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  1. NTU Theses and Dissertations Repository
  2. 管理學院
  3. 國際企業學系
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/24707
完整後設資料紀錄
DC 欄位值語言
dc.contributor.advisor邱宏仁
dc.contributor.authorYu-Shan Suen
dc.contributor.author蘇友珊zh_TW
dc.date.accessioned2021-06-08T05:37:41Z-
dc.date.copyright2004-11-11
dc.date.issued2004
dc.date.submitted2004-11-05
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/24707-
dc.description.abstract在新興科技主導生物科技商務領域的時代,創新已經成為生物科技新創事業的主要競爭優勢。生物科技新創事業現已透過各種知識創造的機制來培植創新,諸如以生物資訊為基礎之高透析檢視之技術。
本研究之主要目的乃在探討創新的本質,特別是在以科學為基礎的生物科技產業。創新有兩種來源:內部來源受限於公司之現有能力之推展;外部來源則考慮於公司之外部夥伴關係。本研究整理了熊彼得學派與資源基礎學派來探討創新的內部來源;以及包含了資源依賴理論與社會網絡理論來探討創新的外部來源。
本研究嘗試從最小平方的迴歸方法(OLS)實證檢驗,能力發展與夥伴關係如何影響78家台灣生物科技新創事業之創新。再者,本研究也提出策略導向這個調和變數:分別調和創新與能力發展,與調和創新與夥伴關係之關係。並進一步以變異數分析(ANOVA)與Scheffe檢定,檢驗調和效果的關係。
研究結果顯示出生技事業之產品創新與製程創新都與其研發能力、行銷能力與大學研究機構之夥伴關係有顯著的正相關。特別是,研發能力發展完全中介了資源存量與兩類型創新之效果。然而,當本研究考慮生技事業之策略導向是否為技術導向時,研發能力與大學研究機構之夥伴關係兩者對於創新的直接效果都消失了。
相反地,行銷能力對於生技事業之創新同時有直接與調和的效應,而供應商關係則被策略導的調和效果來影響生技事業之創新。即是在其策略導向之導引下,以知識為基礎的生技事業應該更有效的推展其能力鑲嵌在密集的市場知識與整合供應鏈組合成密集的平台知識,更進一步的培植其創新績效。
zh_TW
dc.description.abstractAt the age when emerging technologies dominate biotech-commerce landscape, innovation has become the primary driver of competitive advantage for biotechnology ventures. Biotechnology ventures have cultivated their innovativeness through a variety of knowledge-creating mechanisms such as high-throughput screening techniques based on bioinformatics.
The main purpose of this study is to discuss the nature of innovation, especially in the science-based biotechnology industry. There are two sources of innovation. Internal source is constrained by a firm’s existing capability deployment. External source is considered by a firm’s partnering relations. In the present study, Schumpeterian economics and resource-based view are incorporated into the discussion of a firm’s internal path of innovation, while resource dependence theory and social network theory are adopted to examine a firm’s external path of innovation.
This research attempts to examine empirically how capability deployment and vertical partnership affect the innovativeness of 78 Taiwan-based biotechnology ventures. Moreover, it is proposed that a venture’s strategic orientation could moderate the relationships of innovativeness with capability deployment, and the relationships of innovativeness with vertical partnership. It analyzes by ordinary least square (OLS) approach. And, it also incorporates analysis of variance (ANOVA) and Scheffe’s test to examine the moderating effects in advance.
Results gathered from this study show that the venture’s both product- and process- innovativeness are both positively related to its R&D capability, marketing capability, and URI (universities and research institutions) partnership. In particular, R&D capability deployment can fully mediate the effects of resource stocks on both types of innovativeness. However, upon considering whether or not a venture’s strategic orientation is technology-driven, the direct effects of R&D capability and URI partnership on innovativeness disappear.
In contrast, a venture’s marketing capability has both direct and moderated effects on the innovativeness, while supplier relationship moderated by strategic orientation can also affect the innovativeness. In other words, guided by its strategic orientation, the knowledge-based venture should be more effective in deploying its capabilities embedded with extensive market knowledge, and in integrating its supply chains which composed of intensive platform knowledge. Accordingly, both marketing capability and supplier partnership can further cultivate its innovativeness.
