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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 蕭旭峰(Shiuh-Feng Shiao) | |
| dc.contributor.author | Wan-Hsuan Li | en |
| dc.contributor.author | 李婉萱 | zh_TW |
| dc.date.accessioned | 2022-11-25T03:05:02Z | - |
| dc.date.available | 2026-07-12 | |
| dc.date.copyright | 2021-08-18 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-07-12 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/81850 | - |
| dc.description.abstract | 近年傷口研究主要趨勢聚焦於監控和介入因免疫系統不全，而難以癒合的傷口。對於這類傷口，醫院通常會以抗生素協助患者，但近年因抗藥性提升，導致其對慢性外傷的治療效果漸不理想。因此，以麗蠅為材料的蛆療法，成為治療慢性傷口選擇之一。蛆療法將麗蠅幼蟲以腐肉為生的特性應用於治療外傷，原先被視為另類醫療手段，現今則逐漸被重視。本研究之目的為藉由組織病理學角度評估台灣常見種類，大頭金蠅（Chrysomya megacephala）幼蟲在不同齡期作為蛆療法材料的可能性。以燙傷造成試驗用鼠體表外傷3天後，分為4組：實施蛆療法24小時、48小時、72小時的實驗組，以及不處理傷口的對照組。再經過治療後，表皮組織將被取下並做成組織切片。結果顯示，有經過蛆療法的傷口，前期恢復和對照組相同，12天後卻恢復得比對照組快速、完整，代表蛆療法非即時促進傷口癒合，大頭金蠅幼蟲確實有作為蛆療法材料的潛力。將蛆放置於傷口內24小時和72小時，傷口恢復前期速度較放置於傷口內48小時快速；將蛆放置於傷口內24小時和48小時，傷口恢復後期速度較放置於傷口內72小時快速。此外，大頭金蠅幼蟲可以在傷口內成長，但成長速度不一致，且待在傷口時間的時間越長，存活率越低。大頭金蠅確實對於燙傷癒合有正面影響，若要在台灣的醫療系統推行本土物種蛆療法，這是一個可行性很高的物種。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-25T03:05:02Z (GMT). No. of bitstreams: 1 U0001-0907202115453100.pdf: 66242285 bytes, checksum: 4aa747d3ccbf9ffd1af01d1f070a9386 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 口試委員審定書 i 中文摘要 ii 英文摘要 iii 目錄 iv 表目錄 vii 圖目錄 viii 壹、 前言 1 一、 蛆療法 1 （一）歷史 1 （二）機制 4 （三）應用 6 二、 蠅蛆症(myiasis)之於蛆療法 7 （一）蠅蛆症 7 （二）醫療蛆之選擇 8 三、 絲光綠蠅生物學以及分佈地區 9 四、 大頭金蠅之生物學以及分佈地區 10 五、 燒燙傷及蛆療法治療 11 六、 研究目的 13 貳、 材料方法 15 一、 試驗用蟲大頭金蠅 (Chrysomya megacephala) 15 （一） 大頭蠅 (Chrysomya megacephala) 之飼養 15 （二） 卵消毒 15 二、 試驗對象大鼠 16 （一） 及大鼠之傷口 16 （二） 植入幼蟲於傷口中 17 （三） 將幼蟲取出傷口 18 三、大頭金蠅幼蟲以及創傷組織之採樣及分析 18 （一） 大頭金蠅幼蟲之採樣及分析 18 （二） 創傷組織之採樣及分析 18 四、統計分析 21 參、 結果 22 一、 大頭金蠅幼蟲之分析結果 22 （一）幼蟲在傷口內的時間對幼蟲存活數之影響 22 （二）幼蟲在傷口內的時間對幼蟲齡期之影響 22 二、 大鼠創傷之分析結果 23 （一） 對照組 23 （二） 經歷24小時蛆療法之實驗組 23 （三） 經歷48小時蛆療法之實驗組 24 （四） 經歷72小時蛆療法之實驗組 24 肆、 討論 26 一、 大頭金蠅幼蟲 26 二、 大鼠傷口復原 27 （一） 經歷24小時蛆療法之實驗組 27 （二） 經歷48小時蛆療法之實驗組 28 （三） 經歷72小時蛆療法之實驗組 28 （四） 試驗綜合論述 30 三、實驗檢討 32 伍、 結論 33 陸、 參考文獻 34 | |
| dc.language.iso | zh-TW | |
| dc.subject | 蛆療法 | zh_TW |
| dc.subject | 大頭金蠅 | zh_TW |
| dc.subject | 麗蠅科 | zh_TW |
| dc.subject | Chrysomya megacephala | en |
| dc.subject | Calliphoridae | en |
| dc.subject | larval therapy | en |
| dc.title | 大頭金蠅（雙翅目：麗蠅科）對大鼠活體外傷之療效評估 | zh_TW |
| dc.title | Evaluation of therapeutic effects to the wound of rats by Chrysomya megacephala (Diptera: Calliphoridae) larvae | en |
| dc.date.schoolyear | 109-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 黃威翔(Wei-hsiang Huang) | |
| dc.contributor.oralexamcommittee | 杜武俊(Hsin-Tsai Liu),黃文伯(Chih-Yang Tseng) | |
| dc.subject.keyword | 大頭金蠅,蛆療法,麗蠅科, | zh_TW |
| dc.subject.keyword | Chrysomya megacephala,Calliphoridae,larval therapy, | en |
| dc.relation.page | 104 | |
| dc.identifier.doi | 10.6342/NTU202101367 | |
| dc.rights.note | 同意授權(全球公開) | |
| dc.date.accepted | 2021-07-13 | |
| dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
| dc.contributor.author-dept | 昆蟲學研究所 | zh_TW |
| dc.date.embargo-lift | 2026-07-12 | - |
| 顯示於系所單位： | 昆蟲學系 | |
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|---|---|---|---|
| U0001-0907202115453100.pdf 此日期後於網路公開 2026-07-12 | 64.69 MB | Adobe PDF |
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