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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 呂東武(Tung-Wu Lu) | |
| dc.contributor.author | Hsuan-Yu Lu | en |
| dc.contributor.author | 呂軒瑜 | zh_TW |
| dc.date.accessioned | 2022-11-25T06:34:01Z | - |
| dc.date.copyright | 2022-01-03 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-12-21 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/82228 | - |
| dc.description.abstract | 精確量測人工置換膝關節之剛體運動與關節表面相對運動將有助於許多臨床醫療與研究。單髁人工膝關節相較於全膝人工關節其幾何較為對稱且體積較小，造成藉由醫學影像技術之量測精度不佳，其中以出平面位移與出平面旋轉影響尤具。然而，現存的關節運動量測方法不論在精度上或實驗驗證上皆有其限制。因此，本研究之目的在於：發展基於實體模型之2D/3D兩階段影像對位方法，以雙平面動態X光非侵入式測量功能性動作時，單髁人工膝關節之精確三維運動; 應用該方法以比較接受機器手臂輔助單髁膝關節置換與全膝人工關節置換，以評估人工關節設計對於退化性膝關節炎患者執行功能性動作時，所量測之膝關節運動學與表面運動學之影響; 結合統計形狀方法與雙平面影像重建個人化三維膝關節模型技術，並驗證此技術於重建接受單髁膝關節患者其膝關節模型之精度; 並進一步將藉由此重建模型以量測單髁膝關節運動學資訊。研究結果顯示實體模型之2D/3D兩階段影像對位方法量測單髁膝關節三維運動之精確度，均方根的平均值於膝關節角度誤差小於0.5°，膝關節移動誤差小於0.8 mm。以統計形狀模型重建模型搭配2D/3D兩階段影像對位方法量測單髁膝關節三維運動之精確度，均方根的平均值於膝關節角度誤差約在1.24-1.88°，膝關節移動誤差約在1.2-1.83 mm。本研究結果確認實體模型之2D/3D兩階段影像對位方法可精準量測單髁膝關節運動學資訊，此結論可有助於人體動作分析領域於三維動態X光之臨床應用，且搭配統計形狀模型方法將有助於減少人體輻射劑量。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-25T06:34:01Z (GMT). No. of bitstreams: 1 U0001-1812202100052400.pdf: 5597124 bytes, checksum: 9bee25eb98cf5fbf2fd0ec442d1a69d2 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | "中文摘要 ii Abstract iii Acknowledgements v Table of Contents vi List of Tables ix List of Figures Chapter 1. Introduction 1 1.1 Issue of Knee Osteoarthritis 1 1.2 Knee Kinematics Measurement Using Interleaved Bi-plane Fluoroscopy 4 1.3 Statistical Shape Modeling Method for 3D Knee Kinematics Measurement in UKA 8 1.4 Aims and Scope of the Dissertation 13 Chapter 2. Development and Accuracy Assessment of Model-Based 2D/3D Registration Methods for Uni-Compartmental Knee Kinematics with Bi-Plane Fluoroscopy 16 2.1 Novel Volumetric Model-Based 2D/3D Image Registration Method for Measuring Uni-compartmental Knee Kinematics 16 2.2.1. Overview 16 2.2.2. Computer Simulation 17 2.2.3. Determination of Gold Standard Knee Kinematics 18 2.2.4. Simulated Fluoroscopy Images from Gold Standard Kinematics 18 2.2.5. 3D/2D Image Registration Methods Using the AIMT Approach 19 2.2.6. Evaluation of Kinematics Accuracy 24 2.2.7. Statistical Analysis 24 2.3. Results 25 2.3.1. Computer Simulations 25 2.4. Discussion 28 2.4. Conclusions 31 Chapter 3. Comparisons of Rigid-Body and Surface Kinematics Between Robot-Assisted Uni-Compartmental and Total Knee Arthroplasty During Functional Activities 32 3.1 Comparisons of Rigid-Body and Surface Kinematics Between Robot-Assisted Uni-Compartmental and Total Knee Arthroplasty During Active Knee Extension 33 3.2. Materials Methods 34 3.2.1 Subjects 34 3.2.2 CT-Based Bone Model and CAD Implant Model 34 3.2.3 2D/3D Image Registration 35 3.2.4 Data Analysis 38 3.2.5 Statistical Method 40 3.3. Results of Between UKA and TKA During AKE 40 3.4. Discussion of Between UKA and TKA During AKE 47 3.5. Conclusions of Between UKA and TKA During AKE 51 3.6 Comparisons of Rigid-Body and Surface Kinematics Between Robot-Assisted Uni-Compartmental and Total Knee Arthroplasty During Sit-to-stand 52 3.7. Materials Methods 53 3.8. Results of Between UKA and TKA During STS 53 3.9. Discussion of Between UKA and TKA During STS 60 3.10. Conclusions Between UKA and TKA During STS 64 Chapter 4. Three-Dimensional Reconstruction of Personalized Knee Surface Model from Bi-Plane Fluoroscopy Images Using Statistical Shape Modeling: Applications to Older Healthy Adults and Those with Uni-Compartmental Replacements 65 4.2. Materials Methods 66 4.2.1 Statistical shape modeling of the knee 66 4.2.2 Reconstruction of personalized statistical shape model 69 4.2.3 Evaluation of the SSM 74 4.2.4 Statistical analysis 76 4.3. Results 77 3.1 Principal component analysis 77 3.2 In vivo study 77 4.4. Discussion 82 4.4. Conclusions 86 Chapter 5. Three-Dimensional Uni-Compartmental Knee Kinematics Measured by