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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/84086完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 郭佳瑋(Chia-Wei Kuo) | |
| dc.contributor.author | Kuan-Yu Shih | en |
| dc.contributor.author | 施冠瑜 | zh_TW |
| dc.date.accessioned | 2023-03-19T22:04:37Z | - |
| dc.date.copyright | 2022-08-19 | |
| dc.date.issued | 2022 | |
| dc.date.submitted | 2022-07-19 | |
| dc.identifier.citation | 一、中文書籍 • 陳忠仁 (2022)。策略管理-競爭優勢與經營發展。初版。台北。華泰文化。 二、中文雜誌期刊與研究報告 • 鄧哲明 (2013)。新藥的研發流程概論。科學月刊https://pansci.asia/archives/38529 • 藍佳斐 (2018)。參加亞太經濟合作組織罕見疾病政策對話報告。衛生福利部國民健康署。https://report.nat.gov.tw/ReportFront/ReportDetail/detail?sysId=C10701370 • 勤業眾信Deloitte (2021)。生醫合作交易白皮書2021。https://www2.deloitte.com/content/dam/Deloitte/tw/Documents/life-sciences-health-care/rp211220-lshc-white-paper.pdf • 勤業眾信Deloitte (2019)。生技製藥合作交易白皮書-啟動AI藥物開發新時代 https://www2.deloitte.com/content/dam/Deloitte/tw/Documents/life-sciences-health-care/2019-LSHC-whitepaper.pdf • 勤業眾信Deloitte (2017)。新藥研發與併購整合白皮書2017。https://www2.deloitte.com/tw/tc/pages/life-sciences-and-healthcare/articles/2017integration-rd-ma.html • 勤業眾信Deloitte (2016)。新藥研發模式白皮書2016。https://www2.deloitte.com/tw/tc/pages/life-sciences-and-healthcare/articles/2016drug-development.html • 許毓真,蔡維原、鄭宇婷、王意婷、巫文玲、林建邦、張慧潔、陳思豪、劉曉君 (2021)。2021醫藥產業年鑑。財團法人生物技術開發中心。 • 資誠PWC(2019)。2019台灣生醫併購白皮書。https://www.pwc.tw/zh/publications/topic-invest/assets/2019-bio-mna.pdf • 劉玳縈(2020)。外部創新模式以製藥企業為例。科技政策研究與資訊中心。https://portal.stpi.narl.org.tw/index?p=article&id=4b1141427395c699017395c756b32010 三、中文新聞報紙與網路資源 • 國民健康署婦幼健康組。(2012)。什麼是罕見疾病?。衛生福利部國民健康署。 https://www.hpa.gov.tw/Pages/Detail.aspx?nodeid=805&pid=4298 • 張漢宜。(2011年4月)。新興市場獨特商機,第一世界也來搶食。天下雜誌。 https://www.cw.com.tw/article/5007818 • 袁勇。(2018年5月14日). 武田牽手夏爾將成就日企最大海外併購。中國經濟網。https://m.jrj.com.cn/madapter/finance/2018/05/14163624536568.shtml • 游舒帆。(2019年07月3日) 。 產品生命週期,如何延續? 以iPhone為例,企業這樣找衝刺新品的最佳時機。聊聊商業思維商業周刊。 https://www.businessweekly.com.tw/management/blog/26177 • GENEONLINE。(2017) 撥雲見日:從 2017日本生技展見證日本生醫產業的轉守為攻。GENEONLINE。https://geneonline.news/2017-biotech-japan-2017-report/ • MAU, A. (2022)。繼革命性CRISPR療法,Intellia的FDA認證孤兒藥再加一。 https://geneonline.news/intellia-tcelltherapy-aml/ • 工商時報/台北訊(2015)。韋伯攻4醫療領域重振聲威。工商時報。 https://trpma.org.tw/eng/news/news_1713 • 玉琴(2020年4月)。日本製藥業強大,但為何沒能誕生世界級的製藥公司?。鈦媒體。 https://read01.com/zh-tw/RMaQOM2.html#.Yo-kiO5Bw2x • 李吉仁(2019年4月)。驅動轉型成為轉機。哈佛商業評論。 • 財訊(2018年4月)。最大客戶日本政府緊縮預算,武田製藥展開海外購併。Wealth Magazine。https://www.wealth.com.tw/articles/359619f1-9ab7-4f09-a6db-f990c521add9 • 鉅亨網新聞中心(2014年8月)。對抗衰退提振經濟-全球貨幣政策的分歧與走向。鉅亨網新聞中心。 https://news.cnyes.com/news/id/1371466/print?exp=a • 新浪財經(2009年1月26日)。輝瑞最近十年內主要購併案。新浪財經。http://finance.sina.com.cn/stock/usstock/c/20090126/22445799105.shtml 四、英文期刊與雜誌 • Michael Hay, D. W. T., John L Craighead, Celia Economides & Jesse Rosenthal. (2014). Clinical development success rates for investigational drugs. nature biotechnology, 32, 40-51. • Porter, M. E. (1980). Competitive strategy : techniques for analyzing industries and competitors / Michael E. Porter. Free Press. 