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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 趙福杉 | zh_TW |
dc.contributor.advisor | Fu-Shan Jaw | en |
dc.contributor.author | 張碩庭 | zh_TW |
dc.contributor.author | Shuo-Ting Chang | en |
dc.date.accessioned | 2024-01-26T16:35:00Z | - |
dc.date.available | 2024-03-01 | - |
dc.date.copyright | 2024-01-26 | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-01-22 | - |
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[2] A. Wassermann, S. Finn, and H. Axer, “Age-Associated Characteristics of Patients With Chronic Dizziness and Vertigo,” Journal of geriatric psychiatry and neurology, vol. 35, pp. 1-6, 2021. [3] L. Fernández, H. A. Breinbauer, and P. H. Delano, “Vertigo and Dizziness in the Elderly,” Front Neurology, vol. 6, no. 144, pp. 1-6, 2015. [4] P. F. Smith, “The vestibular system and cognition. Current Opinion,” Neurology, vol. 30, no. 1, pp.84-89, 2017. [5] J. G. Nicholls, A. R. Martin, B. G. Wallace, and P. A. Fuchs, “Auditory and Vestibular Sensation,” in From neuron to brain, Sunderland MA, Sinauer Associates, pp. 453-473, 2011. [6] M. Strupp and T. Brandt, “Diagnosis and treatment of vertigo and dizziness,” Dtsch Arztebl Int., vol. 105, no. 10, pp. 173-180, 2008. [7] C. Dorbeau, K. Bourget, L. Renard, C. Calais, and D. Bakhos, “Vestibular evoked myogenic potentials,“ European Annals of Otorhinolaryngology, Head and Neck Diseases, vol. 138, issue 6, pp.483-488, 2021. [8] S. M. Rosengren, J. G. Colebatch, A. S. Young, S. Govender, and M. S. Welgampola, “Vestibular evoked myogenic potentials in practice: Methods, pitfalls and clinical applications,” Clinical Neurophysiology Practice, vol. 4, pp.47-68, 2019. [9] 王守仁。「短迴旋音與機械振動刺激衍生之眼性及頸性前庭誘發肌性電位」,博士論文。國立臺灣大學醫學工程學研究所,2012。〈https://doi.org/10.6342/NTU.2012.11011〉。 [10] 林奎佑。「振動、加速度、及共振對於耳石反射系的影響」。博士論文,國立臺灣大學醫學工程學研究所,2021。〈https://doi.org/10.6342/NTU202100339〉。 [11] 陳子揚。「頭部假體模型之加速度變化分析」。碩士論文,國立臺灣大學醫學工程學研究所,2019。〈https://doi.org/10.6342/NTU201901000〉。 [12] K. Ueda, I. Ota, T. Yamanaka, and T. Kitahara, “The Impact of the COVID-19 Pandemic on Follow-Ups for Vertigo/Dizziness Outpatients,” Ear, nose, & throat journal, vol. 100, no. 2, pp. 163-168, 2021. [13] S. M. Rosengren, N. P. McAngus Todd, and J. G. Colebatch, “Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound,” Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, vol. 116, no. 8, pp. 1938-48, 2005. [14] N. L. Greenwalt, J. N. Patterson, A. I. Rodriguez, D. Fitzpatrick, K. R. Gordon, and K. L. Janky, “Bone Conduction Vibration Vestibular Evoked Myogenic Potential (VEMP) Testing: Reliability in Children, Adolescents, and Young Adults,” Ear Hear, vol. 42, no.2, pp. 355-363, 2021. [15] B. Håkansson, K. J. Fredén Jansson, T. Tengstrand, L. Johannsen, M. Eeg-Olofsson, C. Rigato, E. Dahlström, and S. Reinfeldz, "VEMP using a new low-frequency bone conduction transducer," Med Devices, vol. 11, pp. 301-312, 2018. [16] T. R. Silva, M. A. R. Santos, L. M. de Resende, L. Labanca, J. F. de Morais Caporali, M. R. de Sousa, and D. U. Gonçalves, “Applications of vestibular-evoked myogenic potentials: a systematic literature review,” Audiology Communication Research, vol. 24, 2019. [17] J. Dlugaiczyk, “Evidence-based diagnostic use of VEMPs,” HNO, vol. 68, no. 2, pp. 69–78, 2020. [18] C. G. Clinard, E. G. Piker, A. P. Thorne, E. N. Surface, A. E. Anderson, V. A. Beacham, M. C. Crouse, V. H. Whitney, and R. A. Depaolis, “Maximum