請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80480完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 張博鈞(Po-Chun Chang) | |
| dc.contributor.author | Hsiang-Ling Huang | en |
| dc.contributor.author | 黃湘翎 | zh_TW |
| dc.date.accessioned | 2022-11-24T03:07:31Z | - |
| dc.date.available | 2021-12-30 | |
| dc.date.available | 2022-11-24T03:07:31Z | - |
| dc.date.copyright | 2021-12-30 | |
| dc.date.issued | 2021 | |
| dc.date.submitted | 2021-11-16 | |
| dc.identifier.citation | Al-Shammari, K. F., C. E. Kazor, and H. L. Wang. 2001. 'Molar root anatomy and management of furcation defects', J Clin Periodontol, 28: 730-40. Artzi, Z., H. Tal, O. Platner, N. Wasersprung, E. Weinberg, S. Slutzkey, N. Gozali, G. Carmeli, R. Herzberg, and A. Kozlovsky. 2015. 'Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: a 1-year retrospective study', J Clin Periodontol, 42: 547-56. Asa'ad, F., G. Pagni, S. P. Pilipchuk, A. B. Gianni, W. V. Giannobile, and G. Rasperini. 2016. '3D-Printed Scaffolds and Biomaterials: Review of Alveolar Bone Augmentation and Periodontal Regeneration Applications', Int J Dent, 2016: 1239842. Association, World Medical. 2013. 'World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects', JAMA, 310: 2191-94. Avila-Ortiz, Gustavo, Juan G. De Buitrago, and Michael S. Reddy. 2015. 'Periodontal Regeneration – Furcation Defects: A Systematic Review From the AAP Regeneration Workshop', Journal of Periodontology, 86: S108-S30. Bose, Susmita, Sahar Vahabzadeh, and Amit Bandyopadhyay. 2013. 'Bone tissue engineering using 3D printing', Materials Today, 16: 496-504. Bosshardt, D. D. 2008. 'Biological mediators and periodontal regeneration: a review of enamel matrix proteins at the cellular and molecular levels', J Clin Periodontol, 35: 87-105. Bower, Robert C. 1979. 'Furcation Morphology Relative to Periodontal Treatment: Furcation Entrance Architecture', Journal of Periodontology, 50: 23-27. Casarin, Renato Corrêa Viana, Érica Del Peloso Ribeiro, Francisco Humberto Nociti, Antônio Wilson Sallum, Enilson Antônio Sallum, Gláucia Maria Bovi Ambrosano, and Márcio Zaffalon Casati. 2008. 'A double-blind randomized clinical evaluation of enamel matrix derivative proteins for the treatment of proximal class-II furcation involvements', Journal of Clinical Periodontology, 35: 429-37. Chang, P. C., H. T. Luo, Z. J. Lin, W. C. Tai, C. H. Chang, Y. C. Chang, D. L. Cochran, and M. H. Chen. 2021a. 'Preclinical evaluation of a 3D-printed hydroxyapatite/poly(lactic-co-glycolic acid) scaffold for ridge augmentation', J Formos Med Assoc, 120: 1100-07. ———. 2021b. 'Regeneration of critical-sized mandibular defect using a 3D-printed hydroxyapatite-based scaffold: An exploratory study', J Periodontol, 92: 428-35. Chen, Tsung-Hung, Yu-Kang Tu, Chia-Chen Yen, and Hsein-Kun Lu. 2013. 'A systematic review and meta-analysis of guided tissue regeneration/osseous grafting for the treatment of Class II furcation defects', Journal of Dental Sciences, 8: 209-24. Eickholz, P., and E. Hausmann. 1997. 'Evidence for healing of class II and III furcations after GTR therapy: digital subtraction and clinical measurements', J Periodontol, 68: 636-44. El Kholy, K., R. Lazarin, S. F. M. Janner, K. Faerber, R. Buser, and D. Buser. 