五、英文書籍 • Hill, C.W.L., Jones, G. R. (2001). Strategic Management: An Integrated Approach. Boston, MA: Houghton Mifflin Company. • Aguilar, F. (1967). Scanning the Business Environment. Macmillan. • Austin, J. E. (1990). Managing In Developing Countries. 六、英文新聞報紙與網路資源 • Takeda (2018). FY2017 DATABOOK • Takeda (2019). FY2018 DATABOOK • Henderson, B. (1970 ). The Product Portfolio. https://www.bcg.com/publications/1970/strategy-the-product-portfolio • Sagonowsky, E. (2020). The top 20 pharma companies by 2019 revenue. https://www.fiercepharma.com/special-report/top-20-pharma-companies-by-2019-revenue • STOYE, E. (2017). Takeda tightens focus on core areas with multiple deals. https://www.chemistryworld.com/news/takeda-tightens-focus-on-core-areas-with-multiple-deals/3007974.article • Rare Diseases at FDA. (2020). https://www.fda.gov/patients/rare-diseases-fda • BBC(2018). Takeda agrees to buy Shire in £46bn deal. https://www.bbc.com/news/business-44038049 七、英文學位論文與研究報告 • Yin, R. K. (1994). Discovering the Future of the Case Study. Method in Evaluation Research. Evaluation Practice, 15(3), 283–290. https://doi.org/10.1177/109821409401500309 • Eisenhardt, K. M. (1989). Building Theories from Case Study Research. The Academy of Management Review, 14(4), 532–550. https://doi.org/10.2307/258557 • IQVIA(2021). Global Medicine Spending and Usage Trends outlook to 2025 https://www.iqvia.com/insights/the-iqvia-institute/reports/global-medicine-spending-and-usage-trends-outlook-to-2025 • EvaluatePharma (2019). World preview 2019, Outlook to 2024 https://www.evaluate.com/thought-leadership/pharma/evaluatepharma-world-preview-2019-outlook-2024 • Evaluate Pharma (2019). Orphan Drug Report 2019 https://www.evaluate.com/sites/default/files/media/download-files/EvaluatePharma_Orphan_Drug_Report_2019.pdf • Deloitte (2015). Measuring the return from pharmaceutical innovation 2015 • PhRMA (2016). 2016 Profile Pharmaceutical Research Industry https://www.bms.com/assets/bms/us/en-us/pdf/biopharmaceutical-research-industry-2016-profile.pdf • IMS (2015). Global Medicines Use in 2020-Outlook and Implications. IMS Institute for Healthcare informatics https://www.iqvia.com/-/media/iqvia/pdfs/institute-reports/global-medicines-use-in-2020 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/84086 | - |
| dc.description.abstract | 隨著2000年後藥品研發成本不斷增加,國際藥廠漸漸減少內部創新比重,轉而透過收購取得核心治療領域之突破性研發技術,以保持研發保持領先的優勢。即便過去研究衡量購併交易失敗率高達五成以上,只有三成企業有達到綜效。 然而資誠2019年台灣生醫併購白皮書仍指出,生醫產業在2018年為全球併購金額最高之產業,總金額達3761億美元,其中以生技製藥的併購交易達2723億美元最為活絡。歐美製藥企業優先運用購併交易提升企業規模,達成快速成長已經成為常態。傳統日本製藥企業過去專注於提升自身研發實力,鮮少透過跨國大型併購交易達到成長的目標,然而在日本市場經濟政策環境變化造成市場萎縮,加上生醫科技發展趨勢非日本製藥過去著重研發的小分子藥物。造成日本製藥企業面臨內外夾擊的壓力,尋求外部資源進行轉型迫在眉睫。 本論文的研究方法採用個案研究方式,以日本製藥產業個案公司透過購併,分階段轉型過程進行分析。運用企業變革轉型成長架構(C-SOP)分析個案公司轉型變革要素。針對個案公司歷史脈絡進行次級資料收集並進行分析,探討個案公司面臨轉型歷程與轉型後產生的綜效與問題分析。身為日本傳統製藥企業在轉型進入全球化的過程中,首先由興業發展,家族企業轉為專業經理人進入組織啟動組織重塑,進行特定領域中小型藥品企業收購,逐步轉入特殊治療領域,進入歐美銷售市場渠道。第二改造階段,透過大規模跨國購併夏爾罕見藥品製藥商,加速全球市場滲透。研究結果發現,身為後進者選擇購併進入立基罕病領域市場,兼具穩定與效率。購併獲取進入成長階段的金牛藥品,同時獲得研發後期的罕見疾病藥物,取得未來成長動能。營收在購併後大幅度成長,主要來自歐美市場的營收挹注。個案公司轉型後晉升亞洲唯一全球10大製藥公司。 | zh_TW |
