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  1. NTU Theses and Dissertations Repository
  2. 工學院
  3. 醫學工程學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/87784
完整後設資料紀錄
DC 欄位值語言
dc.contributor.advisor趙福杉zh_TW
dc.contributor.advisorFu-Shan Jawen
dc.contributor.author陳建華zh_TW
dc.contributor.authorChien-Hua Chenen
dc.date.accessioned2023-07-19T16:28:36Z-
dc.date.available2023-11-09-
dc.date.copyright2023-07-19-
dc.date.issued2023-
dc.date.submitted2023-05-01-
dc.identifier.citation1. Gore, S. and A. Yeung, The "inside out" transforaminal technique to treat lumbar spinal pain in an awake and aware patient under local anesthesia: results and a review of the literature. Int J Spine Surg, 2014. 8.
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4. Hagan, M.J., et al., Navigation Techniques in Endoscopic Spine Surgery. Biomed Res Int, 2022. 2022: p. 8419739.
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6. Suk, J.I., F.O. Walker, and M.S. Cartwright, Ultrasonography of peripheral nerves. Curr Neurol Neurosci Rep, 2013. 13(2): p. 328.
7. Zander, D., et al., Ultrasound Image Optimization ("Knobology"): B-Mode. Ultrasound Int Open, 2020. 6(1): p. E14-e24.
8. Entrekin, R.R., et al., Real-time spatial compound imaging: application to breast, vascular, and musculoskeletal ultrasound. Semin Ultrasound CT MR, 2001. 22(1): p. 50-64.
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11. Raymond, C.A., Brain, spine surgeons say yes to ultrasound. Jama, 1986. 255(17): p. 2258-9, 2262.
12. Vasudeva, V.S., et al., Use of Intraoperative Ultrasound During Spinal Surgery. Global Spine J, 2017. 7(7): p. 648-656.
13. Dohrmann, G.J. and J.M. Rubin, Intraoperative ultrasound imaging of the spinal cord: syringomyelia, cysts, and tumors--a preliminary report. Surg Neurol, 1982. 18(6): p. 395-9.
14. Wu, R., X. Liao, and H. Xia, Radiation Exposure to the Surgeon During Ultrasound-Assisted Transforaminal Percutaneous Endoscopic Lumbar Discectomy: A Prospective Study. World Neurosurg, 2017. 101: p. 658-665.e1.
15. Chang, K.V., W.T. Wu, and L. Özçakar, Ultrasound-Guided Interventions of the Cervical Spine and Nerves. Phys Med Rehabil Clin N Am, 2018. 29(1): p. 93-103.
16. Zhang, M., et al., Ultrasound-guided transforaminal percutaneous endoscopic lumbar discectomy: a new guidance method that reduces radiation doses. Eur Spine J, 2019. 28(11): p. 2543-2550.
17. Zhao, Y., et al., Guided Punctures with Ultrasound Volume Navigation in Percutaneous Transforaminal Endoscopic Discectomy: A Technical Note. World Neurosurg, 2018. 119: p. 77-84.
18. Ahn, Y., Endoscopic spine discectomy: indications and outcomes. Int Orthop, 2019. 43(4): p. 909-916.
19. Chang, K.V., et al., Sonoanatomy of the spine: a comprehensive scanning protocol from cervical to sacral region. Med Ultrason, 2019. 21(4): p. 474-482.
20. Quillo-Olvera, J., G.X. Lin, and J.S. Kim, Percutaneous endoscopic cervical discectomy: a technical review. Ann Transl Med, 2018. 6(6): p. 100.
21. Dietrich, C.F., et al., Ultrasound of the pleurae and lungs. Ultrasound Med Biol, 2015. 41(2): p. 351-65.
22. Zhang, M.B., et al., Ultrasound guidance for transforaminal percutaneous endoscopic lumbar discectomy may prevent radiation exposure: A case report. World J Clin Cases, 2019. 7(10): p. 1161-1168.
23. Tai, C.-T., et al., Transforaminal Endoscopic Lumbar Discectomy with Foraminoplasty for Down-migrated Disc Herniation: A Single-center Observational Study. J Minim Invasive Spine Surg Tech, 2022. 7(1): p. 9-15.
24. Chen, C.H., et al., Ultrasound Guidance for Full Endoscopic Spinal Surgery: A Technical Note. World Neurosurg, 2022. 162: p. 59-65.
25. Lin, T.Y., et al., Ultrasonography for the diagnosis of carpal tunnel syndrome: an umbrella review. J Neurol, 2022. 269(9): p. 4663-4675.
26. Pourmemari, M.H., et al., Carpal tunnel release: Lifetime prevalence, annual incidence, and risk factors. Muscle Nerve, 2018. 58(4): p. 497-502.
