請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/19797完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 賴裕和(Yeur-Hur Lai) | |
| dc.contributor.author | Hsin-Yu Hsu | en |
| dc.contributor.author | 徐昕妤 | zh_TW |
| dc.date.accessioned | 2021-06-08T02:19:42Z | - |
| dc.date.copyright | 2015-09-25 | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2015-08-20 | |
| dc.identifier.citation | 中文部分
方圓媛(2010，7月)•口腔及口咽癌患者於治療後身體活動狀況探討•碩士論文，台北：國立台灣大學。 王宏銘、廖俊達、范綱行、吳樹鏗、詹勝傑、閣紫宸(2009)•頭頸部鱗狀細胞癌治療的新進展•腫瘤護理雜誌，9(S)，51-67。 台灣癌症登記中心(2012) •存活分析•取自http://tcr.cph.ntu.edu.tw/uploadimages/Survival_96_100.pdf 吳敏夫、呂宜興、李振川、蕭弘道、張源清、楊政謙…張義芳等(2008)•晚期下咽癌治療分析比較：以單獨同步化學放射治療或是手術合併化學放射治療方式•中華癌醫會誌，24(4)，236-242。 林純美(2009，7月)•頭頸癌病人肩功能於不同量表之比較•碩士論文，台北：國立台灣大學。 林家瑜(2011，5月)•頭頸部癌症病患術後三個月內肩頸功能與身體功能之探討•碩士論文，台北：國立台灣大學。 林廣軒、劉幕台、畢祖平、張東浩、黃昭源、黃勝賢、鍾兆麒(2012)•動態弧形放射線治療與強度調控放射線治療計畫品質比較與劑量驗證於頭頸癌病例之研究•放射線治療與腫瘤學，19(1)，51-61。 胡文郁、羅淑芬(2008)•癌症病人健康相關生活品質之概念與測量工具之評析•安寧療護雜誌，13 (1)，42-57。 許文林(1991)•放射線治療合併化學治療的原則•國防醫學，(13)6，526-531。 陸思慧(2011)，不同強度調控放射線治療技術施於鼻咽癌之劑量比較，碩士論文，台北：陽明大學。 孫秀卿(1999)，男性肝癌病患接受經導管肝動脈栓塞治療期間疲倦型態及其相關因素之探討，碩士論文，台北：台北醫學大學。 黃采薇、王銘志(2007)•頭頸部癌症病患在接受治療期間的症狀問題、事件衝擊及生活品質之探討•弘光學報，51期，11-28。 黃采薇、謝孟臻、賴俊宏、賴秋絨(2006)•乳癌病患接受化學治療期間疲憊及睡眠品質之研究•弘光學報，51期，111-122。 張青蕙(2003)•住院癌症病患疲憊問題及其相關因素之探討，碩士論文，台北：台北醫學大學。 國民健康署(2014，4月) •民國100年癌症登記報告•取自http://www.hpa.gov.tw/BHPNet/Web/Stat/StatisticsShow.aspx?No=201404160001 陳佩靖(2003)•口腔癌病患治療後生活品質及其相關因素探討-橫斷式研究，碩士論文，高雄：高雄醫學大學。 蔡東龍、張學逸(2003)•頭頸癌的外科手術治療•癌症新探，24，8-9。 賴裕和(1998) •門診接受化學治療病人之症狀困擾及居家護理需求探討•護理研究，6(4)，278-279。 賴鵬安、邱仲峰、趙坤山、翁培豐、葉啟源(2006)•不同強度調控放射線治療計畫系統在頭頸癌部腫瘤結果之比較•中華放射技術學雜誌，30(1)，27-40。 羅惠敏、徐南麗、邱慧洳、廖惠娥、劉欣怡(2004)•癌症病患症狀困擾與不確定感關係之探討，慈濟護理雜誌3(1)，72 – 80。 英文部分 Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 85(5), 365-376. Adelstein, D. J., Lavertu, P., Saxton, J. P., Secic, M., Wood, B. G., Wanamaker, J. R., . . . Larto, M. A. (2000). Mature results of a phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with stage III and IV squamous cell carcinoma of the head and neck. Cancer, 88(4), 876-883. Ahles, T. A., & Saykin, A. J. (2007). Candidate mechanisms for chemotherapy-induced cognitive changes. Nat Rev Cancer, 7(3), 192-201. doi: 10.1038/nrc2073. Ahles, T. A., Saykin, A. J., McDonald, B. C., Li, Y., Furstenberg, C. T., Hanscom, B. S., . . . Kaufman, P. A. (2010). Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: impact of age and cognitive reserve. J Clin Oncol, 28(29), 4434-4440. doi: 10.1200/jco.2009.27.0827 Ahles, T. A., Root, J. C., & Ryan, E. L. (2012). Cancer- and cancer treatment-associated cognitive change: an update on the state of the science. J Clin Oncol, 30(30), 3675-3686. doi: 10.1200/jco.2012.43.0116. American Cancer Society(2014a). Chemo brain. Retrieved from http://www.cancer.org/treatment/treatmentsandsideeffects/physicalsideeffects/chemotherapyeffects/chemo-brain American Cancer Society(2014b,February). Treatment options for oral cavity and oropharyngeal cancer by stage. Retrieved from