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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/28942完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 蘇侃 | |
| dc.contributor.author | Hong-Da Lu | en |
| dc.contributor.author | 盧弘達 | zh_TW |
| dc.date.accessioned | 2021-06-13T00:30:46Z | - |
| dc.date.available | 2007-07-31 | |
| dc.date.copyright | 2007-07-31 | |
| dc.date.issued | 2007 | |
| dc.date.submitted | 2007-07-26 | |
| dc.identifier.citation | 1.GB Andersson, “The epidemiology of spinal disorders,” In Frymoyer JW (ed). The Adult Spine: Principles and Practice. Ed 2. Philadelphia, Lippincott-Raven, 93–141, 1997
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Bonar, “Three-dimensional movements of the whole lumbar spine and lumbosacral joint,” Spine, 14（11）, 1256-1260, 1989 18.CR Bragdon, BS, D 0 O’Connor, AS, JD Lowenstein, M Jasty, MD and WD Syniuta, ScD, “The importance of multidirectional motion on the wear of polyethylene,” Proc Iostn Mcch Engrs , 210, 157-165, 1996 19.HA Serhan, PhD, AP Dooris, PhD, ML Parsons, MS, PJ Ares, and SM Gabriel, PhD, PE, “In Vitro Wear Assessment of the Charite´ Artificial DiscAccording to ASTM Recommendations,” SPINE , 31（17）, 1900–1910, 2006 20.American Society of Testing and Materials International, “Standard Test Method for Wear Testing of Polymeric Materials Used in Total Joint Prostheses1,” F 732 – 00, 2006. 21.American Society of Testing and Materials International, “Standard Guide for Functional, Kinematic, and Wear Assessment of Total Disc Prostheses1,” F 2423 – 05, 2006. 22.American Society of Testing and Materials International, “Standard Specification for Ultra-High-Molecular Weight Polyethylene Powder and Fabricated Form for Surgical Implants,”F 648 – 04, 2004 23.American Society of Testing and Materials International, “Standard Specification for Polyetheretherketone (PEEK) Polymers for Surgical Implant Applications,”F 2026 – 02, 2002 24.American Society of Testing and Materials International, “Standard Specification for Cobalt-28 Chromium-6 Molybdenum Alloy Castings and Casting Alloy for Surgical Implants (UNS R30075),” F 75 – 07, 2007. 25.CH Rivard, S Rhalmi, C Coillard, “In vivo biocompatibility testing of peek polymer for a spinal implant system: A study in rabbits,” Pediatric Research Center, Sainte-Justine Hospital, Montreal, Canada, 488-498, 2002 26.GI Howling, H Sakoda, A. 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Kurtz, PhD, J Peloza, MD, R Siskeya, ML Villarraga, PhD, “Analysis of a retrieved polyethylene total disc replacement component,” The Spine Journal, 5, 344–350, 2005 29.T David, “, Revision of a Charite´ artificial disc 9.5 years in vivo to a new Charite´ artificial disc: case report and explant analysis”, Eur Spine J, 14, 507–511, 2005 30.HH Matthews, L Eisermann, JC LeHuec, et al., “An in-vitro biomechanical evaluation of the wear behavior of Maverick Total Disc Replacement,” 10th International Meeting on Advanced Spine Techniques, Rome, 2003 , 8 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/28942 | - |
| dc.description.abstract | 本研究針對人工椎間盤進行磨耗實驗；以一台自行設計的人工椎間盤磨秏試驗機進行。本實驗設定椎間盤以屈曲-伸展14°、側向彎曲±7°以及扭轉±2.5°的運動模式，施加1500±50N的負載，並且將人工椎間盤浸泡於稀釋至25％的血清溶液內，在3Hz的運動頻率下觀察每50萬週期的厚度與重量減少量、試片表面情形並且收集磨屑，持續至250萬週期。
由實驗結果得知，以聚芳醚酮作為核心材料的人工椎間盤在磨耗與變形上比以超高分子量聚乙烯作為核心之人工椎間盤有較好的表現。且實驗結果顯示因半橢圓球面設計而導致接觸面積不足與運動過程有非順應接觸的缺失。此外，加工上精度的要求與表面粗糙度也嚴重影響實驗的結果。 下一階段的人工椎間盤將以半球形面取代半橢圓球面設計，並且需提出加工製造與拋光處理流程，要求表面粗糙度達到 ＝0.05μm以下，使表面間有較平順的接觸行為。 未來可以將人工椎間盤植入動物體內，觀察替代物附近的細胞組織是否有發炎或其他不良反應。 | zh_TW |
| dc.description.abstract | The wear behavior of the artificial intervertebral discs designed in the present work was studied. An intervertebral disc simulator was designed and constructed for performing the experiment. This simulator allows the tested disc make the flexion-extension of 14°, lateral bending of ±7° and rotation of ±2.5° under a cyclic frequency of 3 Hz, exerts a load up to 1500±50N. During a test, the artificial intervertebral disc was soaked in a 25% blood serum solution. The thickness and the weight decrement of the disc were measured and the wear debris was exammed in every five-hundred thousand cycle operation.