2019. 'Influence of surgical guide support and implant site location on accuracy of static Computer-Assisted Implant Surgery', Clin Oral Implants Res, 30: 1067-75. Fleischer, H. C., J. T. Mellonig, W. K. Brayer, J. L. Gray, and J. D. Barnett. 1989. 'Scaling and root planing efficacy in multirooted teeth', J Periodontol, 60: 402-9. Gher, M. W., Jr., and R. W. Dunlap. 1985. 'Linear variation of the root surface area of the maxillary first molar', J Periodontol, 56: 39-43. Graziani, F., S. Gennai, M. Petrini, L. Bettini, and M. Tonetti. 2019. 'Enamel matrix derivative stabilizes blood clot and improves clinical healing in deep pockets after flapless periodontal therapy: A Randomized Clinical Trial', J Clin Periodontol, 46: 231-40. Hammarström, L., Blomlof, L. Lindskog, S. 1995. 'Composition containing enamel matrix from tooth germs for inducing binding between living mineralized tissue parts.' In. Hamp, Sven-Erik, Sture Nyman, and Jan Lindhe. 1975. 'Periodontal treatment of multi rooted teeth', Journal of Clinical Periodontology, 2: 126-35. Hannink, G., and J. J. Arts. 2011. 'Bioresorbability, porosity and mechanical strength of bone substitutes: what is optimal for bone regeneration?', Injury, 42 Suppl 2: S22-5. Hoffmann, Thomas, Steffen Richter, Joerg Meyle, Jose R. Gonzales, Bernd Heinz, Mehrdad Arjomand, Anton Sculean, Elmar Reich, Karin Jepsen, Soren Jepsen, and Rolf-Hasso Boedeker. 2006. 'A randomized clinical multicentre trial comparing enamel matrix derivative and membrane treatment of buccal class II furcation involvement in mandibular molars. Part III: patient factors and treatment outcome', Journal of Clinical Periodontology, 33: 575-83. Hou, G. L., C. C. Hung, Y. S. Yang, T. Y. Shieh, and C. C. Tsai. 2003. 'Radiographic alveolar bone loss in untreated Taiwan Chinese subjects with adult periodontitis measured by the digital scanning radiographic image analysis method', Dentomaxillofac Radiol, 32: 104-8. Houser, B. E., J. T. Mellonig, M. A. Brunsvold, D. L. Cochran, R. M. Meffert, and M. E. Alder. 2001. 'Clinical evaluation of anorganic bovine bone xenograft with a bioabsorbable collagen barrier in the treatment of molar furcation defects', Int J Periodontics Restorative Dent, 21: 161-9. Huang, R. Y., C. D. Lin, M. S. Lee, C. L. Yeh, E. C. Shen, C. Y. Chiang, H. C. Chiu, and E. Fu. 2007. 'Mandibular disto-lingual root: a consideration in periodontal therapy', J Periodontol, 78: 1485-90. Jaiswal, R., and V. Deo. 2013. 'Evaluation of the effectiveness of enamel matrix derivative, bone grafts, and membrane in the treatment of mandibular Class II furcation defects', Int J Periodontics Restorative Dent, 33: e58-64. Jakus, A. E., A. L. Rutz, and R. N. Shah. 2016. 'Advancing the field of 3D biomaterial printing', Biomed Mater, 11: 014102. Jepsen, Søren, Stefano Gennai, Josefine Hirschfeld, Zamira Kalemaj, Jacopo Buti, and Filippo Graziani. 2020. 'Regenerative surgical treatment of furcation defects: A systematic review and Bayesian network meta‐analysis of randomized clinical trials', Journal of Clinical Periodontology, 47: 352-74. Jepsen, S., J. Eberhard, D. Herrera, and I. Needleman. 2002. 