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  1. NTU Theses and Dissertations Repository
  2. 醫學院
  3. 護理學系所
Please use this identifier to cite or link to this item: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/82072
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dc.contributor.advisor李芸湘(Yun-Hsiang Lee)
dc.contributor.authorZi-Xuan Gaoen
dc.contributor.author高子媗zh_TW
dc.date.accessioned2022-11-25T05:35:14Z-
dc.date.available2024-12-28
dc.date.copyright2021-12-30
dc.date.issued2021
dc.date.submitted2021-12-28
dc.identifier.citation方圓媛、洪佳黛、詹瑞君、李芸湘(2017)‧談癌症病人家屬照顧者心理衝擊與介入方案‧榮總護理,34(3),220-226。https://doi.org/10.6142/vghn.34.3.220 陳盈吟、陳崇裕(2019)‧癌症免疫治療新進展‧中西整合醫學雜誌,21(1),1-7。 黃寶珠(2007)‧腸胃道癌症手術病人主要照顧者的負荷及相關因素‧台北市:臺北醫學大學。 衛生福利部國民健康署(2020,6月16日).108年國人死因統計結果.https://www.mohw.gov.tw/cp-16-54482-1.html 蕭孟蘋(2017).胃癌術後病人的症狀、害怕癌症復發及照護需求之探討.台北市:國立台灣大學。 American Cancer Society (2020). Treatment Support Caregivers and Family. https://www.cancer.org/treatment/caregivers.html Akizuki, N., Yamawaki, S., Akechi, T., Nakano, T., Uchitomi, Y. (2005). Development of an Impact Thermometer for use in combination with the Distress Thermometer as a brief screening tool for adjustment disorders and/or major depression in cancer patients. Journal of Pain and Symptom Management, 29(1), 91-99. https://doi.org/10.1016/j.jpainsymman.2004.04.016 American Cancer Society (2014). What Causes Cancer? https://www.cancer.org/cancer/cancer-causes.html Ashrafian, S., Feizollahzadeh, H., Rahmani, A., Davoodi, A. (2018). The Unmet Needs of the Family Caregivers of Patients with Cancer Visiting a Referral Hospital in Iran. Asia-Pacific journal of Oncology Nursing, 5(3), 342-352. https://doi.org/10.4103/apjon.apjon_7_18 Australian Government Cancer Australia (2020). Cancer supportive care needs. https://www.edcan.org.au/edcan-learning-resources/supporting-resources/supportive-care/cancer-supportive-care-needs Afiyanti, Y., Gayatri, D., Besral, B., Haryani, H., Juliastuti, D. (2021). Unmet Supportive Care Needs Survey among Male Partners of Gynecological Cancer Survivors in Indonesia. Asia-Pacific journal of oncology nursing, 8(6), 662-669. https://doi.org/10.4103/apjon.apjon-2113 Buscemi, V., Font, A., Viladricht, C. (2010). Focus on relationship between the caregivers unmet needs and other caregiving outcomes in cancer palliative care. Psicooncologia, 7(1), 109-125. Balfe, M., O'Brien, K., Timmons, A., Butow, P., E, O. S., Gooberman-Hill, R., Sharp, L. (2016). The unmet supportive care needs of long-term head and neck cancer caregivers in the extended survivorship period. Journal of Clinical Nursing, 25(11-12), 1576-1586. https://doi.org/10.1111/jocn.13140 Berti, A., Bortolotti, R., Dipasquale, M., Kinspergher, S., Prokop, L., Grandi, G., Inchiostro, S., Paolazzi, G., Caffo, O., Veccia, A. (2021). Meta-analysis of immune-related adverse events in phase 3 clinical trials assessing immune checkpoint inhibitors for lung cancer. Critical Reviews in Oncology/Hematology, 162, 103351. https://doi.org/10.1016/j.critrevonc.2021.103351 Bonett, D. G., Wright, T. A. (2000). Sample size requirements for estimating pearson, kendall and spearman correlations. Psychometrika, 65(1), 23-28. https://doi.org/10.1007/BF02294183 Campione, J. R., Zebrak, K. A. (2020). Predictors of Unmet Need Among Informal Caregivers. The