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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 蘇玫尹 | zh_TW |
| dc.contributor.advisor | Mei-Yin Su | en |
| dc.contributor.author | 林冠妤 | zh_TW |
| dc.contributor.author | Kuan-Yu Lin | en |
| dc.date.accessioned | 2024-03-07T16:14:54Z | - |
| dc.date.available | 2024-03-08 | - |
| dc.date.copyright | 2024-03-07 | - |
| dc.date.issued | 2024 | - |
| dc.date.submitted | 2024-02-04 | - |
| dc.identifier.citation | Addison, P. D., Neligan, P. C., Ashrafpour, H., Khan, A., Zhong, A., Moses, M., . . . Pang, C. Y. (2003). Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction. Am J Physiol Heart Circ Physiol, 285(4), H1435-1443. doi:10.1152/ajpheart.00106.2003
Araújo, C. G., Duarte, C. V., Gonçalves Fde, A., Medeiros, H. B., Lemos, F. A., & Gouvêa, A. L. (2011). Hemodynamic responses to an isometric handgrip training protocol. Arq Bras Cardiol, 97(5), 413-419. doi:10.1590/s0066-782x2011005000102 Badrov, M. B., Bartol, C. L., DiBartolomeo, M. A., Millar, P. J., McNevin, N. H., & McGowan, C. L. (2013). Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women. Eur J Appl Physiol, 113(8), 2091-2100. doi:10.1007/s00421-013-2644-5 Bailey, T. G., Birk, G. K., Cable, N. T., Atkinson, G., Green, D. J., Jones, H., & Thijssen, D. H. (2012). Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise. Am J Physiol Heart Circ Physiol, 303(5), H533-538. doi:10.1152/ajpheart.00272.2012 Banks, L., Wells, G. D., Clarizia, N. A., Jean-St-Michel, E., McKillop, A. L., Redington, A. N., & McCrindle, B. W. (2016). Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults. Appl Physiol Nutr Metab, 41(8), 903-906. doi:10.1139/apnm-2016-0024 Barbosa, T. C., Machado, A. C., Braz, I. D., Fernandes, I. A., Vianna, L. C., Nobrega, A. C., & Silva, B. M. (2015). Remote ischemic preconditioning delays fatigue development during handgrip exercise. Scand J Med Sci Sports, 25(3), 356-364. doi:10.1111/sms.12229 Baross, A. W., Wiles, J. D., & Swaine, I. L. (2013). Double-leg isometric exercise training in older men. Open Access J Sports Med, 4, 33-40. doi:10.2147/oajsm.s39375 Brito, M. V. H., Yasojima, E. Y., Machado, A. A., Silveira, M., Teixeira, R. K. C., Yamaki, V. N., & Costa, F. (2017). DIFFERENT PROTOCOLS OF POSTCONDITIONING DOES NOT ATTENUATE MESENTERIC ISCHEMIA-REPERFUSION INJURY AFTER SHORT-TERM REPERFUSION. 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Curr Hypertens Rep, 19(6), 51. doi:10.1007/s11906-017-0748-8 McGowan, C. L., Visocchi, A., Faulkner, M., Verduyn, R., Rakobowchuk, M., Levy, A. S., . . . MacDonald, M. J. (2007). Isometric handgrip training improves local flow-mediated dilation in medicated hypertensives. Eur J Appl Physiol, 99(3), 227-234. doi:10.1007/s00421-006-0337-z Millar, P. J., Bray, S. R., MacDonald, M. J., & McCartney, N. (2008). The hypotensive effects of isometric handgrip training using an inexpensive spring handgrip training device. J Cardiopulm Rehabil Prev, 28(3), 203-207. doi:10.1097/01.HCR.0000320073.66223.a7 Millar, P. J., Levy, A. S., McGowan, C. L., McCartney, N., & MacDonald, M. J. (2013). Isometric handgrip training lowers blood pressure and increases heart rate complexity in medicated hypertensive patients. Scand J Med Sci Sports, 23(5), 620-626. doi:10.1111/j.1600-0838.2011.01435.x Millar, P. J., MacDonald, M. J., Bray, S. R., & McCartney, N. (2009). 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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/92137 | - |
