請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/30740
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 蕭浩明 | |
dc.contributor.author | Hung-Ta Wang | en |
dc.contributor.author | 王宏達 | zh_TW |
dc.date.accessioned | 2021-06-13T02:14:06Z | - |
dc.date.available | 2016-08-22 | |
dc.date.copyright | 2011-08-22 | |
dc.date.issued | 2011 | |
dc.date.submitted | 2011-08-20 | |
dc.identifier.citation | 1. C. Dumoulin, B. Cochelin, Mechanical Behavior modeling of Balloon-expandable Stents, Journal of Biomechanics, 2000. 33:p. 1461-1470.
2. T.W. Duerig, M. Wholey, A Comparison of Balloon- and Self-expanding Stents, Min Invas Ther & Allied Technol, 2002. 11(4):p. 173-178. 3. J. F. Dyet, W. G. Watts, D. F. Ettles, A. A. Nicholson, Mechanical Properties of Metallic Stents:How Do These Properties Influence the Choice of Stent for Specific Lesions?, Cardiovascular and Interventional Radiology, 2000. 23:p.47-54. 4. C. Kleinstreuer, Z Li, C.A. Basciano, S. Seelecke, M.A. Farber, Computational Mechanics of Nitinol Stent Grafts, Journal of Biomechanics, 2008. 41:p. 2370-2378. 5. C.T. Mendonca, R.C.R. Moreira, C.A. Carvalho, B.A. Moreira, J. Weingartner, A.Y. Shiomi, Endovascular Treatment of Abdominal Aortic Aneurysms in High-surgical-risk Patients, Journal Vascular Brasileiro, 2009. 8(1):p. 56-64. 6. H.M. Hsiao, A. Nikanorov, S. Prabhu, M.K. Razavi, Respiration-induced Kidney Motion on Cobalt-chromium Stent Fatigue Resistance, Journal of Biomechanical Materials Research, 2009. 91(2):p. 508-516. 7. K. Rocha-Singh, M.R. Jaff, K. Rosenfield, Evaluation of the Safety and Effectiveness of Renal Artery Stenting after Unsuccessful Balloon Angioplasty, Journal of the American College of Cardiology, 2005. 46(5):p. 776-783. 8. T. Zeller, U. Frank, C. Muller, K. Burgelin, L. Sinn, H. Bestehorn, N. Cook-Bruns, F. Neumann, Predictor of Improved Renal Function after Percutaneous Stent-supported Angioplasty of Severe Atherosclerotic Ostial Renal Artery Stenosis, Circulation, 2003. 108:p. 2244-2249. 9. C. J. Egelhoff, R.S. Budwig, D. F. Elger, T. A. Khraishi, K. H. Johansen, Model Studies of The Flow in Abdominal Aortic Aneurysms During Resting and Exercise Conditions, Journal of Biomechanics, 1999. 32:p.1319-1329. 10. J.J. Hosni, C.G. Vinagre, C. Mady, R.C. Maranhao, Lipolysis of Emulsion Models of Triglyceride-rich Lipoproteins is Altered in Male Patients with Abdominal Aorta Aneurysm, Jornal Vascular Brasileiro, 2007. 40:p. 305-307. 11. D. A. Vorp, Biomechanics of Abdominal Aortic Aneurysm, Journal of Biomechanics,2007. 40:p.1887-1902. 12. C. J. Egelhoff, R. S. Budwig, D. F. Elger, T. A. Khraishi, K. H. Johansen, Model Studies of the Flow in Abdominal Aortic Aneurysms, Journal of Biomechanics, 1999. 32:p.1319-1329. 13. C. Guivier-Curien, V. Deplano, E. Bertrand, J.D. Singland, F. Koskas, Analysis of Blood Flow Behaviour in Custom Stent Grafts, Journal of Biomechanics, 2009. 42:p. 1754-1761. 14. Z. Li, C. Kleinstreuer, Analysis of Biomechanical Factors Affecting Stent-graft Migration in an Abdominal Aortic Aneurysm Model, Journal of Biomechanics, 2006. 39:p. 2264-2273. 