http://www.cancer.org/cancer/oralcavityandoropharyngealcancer/detailedguide/oral-cavity-and-oropharyngeal-cancer-treating-by-stage American Society of Clinical Oncology(ASCO) (2013a, May).Head and Neck cancer. http://www.cancer.net/cancer-types/head-and-neck-cancer American Society of Clinical Oncology(ASCO) (2013b, June). Attention, Thinking, or Memory Problems. Retrieved from http://www.cancer.net/navigating-cancer-care/side-effects/attention-thinking-or-memory-problems Anderson-Hanley, C., Sherman, M. L., Riggs, R., Agocha, V. B., & Compas, B. E. (2003). Neuropsychological effects of treatments for adults with cancer: a meta-analysis and review of the literature. J Int Neuropsychol Soc, 9(7), 967-982. doi: 10.1017/s1355617703970019 Biglia, N., Bounous, V. E., Malabaila, A., Palmisano, D., Torta, D. M., D'Alonzo, M., . . . Torta, R. (2012). Objective and self-reported cognitive dysfunction in breast cancer women treated with chemotherapy: a prospective study. Eur J Cancer Care (Engl), 21(4), 485-492. doi: 10.1111/j.1365-2354.2011.01320.x. Boscolo-Rizzo, P., Stellin, M., Fuson, R., Marchiori, C., Gava, A., & Da Mosto, M. C. (2009a). Long-term quality of life after treatment for locally advanced oropharyngeal carcinoma: surgery and postoperative radiotherapy versus concurrent chemoradiation. Oral Oncol, 45(11), 953-957. doi: 10.1016/j.oraloncology.2009.06.005. Boscolo-Rizzo, P., Gava, A., Baggio, V., Marchiori, C., Stellin, M., Fuson, R., Da Mosto, M. C. (2011b). Matched survival analysis in patients with locoregionally advanced resectable oropharyngeal carcinoma: platinum-based induction and concurrent chemoradiotherapy versus primary surgical resection. Int J Radiat Oncol Biol Phys, 80(1), 154-160. doi: 10.1016/j.ijrobp.2010.01.032. American Joint Committee on Cancer (AJCC).(2010)7 edition of the AJCC Cancer Staging Manual. Chachaj, A., Malyszczak, K., Pyszel, K., Lukas, J., Tarkowski, R., Pudelko, M., . . . Szuba, A. (2010). Physical and psychological impairments of women with upper limb lymphedema following breast cancer treatment. Psychooncology, 19(3), 299-305. doi: 10.1002/pon.1573. Chen, M. L., Miaskowski, C., Liu, L. N., & Chen, S. C. (2012). Changes in perceived attentional function in women following breast cancer surgery. Breast Cancer Res Treat, 131(2), 599-606. doi: 10.1007/s10549-011-1760-3. Chen, S. C., Yu, P. J., Hong, M. Y., Chen, M. H., Chu, P. Y., Chen, Y. J., . . . Lai, Y. H. (2015). Communication dysfunction, body image, and symptom severity in postoperative head and neck cancer patients: factors associated with the amount of speaking after treatment. Support Care Cancer. doi: 10.1007/s00520-014-2587-3. Cheung, M., Chan, A. S., Law, S. C., Chan, J. H., & Tse, V. K. (2000). Cognitive function of patients with nasopharyngeal carcinoma with and without temporal lobe radionecrosis. Arch Neurol, 57(9), 1347-1352. Cheung, Y. B., Thumboo, J., Goh, C., Khoo, K. S., Che, W., & Wee, J. (2004). The equivalence and difference between the English and Chinese versions of two major, cancer-specific, health-related