| dc.description.abstract | 背景：高血壓是現今社會中對全民健康具有極大威脅的問題之一，不良的血壓數值代表著健康的警訊，也是諸多心血管疾病的致病風險。過去的研究表明，不同型態的運動方式皆可達到降低血壓的目的，其中等長收縮訓練具有最大程度降低收縮壓的潛力。目的：本研究以降低前高血壓患者的血壓為目標，比較等長收縮訓練 (主動收縮) 與缺血預處理 (被動收縮) 對其效果的影響。方法：本研究招募20位成年男性(收縮壓：132.9 ± 4.4 mmHg；舒張壓：79.1 ± 5.5 mmHg)，隨機分配至控制組 (CON)、缺血預處理組 (IPC)、等長收縮運動組 (ISO)、混合組 (MIX)，進行連續五天的實驗介入，並觀察在介入後次最大運動測試中的血壓、心率、心率變異性變化。資料分析使用混合設計二因子變異數分析 (Two-way ANOVA, mixed design) ，以及成對樣本T檢定 (paired sample t test)，顯著水準設為p < .05。結果：經過連續五日介入後的收縮壓變化，缺血預處理組 (pre vs. post, 133.3 ± 4.9 mmHg vs. 125.2 ± 3.6 mmHg, p = .00, Cohen's d = 2.7)、等長收縮運動組 (pre vs. post, 132.5 mmHg ± 4.4 vs. 127.4 ± 4.1 mmHg, p = .00, Cohen's d = 2.1)、混合組 (pre vs. post, 132.5 ± 4.4 mmHg vs. 126.3 ± 3.1 mmHg, p = .00, Cohen's d = 2.2)，其中以缺血預處理組效果量最大。結論：連續五日缺血預處理以及等長收縮運動後，皆可改善患者血壓，並且能透過心率變異性看出副交感神經活性增加。本研究認為，上述兩種方式皆屬於改善血壓的非藥物治療方式，然而就執行的方便性及安全性而言，缺血預處理可能更加適合，因為被動收縮在安全上有更高的掌握性，並且器材也更簡便、更容易在居家由患者自己操作。 | zh_TW |
| dc.description.abstract | Background: Hypertension poses a significant public health threat, serving as a critical indicator of overall well-being and a contributory risk factor for various cardiovascular diseases. Previous research suggests that different modalities of exercise can effectively lower blood pressure, with isometric training demonstrating particular potential for reducing systolic pressure. Objectives: The present study aims to compare the effects of isometric contraction training (active contraction) and ischemic preconditioning (passive contraction) in reducing blood pressure among individuals with prehypertension. Methods: Twenty adult males (SBP: 132.9 ± 4.4 mmHg; DBP: 79.1 ± 5.5 mmHg) were recruited and randomly allocated into four groups: Control (CON), Ischemic Preconditioning (IPC), Isometric Exercise (ISO), and Mixed group (MIX). A five-day consecutive intervention was performed, followed by observations in submaximal exercise tests for blood pressure, heart rate, and heart rate variability. Data were analyzed using a two-way mixed-design ANOVA and paired sample t-tests, with a significance level set at p < .05. Results: Post-intervention systolic blood pressure changes indicated the greatest effect size in the IPC (pre vs. post, 133.3 ± 4.9 mmHg vs. 125.2 ± 3.6 mmHg, p = .00, Cohen's d = 2.7), followed by the ISO (pre vs. post, 132.5 ± 4.4 mmHg vs. 127.4 ± 4.1 mmHg, p = .00, Cohen's d = 2.1), and the MIX (pre vs. post, 132.5 ± 4.4 mmHg vs. 126.3 ± 3.1 mmHg, p = .00, Cohen's d = 2.2). Conclusion: Both ischemic preconditioning and isometric exercise were effective non-pharmacological approaches for improving healthier blood pressure. Increased parasympathetic activity was also evident through heart rate variability metrics. However, considering practicality and safety, ischemic preconditioning may be more suitable as it offers greater control over safety parameters and the convenience of home-based, self-administered intervention using simpler equipment. | en |
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| dc.description.provenance | Made available in DSpace on 2024-03-07T16:14:54Z (GMT). No. of bitstreams: 0 | en |
| dc.description.tableofcontents | 口試委員會審定書……………………………………………………………………I
誌謝………………………………………………………………………………… ..II 摘要…………………………………………………………………………………..III Abstract……………………………………………………………………………....IV List of figures…………………………………………………………………………VI List of tables………………………………………………………………………...VIII Chapter 1. Introduction 1.1 Background………………………………………………………………….. 1 1.2 Hypothesis…………………………………………………………………... 