Milluzzi C et al. Prevalence of maternal obesity in an urban center. Am J Obstet Gynecol 2002; 187:1189–1193.
7. Thorsdottir I, Torfadottir JE, Birgisdottir BE et al. Weight gain in women of normal weight before pregnancy: complications in pregnancy or delivery and birth outcome. Obstet Gynecol 2002;99:799–806.
8. Boulet SL, Alexander GR, Salihu HM et al. Macrosomic births in the united states: determinants, outcomes, and proposed grades of risk. Am J Obstet Gynecol 2003;188:1372– 1378.
9. Rhodes JC, Schoendorf KC, Parker JD. Contribution of excess weight gain during pregnancy and macrosomia to the cesarean delivery rate, 1990–2000. Pediatrics 2003;111:1181–1185.
10. Myles TD, Gooch J, Santolaya J. Obesity as an independent risk factor for infectious morbidity in patients who undergo cesarean delivery. Obstet Gynecol 2002;100:959-964.
11. Stotland NE, Hopkins LM, Caughey AB. Gestational weight gain, macrosomia, and risk of cesarean birth in nondiabetic nulliparas. Obstet Gynecol 2004;104:671-677.
12. Kaiser PS, Kirby RS. Obesity as a risk factor for cesarean in a low-risk population. Obstet Gynecol 2001;97:39-43.
13. Jensen DM, Sorensen B, Ovesen P et al. Gestational weight gain and pregnancy outcomes in 481 obese glucose-tolerant women. Diabetes Care 2005;28:2118-2122.
14. Joseph KS, Young DC, Dodds L et al. Changes in maternal characteristics and obstetric practice and recent increases in primary cesarean delivery. Obstet Gynecol 2003;102:791-800.
15. Edwards LE, Hellerstedt WL, Alton IR et al. Pregnancy complications and birth outcomes in obese and normal-weight women: effects of gestational weight change. Obstet Gynecol 1996;87:389-394.
16. Witter FR, Caulfield LE, Stoltzfus RJ. Influence of maternal anthropometric status and birth weight on the risk of cesarean delivery. Obstet Gynecol 1995;85:947-951.
17. Wong W, Tang NLS, Lau TK et al. A new recommendation for maternal weight gain in Chinese women. J Am Dietet Assoc 2000;100:791-796.
18. Chen G, Uryasev S, Young TK. On prediction of the cesarean delivery risk in a large private practice. Am J Obstet Gynecol 2004;191:617-625.
19. Shepard MJ, Saftlas AF, Leo-Summers L et al. Maternal anthropometric factors and risk of primary cesarean delivery. Am J Public Health 1998;88:1534-1538.
20. Vahratian A, Siega-Riz AM, Savitz DA et al. Maternal pre-pregnancy overweight and obesity and the risk of cesarean delivery in nulliparous Women. Ann Epidemiol 2005;15:467-474.
21. Vahratian A, Zhang J, Troendle JF et al. Maternal prepregnancy overweight and obesity and the pattern of labor progression in term mulliparous women. Obstet Gynecol 2004;104:943-951.
22. Kiran TSU, Hemmadi S, Bethel J et al. Outcome of pregnancy in a woman with an increased body mass index. BJOG 2005;112:768-772.
23. Dempsey JC, Ashiny Z, Qiu CF et al. Maternal pre-pregnancy overweight status and obesity as risk factors for cesarean delivery. J matern-fetal neonat Med. 2005;17:179-185.
24. Weiss JL, Malone FD, Emig D et al. Obesity, obstetric complications and cesarean delivery rate – a population-based screening study. Am J Obstet Gynecol 2004;190:1091-1097.
25. Rode L, Nilas L, Wojdemann K et al. Obesity-related complications in Danish single cephalic term pregnancies. Obstet Gynecol 2005;105:537-542.
26. Jensen DM, Damm P, Sorensen B et al. Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women. Am J Obstet Gynecol 2003;189:239-244.
27. Young TK, Woodmansee B. Factors that are associated with cesarean delivery in a large private practice: the importance of prepregnancy body mass index and weight gain. Am J Obstet Gynecol 2002;187:312-320.
28. Baeten JM, Bukusi EA, Lambe M. Pregnancy complications and outcomes among overweight and obese nulliparous women. Am J Public Health 2001;91:436-440.
29. Sebire NJ, Jolly M, Harris JP et al. Maternal obesity and pregnancy outcome: a study of 287213 pregnancies in London. Int J Obesity 2001;25:1175-1182.
30. Crane SS, Wojtowycz MA, Dye TD et al. Association between pre-pregnancy obesity and the risk of cesarean delivery. Obstet Gynecol 1997;89:213-216.
