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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 陳為堅 | zh_TW |
dc.contributor.advisor | Wei J. Chen | en |
dc.contributor.author | 陳姿羽 | zh_TW |
dc.contributor.author | Tzu-Yu Chen | en |
dc.date.accessioned | 2023-03-01T17:06:48Z | - |
dc.date.available | 2023-11-10 | - |
dc.date.copyright | 2023-05-26 | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2023-01-06 | - |
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Validity of EQ-5D in general population of Taiwan: results of the 2009 National Health Interview and Drug Abuse Survey of Taiwan. Qual Life Res, 24(10), 2541-2548. https://doi.org/10.1007/s11136-015-0978-7 | - |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/83287 | - |
dc.description.abstract | 背景與目的
頻繁的飲酒行為與較差的健康相關生活品質存在著一定的關聯性,更有研究指出在此關係當中可能存有性別差異。由於女性的性別角色、飲酒規範的轉變,近年來工業化國家的飲酒盛行率之性別差異隨著時間逐漸縮小。然而,在過去飲酒盛行率相對較低的地區,尤其是亞洲國家,飲酒行為與生活品質之間的關係是否發生了變化仍較未知。因此,本研究的目的便是希望利用近年台灣的全國調查資料,檢視不同的飲酒行為與健康相關生活品質的關係,以及是否存在性別差異。 方法 本研究樣本為 2018 年全國物質使用調查中的 15,028 位 18-64 歲成年受訪者,所有受訪者皆完成了自我填答式問卷,內容包含了受訪者的基本社會人口學特徵、合法及非法的物質使用情形、生活品質以及憂鬱情形。本研究根據調查中的一系列飲酒相關問題,以及酒精使用疾患確認檢測 (Alcohol Use Disorder Identification Test, AUDIT) 之分數來進行不同飲酒行為的劃分。受試者被區分為:從未飲酒者、戒酒者、低風險飲酒者及有害飲酒者等四個組別。受試者之自陳健康相關生活品質則是利用 EuroQoL-5D (EQ-5D) 量表來進行量測。本研究使用受訪者報告受損生活品質 (impaired HRQoL) 的勝算比,以及 EQ-VAS 的平均分數,來評估各個飲酒行為在 EQ-5D 中不同面向以及整體生活品質的差異,並且同時檢視在相同飲酒行為間是否存在性別差異。另外也利用了多元羅吉斯迴歸分析檢定性別與飲酒行為之交互作用項,探討交互作用是否僅存在於 EQ-5D 的特定面向中。 結果 疼痛/不舒服以及焦慮/憂鬱為造成受訪者生活品質下降最常見的原因,約有15-25%的受訪者回報了其有相關問題,而無論目前是否具有飲酒習慣,具有飲酒經驗的受訪者與從未飲酒者相比,皆有較高的勝算會有疼痛/不舒服與焦慮/憂鬱的問題。就整體的生活品質而言,無論在男性還是女性當中,有害飲酒者的平均 EQ-VAS 分數 (男性平均 85.65 分;女性平均 82.73 分) 皆顯著低於從未飲酒者 (男性平均 88.59 分;女性平均 88.69 分) 和低風險飲酒者 (男性平均 88.62 分;女性平均 88.40 分)。檢定性別與飲酒行為的交互作用項,結果僅在焦慮/憂鬱的面向中發現,各個飲酒行為間存在著顯著不同的性別差異。隨著飲酒問題嚴重程度上升,差異也逐漸加大,以有害飲酒者組別的性別差異最為顯著,女性焦慮/憂鬱的盛行率約為男性的 2 倍。整體生活品質之性別差異則僅存在於有害飲酒者組別,女性的平均 EQ-VAS 分數顯著低於男性 2.92 分。 結論 目前不同飲酒行為與健康相關生活品質的關係顯示,相比於未飲酒者及低風險飲酒者,有害飲酒者的生活品質顯著較差,然而在其他組別間則皆無顯著差異。性別差異僅存在於有害飲酒者組別,其中,該組別男女的焦慮/憂鬱盛行率之差異也顯著高於其他飲酒行為者。 | zh_TW |
dc.description.abstract | Background and aim
More pervasive alcohol use behaviors have been associated with poorer health-related quality of life (HRQoL), and some studies suggested gender differences might exist in such relationship. Owing to changes in gender roles and drinking norms for women, gender differences in alcohol use prevalence in industrialized countries have been narrowing over time. However, it remains little known whether the relationship between alcohol use behaviors and HRQoL changed in regions that used to have relatively low prevalence of alcohol use, particularly Asian countries. Using the data from the most recent national survey in Taiwan, this study aims to (1) investigate the relationship between alcohol use behaviors and HRQoL; and (2) examine whether there are gender differences in these relationships. Methods Participants were 15,028 adults aged 18-64 years from the 2018 National Survey of Substance Use (NSSU). All respondents completed a self-interview questionnaire with information on their sociodemographic characteristics, legal and illegal substance use behaviors, HRQoL, and depression symptoms. Alcohol use behaviors were identified using a variety of alcohol-related questions and the Alcohol Use Disorders Identification Test (AUDIT) scores. Participants were divided into four groups, which were abstainers, former drinkers, low-risk drinkers, and harmful drinkers. The EuroQoL five dimensions questionnaire (EQ-5D) was used to access the participants’ health status. We calculated the odds ratio for impaired HRQoL and the means of EQ-VAS for evaluating the differences among four types of alcohol use behaviors in five dimensions of EQ-5D and overall HRQoL. Also, we investigated whether there are gender differences in similar drinking patterns. Furthermore, we examined interaction terms for alcohol use behaviors with gender in multivariable logistic regression models to detect whether the interaction effect only existed in specific dimensions of EQ-5D. Results Pain/discomfort and anxiety/depression were the most common reasons that resulted in the decreased HRQoL among participants, where around 15-25% of them reported a problem. Participants who have had alcohol use experiences, whether they were current drinkers, had higher odds to report pain/discomfort, and anxiety/depression, regardless of gender. In terms of overall HRQoL, the mean of EQ-VAS among harmful drinkers (85.65 in males and 82.73 in females) was significantly lower than that among abstainers (88.59 in males and 88.69 in females) and low-risk drinkers (88.62 in males and 88.40 in females). A significant interaction between alcohol use behaviors and gender was only found in the dimension of anxiety/depression, where the gender differences