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  1. NTU Theses and Dissertations Repository
  2. 工學院
  3. 醫學工程學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/92234
完整後設資料紀錄
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dc.contributor.advisor呂東武zh_TW
dc.contributor.advisorTung-Wu Luen
dc.contributor.author蘇楷文zh_TW
dc.contributor.authorKai-Wen Kevin Suen
dc.date.accessioned2024-03-17T16:16:47Z-
dc.date.available2024-03-18-
dc.date.copyright2024-03-16-
dc.date.issued2024-
dc.date.submitted2024-02-19-
dc.identifier.citation[1] Hsing-Po Huang, Chien-Chung Kuo, Shiuan-Huei Lu, Sheng-Chang Chen,Tsung-Jung Ho, and Tung-Wu Lu. Synergistic multi-joint kinematic strategies to reduce tripping risks during obstacle-crossing in older long-term tai-chichuan practitioners. Frontiers in Aging Neuroscience, 14:961515, 2022.
[2] Hao-Ling Chen and Tung-Wu Lu. Comparisons of the joint moments betweenleading and trailing limb in young adults when stepping over obstacles. Institute of Biomedical Engineering, National Taiwan University, Taiwan, ROC,December 2004. Accepted.
[3] Scott L Delp, Frank C Anderson, Allison S Arnold, Patrick Loan, Ayman Habib,Charles T John, and Ely Guendelman. Opensim: Open-source software tocreate and analyze dynamic simulations of movement. IEEE Transactions onBiomedical Engineering, 54(11):1940–1950, 2007.
[4] Alan KM Lai, Allison S Arnold, and James M Wakeling. Modelling the effectof subject-specific geometries and mechanical properties on the swing phase ofwalking. Journal of Biomechanics, 62:207–212, 2017.
[5] Marko Ackermann and Antonie J van den Bogert. Optimality principles formodel-based prediction of human gait. Journal of biomechanics, 43(6):1055–1060, 2010.
[6] Shih-Yen Chen, Biomechanics Yu, and Shunfang Zhang. Validation of subjectspecific musculoskeletal models using an optimization-based sensitivity analysisapproach. Journal of biomechanical engineering, 140(9):091003, 2018.
[7] Fred C Anderson and Marcus G Pandy. Dynamic optimization of human walking. Journal of biomechanical engineering, 123(5):381–390, 2001.
[8] Jiheui Han and Hyunseok Samuel Jeon. Differences in joint kinematics andmuscle activities between obstacle and non-obstacle side during step-over movements. Gait & Posture, 46:99–105, 2016.
[9] Anna N Lay, Chris J Hass, and Robert J Gregor. The effects of sloped surfaces on locomotion: an electromyographic analysis. Journal of Biomechanics,39(9):1621–1628, 2006.
[10] Mohammad M Ardestani, Mehran Moazen, Zhongmin Jin, and Zhuo P Luo.Subject-specific ankle joint finite element analysis. Journal of Biomechanics,46(11):1992–1998, 2013.
[11] Ming-Chun Chiu and Hsiu-Wen Wu. Development of a foot-ankle model forhigh-heeled shoes. Gait & Posture, 41(2):544–549, 2015.
[12] Ines Kutzner, Jan Richter, Kristina Gordt, J¨orn Dymke, Philipp Damm, andGeorg N Duda. Does altered muscle activity cause higher tibiofemoral compressive forces in patients with knee osteoarthritis? Journal of OrthopaedicResearch, 31(7):979–986, 2013.
[13] Richard Baker and James E Robb. Predicting the influence of muscle-tendonarchitecture on the hysteresis in the human ankle joint during passive cyclicdorsiflexion. Journal of Biomechanics, 34(9):1203–1212, 2001.
[14] Katherine S Rudolph, Michael J Axe, and Thomas S Buchanan. Co-activationrevisited: influence of task specificity and predictability on co-activation of theknee musculature. Journal of Electromyography and Kinesiology, 23(1):53–58,2013.
[15] Rezaul K Begg, Marimuthu Palaniswami, and Brendan Owen. Support vectormachines for automated gait classification. IEEE Transactions on BiomedicalEngineering, 52(5):828–838, 2005.
[16] Boyeong Hong, Pilwon Kim, Dongjin Lee, Minyoung Sim, and Hyunjin Yoon.Automated gait analysis using dynamic time warping and support vector machines. Sensors, 19(24):5433, 2019.
[17] N Stergiou, JL Jensen, BT Bates, SD Scholten, and G Tzetzis. A dynamical systems investigation of lower extremity coordination during running overobstacles. Clinical Biomechanics, 16:213–221, 2001.