27. Chiou, H.J., et al., Cubital tunnel syndrome: diagnosis by high-resolution ultrasonography. J Ultrasound Med, 1998. 17(10): p. 643-8.
28. Buntragulpoontawee, M., et al., The Effectiveness and Safety of Commonly Used Injectates for Ultrasound-Guided Hydrodissection Treatment of Peripheral Nerve Entrapment Syndromes: A Systematic Review. Front Pharmacol, 2020. 11: p. 621150.
29. Carlson, H., et al., Current options for nonsurgical management of carpal tunnel syndrome. Int J Clin Rheumtol, 2010. 5(1): p. 129-142.
30. Lin, C.P., et al., Regenerative Injections Including 5% Dextrose and Platelet-Rich Plasma for the Treatment of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis. Pharmaceuticals (Basel), 2020. 13(3).
31. Wang, J.C., et al., Ultrasound-Guided Triamcinolone Acetonide Hydrodissection for Carpal Tunnel Syndrome: A Randomized Controlled Trial. Front Med (Lausanne), 2021. 8: p. 742724.
32. Vetrano, I.G., G. Devigili, and V. Nazzi, Minimally Invasive Carpal Tunnel Release: A Technical Note and a 20-Year Retrospective Series. Cureus, 2022. 14(1): p. e21426.
33. Rojo-Manaute, J.M., et al., Ultra-minimally invasive sonographically guided carpal tunnel release: anatomic study of a new technique. J Ultrasound Med, 2013. 32(1): p. 131-42.
34. Henning, P.T., et al., Minimally Invasive Ultrasound-Guided Carpal Tunnel Release: Preliminary Clinical Results. J Ultrasound Med, 2018. 37(11): p. 2699-2706.
35. Sonoo, M., et al., Nerve conduction studies and EMG in carpal tunnel syndrome: Do they add value? Clin Neurophysiol Pract, 2018. 3: p. 78-88.
36. Werner, R.A. and M. Andary, Electrodiagnostic evaluation of carpal tunnel syndrome. Muscle Nerve, 2011. 44(4): p. 597-607.
37. Torres-Costoso, A., et al., Accuracy of Ultrasonography for the Diagnosis of Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis. Arch Phys Med Rehabil, 2018. 99(4): p. 758-765.e10.
38. Petrover, D., et al., Ultrasound-Guided Surgery for Carpal Tunnel Syndrome: A New Interventional Procedure. Semin Intervent Radiol, 2018. 35(4): p. 248-254.
39. Stütz, N., et al., Revision surgery after carpal tunnel release--analysis of the pathology in 200 cases during a 2 year period. J Hand Surg Br, 2006. 31(1): p. 68-71.
40. Hsiao, M.Y., et al., Dynamic Ultrasonography of the Intra-Articular Long Head Biceps Tendon and Superior Labrum. Am J Phys Med Rehabil, 2016. 95(11): p. e183-e184.
41. Chang, K.V., et al., Clinical Tests of the Shoulder: Accuracy and Extension Using Dynamic Ultrasound. Am J Phys Med Rehabil, 2020. 99(2): p. 161-169.
42. Lin, C.Y., et al., Quantitative Analysis of Dynamic Subacromial Ultrasonography: Reliability and Influencing Factors. Front Bioeng Biotechnol, 2022. 10: p. 830508.
43. Chen, C.H., et al., Dynamic ultrasound for evaluating the adequacy of median nerve decompression following minimally invasive carpal tunnel release: technical innovation and case study. Heliyon, 2023. 9(1): p. e13107.
44. Chang, K.V., W.T. Wu, and L. Özçakar, Ultrasound imaging and guidance in peripheral nerve entrapment: hydrodissection highlighted. Pain Manag, 2020. 10(2): p. 97-106.
45. Lo, I.N., et al., Dynamic Ultrasound Assessment of Median Nerve Mobility Changes Following Corticosteroid Injection and Carpal Tunnel Release in Patients With Carpal Tunnel Syndrome. Front Neurol, 2021. 12: p. 710511.
46. Chin, B., et al., Efficient Imaging: Examining the Value of Ultrasound in the Diagnosis of Traumatic Adult Brachial Plexus Injuries, A Systematic Review. Neurosurgery, 2018. 83(3): p. 323-332.
47. Hsu, P.C., et al., Sonographic Pearls for Imaging the Brachial Plexus and Its Pathologies. Diagnostics (Basel), 2020. 10(5).