31. LaCourisiere DY, Bloebaum L, Duncan JD et al. Population-based trends and correlates of maternal overweight and obesity, Utah 1991-2001. Am J Obstet Gynecol 2005;192:832-839.
32. Ehrenberg HM, Durnwald CP, Catalano P et al. The influence of obesity and diabetes on the risk of cesarean delivery. Am J Obstet Gynecol 2004;191:969-974.
33. Durnwald CP, Ehrenberg HM, Mercer BM. The impact of maternal obesity and weight gain on vaginal birth after cesarean section success. Am J Obstet Gynecol 2004;191:954-957.
34. Jensen H, Agger AO, Rasmussen KL. The influence of prepregnancy body mass index on labor complications. Acta Obstet Gynecol Scand 1999;78:799-802.
35. Sheiner E, Levy A, Menes TS et al. Maternal obesity as an independent risk factor for cesarean delivery. Paedia Perinat Epidemiol 2004;18:196-201.
36. Kabiru W, Raynor BD. Obstetric outcomes associated with increase in BMI category during pregnancy. Am J Obstet Gynecol 2004;191:928-32.
37. Cunningham FG, Gant NF, Leveno KJ et al. Williams obstetrics. 21st ed. Toronto: McGraw-Hill, 2001:5.
38. Miller DA. Is advanced maternal age an independent risk factor for uteroplacental insufficiency? Am J Obstet Gynecol 2005;192:1974-80.
39. Kirchengast S, Hartmann B. Advanced maternal age is not only associated with newborn somatometrics but also with the mode of delivery. Ann Human Biol 2003;30:1-12.
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/32893-
dc.description.abstract研究背景:近年來歐美等國家之剖腹產率有逐年增加的趨勢,而臺灣地區在全民健保施行後剖腹生產的比率仍然居高不下。文獻回顧顯示懷孕前肥胖與懷孕期間體重增加過多可能與提高剖腹生產的風險有關。
研究目的:檢視懷孕期間身體質量指數變化與初次非計畫性剖腹生產風險之相關性。
研究設計:蒐集所有從2003年12月1日至2005年4月30日於臺北縣某一區域教學醫院生產之產婦及其生產資料進行回顧性世代研究。排除早產與計畫性剖腹生產之案例,如前胎剖腹生產、胎位不正、多胞胎等。利用單變項以及多變項邏輯性迴歸分析(1)懷孕前身體質量指數、(2)懷孕期間增重量、(3)懷孕期間增重比例、(4)懷孕期間身體質量指數變化等四項因素與初次非計畫性剖腹生產風險之相關性。
研究結果:研究期間共有1960人次產婦生產,總剖婦產率為33.5%。排除早產與計畫性剖腹生產之案例後,共有產婦1392人次,初次非計畫性剖腹產率為11.35%。多變項邏輯性迴歸分析顯示:懷孕前身體質量指數越高 (OR:1.10, 95% CIs: 1.04~1.15)及懷孕期間增重量越多 (OR:1.05, 95% CIs: 1.01~1.09)之孕婦,初次非計畫性剖腹生產的風險越高。懷孕期間身體質量指數增加越多也與初次非計畫性剖腹生產的風險提高相關,但顯著相關僅限於未滿35歲之非高齡產婦 (OR:1.13, 95% CIs: 1.03~1.25)。
結論:非高齡產婦之懷孕期間身體質量指數變化與初次非計畫性剖腹生產風險存在顯著相關性。
zh_TW
dc.description.abstractBackground: Over the last few years, cesarean delivery rates have increased in several well-industrialized countries, such as the United States and England. According to the data of the National Health Insurance in Taiwan, the rates of cesarean delivery maintained high from 33.68% in 1995 to 32.67% in 2003. Obesity and excess gestational weight gain have been associated with multiple adverse perinatal outcomes, including increased rates of cesarean delivery.
Objective: The purpose of this study was to investigate effect of BMI change during pregnancy on risk for cesarean delivery.
Study design: A retrospective cohort study was conducted from December 1, 2003 to April 30, 2005. All women delivered in a regional hospital in Taipei County were eligible. Preterm deliveries and planned cesarean deliveries were excluded. Univariate and multivariate logistic regressions were introduced.
Results: During study period, 1960 women delivered and total cesarean delivery rate was 33.5%. After exclusion, 1392 women were retained in this study. Primary unplanned cesarean delivery rate was 11.35%. Increased risks of cesarean delivery was associated with higher pre-pregnancy BMI (OR:1.10, 95% CIs: 1.04~1.15) and excessive gestational weight gain (OR:1.05, 95% CIs: 1.01~1.09). Among women aged less than 35 year, risks of cesarean delivery was associated with BMI increase during pregnancy (OR:1.13, 95% CIs: 1.03~1.25).