[18] N Stergiou, SD Scholten, JL Jensen, and D Blanke. Intralimb coordinationfollowing obstacle clearance during running: the effect of obstacle height. Gait& Posture, 13:210–220, 2001.
[19] R Burgess-Limerick, B Abernethy, and RJ Neal. Relative phase quantifiesinterjoint coordination. Journal of Biomechanics, 26:91–94, 1993.
[20] Xingchen Wang, Maria Kyrarini, Danijela Risti´c-Durrant, Matthias Spranger,and Axel Gr¨aser. Monitoring of gait performance using dynamic time warping on imu-sensor data. In 2016 IEEE International Symposium on MedicalMeasurements and Applications (MeMeA), pages 1–6, 2016.
[21] Subhrangshu Adhikary and Arindam Ghosh. Dynamic time warping approachfor optimized locomotor impairment detection using biomedical signal processing. Biomedical Signal Processing and Control, 72:103321, 2022.
[22] Nathaniel E. Helwig, Sungjin Hong, Elizabeth T. Hsiao-Wecksler, and John D.Polk. Methods to temporally align gait cycle data. Journal of Biomechanics,44(3):561–566, 2011
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dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/92234-
dc.description.abstractWalking and obstacle negotiation are fundamental locomotor tasks performeddaily. In performing these activities, the human musculoskeletal system must maintain stability and generate sufficient forces to propel the body forward while overcoming environmental challenges.
In contrast to normal walking however, the transition to negotiating environmental challenges requires adaptive adjustments in gait patterns and muscle activitiesto safely and efficiently clear obstacles - the mechanism of which remains largelyelusive. While existing studies that have examined obstacle negotiation have primarily focused on the kinematic aspects of gait, such as step length, step width,and clearance over the obstacle have contributed to our understanding of obstaclenegotiation strategies and trends, a comprehensive analysis of the underlying muscleforces similar to those in studies of normal and pathological gait and running onlevel ground has not yet been conducted.
In recent years, advancements in technology and access to powerful computationhave driven a shift in the field towards simulation in biomechanics. OpenSim offerslibraries that allow researchers to create detailed musculoskeletal models of the human body, encompassing bones, joints, and muscles, while also providing advancedcapabilities for performing Inverse Kinematics (IK). IK enables the estimation ofjoint angles and positions from motion capture data, a crucial component in thesimulation of obstacle negotiation. Furthermore, OpenSim facilitates the simulationof muscle forces, activation, and joint dynamics, providing invaluable insights intohow muscles contribute to human movement.
For studies involving patient data, OpenSim’s ability to create patient-specificmusculoskeletal models and its integration with motion capture systems offer advantages in incorporating real-world movement data into simulations, potentiallyyielding more accurate practical insights in the interpretation through analysis ofsimulated data. To date, there is no study that has conducted analysis of patientspecific muscle simulations during obstacle negotiation.
The objective of this thesis is to explore the effects of obstacle height on jointmoments, muscle forces, and activations involved in these activities. using simulations based on data collected from young, healthy subjects. Due to the simulatednature of the data, kinematics was compared with established significant effects andtrends found in the calculated results in existing literature.
If the simulated muscle activation patterns during obstacle negotiation can bereasonably representative of documented significant effects and trends, it could augment the kinematic analyses currently performed in the literature, and potentiallyenhance research directions in biomechanics, rehabilitation, and robotics
zh_TW
dc.description.abstractWalking and obstacle negotiation are fundamental locomotor tasks performeddaily. In performing these activities, the human musculoskeletal system must maintain stability and generate sufficient forces to propel the body forward while overcoming environmental challenges.
In contrast to normal walking however, the transition to negotiating environmental challenges requires adaptive adjustments in gait patterns and muscle activitiesto safely and efficiently clear obstacles - the mechanism of which remains largelyelusive. While existing studies that have examined obstacle negotiation have primarily focused on the kinematic aspects of gait, such as step length, step width,and clearance over the obstacle have contributed to our understanding of obstaclenegotiation strategies and trends, a comprehensive analysis of the underlying muscleforces similar to those in studies of normal and pathological gait and running onlevel ground has not yet been conducted.
In recent years, advancements in technology and access to powerful computationhave driven a shift in the field towards simulation in biomechanics. OpenSim offerslibraries that allow researchers to create detailed musculoskeletal models of the human body, encompassing bones, joints, and muscles, while also providing advancedcapabilities for performing Inverse Kinematics (IK). IK enables the estimation ofjoint angles and positions from motion capture data, a crucial component in thesimulation of obstacle negotiation. Furthermore, OpenSim facilitates the simulationof muscle forces, activation, and joint dynamics, providing invaluable insights intohow muscles contribute to human movement.
