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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 花茂棽(Mau-Sun Hau) | |
dc.contributor.author | Yu-Hsuan Sun | en |
dc.contributor.author | 孫鈺玹 | zh_TW |
dc.date.accessioned | 2021-05-11T05:15:07Z | - |
dc.date.available | 2021-01-15 | |
dc.date.available | 2021-05-11T05:15:07Z | - |
dc.date.copyright | 2019-01-15 | |
dc.date.issued | 2019 | |
dc.date.submitted | 2019-01-11 | |
dc.identifier.citation | Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., . . . Phelps, C. H. (2011). The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement, 7, 270-279. doi:10.1016/j.jalz.2011.03.008
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dc.identifier.uri | http://tdr.lib.ntu.edu.tw/handle/123456789/886 | - |
dc.description.abstract | 背景 具有主觀認知衰退(Subjective Cognitive Decline)的成年人,被認為是未來可能轉化為輕度認知障礙(Mild Cognitive Impairment)和阿茲海默型失智症(Alzheimer’s Disease)的群體。近期研究指出,主觀認知衰退個體在與自主感受和後設記憶有關的腦區,有異常表現。因此,本研究旨在事件記憶中使用知感作業(Feeling-of-Knowing)來檢測主觀認知衰退個體在後設記憶上的表現,是否與輕度認知障礙和阿茲海默型失智症的病人相似,以及其表現是否受視覺或聽覺作業型態影響。
方法 本研究納入年齡範圍在50至85歲的八十八位受試者,包含健康控制組、主觀認知衰退組、輕度認知障礙組以及阿茲海默型失智症組。每位受試者接受視覺和聽覺事件記憶下的知感作業,以及神經心理測驗套組。 結果 在視覺知感測驗中,主觀認知衰退組的分數表現與健康控制組、輕度認知障礙組間無顯著差異,僅與阿茲海默型失智症組的分數有顯著差異。而健康控制組的表現顯著好於輕度認知障礙組、阿茲海默型失智症組。在聽覺知感測驗中,健康控制組與主觀認知衰退組間無顯著差異,但兩組的表現皆與兩組病人組有顯著差異。 結論 根據本研究在記憶監控功能上的結果,具主觀認知衰退的個體可能處於健康老化與病態老化之間的階段。建議未來針對此議題的研究可納入大量樣本與不同的記憶測驗。 | zh_TW |
dc.description.abstract | Background Subjective Cognitive Decline (SCD) in cognitively unimpaired individuals has been recognized as a possible sign predicting future decline to mild cognitive impairment (MCI) and Alzhemier’s Disease (AD). Individuals with SCD showed atypical findings in brain regions that are associated with subjective feeling and memory monitoring. Thus, the current study aimed to examine whether the performance pattern on the episodic memory feeling of knowing (FOK) paradigm measures in individuals with SCD is comparable to that of patients with MCI and AD, and whether individuals with SCD exhibit different performance pattern on visual- and auditory-modality FOK tests.
Methods A total of 88 adult participants (aged 50 to 85), including 4 groups, healthy control (HC), SCD, MCI and AD, were recruited in the present study. Each participant received visually and aurally episodic memory feeling-of-knowing (FOK) paradigm and a battery of neuropsychological tests. Results On the visual FOK test, the performance scores were not significantly different between SCD and HC, and between SCD and MCI while the score differences between SCD and AD were remarkable. The HC’s performance significantly overpowered the two patient groups. On the auditory FOK test, the performance scores between participants of HC and SCD were not significantly different while the scores of both HC and SCD were significantly different from the two patients groups. Conclusion. Based on the present results of meta-memory functioning study, we suggest that individuals with SCD may be placed on the stage between health aging and pathological aging. However, further study on a large scale and different memory tests on this issue is necessary. | en |
dc.description.provenance | Made available in DSpace on 2021-05-11T05:15:07Z (GMT). No. of bitstreams: 1 ntu-108-R04227201-1.pdf: 696944 bytes, checksum: 35071573fde47c97459fe6b01ee5e9fb (MD5) Previous issue date: 2019 | en |
dc.description.tableofcontents | Abstract………………………………………………………………………….….. 1
Introduction…………………………………………………………………….…... 4 Methods………………………………………………………………………….…. 10 Participants………………………………………………………………….…. 10 Criteria for groups………………………………………………………….….. 11 FOK paradigm……………………………………………………………….… 13 Neurocognitive measures………………………………………………….… 14 Data collection……………………………………………………………….… 16 Statistical analyses……………………………………………………………... 16 Results…………………………………………………………………………….... 17 Demogrphic characteristics……………………………………………………. 17 FOK paradigm test performances……………………………………………. 18 Neurocognitive performances…………………………………………………. 23 FOK judgment and neurocognitive performances……………………………. 24 Discussion………………………………………………………………………… 26 References………………………………………………………………………….. 33 Tables………………………………………………………………………………. 51 Figures…………………………………………………………………………....... 58 | |
dc.language.iso | en | |
dc.title | 主觀認知缺損個體在視覺和聽覺事件記憶上的知感能力 | zh_TW |
dc.title | Visual- and Auditory-Based Episodic Memory Feeling-of-Knowing in Individuals with Subjective Cognitive Decline | en |
dc.date.schoolyear | 107-1 | |
dc.description.degree | 碩士 | |
dc.contributor.coadvisor | 張玉玲(Yu-Ling Chang) | |
dc.contributor.oralexamcommittee | 邱銘章,楊啟正 | |
dc.subject.keyword | 主觀認知缺損,知感,後設記憶,事件記憶,阿茲海默症,輕度認知障礙, | zh_TW |
dc.subject.keyword | subjective cognitive decline,feeling-of-knowing,memory monitoring,episodic memory,Alzheimer’s disease,mild cognitive impairment, | en |
dc.relation.page | 58 | |
dc.identifier.doi | 10.6342/NTU201900062 | |
dc.rights.note | 同意授權(全球公開) | |
dc.date.accepted | 2019-01-11 | |
dc.contributor.author-college | 理學院 | zh_TW |
dc.contributor.author-dept | 心理學研究所 | zh_TW |
顯示於系所單位: | 心理學系 |
文件中的檔案:
檔案 | 大小 | 格式 | |
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ntu-108-1.pdf | 680.61 kB | Adobe PDF | 檢視/開啟 |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。