48. Zhang, M., et al., Methylcobalamin: a potential vitamin of pain killer. Neural Plast, 2013. 2013: p. 424651.
49. Nishimoto, S., et al., Methylcobalamin promotes the differentiation of Schwann cells and remyelination in lysophosphatidylcholine-induced demyelination of the rat sciatic nerve. Front Cell Neurosci, 2015. 9: p. 298.
50. Gan, L., et al., Restorative effect and mechanism of mecobalamin on sciatic nerve crush injury in mice. Neural Regen Res, 2014. 9(22): p. 1979-84.
51. Xiong, Z.L., et al., Based on proteomics to explore the mechanism of mecobalamin promoting the repair of injured peripheral nerves. Can J Physiol Pharmacol, 2022. 100(6): p. 562-572.
52. Wang, H., et al., Oral vitamin B(12) versus intramuscular vitamin B(12) for vitamin B(12) deficiency. Cochrane Database Syst Rev, 2018. 3(3): p. Cd004655.
53. Chen, C.H., et al., Ultrasound-Guided Perineural Vitamin B12 Injection for Brachial Plexus Injury: A Preliminary Study. Cell Transplant, 2023. 32: p. 9636897231167213.
54. Sun, H., et al., Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor. Arch Med Sci, 2012. 8(5): p. 924-30.
55. Alavekios, D.A., et al., Longitudinal analysis of effects of operator experience on accuracy for ultrasound detection of supraspinatus tears. J Shoulder Elbow Surg, 2013. 22(3): p. 375-80.
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dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/87784-
dc.description.abstract背景:
傳統上,在進行脊椎及周邊神經微創手術時並不會使用超音波作為導引工具,而是用X光。然而X光並無法清楚顯像軟組織,重要的軟組織結構存在受損的風險。此外,周邊神經手術減壓是否徹底傳統上也沒有一個好的影像評估工具。透過術中超音波的應用,軟組織結構可以清楚辨識,進而提高微創手術的精準度與安全度。透過動態超音波的應用,更可用以確認周邊神經減壓是否充足。因此,本研究闡明進行微創手術時的超音波應用技術,以期增進病患福祉。

方法:
對於應用超音波於脊椎微創手術,可用解剖結構的特異性來定位脊椎節段。運用超音波來顯示脊椎周圍的重要軟組織結構,包括食道、神經根、椎動脈、頸動脈、肺臟表面及肋膜、腸道、腎臟等,藉此避免這些重要結構的穿刺損傷。進行微創周邊神經減壓手術時,可運用動態超音波顯示周邊神經活動的狀態,藉此確保神經的減壓足夠。高解析超音波可清楚顯示頸椎神經根及周邊神經,甚至連神經裡的數個神經束都可清楚呈現,有助於神經病兆的評估,透過超音波導引更可以精確地將營養送到神經周圍以促進神經修復。

結果:
在脊椎及周邊神經微創手術使用超音波有助減少輻射暴露, 提高成功穿刺率 , 預防X光無法顯像的軟組織器官受到傷害。透過動態超音波,更可用以確保周邊神經減壓足夠。
結論:
超音波可以輔助微創手術的進行,有助於提升微創手術的精準度與安全性,希望透過此研究協助醫師熟稔超音波於微創手術的應用技術,進而增進病患福祉。
zh_TW
dc.description.abstractBackground:
Traditionally, ultrasound is not used as a guidance tool for minimally invasive spine and peripheral nerve surgeries, instead, X-ray is used. However, X-rays cannot clearly image soft tissue structures, which increases the risk of damage to important soft tissue structures. In addition, there is no good imaging assessment tool for evaluating the completeness of peripheral nerve decompression surgery. The application of intraoperative ultrasound can clearly identify soft tissue structures, thereby improving the accuracy and safety of minimally invasive surgery. Using dynamic ultrasound, it can also be used to confirm whether peripheral nerve decompression is sufficient. Therefore, this study elucidates the application of ultrasound in minimally invasive surgery to improve patient welfare.
Methods:
In applying ultrasound to minimally invasive spine surgery, the specific anatomical structures of spine can be used to locate the spinal level. Ultrasound is used to display important soft tissue structures surrounding the spine, including the esophagus, nerve roots, vertebral arteries, carotid arteries, lung surfaces and pleura, intestines, kidneys, etc., to avoid puncture damage to these important structures. During minimally invasive peripheral nerve decompression surgery, dynamic ultrasound can be used to display the status of peripheral nerve movement, thereby ensuring that nerve decompression is sufficient. High-resolution ultrasound can clearly display cervical nerve roots and peripheral nerves, even the fascicles within the nerve, which can help assess nerve pathology. Through ultrasound guidance, nutrients can be accurately delivered to the nerve periphery to promote nerve regeneration.