Journals of Gerontology: Series B. https://doi.org/10.1093/geronb/gbz165 Chen, S. C., Lai, Y. H., Liao, C. T., Huang, B. S., Lin, C. Y., Fan, K. H., Chang, J. T. (2014). Unmet supportive care needs and characteristics of family caregivers of patients with oral cancer after surgery. Psychooncology, 23(5), 569-77. https://doi.org/10.1002/pon.3458 Chen, S. C., Chiou, S. C., Yu, C. J., Lee, Y. H., Liao, W. Y., Hsieh, P. Y., Jhang, S. Y., Lai, Y. H. (2016) The unmet supportive care needs-what advanced lung cancer patients' caregivers need and related factors. Support Care Cancer, 24(7), 2999-3009. https://doi.org/10.1007/s00520-016-3096-3 de Souza, J. A., Yap, B. J., Hlubocky, F. J., Wroblewski, K., Ratain, M. J., Cella, D., Daugherty, C. K. (2014). The development of a financial toxicity patient-reported outcome in cancer: The COST measure. Cancer, 120(20), 3245-3253. https://doi.org/10.1002/cncr.28814 de Souza, J. A., Yap, B. J., Wroblewski, K., Blinder, V., Araújo, F. S., Hlubocky, F. J., Nicholas, L. H., O'Connor, J. M., Brockstein, B., Ratain, M. J., Daugherty, C. K., Cella, D. (2017). Measuring financial toxicity as a clinically relevant patient-reported outcome: The validation of the COmprehensive Score for financial Toxicity (COST). Cancer, 123(3), 476-484. https://doi.org/10.1002/cncr.30369 Fletcher, B. S., Miaskowski, C., Given, B., Schumacher, K. (2012). The cancer family caregiving experience: an updated and expanded conceptual model. European Journal of Oncology Nursing, 16(4), 387-398. https://doi.org/10.1016/j.ejon.2011.09.001 FACIT System. COST: a FACIT measure of financial toxicity. (2020). https :// wizard.facit .org/index .php?option=com facit view=searc h searc hPerf ormed =1 Fujinami, R., Sun, V., Zachariah, F., Uman, G., Grant, M., Ferrell, B. (2015). Family caregivers' distress levels related to quality of life, burden, and preparedness. Psycho-oncology, 24(1), 54-62. https://doi.org/10.1002/pon.3562 Girgis, A., Lambert, S., Johnson, C., Waller, A., Currow, D. (2013). Physical, psychosocial, relationship, and economic burden of caring for people with cancer: a review. Journal of oncology practice, 9(4), 197-202. https://doi.org/10.1200/JOP.2012.000690 Girgis, A., Lambert, S. D., McElduff, P., Bonevski, B., Lecathelinais, C., Boyes, A., Stacey, F. (2013). Some things change, some things stay the same: a longitudinal analysis of cancer caregivers' unmet supportive care needs. Psychooncology, 22(7), 1557-1564. https://doi.org/10.1002/pon.3166 Girgis, A., Lambert, S., Lecathelinais, C. (2011). The supportive care needs survey for partners and caregivers of cancer survivors: development and psychometric evaluation. Psychooncology, 20(4), 387-393. https://doi.org/10.1002/pon.1740 Girgis, A., Stojanovski, E., Boyes, A., King, M., Lecathelinais, C. (2012). The next generation of the supportive care needs survey: a brief screening tool for administration in the clinical oncology setting. Psychooncology, 21(8), 827-835. https://doi.org/10.1002/pon.1973 Given, C. W., Given, B., Stommel, M., Collins, C., King, S., Franklin, S. (1992). The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. The Research in Nursing Health, 15(4), 271-283. https://doi.org/10.1002/nur.4770150406 Haley, W. E. (2003). Family caregivers of elderly patients with cancer: understanding and