'A systematic review of guided tissue regeneration for periodontal furcation defects. What is the effect of guided tissue regeneration compared with surgical debridement in the treatment of furcation defects?', J Clin Periodontol, 29 Suppl 3: 103-16; discussion 60-2. Jepsen, S., B. Heinz, K. Jepsen, M. Arjomand, T. Hoffmann, S. Richter, E. Reich, A. Sculean, J. R. Gonzales, R. H. Bodeker, and J. Meyle. 2004. 'A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal Class II furcation involvement in mandibular molars. Part I: Study design and results for primary outcomes', J Periodontol, 75: 1150-60. Karageorgiou, V., and D. Kaplan. 2005. 'Porosity of 3D biomaterial scaffolds and osteogenesis', Biomaterials, 26: 5474-91. Kinaia, B. M., J. Steiger, A. L. Neely, M. Shah, and M. Bhola. 2011. 'Treatment of Class II molar furcation involvement: meta-analyses of reentry results', J Periodontol, 82: 413-28. Langer, B., S. D. Stein, and B. Wagenberg. 1981. 'An evaluation of root resections. A ten-year study', J Periodontol, 52: 719-22. Lee, C. H., J. Hajibandeh, T. Suzuki, A. Fan, P. Shang, and J. J. Mao. 2014. 'Three-dimensional printed multiphase scaffolds for regeneration of periodontium complex', Tissue Eng Part A, 20: 1342-51. Loos, B., K. Nylund, N. Claffey, and J. Egelberg. 1989. 'Clinical effects of root debridement in molar and non-molar teeth. A 2-year follow-up', J Clin Periodontol, 16: 498-504. Meyle, J., J. R. Gonzales, R. H. Bodeker, T. Hoffmann, S. Richter, B. Heinz, M. Arjomand, E. Reich, A. Sculean, K. Jepsen, and S. Jepsen. 2004. 'A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal class II furcation involvement in mandibular molars. Part II: secondary outcomes', J Periodontol, 75: 1188-95. Miron, R. J., M. Dard, and M. Weinreb. 2015. 'Enamel matrix derivative, inflammation and soft tissue wound healing', J Periodontal Res, 50: 555-69. Miron, R. J., A. Sculean, D. L. Cochran, S. Froum, G. Zucchelli, C. Nemcovsky, N. Donos, S. P. Lyngstadaas, J. Deschner, M. Dard, A. Stavropoulos, Y. Zhang, L. Trombelli, A. Kasaj, Y. Shirakata, P. Cortellini, M. Tonetti, G. Rasperini, S. Jepsen, and D. D. Bosshardt. 2016. 'Twenty years of enamel matrix derivative: the past, the present and the future', J Clin Periodontol, 43: 668-83. Muschler, G. F., C. Nakamoto, and L. G. Griffith. 2004. 'Engineering principles of clinical cell-based tissue engineering', J Bone Joint Surg Am, 86: 1541-58. Nesic, D., B. M. Schaefer, Y. Sun, N. Saulacic, and I. Sailer. 2020. '3D Printing Approach in Dentistry: The Future for Personalized Oral Soft Tissue Regeneration', J Clin Med, 9. Nibali, L., A. Akcali, and S. G. Rudiger. 2019. 'The importance of supportive periodontal therapy for molars treated with furcation tunnelling', J Clin Periodontol, 46: 1228-35. Nyman, Sture. 1991. 'Bone regeneration using the principle of guided tissue regeneration', Journal of Clinical Periodontology, 18: 494-98. Parashis, A. O., A. Anagnou-Vareltzides, and N. Demetriou. 1993. 'Calculus removal from multirooted teeth with and without surgical access', Journal of Clinical Periodontology, 20: 63-68. Park, C. H., K. H. Kim, Y. M. Lee, W. V. Giannobile, and Y. J. Seol. 2017. '3D Printed, Microgroove Pattern-Driven Generation of Oriented Ligamentous Architectures', Int J Mol Sci, 18. Park, C. H., K. H. Kim, Y. M. Lee, and Y. J. Seol. 2016. 