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Previous issue date: 2004
en
dc.description.tableofcontentsList of Contents
List of Tables…..………………………..……………………………………V
List of Figures…….………………………………………………………VIII
CHAPTER 1 INTRODUCTION…………………………………………………………..1
1.1 Research Motivation…………………………………………………...1
1.2 Research Questions…………………………………………………….2
1.3 Research Scope…………………………………………………………3
CHAPTER 2CONTEXT OF BIOTECHNOLOGY INDUSTRY…………………….…4
2.1 Overview of Global Biotechnology Industry.…………………….4
2.2 Leading Role of USA in the Biotechnology Industry….………8
2.3 Overview of Biotechnology Industry in Taiwan……………….12
2.4 Features of Biotechnology Industry…..……………………..……...15
CHAPER 3 LITERATURE REVIEW………………………………………………….21
3.1 The Schumpeterian Firm…………………………………..…………21
3.1.1 Challenges to Schumpeter……………………………………….24
3.1.2 Type of Innovation…………...…………………………………..28
3.1.3 The process of Innovation………...……………………………..32
3.2 Resource-Based View of the Firm……………………………………36
3.2.1 Penrosian and Resource-Based view…...………………………36
3.2.2 Resource Combination and Innovation……………………..39
3.3 Resource Dependence Theory………………………………………..40
3.4 Social Network Theory……………………………………………….42
3.4.1 Social Networks………………………………...…...…………..42
3.4.2 Social Networks and New Ventures…………………...………46
3.5 Comparisons of Theories……………………….…………………50
RESEARCH HYPOTHESES………………..…………………………..55
3.6 The Internal Source of Innovation…………………………………..56
3.6.1 Firm Resources…...……………………………………………...56
3.6.2 Firm Capabilities….…..…………………………………………57
3.6.3 Firm Capabilities as a Mediator between Resources andInnovativeness………..…….……...………………………........59
3.7 The External Source of Innovation………………………………….60
3.7.1 Inter-firm Partnerships………………………………...……….60
3.8 Strategic Orientation as a Moderator……………………………….62
3.8.1 Strategic Orientation as a Moderator between Capability and Innovativeness……………………………...……………………63
3.8.2 Strategic Orientation as a Moderator between Partnership and Innovativeness…………….……..………………………………65
CHAPTER 4RESEARCH METHODS…………………………………………………...67
4.1 Data Collection and Sampling…..…………..……………………….67
4.2 Measures………………………………………………………………69
4.3 Statistical Analysis……...…………………………………………….71
4.3.1 Assessment of Instrument Validity and Reliability……......73
4.3.2 Testing the Normality………………………………………….75
4.3.3 Multicollinearity……………...………………………………....77
4.3.4 Heteroscedasticity……………....……………………………….78
4.3.5 Generalized Least Squares Analysis...………………………81
CHAPTER 5EMPIRICAL RESULTS…………………………………………………...92
5.1 Descriptive Statistics and Summary Results………………………...92
5.2 Tests of Hypotheses…….……………………………………………...92
5.3 Manipulation Checks…………………………………………………95
CHAPTER 6DISCUSSION AND CONCLUSIONS…………………………………107
6.1 Major Findings and Managerial Implications……………………107
6.2 Theoretical Implications…………………………...…………….…109
6.3 Directions of Future Research……….…………..…………………110
6.4 Research Limitations………………………………….……………110
REFERENCE…………………………………………....…………………112
APPENDIX……………………………..……………………………..……133
Appendix 1 Questionnaire…………………………...…………………133
Appendix 2 Regression Results after Adjusting Heteroscedasticity (by white t)……………………………139
Appendix 3 GLS Results……………...………………………………..143
Appendix 4 Nonlinear Direct Effects of Resource on Capability…………………………………………….…147
Appendix 5 Interview Results………………………………………....154

List of Tables
Table 2.1 2001 Global Biotechnology and Pharmaceutical Industry Profile………...……..……………………………………………..7
Table 2.2 Market Capitalization ….….……...……………………………..7
Table 2.3 2001 Global Biotechnology Market Structure (By Application)…………..……………………………………….8
Table 2.4 2001 Global Biotechnology Market Structure (By Region)…………………………..…………………………….8
Table 2.5 2001 USA Biotechnology Industry Statistics…………………..10
Table 2.6 1992-1998 Profitable Biotechnology Companies in USA……...11
Table 2.7 1989-1994 Distribution of Biotechnology Patents……………..11
Table 2.8 USA 2012 Estimated Biotechnology Industry Revenues……...12
Table 2.9 1998 Market Structures in Terms of Revenues of Taiwan Biotechnology Industry………………………………………...14
Table 2.10 2001 Taiwan Biotechnology Industry Revenues……………...15
Table 2.11 Summaries of Recent Researches in the Biotechnology Industry....……………………………………………..………18
Table 3.1 Australian School versus IO-based Economics………………..23
Table 3.2 Industrial Innovation in the Three Phases…………...…….….30
Table 3.3 Two Traditions of Research………………………………….….33
Table 3.4 Two Camps of Research………………………………………...34
