分子夾雙聚體之合成研究

Abstract

本實驗室在先前的報導中已經成功地合成了具有TTF側臂的分子夾，並以其與一個具有18C6冠醚與帶有缺電子性質的pyridinium系統之大環分子結合成一個可受四種方法(離子、酸鹼、溫度、氧化還原)控制的分子開關。為了延伸此分子夾系統的應用性，我們在此分子夾系統底部苯環的對位導入一個pyridine取代基，希望利用pyridine與金屬配位的特性，期望可利用金屬將分子夾製備成雙聚體。

We have reported the synthesis of a molecular clip with TTF (tetrathiafuvalene) as the sidewalls and its binding behavior towards a macrocycle in which an electron-deficient pyridinium unit was present. This macrocycle/molecular-clip complex functions as a quadruply controllable molecular switch for the addition and removal of heat, metal ions, protons, electrons. To extend the application of this molecular clip system, we plan to synthesize new molecular clips that present suitable functionalities as their “feet” which are capable to connect with metal. These molecular clip dimer could creat a new host-guest system compared to the traditional rotaxane and catenane.