minimizing the burden of care. The journal of Supportive Oncology, 1(4 Suppl 2), 25-29. Heckel, L., Fennell, K. M., Orellana, L., Boltong, A., Byrnes, M., Livingston, P. M. (2018). A telephone outcall program to support caregivers of people diagnosed with cancer: utility, changes in levels of distress, and unmet needs. Supportive Care in Cancer, 26(11), 3789-3799. https://doi.org/10.1007/s00520-018-4246-6 Heckel, L., Fennell, K. M., Reynolds, J., Osborne, R. H., Chirgwin, J., Botti, M., Ashley, D. M., Livingston, P. M. (2015). Unmet needs and depression among carers of people newly diagnosed with cancer. European Journal of Cancer, 51(14), 2049-2057. https://doi.org/10.1016/j.ejca.2015.06.129 Hegel, M. T., Collins, E. D., Kearing, S., Gillock, K. L., Moore, C. P., Ahles, T. A. (2008). Sensitivity and specificity of the Distress Thermometer for depression in newly diagnosed breast cancer patients. Psycho-Oncology, 17(6), 556-560. https://doi.org/10.1002/pon.1289 Hellmann, M. D., Ciuleanu, T. E., Pluzanski, A., Lee, J. S., Otterson, G. A., Audigier-Valette, C., Minenza, E., Linardou, H., Burgers, S., Salman, P., Borghaei, H., Ramalingam, S. S., Brahmer, J., Reck, M., O'Byrne, K. J., Geese, W. J., Green, G., Chang, H., Szustakowski, J., Bhagavatheeswaran, P., Healey, D., Fu, Y., Nathan, F., Paz-Ares, L. (2018, 5). Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden. The New England Journal of Medicine, 378(22), 2093-2104. https://doi.org/10.1056/NEJMoa1801946 Hu, C.C., You, K.L., Tsai, L.Y., Fang, Y.Y., Jhang, S.Y., Lou, P.J., Wang, C.P., Ko, J.Y., Lee, Y.H., Lai, Y.H. (2019). Validation of the Supportive Care Needs Survey Screening Tool Chinese Version for Patients With Head and Neck Cancer in Taiwan. Journal of Nursing Research, 27(6). https://doi.org/10.1097/JNR.0000000000000360 Johansen, S., Cvancarova, M., Ruland, C. (2018). The Effect of Cancer Patients' and Their Family Caregivers' Physical and Emotional Symptoms on Caregiver Burden. Cancer Nursing, 41(2), 91-99. https://doi.org/10.1097/ncc.0000000000000493 Katie Lee, S. Y., Knobf, M. T. (2015). Primary Breast Cancer Decision-making Among Chinese American Women: Satisfaction, Regret. Journal of Nursing Research, 64(5), 391-401. https://doi.org/10.1097/nnr.0000000000000116 Kent, E. E., Dionne-Odom, J. N. (2019). Population-Based Profile of Mental Health and Support Service Need Among Family Caregivers of Adults With Cancer. Journal of Oncology Practice, 15(2), e122-e131. https://doi.org/10.1200/jop.18.00522 Kim, Y., Carver, C. S. (2019). Unmet needs of family cancer caregivers predict quality of life in long-term cancer survivorship. Journal of Cancer Survivorship, 13(5), 749-758. https://doi.org/10.1007/s11764-019-00794-6 Kruizinga, R., Hartog, I. D., Scherer-Rath, M., Schilderman, H., Van Laarhoven, H. (2017). Modes of relating to contingency: An exploration of experiences in advanced cancer patients. Palliative Supportive Care, 15(4), 444-453. https://doi.org/10.1017/s1478951516000936 Kwekkeboom, K., Zhang, Y., Campbell, T., Coe, C. L., Costanzo, E., Serlin, R. C., Ward, S. (2018). Randomized controlled trial of a brief cognitive-behavioral strategies intervention for the pain, fatigue, and sleep disturbance symptom cluster in advanced cancer. Psychooncology, 27(12), 2761-2769. https://doi.org/10.1002/pon.4883 