Output and Low-Frequency Limitations of B71 and B81 Clinical Bone Vibrators: Implications for Vestibular Evoked Potentials,” Ear and hearing, vol. 41, no. 4, pp. 847-854, 2020. [19] K. Y. Lin, F. S. Jaw, and Y. H. Young, “A model study of resonance effect on ocular vestibular-evoked myogenic potential,” Journal of the Formosan Medical Association, vol. 121, no. 1, pp. 66-72, 2022. [20] M. Oka, K. Ichijo, K. Koda, T. Kamogashira, M. Kinoshita, K. Igarashi, T. Kawahara, I. Takashima, T. Yamasoba, and C. Fujimoto, “Preceding Balance Disorders Affect Vestibular Function in Persistent Postural-Perceptual Dizziness,” Journal of Clinical Medicine, vol. 12, no. 7, p. 2589, 2023. [21] A. Eroglu, “RF Amplifier Classifications,” in Introduction to RF Power Amplifier Design and Simulation, Boca Raton, CRC Press, pp. 25-45, 2016. [22] B. Lütkenhöner, “What the electrical impedance can tell about the intrinsic properties of an electrodynamic shaker,” PLoS ONE, vol. 12, no. 3, pp. 174-184, 2017. [23] M. Maheu, J. M. Alvarado-Umanzor, A. Delcenserie, and F. Champoux, “The Clinical Utility of Vestibular-Evoked Myogenic Potentials in the Diagnosis of Ménière’s Disease,” Frontiers in Neurology, vol. 8, no. 415, 2017. [24] “Power Amplifier Type 2718,” Bksv.com. [Online]. Available: https://www.bksv.com/en/instruments/vibration-testing-equipment/vibration-amplifiers/exciters/power-amplifier-type-2718. [Accessed: 12-Dec-2023]. [25] “SmartVEMP,” Intelligenthearingsystems.com. [Online]. Available: https://ihsys.info/site/en/diagnostics/smartep/smartvemp. [Accessed: 12-Dec-2023]. [26] H. G. MacDougall, J. Holden, S. M. Rosengren, and E. Chiarovano, “μVEMP: A Portable Interface to Record Vestibular Evoked Myogenic Potentials (VEMPs) With a Smart Phone or Tablet,” Front Neurol, vol. 9, no. 543, 2018. | - |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/91455 | - |
dc.description.abstract | 人體平衡維持機制主要包含了前庭系統、視覺系統和本體感覺系統,而當前庭系統功能異常時,人體的平衡覺隨之出現問題,繼而肇生眩暈症。眩暈為臨床上常見的病症,全球約有兩至三成的人曾經歷眩暈症,且復發率高達四成,雖然各年齡層的人口都可能受眩暈症所苦,但其中老年患者的比例較高,且症狀隨著年紀增長而更加嚴重,而眩暈症發作時導致年長者跌倒甚至成為65歲以上人口意外事故的主要死因。
為了評估前庭功能和判斷眩暈症成因,目前臨床上普遍使用前庭誘發肌電位檢查(Vestibular Evoked Myogenic Potential, VEMP)。隨著人口高齡化的現象,眩暈症老年患者的比例上升,且由於眩暈症的高復發率,患者應定期回診檢查,避免過久的回診時間讓病程惡化。考量到以上因素,若能將VEMP檢查優化或提升便利性,甚至整合其至居家醫療,則可解決行動不便或居住地偏遠的老年患者族群就診上的困難,或是高齡患者可能因考量到感染疾病的風險而不願前往醫療院所導致延遲就醫的情況發生。 為實現將VEMP檢查整合至居家醫療的願景,在參考過去實驗室相關研究計畫成果後,本研究期望將VEMP檢查需使用到的功率放大器設計為可攜式,期在安全驅動現今VEMP檢查臨床所使用的小型振動器Type 4810 Mini-shaker之前提下,能完成VEMP檢查便利性的提升及相關流程的改善,讓病患得以在自家環境中接受VEMP檢查,減少前往醫療機構的需求。 本研究成功開發應用於VEMP檢查之可攜式功率放大器系統,不需插電使用,且裝置利用交換式電源供電,讓使用者得以僅使用單顆電池,而不需消耗兩組電池,即可提供功率放大器穩定的正負電源。本研究透過電路設計達到低功耗之目的,裝置靜態電流為1.6 mA,並具有體積小、重量輕等特點,符合可攜式之需求,解決了市售功率放大器因體積龐大受限於醫院環境且售價高的缺點,使VEMP檢查得以朝居家醫療整合、甚至社區醫療或偏鄉義診的願景邁進。 | zh_TW |
dc.description.abstract | The mechanism of maintaining human body balance is mainly composed of the vestibular system, visual system and proprioception system. If there is a vestibular dysfunction, problems consequently arise in our sense of balance, resulting in vertigo afterwards. Vertigo is a common clinical disease, with twenty to thirty percent of people worldwide having been through it, and the recurrence rate is up to forty percent. Although people of all ages may suffer from vertigo, the proportion of elderly patients is higher. Moreover, the symptom gets more serious with age, and falling down due to vertigo even becomes the main cause of accidental death in people aged 65 and older.
