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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 張睿詒 | |
| dc.contributor.author | Yu-Chun Hsieh | en |
| dc.contributor.author | 謝郁君 | zh_TW |
| dc.date.accessioned | 2021-06-08T07:01:06Z | - |
| dc.date.copyright | 2009-09-16 | |
| dc.date.issued | 2009 | |
| dc.date.submitted | 2009-05-11 | |
| dc.identifier.citation | 參考文獻
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/26136 | - |
| dc.description.abstract | 研究背景
左心室向心性再塑型化為較初期之心臟血管疾病表徵，其會提高心臟血管疾病的罹病風險、死亡風險，但國內探討左心室向心性再塑型化相關危險因子之研究顯少。 研究目的 本研究欲探討在一般民眾中左心室向心性再塑型化相關危險因子，期提供更多資訊協助臨床醫護人員、公共衛生相關人員在心臟血管疾病預防保健、治療照護工作上，一方面達到減少國人心臟血管疾病罹病率、提升國人健康及生活品質，另一方面期能降低其罹患心臟血管疾病後所帶來的龐大醫療費用。 研究方法 本研究選取台北市某醫學中心之健康檢查中心自2005年10月1日至2008年11月30日止同時進行理學檢查、空腹血糖檢驗、總膽固醇檢驗、三酸甘油脂檢驗、高密度脂蛋白膽固醇檢驗、低密度脂蛋白膽固醇檢驗、高敏感性C反應蛋白檢驗、高半胱胺酸檢驗、原生B型利鈉胜肽檢驗、心臟超音波檢查的民眾共1265位為研究對象，並利用其當次健康檢查資料進行分析研究。 研究結果 綜合研究結果發現，總膽固醇濃度、低密度脂蛋白膽固醇濃度、高敏感性C反應蛋白濃度、高半胱胺酸濃度、原生B型利鈉胜肽濃度、代謝症候群皆為左心室向心性再塑型化之獨立危險因子，而其會增加1.5~2.5倍的左心室向心性再塑型化罹病風險。 結論 期此研究結果對於臨床醫療人員在評估民眾罹患左心室向心性再塑型化有所助益以早日介入治療，進而提升國人健康、降低罹患心臟血管疾病之風險，以及減少心臟血管疾病相關醫療費用。 | zh_TW |
| dc.description.abstract | Background
Left ventricular concentric remodeling is a condition of the early cardiovascular disease, and it is associated with markedly increased risk for cardiovascular disease morbidity and mortality. However, the study about exploring the risk factors for left ventricular concentric remodeling in general population was not well established. Objective The aim of the present study is to evaluate the independent risk factors for left ventricular concentric remodeling in general population and expect to provide more information and welfare for prevention, control, treatment and healthcare of cardiovascular disease. Besides to reduce cardiovascular disease morbidity and enhance the health and quality of life of citizens, on the other hand hope to reduce the huge medical expenses for cardiovascular disease. Methods In this study, 1265 consecutive subjects were enrolled in a Health Evaluation Center-based population study (since October 1, 2005 to November 30, 2008). Data including baseline characteristics, physical examination, total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-sensitivity C-reactive protein (hs-CRP), homocysteine, N-terminal prohormone brain natriuretic peptide (NT-proBNP), echocardiography were all collected and evaluated. Results In this study found that total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-sensitivity C-reactive protein (hs-CRP), homocysteine, N-terminal prohormone brain natriuretic peptide (NT-proBNP), and metabolic syndrome (MS) were the independent risk factors for left ventricular concentric remodeling in general population. And people with un-normal total cholesterol, low-density lipoprotein cholesterol, high-sensitivity C-reactive protein, homocysteine, N-terminal prohormone brain natriuretic peptide, and people with metabolic syndrome had 1.5-fold to 2.5-fold increased risk for morbidity of cardiovascular disease. Conclusions Look forward to the results of this study for clinical assessment of people suffering in left ventricular concentric remodeling of the early intervention help the treatment to enhance the health of people, reduce risk for morbidity of cardiovascular disease and the medical expenses causing of cardiovascular disease. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-08T07:01:06Z (GMT). No. of bitstreams: 1 ntu-98-R95843012-1.pdf: 341265 bytes, checksum: 40f88cf23cc9375945ebef7116618292 (MD5) Previous issue date: 2009 | en |
| dc.description.tableofcontents | 目錄
誌謝 I 摘要 II Abstract III 目錄 V 圖目錄 VI 表目錄 VII 第一章 緒論 1 第一節 研究背景與動機 1 第二節 研究目的 3 第二章 文獻探討 4 第一節 心臟血管疾病介紹 4 第二節 左心室向心性再塑型化介紹 9 第三節 代謝症候群介紹 10 第四節 心臟血管疾病相關生化檢驗指標介紹 18 第三章 研究材料與方法 21 第一節 研究設計與架構 21 第二節 研究變項之定義 23 第三節 資料處理與分析 24 第四章 研究結果 27 第一節 描述性統計分析 27 第二節 推論性統計分析 29 第五章 討論與結論 33 第一節 研究結果討論 33 第二節 研究限制 36 第三節 結論與建議 36 參考文獻 38 中文部分 38 英文部分 39 附錄一 45 圖目錄 圖1-1-1 門、住診（包括急診）醫療費用統計 3 圖3-1-1 研究架構 23 表目錄 表2-2-1 代謝症候群定義 12 表2-2-2 IDF 2005對各國家腰圍定義 14 表4-1-1 描述性統計分析結果(1) 28 表4-1-2 描述性統計分析結果(2) 28 表4-2-1 推論性統計分析結果(1) 29 表4-2-2 推論性統計分析結果(2) 30 表4-2-3 羅吉斯迴歸分析結果 32 | |
| dc.language.iso | zh-TW | |
| dc.subject | 代謝症候群 | zh_TW |
| dc.subject | 左心室向心性再塑型化 | zh_TW |
| dc.subject | 心臟血管疾病 | zh_TW |
| dc.subject | 生化檢驗指標 | zh_TW |
| dc.subject | Cardiovascular disease | en |
| dc.subject | Metabolic syndrome | en |
| dc.subject | Biomarker | en |
| dc.subject | Concentric left ventricular remodeling | en |
| dc.title | 左心室向心性再塑型化與心血管疾病檢驗指標及代謝症候群之相關性研究 | zh_TW |
| dc.title | A Study on the Association of Left Ventricular Concentric Remodeling with the Biomarkers of Cardiovascular Disease and Metabolic Syndrome | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 97-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳進堂,吳彬安 | |
| dc.subject.keyword | 左心室向心性再塑型化,心臟血管疾病,生化檢驗指標,代謝症候群, | zh_TW |
| dc.subject.keyword | Concentric left ventricular remodeling,Cardiovascular disease,Biomarker,Metabolic syndrome, | en |
| dc.relation.page | 49 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2009-05-12 | |
| dc.contributor.author-college | 公共衛生學院 | zh_TW |
| dc.contributor.author-dept | 醫療機構管理研究所 | zh_TW |
| 顯示於系所單位： | 健康政策與管理研究所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-98-1.pdf 未授權公開取用 | 333.27 kB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。