quality-of-life questionnaires. Cancer, 101(12), 2874-2880. doi: 10.1002/cncr.20681. Cheung, Y. T., Shwe, M., Chui, W. K., Chay, W. Y., Ang, S. F., Dent, R. A., . . . Chan, A. (2012). Effects of chemotherapy and psychosocial distress on perceived cognitive disturbances in Asian breast cancer patients. Ann Pharmacother, 46(12), 1645-1655. doi: 10.1345/aph.1R408. Cheung, Yin Ting, Foo, Yu Lee, Shwe, Maung, Tan, Yee Pin, Fan, Gilbert, Yong, Wei Sean, . . . Chan, Alexandre. (2014). Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: Cognitive function (FACT-Cog) in breast cancer patients. Journal of Clinical Epidemiology, 67(7), 811-820. doi: http://dx.doi.org/10.1016/j.jclinepi.2013.12.011. Cimprich, B. (1992a).Attentional fatigue following breast cancer surgery. Res Nurs Health, 15(3), 199-207. Cimprich, B. (1999b). Pretreatment symptom distress in women newly diagnosed with breast cancer. Cancer Nurs, 22(3), 185-194; quiz 195. Cimprich, B., So, H., Ronis, D. L., & Trask, C. (2005c). Pre-treatment factors related to cognitive functioning in women newly diagnosed with breast cancer. Psychooncology, 14(1), 70-78. doi: 10.1002/pon.82. Cimprich, B., Visovatti, M., & Ronis, D. L. (2011d). The Attentional Function Index--a self-report cognitive measure. Psychooncology, 20(2), 194-202. doi: 10.1002/pon.1729. Connie, H. Y., Margaret, H. F., & Michelle, G. (2004). Cognitive Dysfunction, Cancer Symptom Management(3th ed., pp. 635-647). Burlington. MA, Jones & Bartlett Learning. Cull, A., Hay, C., Love, S. B., Mackie, M., Smets, E., & Stewart, M. (1996). What do cancer patients mean when they complain of concentration and memory problems? British Journal Cancer, 74(10), 1674-1679. Deprez, S., Amant, F., Yigit, R., Porke, K., Verhoeven, J., Van den Stock, J., Sunaert, S. (2011). Chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning in breast cancer patients. Human Brain Mapping, 32(3), 480-493. doi: 10.1002/hbm.21033. Earnheart, J. C., Schweizer, C., Crestani, F., Iwasato, T., Itohara, S., Mohler, H., & Luscher, B. (2007). GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states.The Journal of Neuroscience, 27(14), 3845-3854. doi: 10.1523/jneurosci.3609-06.2007. Fayers, N. Aaronson, K. Bjordal, M. Curran, D.& Groenvold, D(1999)EORTC QLQ-C30 scoring manual, 2nd edn:EORTC Quality of Life Group. Emap Publisher, London:UK. Folstein, M., Folstein, S. E., & McHugh, P.(1975).Mini-mental state:a pactical method for grading the cognitive state:a practical method for grading the cognitive state if patient for the clinical.Journal of Psychiatric Research,12(3),189-198. Ganong., W., F. (2008)•Ganong 醫學生理學(二版) (賴義雄、劉婉芳、余佳慧、吳莉玲、陳姿吟、吳世宗譯)•台北市：合記。