| dc.description.abstract | As the cost of drug research and development continued to increase after the year of 2000, international pharmaceutical companies gradually reduced the proportion of internal innovation, and instead acquired breakthrough research and development technologies in core therapeutic areas through acquisitions to maintain their leading edge in research and development. Although some studies have pointed out that the failure rate of mergers and acquisitions exceeds 50%, only 30% of enterprises have achieved synergy. PwC Taiwan published 2019 Taiwan Biomedical M&A report still pointed out that the biomedical industry was the industry with the highest M&A value in the world in 2018, with a total value of US$376.1 billion, of which pharmaceutical M&A transactions reached US$272.3 billion the most active. It has become normal for Western pharmaceutical companies to use M&A to increase their scale and achieve rapid growth. Traditional Japanese pharmaceutical companies used to focus on improving their R&D capabilities and rarely achieved growth goals through large-scale cross-border M&A transactions. However, changes in the Japanese economic policy and environment have caused the market to shrink, and the development trend of biomedical technology is not the small molecule drugs that Japanese pharmaceuticals used to focus on. As a result, Japanese pharmaceutical companies are facing internal and external pressure, and must seek external resources for transformation as soon as possible. The research method of this paper adopts the case study method. Analysis of Japanese pharmaceutical company undergoing various stages of transformation through M&A. Analyze the elements of the company's transformation and change with the Enterprise Transformation Growth Framework (C-SOP). Secondary data collection and analysis are carried out for the historical context of the case company. Discuss the transformation process faced by the case company and the synergy and problem analysis after the transformation. As a traditional Japanese pharmaceutical company in the process of transforming into globalization. First, the family business was transformed into a professional manager to enter the organization, and the organization remodeling was initiated. Focus on the acquisition of small and medium-sized pharmaceutical companies in specific fields, gradually transfer to special treatment fields, and enter Western market channels. In the second stage of transformation, through large-scale cross-border acquisitions of rare disease pharmaceutical company” Shire,” the global market penetration was accelerated. The results of the study found that, as a second mover, choosing to acquire and enter a niche market in the field of rare diseases can be both financial stable and efficient. Through acquisitions, cash cow drugs in the growth stage and rare disease drugs in the late stage of R&D can be obtained, so as to obtain future growth momentum. Revenue has grown significantly after the acquisition, mainly from European and American markets. After the transformation of the case company, it was promoted to the top 10 pharmaceutical companies in the world, the only one in Asia. | en |