To evaluate the function of vestibular system and to determine the cause of vertigo, vestibular evoked myogenic potential(VEMP) testing is generally used in clinics. With the phenomenon of population aging, the proportion of elderly patients with vertigo has increased, and because of the high recurrence rate of vertigo, patients should have regular follow-up appointments, preventing the condition from deteriorating owing to overlong follow-up duration. In view of the above factors, if we can optimize VEMP testing, improve its convenience, or even integrate it into home medical care, we are able to resolve the difficulty of elderly patients going to the hospital on account of their disabilities or remote residences, or the delay in treatment resulting from aged patients taking the risk of infection into consideration and hence unwilling to go to the hospital. For the purpose of realizing the vision of integrating VEMP testing into home medical care, after referring to the previous laboratory research projects, this study expects to make the power amplifier in VEMP testing into a portable device, hoping to improve the convenience of VEMP testing together with relevant procedures under the premise of safely driving the Type 4810 Mini-shaker used in VEMP testing nowadays, which enables patients to take VEMP testing in their home environment and reduces the need for going to health facilities. A portable power amplifier system for VEMP testing has been successfully developed in this study, being no need for plugging in, and furthermore, the device is powered by a switching power supply, allowing users to provide stable positive and negative power for the power amplifier with only one battery instead of two. This study achieves the aim of low power through circuit design, and the quiescent current of the device is 1.6 mA, possessing features of small-sized and lightweight as well, which meets the requirement for portability and solves the drawback of power amplifier on the market being limited to hospital environment because of its large size, letting VEMP testing be able to moving toward the vision of integrating into home or community medical care, or even rural health clinics. | en |
dc.description.provenance | Submitted by admin ntu (admin@lib.ntu.edu.tw) on 2024-01-26T16:35:00Z No. of bitstreams: 0 | en |
dc.description.provenance | Made available in DSpace on 2024-01-26T16:35:00Z (GMT). No. of bitstreams: 0 | en |
dc.description.tableofcontents | 誌謝 i
中文摘要 ii Abstract iii 目次 v 圖目次 vii 表目次 ix 第一章、緒論 1 1.1 研究背景 1 1.2 研究動機及目的 5 第二章、系統介紹 6 2.1 系統架構 6 2.2 設計考量 7 2.2.1 VEMP刺激模式與振動器之選擇 7 2.2.2 刺激信號頻率與振幅大小之考量 8 2.2.3 功率放大器之設計考量 8 2.2.4 交換式電源設置之考量 9 2.3 元件與儀器之選擇考量 10 2.3.1 運算放大器 10 2.3.2 達靈頓電晶體 10 2.3.3 交換式穩壓器 10 第三章、研究結果 12 3.1 Type 4810 Mini-shaker量測 12 3.2 可攜式功率放大器電路設計 13 3.2.1 減少交越失真 13 3.2.2 改善頻率響應 16 3.2.3 偏壓電路設計 18 3.3 功率放大器實際量測結果 20 3.4 單電池交換式雙電源電路設計 22 3.4.1 升壓和負電壓電路設計 22 3.4.2 輸出電源之濾波器 24 3.5 單電池交換式雙電源實際量測結果 25 3.6 系統外觀 27 第四章、討論 28 4.1 市售功率放大器系統比較 28 4.2 選擇適當運算放大器之重要性 29 4.3 功率放大器偏壓電路電源供應端電阻對靜態電流的影響 29 4.4 選擇適當交換式穩壓器之重要性 30 4.5 探討Type 4810 Mini-shaker文獻之量測方式 31 4.6 居家VEMP檢查之應用 32 第五章、結論 34 參考文獻 35 | - |
dc.language.iso | zh_TW | - |
dc.title | 可攜式功率放大器應用於前庭誘發肌電位檢查 | zh_TW |
dc.title | Portable Power Amplifier for Vestibular Evoked Myogenic Potential Testing | en |
dc.type | Thesis | - |
dc.date.schoolyear | 112-1 | - |
dc.description.degree | 碩士 | - |
dc.contributor.coadvisor | 林奎佑 | zh_TW |
dc.contributor.coadvisor | Kuei-You Lin | en |
dc.contributor.oralexamcommittee | 高瑀絜;陳芝萍;陳光萱;曾乙立 | zh_TW |
dc.contributor.oralexamcommittee | Yu-Chieh Kao;Chih-Ping Chen;Kuang-Hsuan Chen;Yi-Li Tseng | en |
dc.subject.keyword | 前庭系統,前庭誘發肌電位檢查,可攜式功率放大器,交換式電源, | zh_TW |
dc.subject.keyword | vestibular system,VEMP,portable power amplifier,switching power supply, | en |
dc.relation.page | 37 | - |
dc.identifier.doi | 10.6342/NTU202400077 | - |
dc.rights.note | 同意授權(限校園內公開) | - |
dc.date.accepted | 2024-01-23 | - |
dc.contributor.author-college | 工學院 | - |
dc.contributor.author-dept | 醫學工程學系 | - |
顯示於系所單位: | 醫學工程學研究所 |
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