Results:
The use of ultrasound in minimally invasive spine and peripheral nerve surgery can reduce radiation exposure, improve successful puncture rate, and prevent soft tissue organ damage that cannot be imaged by X-rays. Through dynamic ultrasound, it can also be used to confirm whether peripheral nerve decompression is sufficient.
Conclusion:
Ultrasound can assist in the conduct of minimally invasive surgery, improving accuracy and safety. We hope that through this study, physicians will become more proficient in the application of ultrasound in minimally invasive surgery, thereby improving patient welfare.
en
dc.description.provenanceSubmitted by admin ntu (admin@lib.ntu.edu.tw) on 2023-07-19T16:28:36Z
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dc.description.tableofcontentsTable of Contents
口試委員會審定書…………………………………………………… i
序言及誌謝…………………………………………………………… ii
中文摘要………………………………………………………………iii
英文摘要………………………………………………………………v
Table of Contents………………………………………………………viii
List of Figures………………………………………………………xi
List of Tables…………………………………………………………xiv
Chapter 1: General Background…………………………………………1
Chapter 2: Basic Concepts and Settings of Ultrasound…………………6
2.1 Physics of Ultrasound………………………………………………6
2.2 Ultrasound imaging of peripheral nerves……………………………9
2.3 Ultrasound setting of dynamic range for imaging peripheral nerves and spine…………………………………………………………………11
2.4 Spatial compound imaging of ultrasound……………………………13
2.5 Ultrasound frequency setting for imaging of peripheral nerves and spine………………………………………………………………………16
2.6 Doppler mode and its significance……………………………………18
Chapter 3: Application of ultrasound in endoscopic spine surgeries……19
3.1 Introduction…………………………………………………………19
3.2 Application of ultrasound in cervical endoscopic spine surgery……23
3.3 Application of ultrasound in thoracic endoscopic spine surgery……28
3.4 Application of ultrasound in lumbar endoscopic spine surgery……30
3.5 Conclusion……………………………………………………34
Chapter 4: Ultrasound-facilitated carpal tunnel release: dynamic ultrasound to confirm the adequacy of median nerve decompression………………35
4.1 Introduction…………………………………………………………35
4.2 Ultrasound anatomy of carpal tunnel…………………………………37
4.3 EMG/NCV versus Ultrasound evaluation of carpal tunnel syndrome…39
4.4 Demonstrative cases…………………………………………………41
4.5 Technical innovation…………………………………………………44
4.6 Discussion……………………………………………………………49
4.7 Conclusion……………………………………………………………51
Chapter 5: Ultrasound-guided perineural vitamin B12 administration for brachial plexus injury……………………………………………………52
5.1 Introduction…………………………………………………………52
5.2 Vitamin B12 (methylcobalamin) and its role in facilitation of nerve regeneration………………………………………………………………55
5.3 Clinical cases………………………………………………………57
5.4 Technical note……………………………………………………58
5.5 Discussion…………………………………………………………59
5.6 Conclusion…………………………………………………………61
Chapter 6: Conclusion…………………………………………………64
References……………………………………………………………65
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dc.language.isoen-
dc.subject臂神經叢zh_TW
dc.subject超音波zh_TW
dc.subject內視鏡脊椎手術zh_TW
dc.subject椎間盤zh_TW
dc.subject微創手術zh_TW
dc.subject正中神經zh_TW
dc.subjectendoscopic spine surgeryen
dc.subjectmedian nerveen
dc.subjectminimally invasive surgeryen
dc.subjectintervertebral discen
dc.subjectultrasounden
dc.subjectbrachial plexusen
dc.title超音波於脊椎及周邊神經微創手術的的應用zh_TW
dc.titleApplication of Ultrasound in minimally invasive surgeries for spine and peripheral nervesen
dc.typeThesis-
dc.date.schoolyear111-2-
dc.description.degree博士-
dc.contributor.oralexamcommittee謝建興;陳右穎;盧郁仁;何明樺;張凱閔zh_TW
dc.contributor.oralexamcommitteeJiann-Shing Shieh;You-Yin Chen;Yu-Jen Lu;Ming-Hua Ho;Ke-Vin Changen
dc.subject.keyword超音波,內視鏡脊椎手術,椎間盤,微創手術,正中神經,臂神經叢,zh_TW
dc.subject.keywordultrasound,endoscopic spine surgery,intervertebral disc,minimally invasive surgery,median nerve,brachial plexus,en
dc.relation.page70-
dc.identifier.doi10.6342/NTU202300749-
dc.rights.note同意授權(限校園內公開)-
dc.date.accepted2023-05-02-
dc.contributor.author-college工學院-
dc.contributor.author-dept醫學工程學系-
顯示於系所單位:醫學工程學研究所

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