(原著出版於1963) Gan, H. K., Bernstein, L. J., Brown, J., Ringash, J., Vakilha, M., Wang, L., . . . Siu, L. L. (2011). Cognitive functioning after radiotherapy or chemoradiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys, 81(1), 126-134. doi: 10.1016/j.ijrobp.2010.05.004. Hassan, S. J., & Weymuller, E. A., Jr. (1993). Assessment of quality of life in head and neck cancer patients. Head Neck, 15(6), 485-496. Hermelink, K., Kuchenhoff, H., Untch, M., Bauerfeind, I., Lux, M. P., Buhner, M., Munzel, K. (2010). Two different sides of 'chemobrain': determinants and nondeterminants of self-perceived cognitive dysfunction in a prospective, randomized, multicenter study. Psychooncology, 19(12), 1321-1328. doi: 10.1002/pon.1695. Hickok, J. T., Morrow, G. R., McDonald, S., & Bellg, A. J. (1996). Frequency and correlates of fatigue in lung cancer patients receiving radiation therapy: implications for management. J Pain Symptom Manage, 11(6), 370-377. Hogopian, G.A. (1991). The effects of a weekly radiation therapy newsletter on patients. Oncology Nursing Forum, 18(7), 1199-1203. Jacobs, S. R., Jacobsen, P. B., Booth-Jones, M., Wagner, L. I., & Anasetti, C. (2007). Evaluation of the functional assessment of cancer therapy cognitive scale with hematopoietic stem cell transplant patients. J Pain Symptom Manage, 33(1), 13-23. doi: 10.1016/j.jpainsymman.2006.06.011. Kellogg, R. T.,(2012). Fundamentals of cognitive psychology(2th ed). Saint Louis University, USA：SAGE Publications. Kyriaki, M., Eleni, T., Efi, P., Ourania, K., Vassilios, S., & Lambros, V. (2001). The EORTC core quality of life questionnaire (QLQ-C30, version 3.0) in terminally ill cancer patients under palliative care: validity and reliability in a Hellenic sample. Int J Cancer, 94(1), 135-139. Lue, B. H., Huang, T. S., & Chen, H. J. (2008). Physical distress, emotional status, and quality of life in patients with nasopharyngeal cancer complicated by post-radiotherapy endocrinopathy. International Journal of Radiation Oncology • Biology • Physics (IJROBP), 70(1), 28-34. doi: 10.1016/j.ijrobp.2007.06.053. Macmillan Cancer Support(2013,June). Mild cognitive impairment (MCI). Retrieved from http://www.macmillan.org.uk/Cancerinformation/Livingwithandaftercancer/Symptomssideeffects/Othersymptomssideeffects/MildcognitiveimpairmentMCI.aspx Maruff, P., Falleti, M. G., & Collie, A. (2004). The cognitive sequelae of standard-dose adjuvant chemotherapy in women with breast carcinoma. Results of a prospective, randomized, longitudinal trial. Cancer, 101(9), 2143-2144; author reply 2144-2145. doi: 10.1002/cncr.20601. Matsuda, T., Takayama, T., Tashiro, M., Nakamura, Y., Ohashi, Y., & Shimozuma, K. (2005). Mild cognitive impairment after adjuvant chemotherapy in breast cancer patients--evaluation of appropriate research design and methodology to measure symptoms. Breast Cancer, 12(4), 279-287. McCorkle, R., & Young, K. (1978). Development of a symptom distress scale. Cancer Nursing, 1(5), 373-378. Meeter, M., Talamini, L., Schmitt, J. A., & Riedel, W. J. (2006). Effects of 5-HT on memory and the hippocampus: model and data. Neuropsychopharmacology, 31(4), 712-720. doi: 10.1038/sj.npp.1300869. Mehnert, A., Scherwath, A., Schirmer, L., Schleimer, B., Petersen, C., Schulz-Kindermann, F., . . . Koch, U. (2007). The association between neuropsychological impairment, self-perceived