Lambert, S. D., Girgis, A. (2017). Unmet Supportive Care Needs Among Informal Caregivers of Patients with Cancer: Opportunities and Challenges in Informing the Development of Interventions. Asia-Pacific Journal of Oncology Nursing, 4(2), 136-139. https://doi.org/10.4103/2347-5625.204485 Lambert, S. D., Harrison, J. D., Smith, E., Bonevski, B., Carey, M., Lawsin, C., Paul, C., Girgis, A. (2012). The unmet needs of partners and caregivers of adults diagnosed with cancer: a systematic review. BMJ Supportive Palliative Care, 2(3), 224-230. https://doi.org/10.1136/bmjspcare-2012-000226 Larkin, J., Chiarion-Sileni, V., Gonzalez, R., Grob, J. J., Cowey, C. L., Lao, C. D., Schadendorf, D., Dummer, R., Smylie, M., Rutkowski, P., Ferrucci, P. F., Hill, A., Wagstaff, J., Carlino, M. S., Haanen, J. B., Maio, M., Marquez-Rodas, I., McArthur, G. A., Ascierto, P. A., Long, G. V., Callahan, M. K., Postow, M. A., Grossmann, K., Sznol, M., Dreno, B., Bastholt, L., Yang, A., Rollin, L. M., Horak, C., Hodi, F. S., Wolchok, J. D. (2015). Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. New England Journal of Medicine, 373(1), 23-34. https://doi.org/10.1056/NEJMoa1504030 Lenz, E. R., Pugh, L. C., Milligan, R. A., Gift, A., Suppe, F. (1997). The middle-range theory of unpleasant symptoms: an update. ANS Advances in Nursing Science, 19(3), 14-27. Levy, D., Dhillon, H. M., Lomax, A., Marthick, M., McNeil, C., Kao, S., Lacey, J. (2019). Certainty within uncertainty: a qualitative study of the experience of metastatic melanoma patients undergoing pembrolizumab immunotherapy. Supportive Care in Cancer, 27(5), 1845-1852. https://doi.org/10.1007/s00520-018-4443-3 Litzelman, K. (2019). Caregiver Well-being and the Quality of Cancer Care. Seminars in Oncology Nursing, 35(4), 348-353. https://doi.org/10.1016/j.soncn.2019.06.006 Lynch, T. J., Bondarenko, I., Luft, A., Serwatowski, P., Barlesi, F., Chacko, R., Sebastian, M., Neal, J., Lu, H., Cuillerot, J. M., Reck, M. (2012). Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. Journal of Clinical Oncology, 30(17), 2046-2054. https://doi.org/10.1200/jco.2011.38.4032 Longacre M. L. (2013). Cancer caregivers information needs and resource preferences. Journal of cancer education : the official journal of the American Association for Cancer Education, 28(2), 297–305. https://doi.org/10.1007/s13187-013-0472-2 McFarland, D. C. (2019). New lung cancer treatments (immunotherapy and targeted therapies) and their associations with depression and other psychological side effects as compared to chemotherapy. General Hospital Psychiatry, 60, 148-155. https://doi.org/10.1016/j.genhosppsych.2019.04.001 Michot, J. M., Bigenwald, C., Champiat, S., Collins, M., Carbonnel, F., Postel-Vinay, S., Berdelou, A., Varga, A., Bahleda, R., Hollebecque, A., Massard, C., Fuerea, A., Ribrag, V., Gazzah, A., Armand, J. P., Amellal, N., Angevin, E., Noel, N., Boutros, C., Mateus, C., Robert, C., Soria, J. C., Marabelle, A., Lambotte, O. (2016). Immune-related adverse events with immune checkpoint blockade: a comprehensive review. European Journal of Cancer, 54, 139-148. https://doi.org/https://doi.org/10.1016/j.ejca.2015.11.016 Nesline, M. K., Knight, T., Colman, S., Patel, K. (2020). Economic Burden of Checkpoint Inhibitor Immunotherapy for the Treatment of Non–Small Cell Lung Cancer in US Clinical Practice. Clinical Therapeutics, 42(9), 1682-1698.e1687. https://doi.org/https://doi.org/10.1016/j.clinthera.2020.06.018 Niedzwiedz, C. L., Knifton, L., Robb, K. A., Katikireddi, S. V., Smith, D. J. (2019). Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority. BMC Cancer, 19(1), 943. https://doi.org/10.1186/s12885-019-6181-4 Nijboer, C., Triemstra, M., Tempelaar, R., Sanderman, R., van den Bos, G. A. (1999). Measuring both negative and positive reactions to giving care to cancer patients: psychometric qualities of the Caregiver Reaction Assessment (CRA). Social Science Medicine, 48(9), 1259-1269. https://doi.org/10.1016/s0277-9536(98)00426-2 Northouse, L. L. (1995). The impact of cancer in women on the family. Cancer Practice, 3(3), 134-142. Northouse, L. L., Katapodi, M. C., Song, L., Zhang, L., Mood, D. W. (2010). Interventions with family caregivers of cancer patients: meta-analysis of randomized trials. A Cancer Journal for Clinicians, 60(5), 317-339. https://doi.org/10.3322/caac.20081 Niu, A., Guo, C., Zhong, D., He, G., Zhong, W., Wang, L., Chen, Y., Shang, L., Fu, J. (2021). Identifying the Unmet Supportive Care Needs, with Concomitant Influencing Factors, in Family Caregivers of Cancer Patients in China. Asia-Pacific journal of oncology nursing, 8(3), 276-286. https://doi.org/10.4103/apjon.apjon_52_20 Nayak, L., Molinaro, A. M., Peters, K., Clarke, J. L., Jordan, J. T., de Groot, J., Nghiemphu, L., Kaley, T., Colman, H., McCluskey, C., Gaffey, S., Smith, T. R., Cote, D. J., Severgnini, M., Yearley, J. H., Zhao, Q., Blumenschein, W. M., Duda, D. G., Muzikansky, A., Jain, R. K., Wen, P. Y., Reardon, D. A. (2021). Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma. Journal of Experimental Clinical Cancer Research, 27(4), 1048-1057. https://doi.org/10.1158/1078-0432.Ccr-20-2500 Oechsle, K., Ullrich, A., Marx, G., Benze, G., Heine, J., Dickel, L.-M., Zhang, Y., Wowretzko, F., Wendt, K. N., Nauck, F., Bokemeyer, C., Bergelt, C. (2019). Psychological burden in family caregivers of patients with advanced cancer at initiation of specialist inpatient palliative care. BMC Palliative Care, 18(1), 102. https://doi.org/10.1186/s12904-019-0469-7 Postow, M. A., Sidlow, R., Hellmann, M. D. (2018). Immune-Related Adverse Events Associated with Immune Checkpoint Blockade. New England Journal of Medicine, 378(2), 158-168. https://doi.org/10.1056/NEJMra1703481 Postow, M. A., Sidlow, R., Hellmann, M. D. (2018). Immune-Related Adverse Events Associated with Immune Checkpoint Blockade. New England Journal of Medicine, 378(2), 158-168. https://doi.org/10.1056/NEJMra1703481 Palos, G. R., Mendoza, T. R., Liao, K. P., Anderson, K. O., Garcia-Gonzalez, A., Hahn, K., Nazario, A., Ramondetta, L. M., Valero, V., Lynch, G. R., Jibaja-Weiss, M. L., Cleeland, C. S. (2011). Caregiver symptom burden: the risk of caring for an underserved patient with advanced cancer. Cancer, 117(5), 1070-1079. https://doi.org/10.1002/cncr.25695 Reck, M., Mok, T. S. K., Nishio, M., Jotte, R. M., Cappuzzo, F., Orlandi, F., Stroyakovskiy, D., Nogami, N., Rodríguez-Abreu, D., Moro-Sibilot, D., Thomas, C. A., Barlesi, F., Finley, G., Lee, A., Coleman, S., Deng, Y., Kowanetz, M., Shankar, G., Lin, W., Socinski, M. A. (2019). Atezolizumab plus bevacizumab and chemotherapy in non-small-cell lung cancer (IMpower150): key subgroup analyses of patients with EGFR mutations or baseline liver metastases in a randomised, open-label phase 3 trial. The Lancet Respiratory Medicine, 7(5), 387-401. https://doi.org/10.1016/s2213-2600(19)30084-0 Reck, M., Rodríguez-Abreu, D., Robinson, A. G., Hui, R., Csőszi, T., Fülöp, A., Gottfried, M., Peled, N., Tafreshi, A., Cuffe, S., O'Brien, M., Rao, S., Hotta, K., Leiby, M. A., Lubiniecki, G. M., Shentu, Y., Rangwala, R., Brahmer, J. R. (2016). Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer. The New England Journal of Medicine, 375(19), 1823-1833. https://doi.org/10.1056/NEJMoa1606774 Rini, B. I., Plimack, E. R., Stus, V., Gafanov, R., Hawkins, R., Nosov, D., Pouliot, F., Alekseev, B., Soulières, D., Melichar, B., Vynnychenko, I., Kryzhanivska, A., Bondarenko, I., Azevedo, S. J., Borchiellini, D., Szczylik, C., Markus, M., McDermott, R. S., Bedke, J., Tartas, S., Chang, Y. H., Tamada, S., Shou, Q., Perini, R. F., Chen, M., Atkins, M. B., Powles, T. (2019). Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma. The New England Journal of Medicine, 380(12), 1116-1127. https://doi.org/10.1056/NEJMoa1816714 Schmid-Büchi, S., Halfens, R. J. G., Müller, M., Dassen, T., van den Borne, B. (2013). Factors associated with supportive care needs of patients under treatment for breast cancer. European Journal of Oncology Nursing, 17(1), 22-29. https://doi.org/10.1016/j.ejon.2012.02.003 Schoenfeld, C., Libert, Y., Sattel, H., Canivet, D., Delevallez, F., Dinkel, A., Berberat, P. O., Wuensch, A., Razavi, D. (2018). Decisional conflict of physicians during the decision-making process for a simulated advanced-stage cancer patient: an international longitudinal study with German and Belgian physicians. BMC Cancer, 18(1), 1161. https://doi.org/10.1186/s12885-018-5071-5 Schulz, R., Beach, S. R. (1999). Caregiving as a Risk Factor for Mortality The Caregiver Health Effects Study. Journal of the American Medical Association, 282(23), 2215-2219. https://doi.org/10.1001/jama.282.23.2215 Sklenarova, H., Krümpelmann, A., Haun, M. W., Friederich, H. C., Huber, J., Thomas, M., Winkler, E. C., Herzog, W., Hartmann, M. (2015). When do we need to care about the caregiver? Supportive care needs, anxiety, and depression among informal caregivers of patients with cancer and cancer survivors. Cancer, 121(9), 1513-1519. https://doi.org/10.1002/cncr.29223 Teixeira, R. J., Applebaum, A. J., Bhatia, S., Brandão, T. (2018). The impact of coping strategies of cancer caregivers on psychophysiological outcomes: an integrative review. Psychology Research and Behavior Management, 11, 207-215. https://doi.org/10.2147/PRBM.S164946 Thorne, S. E., Oliffe, J. L., Oglov, V., Gelmon, K. (2013). Communication Challenges for Chronic Metastatic Cancer in an Era of Novel Therapeutics. Qualitative Health Research, 23(7), 863-875. https://doi.org/10.1177/1049732313483926 Thorne, S. E., Oliffe, J. L., Oglov, V., Gelmon, K. (2013). Communication challenges for chronic metastatic cancer in an era of novel therapeutics. Qualitative Health Research, 23 (7), 863-875. https://doi.org/10.1177/1049732313483926 Tran, G., Zafar, S. Y. (2018). Financial toxicity and implications for cancer care in the era of molecular and immune therapies. Annals of Translational Medicine, 6(9), 166-166. https://doi.org/10.21037/atm.2018.03.28 Trinh, S., Le, A., Gowani, S., La-Beck, N. M. (2019). Management of Immune-Related Adverse Events Associated with Immune Checkpoint Inhibitor Therapy: a Minireview of Current Clinical Guidelines. Asia-Pacific Journal of Oncology Nursing, 6(2), 154-160. https://doi.org/10.4103/apjon.apjon_3_19 Ullrich, A., Marx, G., Bergelt, C., Benze, G., Zhang, Y., Wowretzko, F., Heine, J., Dickel, L.