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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/99263完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 林啟萬 | zh_TW |
| dc.contributor.advisor | Chii-Wann Lin | en |
| dc.contributor.author | 林翩翩 | zh_TW |
| dc.contributor.author | Pien-Pien Lin | en |
| dc.date.accessioned | 2025-08-21T17:02:11Z | - |
| dc.date.available | 2025-08-22 | - |
| dc.date.copyright | 2025-08-21 | - |
| dc.date.issued | 2025 | - |
| dc.date.submitted | 2025-08-04 | - |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/99263 | - |
| dc.description.abstract | 腸音能夠反映腸道蠕動狀態,具有作為非侵入式生理指標的潛力。然而,傳統聽診法主觀性高且缺乏標準化,限制其臨床應用價值。本研究旨在探討以腸音作為生理指標的可行性,並建立一套客觀、自動化且具臨床實用性的術後腸音分析架構。共納入 14 位接受全身麻醉之非腸胃道手術病人,於圍手術期五個時間點,從四個標準化腹部位置記錄腸音,使用自行組裝之聽診器式麥克風進行收音。於時域方面,提取總腸音時長、事件發生次數與平均持續時間等特徵,並比較人工與自動分段演算法之結果;於頻域方面,則建立「峰值頻率直方圖(Peak Frequency Histogram, PFH)」方法,以視覺化不同時間點之主頻分佈情形。在所有分析指標中,針對 288–384 Hz 頻段所建立之 PFH 指標展現出最一致且具統計顯著性的術後回復趨勢,顯示其作為腸道功能臨床指標之潛力。本研究所提出之分析流程具備可行性、重現性與生理意義,為建立標準化腸音評估作業流程奠定基礎。未來若進一步整合系統,將有望實現即時智慧腸音監測,應用於術後照護、自律神經功能評估及腸胃道疾病處置等臨床場域。 | zh_TW |
| dc.description.abstract | Bowel sounds (BSs) reflect intestinal motility and hold promise as non-invasive physiological indicators. However, traditional auscultation methods are subjective and lack standardization, limiting their clinical utility. This study aimed to explore the feasibility of using BSs as physiological indicators and to develop an objective, automated, and clinically applicable framework for postoperative BS analysis. A total of 14 patients undergoing non-gastrointestinal surgery under general anesthesia were enrolled. BSs were recorded at five perioperative time points from four standardized abdominal sites using a self-built stethoscope microphone. Time-domain features—such as total sound duration, occurrence count, and average duration—were extracted using both manual and automated segmentation algorithms. In parallel, a frequency-domain method was established based on the Peak Frequency Histogram (PFH), which visualized the dominant frequency distribution across time. Among all indicators, a PFH-based index targeting the 288–384 Hz band showed the most consistent and statistically significant recovery trend postoperatively, suggesting its potential as a robust clinical marker of intestinal function. The analysis protocol demonstrated feasibility, reproducibility, and physiological interpretability, paving the way for a standardized operating procedure. Future system integration may enable real-time, intelligent bowel monitoring in postoperative care, autonomic function assessment, and gastrointestinal disorder management. | en |
| dc.description.provenance | Submitted by admin ntu (admin@lib.ntu.edu.tw) on 2025-08-21T17:02:11Z No. of bitstreams: 0 | en |
| dc.description.provenance | Made available in DSpace on 2025-08-21T17:02:11Z (GMT). No. of bitstreams: 0 | en |
| dc.description.tableofcontents | Verification Letter from the Oral Examination Committee i