increased with the level of alcohol use problems. The prevalence of anxiety/depression among females was almost 2-fold compared to that of males. The gender difference in overall HRQoL was only found in the harmful drinkers' group, where the average EQ-VAS of females was 2.92 significantly below that of males. Conclusion There is no significant difference in HRQoL between abstainers and the other types of drinkers, except for harmful drinkers, where harmful drinkers reported a significantly lower HRQoL than abstainers and low-risk drinkers in both genders. The gender difference was only found in the group of harmful drinkers, where the difference in the prevalence of anxiety/depression between males and females was also the largest among the four groups of participants. | en |
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dc.description.tableofcontents | Table of contents
誌謝 i 中文摘要 ii Abstract iv Table of contents vi List of Tables vii List of Figures viii List of Supplemental Materials ix Chapter 1 Introduction 1 Chapter 2 Materials and Methods 4 2.1 Participants 4 2.2 Measures 4 2.3 Statistical analysis 6 Chapter 3 Results 8 3.1 Characteristics of Study Participants 8 3.2 Relationship between the impaired HRQoL and alcohol use behaviors 8 3.3 Association between Overall HRQoL and alcohol use behaviors 9 3.4 Interaction effect between gender and alcohol use behaviors 10 3.5 Sensitivity analysis 10 3.6 An alcohol-related problem among participants 11 Chapter 4 Discussion 12 4.1 Low-risk drinkers didn’t show better HRQoL than abstainers 12 4.2 Gender difference in the harmful drinkers 14 4.3 Limitations 16 4.4 Conclusion 17 Reference 18 Supplemental Materials 30 List of Tables Table 1a. Sociodemographic characteristics of male participants in the 2018 National Survey of Substance Use in Taiwan, by alcohol use behaviors 22 Table 1b. Sociodemographic characteristics of female participants in the 2018 National Survey of Substance Use in Taiwan, by alcohol use behaviors 23 Table 2. Distribution of EQ-5D-5L and CES-D profiles among participants in the 2018 National Survey of Substance Use in Taiwan according to alcohol use behaviors by gender 24 Table 3. The association between two domains of impaired health-related quality of life (HRQoL) and alcohol use behaviors and means of EQ-VAS among participants in the 2018 National Survey of Substance Use in Taiwan 25 Table 4. Multivariable logistic regression of two domains of impaired health-related quality of life (HRQoL) on alcohol use behaviors and gender interactions 26 List of Figures Figure 1. Gender ratios (female-to-male) of the prevalence of (a) pain/discomfort and (b) anxiety/depression in the EQ-5D-5L and (c) CES-D by alcohol use behaviors 28 Figure 2. Gender differences (female-to-male) of the EQ-VAS means by alcohol use behaviors 29 List of Supplemental Materials Table S1. The association between two domains of impaired health related quality of life (HRQoL) and alcohol use behaviors (categorized by AUDIT-C) among participants in the 2018 National Survey of Substance Use in Taiwan 30 Table S2. Prevalence of the experience of being mentally or physically harmed by someone who drank alcohol among participants in the 2018 National Survey of Substance Use in Taiwan 31 Figure S1. Prevalence of being diagnosed with one or more major physical diseases by alcohol use behaviors 32 Figure S2. Gender ratios (female-to-male) of the prevalence of (a) pain/discomfort and (b) anxiety/depression in the EQ-5D-5L in two classification approaches for alcohol use behaviors 33 Figure S3. Means of the EQ-VAS by gender in two classification approaches for alcohol use behaviors 34 | - |
dc.language.iso | en | - |
dc.title | 台灣民眾飲酒行為與健康相關生活品質之關係上的性別差異 | zh_TW |
dc.title | Gender Difference in the Relationship between Alcohol Use Behaviors and Health-related Quality of Life among the General Population in Taiwan | en |
dc.title.alternative | Gender Difference in the Relationship between Alcohol Use Behaviors and Health-related Quality of Life among the General Population in Taiwan | - |
dc.type | Thesis | - |
dc.date.schoolyear | 111-1 | - |
dc.description.degree | 碩士 | - |
dc.contributor.oralexamcommittee | 陳亮妤;張書森;郭柏秀 | zh_TW |
dc.contributor.oralexamcommittee | Lian-Yu Chen;Shu-Sen Chang;Po-Hsiu Kuo | en |
dc.subject.keyword | 酒精使用行為,健康相關生活品質,EQ-5D,性別差異, | zh_TW |
dc.subject.keyword | alcohol use behaviors,health-related quality of life,EQ-5D,gender difference, | en |
dc.relation.page | 34 | - |
dc.identifier.doi | 10.6342/NTU202300027 | - |
dc.rights.note | 未授權 | - |
dc.date.accepted | 2023-01-09 | - |
dc.contributor.author-college | 公共衛生學院 | - |
dc.contributor.author-dept | 流行病學與預防醫學研究所 | - |
顯示於系所單位: | 流行病學與預防醫學研究所 |
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