| dc.description.provenance | Made available in DSpace on 2023-03-19T22:04:37Z (GMT). No. of bitstreams: 1 U0001-1307202200490800.pdf: 4793600 bytes, checksum: 02a0e9a91e61a344995351c5e616c560 (MD5) Previous issue date: 2022 | en |
| dc.description.tableofcontents | 目 錄 誌謝…………………………………………………………………………………………… i 中文摘要……………………………………………………………………………… ii 英文摘要…………………………………………………………………………………iii 目錄……………………………………………………………………………………………… v 圖目錄……………………………………………………………………………………… vii 表目錄…………………………………………………………………………………… ix 第一章 緒論 第一節 研究背景與動機……………………………………………………1 第二節 研究目的…………………………………………………………………3 第三節 研究方法與架構 ………………………………………………3 第二章 文獻探討 第一節 併購及效率理論 …………………………………………………6 第二節 產業分析理論與架構 ……………………………………… 9 第三節 BCG矩陣……………………………………………………………………15 第四節 C-SOP企業變革轉型成長架構 ……………………18 第三章 國際醫藥產業分析 第一節 產業發展趨勢分析…………………………………………………………19 第二節 產業競爭分析……………………………………………………………………26 第三節 產業競合趨勢分析…………………………………………………………39 第四章 個案公司轉型歷程 第一節 個案公司沿革………………………………………………………………………46 第二節 面臨危機與進入轉型 ………………………………………………………48 第三節 外部環境分析 …………………………………………………………………56 第四節 併購轉型綜效分析 ………………………………………………………64 第五章 結論與建議 第一節 研究結論……………………………………………………………………75 第二節 研究建議……………………………………………………………………77 第三節 研究限制……………………………………………………………………78 參考文獻 …………………………………………………………………………………80 | |
| dc.language.iso | zh-TW | |
| dc.subject | 購併 | zh_TW |
| dc.subject | 轉型 | zh_TW |
| dc.subject | 綜效 | zh_TW |
| dc.subject | 全球化 | zh_TW |
| dc.subject | 罕見疾病 | zh_TW |
| dc.subject | 日本藥品公司 | zh_TW |
| dc.subject | rare disease | en |
| dc.subject | Japanese pharmaceutical companies | en |
| dc.subject | M&A | en |
| dc.subject | transformation | en |
| dc.subject | synergies | en |
| dc.subject | globalization | en |
| dc.title | 後進藥廠之階段轉型與成長策略分析-以日商T公司為例 | zh_TW |
| dc.title | Analysis of the Stage Transformation and Growth Strategy of the Second-Mover Pharmaceutical Company- A Case Study of Japanese T company | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 110-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 胡凱焜(Kae-Kuen Hu) | |
| dc.contributor.oralexamcommittee | 余峻瑜(Jun-Yu Yu) | |
| dc.subject.keyword | 日本藥品公司,購併,轉型,綜效,全球化,罕見疾病, | zh_TW |
| dc.subject.keyword | Japanese pharmaceutical companies,M&A,transformation,synergies,globalization,rare disease, | en |
| dc.relation.page | 83 | |
| dc.identifier.doi | 10.6342/NTU202201438 | |
| dc.rights.note | 同意授權(限校園內公開) | |
| dc.date.accepted | 2022-07-20 | |
| dc.contributor.author-college | 進修推廣學院 | zh_TW |
| dc.contributor.author-dept | 生物科技管理碩士在職學位學程 | zh_TW |
| dc.date.embargo-lift | 2025-07-01 | - |
| 顯示於系所單位: | 生物科技管理碩士在職學位學程 | |
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