'Advanced Engineering Strategies for Periodontal Complex Regeneration', Materials (Basel), 9. Park, C. H., H. F. Rios, Q. Jin, M. E. Bland, C. L. Flanagan, S. J. Hollister, and W. V. Giannobile. 2010. 'Biomimetic hybrid scaffolds for engineering human tooth-ligament interfaces', Biomaterials, 31: 5945-52. Pereira, Taciana, Margaret E Prendergast, and Ricky Solorzano. 2018. 'State of the art biofabrication technologies and materials for bone tissue engineering', Journal of 3D Printing in Medicine, 2: 103-13. Pontoriero, R., J. Lindhe, S. Nyman, T. Karring, E. Rosenberg, and F. Sanavi. 1989. 'Guided tissue regeneration in the treatment of furcation defects in mandibular molars. A clinical study of degree III involvements', J Clin Periodontol, 16: 170-4. Rasperini, G., J. Majzoub, L. Tavelli, E. Limiroli, A. Katayama, S. Barootchi, R. Hill, and H. L. Wang. 2020. 'Management of Furcation-Involved Molars: Recommendation for Treatment and Regeneration', Int J Periodontics Restorative Dent, 40: e137-e46. Rasperini, G., S. P. Pilipchuk, C. L. Flanagan, C. H. Park, G. Pagni, S. J. Hollister, and W. V. Giannobile. 2015. '3D-printed Bioresorbable Scaffold for Periodontal Repair', J Dent Res, 94: 153S-7S. Reynolds, Mark A. 2014. 'Modifiable risk factors in periodontitis: at the intersection of aging and disease', Periodontology 2000, 64: 7-19. Sallum, E. A., F. V. Ribeiro, K. S. Ruiz, and A. W. Sallum. 2019. 'Experimental and clinical studies on regenerative periodontal therapy', Periodontol 2000, 79: 22-55. Sanz, Mariano, Karin Jepsen, Peter Eickholz, and Søren Jepsen. 2015. 'Clinical concepts for regenerative therapy in furcations', Periodontology 2000, 68: 308-32. Shiau, H. J., and M. A. Reynolds. 2010a. 'Sex differences in destructive periodontal disease: a systematic review', J Periodontol, 81: 1379-89. ———. 2010b. 'Sex differences in destructive periodontal disease: exploring the biologic basis', J Periodontol, 81: 1505-17. Simonpietri-C, Jeannette J., Arthur B. Novaes Jr., Eraldo L. Batista Jr., and Eduardo J. Feres Filho. 2000. 'Guided Tissue Regeneration Associated With Bovine-Derived Anorganic Bone in Mandibular Class II Furcation Defects. 6-Month Results at Re-Entry', Journal of Periodontology, 71: 904-11. Slavkin, H. C., and P. M. Bartold. 2006. 'Challenges and potential in tissue engineering', Periodontol 2000, 41: 9-15. Slots, J., and M. Ting. 1999. 'Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment', Periodontol 2000, 20: 82-121. Stoop, C. C., K. Chatzivasileiou, W. E. R. Berkhout, and D. Wismeijer. 2019. 'Marginal and internal fit of 3D printed resin graft substitutes mimicking alveolar ridge augmentation: An in vitro pilot study', PLoS One, 14: e0215092. Sulaiman, T. A. 2020. 'Materials in digital dentistry-A review', J Esthet Restor Dent, 32: 171-81. Svardstrom, G., and J. L. Wennstrom. 1996. 'Prevalence of furcation involvements in patients referred for periodontal treatment', J Clin Periodontol, 23: 1093-9. Tartaglia, G. M., A. Mapelli, C. Maspero, T. Santaniello, M. Serafin, M. Farronato, and A. Caprioglio. 2021. 'Direct 3D Printing of Clear Orthodontic Aligners: Current State and Future Possibilities', Materials (Basel), 14. Toback, G. A., M. A. Brunsvold, P. V. Nummikoski, L. B. Masters, J. T. Mellonig, and D. L. Cochran. 