Acknowledgements ii 摘要 iv Abstract v Contents vii List of Figures x List of Tables xii Denotation xiii Chapter 1 Introduction 1 1.1 Background of Bowel Sounds 2 1.2 Mathematical Modeling of Bowel Sounds 4 1.3 Current Research Methods and Findings 8 1.4 Clinical Scenarios and Needs 12 1.4.1 Anesthesia and Surgery 12 1.4.2 Postoperative Complications 13 1.4.3 Postoperative Dietary Progression 14 1.4.4 Clinical Challenges and Unmet Needs 16 1.4.5 The Potential of Bowel Sounds 17 1.5 Research Objectives 18 Chapter 2 Methodology 20 2.1 Overall Research Framework 22 2.2 Recruitment Process 24 2.2.1 Participant Data 24 2.2.2 Auscultation Sites 25 2.2.3 Bowel Sound Acquisition Procedure 28 2.2.4 Timing of Bowel Sound Acquisition 29 2.3 Hardware Setup for Bowel Sound Acquisition 31 2.4 Manual Annotation 33 2.5 Signal Preprocessing 34 2.6 Time-Domain Analysis 36 2.7 Frequency-Domain Analysis 38 2.8 Indicator Development 41 2.9 Statistical Methods 44 Chapter 3 Results and Discussion 45 3.1 Manual Annotation Analysis 45 3.2 Automated Time-Domain Analysis 48 3.2.1 Accuracy of Automated Bowel Sound Annotation 48 3.2.2 Performance Comparison Across Recording Locations 51 3.2.3 Temporal Feature Analysis 52 3.3 Automated Frequency-Domain Analysis 56 3.3.1 PFH Construction 56 3.3.2 PFH Trend Analysis 59 3.3.3 Sliding Sum Index and Statistical Validation 61 3.3.4 Establishment of the PFH-Based Frequency-Domain Indicator 64 3.4 Physiological Interpretation of Indicators 66 3.4.1 Baseline Selection and Implications 66 3.4.2 Bowel Sounds and the Autonomic Nervous System 68 3.4.3 Mechanical Interpretation of Frequency Shifts 70 3.4.4 Interindividual Variability of Bowel Sounds 71 Chapter 4 Prospects and Conclusion 74 4.1 Standard Procedure Establishment 74 4.2 Clinical Applications and Disease Relevance 76 4.3 Technological Development and System Integration 79 4.4 Conclusion 80 References 82 Appendix A — Institutional Review Board Approval Certificate 88 Appendix B — Diagnoses and Surgical Information of Enrolled Patients 89 Appendix C — Electret Condenser Microphone Specifications 91 | - |
| dc.language.iso | en | - |
| dc.subject | 峰值頻率直方圖 | zh_TW |
| dc.subject | 頻域分析 | zh_TW |
| dc.subject | 聲學訊號分析 | zh_TW |
| dc.subject | 術後監測 | zh_TW |
| dc.subject | 訊號處理 | zh_TW |
| dc.subject | 腸音 | zh_TW |
| dc.subject | 時域分析 | zh_TW |
| dc.subject | Postoperative Monitoring | en |
| dc.subject | Acoustic Signal Analysis | en |
| dc.subject | Frequency Domain Analysis | en |
| dc.subject | Time Domain Analysis | en |
| dc.subject | Signal Processing | en |
| dc.subject | Peak Frequency Histogram | en |
| dc.subject | Bowel Sound | en |
| dc.title | 峰值頻率直方圖指標於非腸胃道手術病患術後腸音評估之可行性探討 | zh_TW |
| dc.title | A Feasibility Study on Peak Frequency Histogram Index for Postoperative Bowel Sound Assessment in Non-Gastrointestinal Surgery Patients | en |
| dc.type | Thesis | - |
| dc.date.schoolyear | 113-2 | - |
| dc.description.degree | 碩士 | - |
| dc.contributor.oralexamcommittee | 趙福杉;戴浩志;劉治民;劉建昇 | zh_TW |
| dc.contributor.oralexamcommittee | Fu-Shan Jaw;Hao-Chih Tai;Chih-Min Liu;Chien-Sheng Liu | en |
| dc.subject.keyword | 腸音,峰值頻率直方圖,訊號處理,時域分析,頻域分析,聲學訊號分析,術後監測, | zh_TW |
| dc.subject.keyword | Bowel Sound,Peak Frequency Histogram,Signal Processing,Time Domain Analysis,Frequency Domain Analysis,Acoustic Signal Analysis,Postoperative Monitoring, | en |
| dc.relation.page | 91 | - |
| dc.identifier.doi | 10.6342/NTU202502467 | - |
| dc.rights.note | 未授權 | - |
| dc.date.accepted | 2025-08-06 | - |
| dc.contributor.author-college | 工學院 | - |
| dc.contributor.author-dept | 醫學工程學系 | - |
| dc.date.embargo-lift | N/A | - |
| 顯示於系所單位: | 醫學工程學研究所 | |
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