From the experimental results we find that, using PEEK as the core material of the artificial intervertebral disc is better in the abrasion and the distortion than using UHMWPE. The experimental results also show that the semi-ellipsoidal surface design causes the contact area to wear severely when combined bending and rotating motion took place. In addition, the precision in processes and the surface roughness of the metallic parts were responsible for core wear. The semi-ellipsoidal surface will be replaced by a hemispheroidal surface in the next device design. The required surface roughness of the metallic parts should be as low as ＝0.05μm. In the future, we will try to implant the artificial intervertebral disc into suitable animals in vivo, and observe cellulary tissues nearby the substitute whether will have the inflammation or other bad situation happen. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-13T00:30:46Z (GMT). No. of bitstreams: 1 ntu-96-R94522527-1.pdf: 3605431 bytes, checksum: f43fc5c0ec03692b7a79a9aa42f5f9d3 (MD5) Previous issue date: 2007 | en |
| dc.description.tableofcontents | 摘要 …………………………………………………………Ⅰ
Abstract ……………………………………………………Ⅱ 目錄 …………………………………………………………Ⅳ 圖目錄 ………………………………………………………Ⅵ 表目錄 ………………………………………………………Ⅹ 第一章 緒論 1-1 簡介 ……………………………………………………1 1-2 椎間盤之簡介 …………………………………………2 1-3 人工椎間盤之簡介…………………………………… 5 1-3-1 SB Charitè……………………………………………5 1-3-2 Prodisc……………………………………………… 7 1-3-3 AcroFlex …………………………………………… 7 1-3-4 Maverick………………………………………………8 1-3-5 FlexiCore…………………………………………… 8 1-3-6 Prosthetic Disc-Nucleus………………………… 9 1-4 文獻回顧………………………………………………10 1-4-1 人工椎間盤相關文獻回顧…………………………10 1-4-2 實驗方法相關文獻回顧……………………………11 第二章 磨潤理論 2-1 關節潤滑機制…………………………………………13 2-2 表面型態定義…………………………………………13 2-3 潤滑模式與界定………………………………………14 2-3-1 液動潤滑 ………………………………………… 15 2-3-2 彈液動潤滑…………………………………………16 2-3-3 混合潤滑……………………………………………17 2-3-4 邊界潤滑……………………………………………17 2-4 表面膜與邊界膜………………………………………18 2-5 邊界潤滑下的磨耗現象………………………………18 第三章 研究方法 3-1 磨耗試驗機之設計 ………………………………… 20 3-2 實驗環境 …………………………………………… 24 3-3 實驗步驟與結果量測 ……………………………… 25 3-3-1 試片準備…………………………………………… 25 3-3-2 實驗步驟…………………………………………… 29 3-3-3 量測準則…………………………………………… 30 第四章 實驗結果與討論 4-1 屈曲-伸展與扭轉同時進行下之磨耗結果………… 32 4-2 屈曲-伸展時之磨耗結果…………………………… 36 4-3 側向彎曲與扭轉同時進行下之磨耗結果 ………… 40 4-4 依據不同核心材料進行討論 ……………………… 46 4-5 依據不同運動模式進行討論 ……………………… 50 4-6 綜合討論 …………………………………………… 52 第五章 結論與未來研究方向 5-1 結論……………………………………………………56 5-2 未來研究方向…………………………………………56 參考文獻…………………………………………………… 58 | |
| dc.language.iso | zh-TW | |
| dc.subject | 人工椎間盤 | zh_TW |
| dc.subject | 磨耗 | zh_TW |
| dc.subject | 聚芳醚酮 | zh_TW |
| dc.subject | 超高分子量聚乙烯 | zh_TW |
| dc.subject | PEEK | en |
| dc.subject | UHMWPE | en |
| dc.subject | artificial intervertebral discs | en |
| dc.subject | wear | en |
| dc.title | 人工椎間盤之磨耗分析 | zh_TW |
| dc.title | Wear Analysis of Artificial Intervertebral Disc | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 95-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳博光,吳興盛 | |
| dc.subject.keyword | 磨耗,人工椎間盤,聚芳醚酮,超高分子量聚乙烯, | zh_TW |
| dc.subject.keyword | wear,artificial intervertebral discs,PEEK,UHMWPE, | en |
| dc.relation.page | 62 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2007-07-26 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
| 顯示於系所單位： | 機械工程學系 | |
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