For studies involving patient data, OpenSim’s ability to create patient-specificmusculoskeletal models and its integration with motion capture systems offer advantages in incorporating real-world movement data into simulations, potentiallyyielding more accurate practical insights in the interpretation through analysis ofsimulated data. To date, there is no study that has conducted analysis of patientspecific muscle simulations during obstacle negotiation.
The objective of this thesis is to explore the effects of obstacle height on jointmoments, muscle forces, and activations involved in these activities. using simulations based on data collected from young, healthy subjects. Due to the simulatednature of the data, kinematics was compared with established significant effects andtrends found in the calculated results in existing literature.
If the simulated muscle activation patterns during obstacle negotiation can bereasonably representative of documented significant effects and trends, it could augment the kinematic analyses currently performed in the literature, and potentiallyenhance research directions in biomechanics, rehabilitation, and robotics
en
dc.description.provenanceSubmitted by admin ntu (admin@lib.ntu.edu.tw) on 2024-03-17T16:16:47Z
No. of bitstreams: 0
en
dc.description.provenanceMade available in DSpace on 2024-03-17T16:16:47Z (GMT). No. of bitstreams: 0en
dc.description.tableofcontentsContents
Page
Acknowledgements i
Abstract iii
Contents vii
List of Figures ix
List of Tables xi
Chapter 1 Introduction 1
1.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1.2 Research Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Chapter 2 Methods 5
2.1 Research Design . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
2.2 Participants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
2.3 Data Collection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
2.4 Simulation Using OpenSim . . . . . . . . . . . . . . . . . . . . . . 6
2.4.1 The Musculoskeletal Model . . . . . . . . . . . . . . . . . . . . . . 7
2.4.2 Subject-Specific Scaling . . . . . . . . . . . . . . . . . . . . . . . 8
2.4.3 Simulating Joint Angles and Joint Moments . . . . . . . . . . . . . 8
2.4.4 Simulating Muscle Forces and Activations . . . . . . . . . . . . . . 8
2.5 Data Preprocessing . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.5.1 Data Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.5.2 Outlier Detection and Removal . . . . . . . . . . . . . . . . . . . . 9
2.5.3 Kinematic Data Processing . . . . . . . . . . . . . . . . . . . . . . 10
2.5.4 Normalization of Forces and Moments . . . . . . . . . . . . . . . . 10
2.5.5 Data Aggregation . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.5.6 Key Gait Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.5.6.1 Crossing with the Leading Leg . . . . . . . . . . . . . 11
2.6 Data Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.6.1 Analysis of Variance (ANOVA) . . . . . . . . . . . . . . . . . . . . 12
2.6.2 Post hoc Tests . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
2.6.3 Dask for Parallel Processing . . . . . . . . . . . . . . . . . . . . . 13
2.6.4 Interpretation of Results . . . . . . . . . . . . . . . . . . . . . . . . 13
Chapter 3 Results 15
3.1 Joint Angles from Inverse Kinematics . . . . . . . . . . . . . . . . . 15
3.2 Joint Moments from Inverse Dynamics . . . . . . . . . . . . . . . . 18
Chapter 4 Discussion 21
Chapter 5 Conclusion 23
5.1 Future Directions . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
References 27
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dc.language.isoen-
dc.subject步態分析zh_TW
dc.subjectObstacle Negotiationzh_TW
dc.subject模擬zh_TW
dc.subjectGait Analysisen
dc.subjectObstacle Negotiationen
dc.subjectSimulationen
dc.title障礙高度於模擬下肢肌肉力量和活動的影響zh_TW
dc.titleEffects of Obstacle Heights on Simulated Lower Extremity Muscle Forcesen
dc.typeThesis-
dc.date.schoolyear112-1-
dc.description.degree碩士-
dc.contributor.oralexamcommittee彭志維;林正忠zh_TW
dc.contributor.oralexamcommitteeChih-Wei Peng;Cheng-Chung Linen
dc.subject.keyword步態分析,模擬,Obstacle Negotiation,zh_TW
dc.subject.keywordGait Analysis,Simulation,Obstacle Negotiation,en
dc.relation.page30-
dc.identifier.doi10.6342/NTU202400609-
dc.rights.note未授權-
dc.date.accepted2024-02-19-
dc.contributor.author-college工學院-
dc.contributor.author-dept醫學工程學系-
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