3 1.3 Objectives and importance……………………………………………………4 1.4 Limitations…………………………………………. .. ……………………...4 1.5 Operational definitions of terms 1.5.1 Prehypertension……………………………………………………….4 1.5.2 Ischemic preconditioning (IPC)……………………………………….5 1.5.3 Isometric exercise (ISO)………………………………………………5 1.5.4 MIX group (isometric exercise after IPC)……………………………5 1.5.5 Submaximal exercise test……………………………………………...5 1.5.6 Heart rate variability (HRV)…………………………………………..5 Chapter 2. Literature Review 2.1 Definition and clinical significance of hypertension…………………………8 2.2 Treatment of hypertension……………………………………………………8 2.3 Overview of ischemic preconditioning……………………………………...10 2.4 Overview of isometric training………………………………………………12 2.5 Effects of ischemic preconditioning on blood pressure……………………...12 2.6 Effects of isometric training on blood pressure……………………………...15 2.7 Summary…………………………………………………………………….18 Chapter 3. Research design 3.1 Participants………………………………………………………………….20 3.2 Experimental timing and setting…………………………………………….20 3.3 Experimental design 3.3.1 Independent variables………...………………….…………………..20 3.3.2 Dependent variables………...………………….………………...…..20 3.4 Experimental procedure 3.4.1 Experiment steps…………………….…………………………….…22 3.4.2 Experimental procedures………….…………………………….…...24 3.4.3 Data collection……………………………………………………….25 3.5 Research instrument…………………………………………………………26 3.6 Data processing and statistical analysis……………………………………...26 Chapter 4. Results 4.1 Basic information of participants……………………………………............28 4.2 Submaximal exercise test 4.2.1 Time to completion…………………………………………..............28 4.2.2 Submaximal exercise testing duration…………………….................29 4.2.3 Post-testing recovery period………………………………................33 4.3 Intervention period 4.3.1 Daily interventions…………………………………………..............39 4.3.2 Five-day continuous intervention period……………………..............42 4.4 Five-day interventional effects……………………………………................47 Chapter 5. Discussion and conclusion 5.1 Short term effects of ischemic preconditioning on blood pressure…………..50 5.2 Short term effects of isometric exercise on blood pressure………………….53 5.3 Short term effects of isometric exercise after IPC on blood pressure……….55 5.4 Heart rate variability, blood pressure, and the sympathetic and parasympathetic nervous systems……………………………………………………………..56 5.5 Conclusions and suggestions………………………………………………..57 Reference……………………………………………………………………………59 | - |
| dc.language.iso | en | - |
| dc.subject | 血流限制 | zh_TW |
| dc.subject | 高血壓非藥物治療 | zh_TW |
| dc.subject | 副交感神經活性 | zh_TW |
| dc.subject | 心率變異性 | zh_TW |
| dc.subject | 高血壓預防 | zh_TW |
| dc.subject | Non-Pharmacological Treatment for Hypertension | en |
| dc.subject | Hypertension Prevention | en |
| dc.subject | Heart Rate Variability | en |
| dc.subject | Blood Flow Restriction | en |
| dc.subject | Parasympathetic Activity | en |
| dc.title | 短期缺血預處理與等長收縮運動對前期高血壓患者的血壓影響 | zh_TW |
| dc.title | Effect of Short-Term Ischemic Preconditioning and Isometric Exercise for the Elevated Blood Pressure Response | en |
| dc.type | Thesis | - |
| dc.date.schoolyear | 112-1 | - |
| dc.description.degree | 碩士 | - |
| dc.contributor.coadvisor | 王鐘賢 | zh_TW |
| dc.contributor.coadvisor | Jong-Shyan Wang | en |
| dc.contributor.oralexamcommittee | 王鶴森 | zh_TW |
| dc.contributor.oralexamcommittee | Ho-Seng Wang | en |
| dc.subject.keyword | 血流限制,高血壓非藥物治療,副交感神經活性,心率變異性,高血壓預防, | zh_TW |
| dc.subject.keyword | Blood Flow Restriction,Non-Pharmacological Treatment for Hypertension,Parasympathetic Activity,Heart Rate Variability,Hypertension Prevention, | en |
| dc.relation.page | 65 | - |
| dc.identifier.doi | 10.6342/NTU202400420 | - |
| dc.rights.note | 同意授權(限校園內公開) | - |
| dc.date.accepted | 2024-02-06 | - |
| dc.contributor.author-college | 共同教育中心 | - |
| dc.contributor.author-dept | 運動設施與健康管理碩士學位學程 | - |
| 顯示於系所單位： | 運動設施與健康管理碩士學位學程 | |
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| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-112-1.pdf 授權僅限NTU校內IP使用（校園外請利用VPN校外連線服務） | 2.15 MB | Adobe PDF |
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