cognitive deficits, fatigue and health related quality of life in breast cancer survivors following standard adjuvant versus high-dose chemotherapy. Patient Education and Counseling, 66(1), 108-118. doi: 10.1016/j.pec.2006.11.005. Moon, Seongmi, Kim, Sun-Hee, & Kim, Mi-Ja. (2011). Perceived Cognitive Function and Related Factors in Korean Women With Breast Cancer. Asian Nursing Research, 5(2), 141-150. doi: http://dx.doi.org/10.1016/S1976-1317(11)60022-4. Nail, L. M., & Winningham, M. L. (1995). Fatigue and weakness in cancer patients: the symptoms experience. Semin Oncol Nurs, 11(4), 272-278. National Cancer Institute(NCI) (2014, Fedbruary). SEER Stat Fact Sheets: Oral Cavity and Pharynx Cancer. Retrieved from http://seer.cancer.gov/statfacts/html/oralcav.html National Comprehensive Cancer Network(NCCN).(2013) NCCN Clinical Practice Guidelines in Oncology: Head and Neck. Retrieved from http://oralcancerfoundation.org/treatment/pdf/head-and-neck.pdf National Cancer Institude(NCI).( 2013, June 14). Cancer Statistics. Retrieved from http://seer.cancer.gov/statfacts/html/oralcav.html. North American Nursing Diagnosis Association(2012). NANDA International nursing diagnoses : definitions & classification 2012-2014. Chichester, UK. : Wiley-Blackwell. Oxman, T. E., & Silberfarb, P. M. (1980). Serial cognitive testing in cancer patients receiving chemotherapy. Am J Psychiatry, 137(10), 1263-1265. Petersen, R. C., Doody, R., Kurz, A., Mohs, R. C., Morris, J. C., Rabins, P. V., . . . Winblad, B. (2001). Current concepts in mild cognitive impairment. Arch Neurol, 58(12), 1985-1992. Reid-Arndt, S. A., Hsieh, C., & Perry, M. C. (2010). Neuropsychological functioning and quality of life during the first year after completing chemotherapy for breast cancer. Psychooncology, 19(5), 535-544. doi: 10.1002/pon.1581. Rogers, L. Q., Courneya, K. S., Robbins, K. T., Rao, K., Malone, J., Seiz, A., . . . Burra, V. (2008). Factors associated with fatigue, sleep, and cognitive function among patients with head and neck cancer. Head Neck, 30(10), 1310-1317. doi: 10.1002/hed.20873. Seruga, Bostjan, Zhang, Haibo, Bernstein, Lori J., & Tannock, Ian F. (2008). Cytokines and their relationship to the symptoms and outcome of cancer. Nature Reviews Cancer, 8(11), 887-899. Servaes, P., Verhagen, C. A., & Bleijenberg, G. (2002). Relations between fatigue, neuropsychological functioning, and physical activity after treatment for breast carcinoma: daily self-report and objective behavior. Cancer, 95(9), 2017-2026. doi: 10.1002/cncr.10891. Silverman, D. H., Dy, C. J., Castellon, S. A., Lai, J., Pio, B. S., Abraham, L., Ganz, P. A. (2007). Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5-10 years after chemotherapy. Breast Cancer Research and Treatment, 103(3), 303-311. doi: 10.1007/s10549-006-9380-z. Sternberg, J. R., Sternberg, K., Mio, J.,(2012) Cognitive psychology(5th ed). Belmont, CA : Wadsworth/Cengage Learning. Ustun, T. B., Chatterji, S., Kostanjsek, N., Rehm, J., Kennedy, C., Epping-Jordan, J., Saxena, S., Korff, M. V., & Pull, C. (2010). Developing the World Health Organization Disability Assessment Schedule 2.0. Bulletin of World Health Organization, 88(11), 815–823. Verstappen, C. C., Heimans, J. J., Hoekman, K., & Postma, T. J. (2003). Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management. Drugs, 63(15), 1549-1563. Wanger L.I., Lai J S., Cella D., Sweet J. & Forrestal S.(2004)Chemotherapy-related cognitive deficits:development of the FACT-Cog instrument. Annals of Behavioral Medicine 27(S10). Wekipedia(2014，April). Cognitive function. Retrived from http://en.wikipedia.org/wiki/Cognition#cite_note-1 World Health Organization Disability Assessment Schedule II (WHODASII) (2001). Retrieved from http://www.who.int/icidh/whodas/index.html. Yoshii, Y. (2008). Pathological review of late cerebral radionecrosis. Brain Tumor Pathol, 25(2), 51-58. doi: 10.1007/s10014-008-0233-9. Yuen, H. K., Sharma, A. K., Logan, W. C., Gillespie, M. B., Day, T. A., & Brooks, J. O. (2008). Radiation dose, driving performance, and cognitive function in patients with head and neck cancer. Radiotherapy and Oncology 87(2), 304-307. doi: 10.1016/j.radonc.2008.03.020. Yucel, B., Akkas, E. A., Okur, Y., Eren, A. A., Eren, M. F., Karapinar, H., . . . Kilickap, S. (2014). The impact of radiotherapy on quality of life for cancer patients: a longitudinal study. Supportive Care in Cancer. doi: 10.1007/s00520-014-2235-y. Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361-370. Zhao, H. P., Liu, Y., Li, H. L., Ma, L., Zhang, Y. J., & Wang, J. (2013). Activity limitation and participation restrictions of breast cancer patients receiving chemotherapy: psychometric properties and validation of the Chinese version of the WHODAS 2.0. Quality of Life Research, 22(4), 897-906. doi: 10.1007/s11136-012-0212-9. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/19797 | - |
| dc.description.abstract | 頭頸癌治療，口腔癌早期以手術治療為首要，侵襲性口腔癌及鼻咽癌以放射線治療或化學同步放射治療為主，治療可能會造成中樞神經系統毒性，引起治療後認知功能缺損。臨床需要簡易、可信賴的評估工具，評估認知功能並可改善認知缺損對其生活品質的衝擊。本研究目的為測試中文版「世界衛生組織障礙評估手冊2.0-認知」（WHODAS 2.0-Cognition）之信度及效度。
本研究採量表測試研究設計，使用結構式問卷進行資料收集，研究工具包括：基本屬性問卷、癌症及治療相關特質、世界衛生組織障礙評估手冊-認知及、歐洲癌症治療與研究組織之癌症患者生命品質測定量表、醫院焦慮憂鬱量表及症狀嚴重度量表。 研究結果顯示：(1)本量表具有良好的內在一致性信度；(2)具有建構效度，萃取一個因素結構，解釋變異量為61.04%；(3)與生活品質、焦慮、疲倦及症狀嚴重度具有同時效度；(4)對接受不同治療方式病人的認知功能具有區辦效度。本研究結果顯示中文版「世界衛生組織障礙評估手冊2.0-認知」具有良好的信度及效度。本量表適用於台灣臨床頭頸癌病人認知功能評估。 | zh_TW |
| dc.description.abstract | Chemoradiotherapy (CCRT) is one of the major treatment modalities for advanced oral cavity cancer and for most nasopharyngeal carcinoma. However, both chemotherapy (CT) and radiation therapy (RT) might also cause the central nervous system toxicity and result in cognition impairment. Thus, an easily and reliable scale for clinical assessment is needed for assessing patients’ cognition function related these treatments. The purpose of the study was to examine the psychometric properties of the World Health Organization Disability Assessment Schedule 2.0-Cognition (WHODAS 2.0-Cognition).