-M., Nauck, F., Bokemeyer, C., Oechsle, K. (2020). Supportive care needs and service use during palliative care in family caregivers of patients with advanced cancer: a prospective longitudinal study. Supportive Care in Cancer. https://doi.org/10.1007/s00520-020-05565-z Vaddepally, R. K., Kharel, P., Pandey, R., Garje, R., Chandra, A. B. (2020). Review of Indications of FDA-Approved Immune Checkpoint Inhibitors per NCCN Guidelines with the Level of Evidence. Cancers, 12(3), 738. https://doi.org/10.3390/cancers12030738 Villadolid, J., Amin, A. (2015). Immune checkpoint inhibitors in clinical practice: update on management of immune-related toxicities. Translational Lung Cancer Research, 4(5), 560-575. https://doi.org/10.3978/j.issn.2218-6751.2015.06.06 Walker, M. S., Pohl, G. M., Houts, A. C., Peltz, G., Miller, P. J. E., Schwartzberg, L. S., Stepanski, E. J., Marciniak, M. (2017). Analysis of the psychological impact of cancer-related symptoms on patients with non-small cell lung cancer. Psychooncology, 26(6), 755-762. https://doi.org/10.1002/pon.4071 Wang, G. L., Hsu, S. H., Feng, A. C., Chiu, C. Y., Shen, J. F., Lin, Y. J., Cheng, C. C. (2011). The HADS and the DT for screening psychosocial distress of cancer patients in Taiwan. Psychooncology, 20(6), 639-646. https://doi.org/10.1002/pon.1952 Wang, T., Molassiotis, A., Chung, B. P. M., Tan, J. Y. (2018). Unmet care needs of advanced cancer patients and their informal caregivers: a systematic review. BMC Palliative Care, 17(1), 96. https://doi.org/10.1186/s12904-018-0346-9 Wang, T., Molassiotis, A., Tan, J.Y., Chung, B. P. M., Huang, H.Q. (2020). Prevalence and correlates of unmet palliative care needs in dyads of Chinese patients with advanced cancer and their informal caregivers: a cross-sectional survey. Supportive Care in Cancer. https://doi.org/10.1007/s00520-020-05657-w Weber, J. S., Hodi, F. S., Wolchok, J. D., Topalian, S. L., Schadendorf, D., Larkin, J., Sznol, M., Long, G. V., Li, H., Waxman, I. M., Jiang, J., Robert, C. (2017). Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced Melanoma. Journal of Clinical Oncology, 35(7), 785-792. https://doi.org/10.1200/jco.2015.66.1389 Zhang, B., Wu, Q., Zhou, Y. L., Guo, X., Ge, J., Fu, J. (2018). Immune-related adverse events from combination immunotherapy in cancer patients: A comprehensive meta-analysis of randomized controlled trials. International Immunopharmacology, 63, 292-298. https://doi.org/10.1016/j.intimp.2018.08.014
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/82072-