15. J.W. Hinnen, D.J. Rixen, O.H.J. Koning, J.H. Bockel, J.F. Hamming, Development of Fibrinous Thrombus Analogue for In-vitro Abdominal Aortic Aneurysm Studies, Journal of Biomechanics, 2007. 40:p. 289-295. 16. C.K. Chong, T.V. How, Flow Patterns in an Endovascular Stent-graft for Abdominal Aortic Aneurysm Repair, Journal of Biomechanics, 2004. 37:p. 89-97. 17. Z. Li, C. Kleinstreuer, Computational Analysis of Type II Endoleaks in a Stented Abdominal Aortic Aneurysms Model, Journal of Biomechanics, 2006. 39(14):p. 2573-2582. 18. L. Morris, P. Delassus, M. Walsh, T. McGloughlin, A Mathematical Model to Predict the in Vivo Pulsatile Drag Forces Acting on Bifurcated Stent Grafts Used in Endovascular Treatment of Abdominal Aortic Aneurysms (AAA),Journal of Biomechanics, 2004. 37:p. 1087-1095. 19. W. Q. Wang, D. K. Liang, D. Z. Yang, M. Qi, Analysis of The Transient Expansion Behavior and Design Optimization of Coronary Stents by Finite Element Method, Journal of Biomechanics, 2006. 39:p.21-32. 20. M. D. Beule, P. Mortier, S. G. Carlier, B. Verhegghe, R. V. Impe, P. Verdonck, Realistic Finite Element-Based Stent Design:The Impact of Balloon Folding, 2008.41:p.383-389. 21. C. M. Nickson, P. J. Doherty, R. L. Williams, Novel Polymeric Coatings with Potential to Control In-stent Restenosis – An In Vitro Study, Journal of Biomaterials Applications, 2010. 24(5):p. 437-452. 22. M. Zilberman, Y. Shifrovitch, M. Aviv, M. Hershkovitz, Structured Drug-eluting Bioresorbable Film:Microstructure and Release Profile Journal of Biomaterials Applications, 2009. 23(5):p. 385-406. 23. A. William, K. Navin, M. D. Kapur, Drug Eluting Stent Technology:A Paradigm Shift in the Treatment and Prevention of Restenosis, Journal of Pharmacy Practice, 2005. 18(6):p. 461-478. 24. D. Silvestri, C. Cristallini, M. Gagliardi, N. Barbani, M. D’Acunto, G. Ciardelli, P. Giusti, Acrylic Copolymers as Candidates for Drug-Eluting Coating of Vascular Stents, Journal of Biomaterials Applications, 2009. 24(4):p. 353-383. 25. R. A. Lookstein, A. D. Talenfeld, R. Raju, D. A. Vorchheimer, J. W. Olin, M. L. Marin, Sirolimus-eluting Stent Placement for Refractory Renal Artery In-stent Restenosis:Sustained Patency and Clinical Benefit at 24 Months,Vascular Medicine,2009. 14(4):p. 361-364. 26. G. Vairo, M. Cioffi, R. Cottone, G. Dubini, F. Migliavacca, Drug Release from Coronary Eluting Stents:A Multidomain Approach, Journal of Biomechanics, 2010. 43:p. 1580-1589. 27. S. W. Robertson, R. O. Ritchie, In Vitro Fatigue-crack Growth and Fracture Toughness Behavior of Thin-walled Superelastic Nitinol Tube for Endovascular Stents:A Basis for Defining the effect of Crack-like Defects,Biomaterials,2007. 28:p. 700-709. 28. M. Wagner, T. Sawaguchi, G. Kaustrater, D. Hoffken, G. Eggler, Structural Fatigue of Pseudoelastic NiTi Shape Memory Wires, Material Science and Engineering:A-elsevier, 2004. 378:p. 105-109. 29. R.V. Marrey, R. Burgermeister, R.B. Grishaber, R.O. Ritchie, Fatigue and Life Prediction for Cobalt-chromium Stents:A Fracture Mechanics Analysis, Biomaterials, 2000. 27:p. 1988-2000. 30. N. Bessias, G. Sfyroeras, K.G. Moulakakis, Renal Artery Thrombosis Caused by Stent Fracture in a Single Kidney Patient, Journal Endovascular Therapy, 2005. 