This is an instrument testing study. We used the World Health Organization Disability Assessment Schedule 2.0 –Cognition (WHODAS 2.0-Cognition), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLO-C30), Hospital Anxiety and Depression Scale (HADS), Symptom Severity Scale (SSS), and background information form to measure the psychometrics of WHODAS-cognition Chinese version. The results showed that: (1) the Chinese-version WHODAS 2.0-Cognition had good internal consistency reliability; (2) clear one factor structure with 61.04% of the variance examined by exploratory factor analysis; (3) had theoretically supported convergent validity between WHODAS 2.0-Cognition scale and quality of life, anxiety, fatigue, and symptom severity; (4) had theoretically supported discriminant validity which can identify the differences of the levels of cognition among various treatment modalities. The WHODAS 2.0-Cognition is a psychometrically satisfactory instrument. The scale is appropriate in measuring the cognition function of head and neck cancer patients in Taiwan. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-08T02:19:42Z (GMT). No. of bitstreams: 1 ntu-104-R01426015-1.pdf: 1281445 bytes, checksum: 438a6bb50978b8282d01f984be0e2b97 (MD5) Previous issue date: 2015 | en |
| dc.description.tableofcontents | 中文摘要…………………………………………………………………………..…...i
英文摘要……………………………………………………………………….……...ii 第一章 緒論…………………………………………………………………...…...…1 第一節 研究動機及重要性……………………………………………………..1 第二節 研究目的………………………………………………………………..3 第二章 文獻查證……………………………………………………………………..4 第一節 頭頸癌疾病與治療簡介………………………………………………..4 第二節 認知功能………………………………………………………………11 第三節 治療相關認知功能影響因素…………………………………………12 第四節 癌症相關認知功能影響因素…………………………………………15 第五節 常見認知量表與世界衛生組織障礙評估-認知量表………………...18 第六節 研究假設………………………………………………………………20 第三章 研究方法……………………………………………………………………21 第一節 研究設計及步驟………………………………………………………21 第二節 研究工具………………………………………………………………22 第三節 資料處理與分析………………………………………………………25 第四節 研究倫理考量…………………………………………………………27 第四章 研究結果……………………………………………………………………28 第一節 人口學特性及疾病治療特質…………………………………………28 第二節 認知功能量表分析……………………………………………………29 第五章 討論…………………………………………………………………………33 第一節 量表信度………………………………………………………………33 第二節 量表效度………………………………………………………………35 第六章 結論與建議…………………………………………………………………40 第一節 研究限制與建議………………………………………………………40 第二節 結論……………………………………………………………………41 第七章 參考文獻……………………………………………………………………42 表目錄 表1 資料分析一覽表…………………………………………………….……25 表2 人口學特性及疾病治療特質………………………………………….…53 表3 WHODAS 2.0-Cognition平均值與Cronbach's α值…………………..…55 表4 WHODAS 2.0-Cognition因素分析……………………………….………56 表5比較病人不同之人口學、疾病與治療特質跟認知差異……………….…57 表6 WHODAS 2.0-Cognition量表與相關變項之Pearson's correlation…..…58 | |
| dc.language.iso | zh-TW | |
| dc.title | 世界衛生組織障礙評估手冊-認知量表之中文版測試於頭頸癌症病患 | zh_TW |
| dc.title | Validation of the WHODAS 2.0-Cognition Chinese Version in Head and Neck Cancer Patients | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 103-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 王成平(Chen-Ping Wang),陳淑卿(Shu-Cing Chen) | |
| dc.subject.keyword | 頭頸癌,放射線治療,化學合併放射線同步治療,認知功能,量表測試, | zh_TW |
| dc.subject.keyword | head and neck cancer,RT,CCRT,cognitive function,psychometric testing, | en |
| dc.relation.page | 58 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2015-08-20 | |
| dc.contributor.author-college | 醫學院 | zh_TW |
| dc.contributor.author-dept | 護理學研究所 | zh_TW |
| 顯示於系所單位： | 護理學系所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-104-1.pdf 目前未授權公開取用 | 1.25 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。