dc.description.abstract隨著科技醫療的進步,現今的癌症治療已進入新興免疫療法階段,促使愈來愈多癌症病人接受免疫治療,有著持續存活的機會,也表示有更多的家屬照顧者需要提供更長時間的照護工作,更突顯家屬照顧者的重要。反觀臨床上,病人及其家屬照顧者對免疫治療的療效、副作用的不確定性外,還有著諸多的心理壓力問題,但家屬照顧者不滿足的支持性照顧需求相關的研究卻十分有限,故本研究將針對癌症病人接受免疫治療期間之家屬照顧者支持性照護需求進行探討。 本研究採橫斷式描述性和相關性研究設計,經倫理委員會審查通過後,以立意取樣方式於北部某醫學中心腫瘤科病房收案,運用結構式問卷收集共70位成對之病患及家屬照顧者,研究工具包含:病人人口學特性與疾病特徵資料表(含財務安適度評估COST-FACIT)、免疫治療相關嚴重度評估分級表(CTCAE 5.0)、症狀困擾量表(SSS)、情緒溫度計量表(DT);家屬照顧者人口學特性與照顧相關特性資料表、症狀困擾量表、情緒溫度計量表、照顧者反應評估量表(CRA)、支持性照護需求量表(SCNS-P C),以描述性及推論性統計進行分析。 研究結果顯示:(1)免疫治療相關不良事件常見為皮膚乾燥、搔癢、丘疹;(2)病患及家屬照顧者症狀困擾前三名皆為疲倦、睡眠問題及疼痛;(3)病患及家屬照顧者情緒困擾分數平均各為3.6分與3.8分,大於等於4分以上,建議需要進一步轉介的比例各為47%及44%;(4)治療期間家屬照顧者之整體照顧負荷平均2.6分;(5)照顧者支持性照護需求前三項依序為訊息需求51.2分、免疫治療照護需求50.9分、健康照護服務需求41.9分;(6)病患症狀困擾、情緒困擾以及家屬照顧者的職業、經濟狀態、症狀困擾、情緒困擾、與整體照顧負荷程度皆與照顧者本身之支持性照護需求有顯著相關。 本研究結果發現接受免疫治療病患症狀如口腔炎,家屬照顧者症狀如疲倦、睡眠困擾的處理,以及情緒支持都是滿足家屬照顧者各層面支持性照顧需求的重要相關因素,顯見醫護人員對於情緒評估的重要性,此外;家屬照顧者的經濟狀態與照顧負荷程度也是重要相關因素,必要時,可以與醫療團隊討論並進行適當轉介;在家屬照顧者的免疫治療照護需求層面,建議未來能設置完善的後續居家照護諮詢管道,以滿足家屬照顧者的支持性照護需求。zh_TW
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dc.description.tableofcontents口試委員審定書......i 致 謝......ii 摘 要......iii Abstract......v 第一章 緒論......1 第一節 研究背景與重要性......1 第二節 研究問題與研究目的......4 第二章 文獻查證......5 第一節 癌症與免疫療法......5 第二節 癌症病人及其家屬照顧者之身心衝擊......9 第三節 家屬照顧者之支持性照護需求及其相關因素......12 第三章 研究方法......17 第一節 研究架構......17 第二節 研究設計......18 第三節 研究場所與對象......19 第四節 研究假設......21 第五節 名詞界定與操作型定義......22 第六節 研究工具......24 第七節 資料收集過程......28 第八節 資料處理與分析......29 第九節 研究倫理考量......31 第四章 研究結果......32 第一節 病患及家屬照顧者之人口學特性、疾病治療特質、財務安適度現況與家屬照顧相關特性......32 第二節 免疫治療相關不良事件嚴重度及發生率......39 第三節 症狀嚴重度、情緒困擾程度、照顧負荷程度及照護需求現況......43 第四節 人口學特性、疾病特徵、免疫不良事件嚴重度、照顧相關特性及經濟狀態之家屬照護需求差異......57 第五節 人口學特性、症狀及情緒困擾程度、財務安適度及照顧負荷程度與家屬照護需求之相關性......63 第五章 討論......66 第一節 免疫治療相關不良事件發生率與嚴重度、症狀困擾、情緒困擾與照顧負荷程度之現況探討......66 第二節 免疫治療期間家屬照顧者支持性照護需求之現況探討......69 第三節 免疫治療期間病患及家屬照顧者之人口學特性、症狀嚴重度、情緒困擾、照顧負荷程度及照護需求之相關性探討......71 第六章 結論......73 第一節 結論與建議......73 第二節 限制......75 參考資料......76 附錄一 自擬問卷之專家名單......88 附錄二 倫理委員會審查通過函......89 圖目錄 圖 1、研究架構圖......17 圖 2、資料收集流程圖......28 表目錄 表1、研究目的與統計分析方法......30 表 2、個案基本屬性(N=70)......33 表 3、疾病治療特質(N= 70)......35 表 4、病人財務安適度現況及分佈(N=70)......36 表 5、家屬照顧者基本屬性(N= 70)......38 表 6、免疫治療相關不良事件發生率及嚴重程度(N= 70)......41 表 7、不同治療組合間之免疫治療相關不良事件嚴重程度與分佈(N= 70)......42 表 8、病人身體症狀嚴重程度平均值及分佈(N= 70)......44 表 9、病人情緒困擾程度平均值及分佈(N= 70)......45 表 10、家屬照顧者身體症狀嚴重程度平均值及分佈(N= 70)......47 表 11、家屬照顧者情緒困擾程度平均值及分佈(N= 70)......48 表 12、家屬照顧者照顧負荷程度平均值排序及分佈(N= 70)......51 表 13、家屬照顧者照顧負荷程度單題平均值排序及分佈(N= 70)......52 表 14、家屬照顧者支持性照護需求平均值排序及分佈(N= 70)......53 表 15、家屬照顧者支持性照護需求單題平均值排序及分佈(N= 70)......54 表 16、家屬照顧者照護需求與病人及家屬本身之人口學特性差異(N= 70)......58 表 17、家屬照顧者照護需求與病人疾病特徵差異(N= 70)......59 表 18、家屬照顧者照護需求與免疫治療相關不良事件嚴重度差異(N= 70)......60 表 19、家屬照顧者照護需求與照顧相關特性差異(N= 70)......61 表 20、家屬照顧者照護需求與病人及家屬本身經濟狀態差異(N= 70)......62 表 21、家屬照顧者照護需求與病患及照顧者本身之年齡、教育程度、情緒困擾、症狀困擾與照顧負荷程度之相關性分析(N= 70)......65
dc.language.isozh-TW
dc.subject支持性照護需求zh_TW
dc.subject癌症zh_TW
dc.subject免疫療法zh_TW
dc.subject家屬照顧者zh_TW
dc.subjectSupportive Care Needsen
dc.subjectImmunotherapyen
dc.subjectFamily Caregiveren
dc.subjectCanceren
dc.title家屬照顧者於癌症病人接受免疫治療期間之支持性照護需求及其相關因素探討zh_TW
dc.titleRelated Factors and Supportive Care Needs in Family Caregivers with Cancer Patients undergoing Immunotherapyen
dc.date.schoolyear110-1
dc.description.degree碩士
dc.contributor.oralexamcommittee洪佳黛(Hsin-Tsai Liu),梁逸歆(Chih-Yang Tseng)
dc.subject.keyword癌症,免疫療法,家屬照顧者,支持性照護需求,zh_TW
dc.subject.keywordCancer,Immunotherapy,Family Caregiver,Supportive Care Needs,en
dc.relation.page89
dc.identifier.doi10.6342/NTU202104540
dc.rights.note同意授權(限校園內公開)
dc.date.accepted2021-12-28
dc.contributor.author-college醫學院zh_TW
dc.contributor.author-dept護理學研究所zh_TW
dc.date.embargo-lift2024-12-28-
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