12:p. 516-520. 31. S. Sahin, A. Memis, M. Parildar, I. Oran, Facture of a Renal Artery Stent Due to Mobile Kidney, Cardiovasc Intervent Radiol, 2005. 28:p. 683-685. 32. H.M. Hsiao, S. Prabhu, A. Nikanorov, M. Razavi, Renal Artery Stent Bending Fatigue Analysis, Journal of Medical Devices, 2007. 1:p. 113-118. 33. FDA data, Available from:http://www.fda.gov/. 34. E. W. Donnelly, M. S. Bruzzi, T. Connolley, P. E. Mchugh, Finite Element Comparison of Performance Related Characteristics of Balloon Expandable Stents, Computer Methods in Biomechanics and Biomedical Engineering, 2007. 10(2):p. 103-110. 35. H. Zahedmanesh, D. J. Kelly, C. Lally, Simulation of a Balloon Expandable Stent in a Realistic Coronary Artery-Determination of the Optimum Modeling Strategy, Journal of Biomechanics,2010. 43(11):p. 2126-2132. 36. W. W. O’Neill, M. B. Leon, Drug-eluting Stents:Cost Versus Clinical Bene, Circulation, 2003. 107:p. 3008-3011. 37. C. Kleinstreuer, Z. Li, C. A. Basciano, S. Seelecke, M. A. Farber, Computational Mechanics of Nitinol Stent Grafts, Journal of Biomechanics, 2008. 37:p.2370-2378. 38. L. Petrini, F. Migliavacca, F. Auricchio, G. Dubini, Numerical Investigation of the Intravascular Coronary Stent Flexibility, Journal of Biomechanics, 2004. 37:p.495-501. 39. W. Wu, W. Q. Wang, D. Z. Yang, M. Qi, Stent Expansion in Curved Vessel and Their Interactions:A Finite Element Analysis, Journal of Biomechanics, 2007. 40:p.2580-2585. 40. P.W. Serruys, J. A. Ormston, Y. Onuma, E. Regar, N. Gonzalo, H. M. Garcia-Garcia, K. Nieman, N. Bruining, C. Dorange, K. Miquel-Hebert, S. Veldhof, M. Webster, L. Thuesen, D. Dudek, A Bioabsorbable Everolimus-eluting Coronary Stent System(ABSORB):2-year Outcomes and Results from Multiple Imaging Methods, Lancet, 2009. 14:p.897-910. 41. C. Zhang, N. Zhang, X. Wen, Improving the Elasticity and Cytophilicity of Biodegradable Polyurethane by Changing Chain Extender, Journal of Biomedical Materials Research, 2006. 79B:p. 335-344. 42. S.I. Ertel, J. Kohn, Evaluation of a Series of Tyrosine-Derived Polycarbonates as Degradable Biomaterial, Journal of Biomedical Materials Research, 1994. 28(8):p.919-930. 43. T. Xi, R. Gao, B. Xu, L. Chen, T. Luo, J. Liu, Y. Wei, S. Zhong, In Vitro and in Vivo Changes to PLGA/Sirolimus Coating on Drug Eluting Stents, Journal of Biomaterials, 2010. 31:p. 5151-5158. 44. J.H. Kim, T. J. Kang, W.R. Yu, Mechanical Modeling of Self-expandable Stent Fabricated Using Braiding Technology, Journal of Biomechanics, 2008. 41:p.3202-3212. 45. L. Petrini, F. Migliavacca, F. Auricchio, G. Dubini, Numerical Investigation of the Intravascular Coronary Stent Flexibility, Journal of Biomechanics, 2004. 37:p. 495-501. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/30740 | - |
dc.description.abstract | 血管支架應用於治療冠狀動脈窄化成果顯著,使其已成為治療心血管疾病的黃金標準,並廣泛應用於人體其他周邊血管,因此血管支架具備雄厚的成長潛力。以往血管支架研製流程為傳統設計、製成加工、性能測試,由於傳統設計方法十分費時,無法針對測試結果做有效率的修改,為了改善血管支架研製效率,本研究將參數化設計概念(Parametric Design)和有限元素法(Finite Element Method)加入血管支架的研製流程,使研製流程更加有效率,其中有限元素分析用於預測支架性能測試的結果,而經由參數化設計的支架,可針對有限元素分析結果快速的修改局部設計參數,在參數化設計和有限元素法相輔相成的作用下,使血管支架研製效率大幅提升,且降低研發成本。本論文並將參數化設計支架之局部參數做微調,且透過有限元素分析測試其性能的改變,並以圖表方式呈現各式設計參數與支架性能的對應關係,再次驗證參數化設計概念與有限元素法對支架研製流程的重要性。