Alternating Interpolation-Based Model Tracking with Personalized Statistical Shape Models Using Clinical Interleaved Bi-Plane Fluoroscopy 87 5.2. Materials Methods 88 5.2.1 Subjects 88 5.2.1 Experimental Protocol 88 5.2.2 Statistical Shape Modeling of the Knee 89 5.2.3 Model-based registration for measuring bone kinematics in old healthy 90 5.2.4 Model-based registration with two-phase optimization approach for measuring bone kinematics in UKA 91 5.2.5 Evaluation of the AIMT technique with SSM-reconstructed bone model 93 5.2.6 Statistical analysis 94 5.3. Results 98 5.4. Discussion 106 5.4. Conclusions 111 Chapter 6. Conclusions and Suggestions 112 6.1. Conclusions 112 6.1.1 Development of a new approach to measure 3D knee kinematics of UKA 112 6.1.2 Measuring 3D Knee Kinematics of UKA During Functional Activities 113 6.1.3 Reconstruction Personalized Knee Model for UKA Using SSM Modeling This study reconstructed the personalized SSM-reconstructed knee model for patients with UKA and old healthy populations. Using a two-phase optimization approach to reconstruct the SSM-based personalized bone model was possible. The accuracy in the SSM-reconstructed bone model of UKA for femur and tibia were less than 1.4 mm. Utilization of a two-phase optimization approach enabled reconstructing 3D SSM-based personalized knee model reconstructions with acceptable accuracy from available alternating bi-plane fluoroscopy systems in clinical settings. Moreover, this approach will be useful for generating personalized knee models for clinical applications using clinical bi-plane fluoroscopy systems with reducing radiation exposure. 113 6.1.4 Accuracy of Uni-compartmental Knee Kinematics Measurement Using Personalized SSM-based Model 114 6.2. Suggestions for Further Studies 115 6.2.1 Approach of Uni-compartment 3D Knee Kinematics Measurement 115 6.2.2 Measurement of Uni-compartment 3D Knee Kinematics and Surface Kinematics 115 6.2.3 Personalized Knee Model Using SSM Modeling 116 6.2.4 Uni-compartment 3D Knee Kinematics Measurement Using SSM Modeling 116 Appendix: Publication 118 (A) Refereed Journal Articles 118 (B) Proceeding Articles and Conference Presentations 119 (C) Title Pages of Published Journal Papers 122 Bibliography 125 " | |
| dc.language.iso | en | |
| dc.subject | 統計形狀模型 | zh_TW |
| dc.subject | 單髁膝關節置換手術 | zh_TW |
| dc.subject | 膝關節 | zh_TW |
| dc.subject | 運動學 | zh_TW |
| dc.subject | 表面運動學 | zh_TW |
| dc.subject | 三維動態X光 | zh_TW |
| dc.subject | 二維至三維影像比對 | zh_TW |
| dc.subject | 3D fluoroscopy | en |
| dc.subject | statistical shape model | en |
| dc.subject | 2D/3D image registration | en |
| dc.subject | uni-compartmental knee arthroplasty | en |
| dc.subject | knee | en |
| dc.subject | kinematics | en |
| dc.subject | surface kinematics | en |
| dc.title | 雙平面動態X光量測膝關節運動所使用不同模型之2D/3D影像對位方法之開發與評估：機器手臂輔助單髁與全人工膝關節置換術之比較研究 | zh_TW |
| dc.title | Development and Assessment of 2D/3D Registration Methods with Different Model Types for Knee Kinematics Using Bi-Plane Fluoroscopy: A Comparative Study on Robot-Assisted Uni-Compartmental and Total Knee Arthroplasty | en |
| dc.date.schoolyear | 110-1 | |
| dc.description.degree | 博士 | |
| dc.contributor.author-orcid | 0000-0002-3414-8092 | |
| dc.contributor.coadvisor | 林正忠(Cheng-Chung Lin) | |
| dc.contributor.oralexamcommittee | 許弘昌(Hsin-Tsai Liu),陳文斌(Chih-Yang Tseng),陳祥和,王廷明 | |
| dc.subject.keyword | 單髁膝關節置換手術,膝關節,運動學,表面運動學,三維動態X光,二維至三維影像比對,統計形狀模型, | zh_TW |
| dc.subject.keyword | uni-compartmental knee arthroplasty,knee,kinematics,surface kinematics,3D fluoroscopy,2D/3D image registration,statistical shape model, | en |
| dc.relation.page | 136 | |
| dc.identifier.doi | 10.6342/NTU202104542 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2021-12-21 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 醫學工程學研究所 | zh_TW |
| dc.date.embargo-lift | 2026-12-22 | - |
| 顯示於系所單位： | 醫學工程學研究所 | |
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