Conclusion: BMI change during pregnancy is an important risk factor for cesarean delivery, especially among women aged less than 35 year.
en
dc.description.provenanceMade available in DSpace on 2021-06-13T04:18:20Z (GMT). No. of bitstreams: 1
ntu-95-R92846017-1.pdf: 543411 bytes, checksum: a14045d3586fa713ab4c83efe5c10751 (MD5)
Previous issue date: 2006
en
dc.description.tableofcontentsContents
Abstract in Chinese 3
Abstract 4
Chapter 1. Background 5
Chapter 2. Literatures review 8
1. Gestational weight gain and cesarean delivery 8
2. Proportional weight gain and cesarean delivery 11
3. Pre-pregnancy body mass index and cesarean delivery 12
4. Change of body mass index during pregnancy and cesarean delivery 17
Chapter 3. Framework, hypothesis, purpose of the study 29
Chapter 4. Materials and methods 31
1. Setting 31
2. Study period 31
3. Subjects 31
4. Information source and collection 32
5. Exposure and outcome 32
6. Statistical analysis 34
Chapter 5. Results 36
1. Demographic data 36
2. Analyses of risk factors for cesarean delivery 47
a. Univariate analysis 47
b. Multivariate analysis 51
Chapter 6. Discussions 61
1. Gestational weight gain and cesarean delivery 61
2. Proportional weight gain and cesarean delivery 63
3. Pre-pregnancy body mass index and cesarean delivery 64
4. Change of body mass index during pregnancy and cesarean delivery 65
5. Limitations of the study 67
6. Strengths of the study 69
Chapter 7. Conclusion 71
References 72


Table 1 Retrospective studies of gestational weight gain and cesarean delivery 18
Table 2 Prospective study of proportional weight gain and cesarean delivery 21
Table 3 Prospective studies of pre-pregnancy body mass index and cesarean delivery 22
Table 4 Retrospective studies of pre-pregnancy body mass index and cesarean delivery 24
Table 5 Prospective study of change of body mass index during pregnancy and cesarean delivery 28
Table 6 Indications for cesarean sections of all deliveries 38
Table 7 Demographic characteristics of all deliveries 40
Table 8 BMI classification of all deliveries (IOM criteria) 41
Table 9 BMI classification of all deliveries (DOH, Taiwan criteria) 41
Table 10 Demographic characteristics of study subjects 44
Table 11 Univariate analysis of risk factors for cesarean delivery (1) 48
Table 12 Univariate analysis of risk factors for cesarean delivery (2) 50
Table 13 -2LL value of gestational weight gain model 52
Table 14 -2LL value of pre-pregnancy BMI model 54
Table 15 -2LL value of change of BMI during pregnancy model 57
Table 16 Multivariate analysis of risk factors for cesarean delivery (1) 59
Table 17 Multivariate analysis of risk factors for cesarean delivery (2) 60
Table 18 Comparison with Kabiru et al.’s study 67

Fig. 1 Framework of the study 30
Fig. 2 Flow chart of the study 36
Fig. 3 Distribution of gestational weight gain 45
Fig. 4 Distribution of pre-pregnancy BMI 45
Fig. 5 Distribution of change of BMI during pregnancy 46
Fig. 6 Distribution of proportional weight gain 46
Fig. 7 ROC curve of gestational weight gain model 53
Fig. 8 ROC curve of pre-pregnancy BMI model 56
Fig. 9 ROC curve of change of BMI during pregnancy model 58
dc.language.isoen
dc.subject剖腹生產zh_TW
dc.subject身體質量指數zh_TW
dc.subjectbody mass indexen
dc.subjectcesarean deliveryen
dc.title懷孕期間身體質量指數變化與初次非計畫性剖腹生產風險之相關性研究zh_TW
dc.titleIs change of body mass index during pregnancy associated with the risk of primary unplanned cesarean delivery?en
dc.typeThesis
dc.date.schoolyear94-2
dc.description.degree碩士
dc.contributor.oralexamcommittee陳秀熙,季瑋珠
dc.subject.keyword身體質量指數,剖腹生產,zh_TW
dc.subject.keywordbody mass index,cesarean delivery,en
dc.relation.page76
dc.rights.note有償授權
dc.date.accepted2006-07-25
dc.contributor.author-college公共衛生學院zh_TW
dc.contributor.author-dept預防醫學研究所zh_TW
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