關鍵字:氣球擴張式血管支架、參數化設計、有限元素分析 | zh_TW |
dc.description.abstract | Due to the significant achievement of curing coronary narrowing, stents are widely applied to the other wounded parts of human body or specific medical purposes. Therefore, stents have got abundant developing potential. Stents’ conventional development process is: traditional design, manufacture of processing, performance testing, and FDA certification. Because traditional design method takes much time and can not efficiently do the modification according to the test results, to improve the efficiency of stent development, this research puts parametric design and finite element method into the development process so that the stents’ development process now changes as follows: parametric design, finite element simulation analysis, manufacture of processing, performance testing, and FDA certification. Finite element analysis is used to predict the results of performance testing. And the local design parameters of parametric design stents can be quickly modified according to the test result by finite element analysis. The cooperating between parametric design and finite element method significantly increases the efficiency of stent development and reduces its costs as well. In chapter 5 of this thesis, the local parameters of parametric design stent have been fine -tuned, through finite element analysis, the test of performance changes has been done, and the graph shows the corresponding relationship between various design parameters and stent performance. All of these have once again proven that parametric design and finite element method are important for stent development process.
Keywords : Balloon-Expandable Stent、Parametric Design、Finite Element Analysis | en |
dc.description.provenance | Made available in DSpace on 2021-06-13T02:14:06Z (GMT). No. of bitstreams: 1 ntu-100-R98522838-1.pdf: 3254635 bytes, checksum: 434986df0a2ef265b1647fe0ac4460ea (MD5) Previous issue date: 2011 | en |
dc.description.tableofcontents | 致謝 I
中文摘要 II 英文摘要 III 目錄 IV 圖目錄 VI 表目錄 XI 第一章 緒論 1 1. 1 前言 1 1. 2 研究動機 4 1. 3 論文架構 5 第二章 文獻回顧 6 第三章 血管支架參數化設計 11 3. 1支架局部專有名詞介紹 12 3. 2支架局部參數化定義 13 3. 3支架整體架構參數化義 14 3. 4參數限制與參數連動方程式 15 3. 5支架實體模型建立 16 第四章有限元素法模型建立 17 4.1邊界條件與剛體運動 19 4.2壓縮與擴張測試 21 4.3疲勞測試 27 第五章支架局部參數調校 32 5.1網格收斂分析 32 5.2 Crown Radius參數調校 33 5.3 Strut Thickness參數調校 38 5.4 Strut Width參數調校 43 5.5 Strut Length參數調校 47 5.6綜合比較 52 第六章 結論 53 參考文獻 54 | |
dc.language.iso | zh-TW | |
dc.title | 氣球擴張式血管支架參數化設計與模擬 | zh_TW |
dc.title | Parametric Design and Simulation of Balloon-Expandable Stents | en |
dc.type | Thesis | |
dc.date.schoolyear | 99-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 李貫銘,廖英志 | |
dc.subject.keyword | 氣球擴張式血管支架,參數化設計,有限元素分析, | zh_TW |
dc.subject.keyword | Balloon-Expandable Stent,Parametric Design,Finite Element Analysis, | en |
dc.relation.page | 59 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2011-08-21 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
顯示於系所單位: | 機械工程學系 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-100-1.pdf 目前未授權公開取用 | 3.18 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。