Table 3.5 Comparison of different theoretical view on innovation……...54
Table 4.1 Characteristics of Sample……………………………………….84
Table 4.2 Definitions and expected signs of variables……………………85
Table 4.3 Question items…………………………………………………...86
Table 4.4 One Sample Kolmogorov-Sminov (K-S) Test………………….75
Table 4.5 Results of Factor Analysis………………...…………………….88
Table 5.1 Means, Standard Deviations, and Correlations………….……97
Table 5.2 Results of regression analysis 1 – Direct Effects on Capability………………………………………………………...98
Table 5.3 Results of regression analysis 2 - Direct Effects on Innovativeness…………………………………………………...99
Table 5.4 Results of regression analysis 3 - Mediating Effects on Innovativeness………………………………...……………..….100
Table 5.5 Results of regression analysis 4 - Interaction effects on Innovativeness…………...……………………………………...101
Table 5.6 Variations in product innovativeness by “marketing capability-strategic orientation” clusters…………………..…102
Table 5.7 Variations in product innovativeness by “marketing capability-strategic orientation” clusters……………………103
Table 5.8 Variations in product innovativeness by “manufacturing capability-strategic orientation” clusters………………....…104
Table 5.9 Variations in product innovativeness by “suppliers’ partnership-strategic orientation” clusters……………..…...105
Table 5.10 Variations in product innovativeness by “suppliers’ partnership-strategic orientation” clusters…..…………….106

List of Appendix Tables
Table a.2.1 Results of regression analysis 1 – Direct Effects on Capability…………………………………………………139
Table a.2.2 Results of regression analysis 2 – Direct Effects on Innovativeness……………………………………………140
Table a.2.3 Results of regression analysis 3 – Mediating Effects on Innovativeness……………………………………………141
Table a.2.4 Results of regression analysis 4 – Interaction Effects on Innovativeness……………………………………………142
Table a.3.1 Results of GLS analysis 1 – Direct Effects on Capability…………………………………………………143
Table a.3.2 Results of GLS analysis 2 – Direct Effects on Innovativeness……………………………………………144
Table a.3.3 Results of GLS analysis 3 – Mediating Effects on Innovativeness……………………………………………145
Table a.3.4 Results of GLS analysis 4 – Interaction Effects on Innovativeness……………………………………………146
Table a.4.1 Nonlinear Direct Resource Effects on Capability…...……..147
Table a.4.2 Nonlinear Mediating Effects on Innovativeness……….…..150

List of Figures
Figure 2.1 The Global Value Chain of the Biotechnology Industry………………6
Figure 3.1 A Typology of Product and Process Technological Change………….25
Figure 3.2 Architectural innovation……..……………...…………………………26
Figure 3.3 Theory of S-curve…………………………………...……………...…..27
Figure 3.4 The Dynamics of Innovation…………………………………..……….30
Figure 3.5 The Strategic Orientation Moderated Model of Capability and Partnership on Innovativeness…..……………………..………...……55
Figure 4.1 Normal P-P plot of regression standardized residual(The direct effect on product innovativeness)…………………….…..76
Figure 4.2 Normal P-P plot of regression standardized residual(The direct effect on process innovativeness)……………...…….........76
Figure 5.1 Interaction effects between marketing capability and strategic Orientation…………………………………………………………..…102
Figure 5.2 Interaction effects between marketing capability and strategic orientation………………………………………………….……..……103
Figure 5.3 Interaction effects between manufacturing capability and strategic Orientation………………………………………………………….….104
Figure 5.4 Interaction effects between suppliers’ partnership and strategic Orientation……………………………………………………...….…..105
Figure 5.5 Interaction effects between partnership of suppliers and strategic Orientation……………………………………………………………..106
dc.language.isoen
dc.subject夥伴關係zh_TW
dc.subject策略導向zh_TW
dc.subject創新績效zh_TW
dc.subject能力推展zh_TW
dc.subjectpartnershipsen
dc.subjectstrategic orientationen
dc.subjectcapabilitiesen
dc.subjectinnovativenessen
dc.title從策略性能力運用與夥伴關係之觀點
來探討創新程度之提升 - 以生物科技事業為例
zh_TW
dc.titleEnhancing Innovativeness through Strategic Capability Deployment and Partnering Relations – The Cases of Biotechnology Venturesen
dc.typeThesis
dc.date.schoolyear93-1
dc.description.degree博士
dc.contributor.coadvisor陳家聲
dc.contributor.oralexamcommittee方文昌,陳銘薰,廖文昌,莊正民
dc.subject.keyword策略導向,夥伴關係,能力推展,創新績效,zh_TW
dc.subject.keywordpartnerships,innovativeness,capabilities,strategic orientation,en
dc.relation.page157
dc.rights.note未授權
dc.date.accepted2004-11-05
dc.contributor.author-college管理學院zh_TW
dc.contributor.author-dept國際企業學研究所zh_TW
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