1999. 'The accuracy of radiographic methods in assessing the outcome of periodontal regenerative therapy', J Periodontol, 70: 1479-89. Tonetti, M. S., N. P. Lang, P. Cortellini, J. E. Suvan, P. Adriaens, D. Dubravec, A. Fonzar, I. Fourmousis, L. Mayfield, R. Rossi, M. Silvestri, C. Tiedemann, H. Topoll, T. Vangsted, and B. Wallkamm. 2002. 'Enamel matrix proteins in the regenerative therapy of deep intrabony defects', J Clin Periodontol, 29: 317-25. Tonetti, Maurizio S., Giovanpaolo Pini-Prato, and Pierpaolo Cortellini. 1993. 'Periodontal Regeneration of Human Intrabony Defects. IV. Determinants of Healing Response', Journal of Periodontology, 64: 934-40. van Noort, R. 2012. 'The future of dental devices is digital', Dent Mater, 28: 3-12. Vaquette, C., W. Fan, Y. Xiao, S. Hamlet, D. W. Hutmacher, and S. Ivanovski. 2012. 'A biphasic scaffold design combined with cell sheet technology for simultaneous regeneration of alveolar bone/periodontal ligament complex', Biomaterials, 33: 5560-73. Woodard, J. R., A. J. Hilldore, S. K. Lan, C. J. Park, A. W. Morgan, J. A. Eurell, S. G. Clark, M. B. Wheeler, R. D. Jamison, and A. J. Wagoner Johnson. 2007. 'The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity', Biomaterials, 28: 45-54. Ya-Ting Jhang, Yi-Wen Chen, Chen-Ying Wang, Che-Chang Tu, Cheing-Meei Liu, Mark Yen-Ping Kuo, and Po-Chun Chang. 2019. 'Association Between Initial Clinical Parameters and the Outcome of Non-Surgical Periodontal Therapy: Patient-, Tooth-, and Site-level Analyses', Journal of Periodontics and Implant Dentistry, 2: 8. Yu, H. C., N. Y. Su, J. Y. Huang, S. S. Lee, and Y. C. Chang. 2017. 'Trends in the prevalence of periodontitis in Taiwan from 1997 to 2013: A nationwide population-based retrospective study', Medicine (Baltimore), 96: e8585. Yu, N., T. Nguyen, Y. D. Cho, N. M. Kavanagh, I. Ghassib, and W. V. Giannobile. 2019. 'Personalized scaffolding technologies for alveolar bone regenerative medicine', Orthod Craniofac Res, 22 Suppl 1: 69-75. Yukna, R. A., and J. T. Mellonig. 2000. 'Histologic evaluation of periodontal healing in humans following regenerative therapy with enamel matrix derivative. A 10-case series', J Periodontol, 71: 752-9. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/80480 | - |
| dc.description.abstract | "研究目的 在下顎大臼齒牙周分叉缺損的牙周再生手術成功率仍是牙周再生一大挑戰，本研究旨在製作客製化三維組織支架用以有效率促進齒槽骨再生。 研究材料與方法 本實驗第一部分是收集臺大醫院牙周病科在2017年2月到2020年12月所進行的下顎大臼齒牙根分岔處牙周再生手術的病例，牙周再生手術材料骨粉包含自體骨骨粉、異體骨骨粉及異種牛骨粉(DBBM, Deproteinized bovine bone mineral)搭配再生凝膠或牙周再生膜的應用。牙根分叉處骨缺損分為單純牙根分岔處缺損與合併牙根分岔與牙周齒槽骨周圍缺損兩大類，並比對手術前與手術後六個月的臨床根尖放射線影像上牙根分岔處，齒頸部到牙根分岔處齒槽骨線性高度的變化，以牙根分岔到新生成齒槽骨線性高度變化所占牙根分岔點到牙根分岔骨缺損的距離作為線性再生骨高度的比例，另外以牙根分岔到新生成齒槽骨線性高度變化所占患齒近心側與遠心側齒槽骨高度的中心點的比例做為校正骨再生比例。我們以齒槽骨高度的變化、骨再生比例、校正再生比例，三種評估方式作為牙周骨再生效果的評估。 實驗第二部分是評估三維快速成型生物支架在實驗豬下顎骨模型貼合度，利用實驗豬模擬下顎大臼齒牙根分叉的臨床破壞，並利用錐狀電腦斷層掃描實驗豬下顎骨模型後搭配三維影像編輯軟體設計骨缺損模型後，我們利用此模型進行模擬臨床客製化牙根分岔骨支架列印，用三維光固化列印技術列印樹脂模型作為對照組，同時羥基磷灰石彈性骨墨水採用生物列印方式印出三維骨支架。將樹脂骨塊與骨支架分別放回下顎豬骨缺損後，使用微米電腦斷層掃描後，利用影像軟體檢驗此骨生物支架與實驗豬下顎骨缺損到三維骨支架外緣的線性貼合度與比對我們電腦設計的骨塊形狀與三維骨支架相比的體積差異性。 結果 從臨床根尖片可以看出，我們利用手術前後牙根分岔處齒槽骨再生影像的變化，作為評估牙根分岔牙周再生手術的成功指標。在單純的牙根分岔處缺損，在影像上線性再生骨高度為1.45±1.15毫米，骨再生比例為50±40%與校正骨再生比例為39±30%。三種骨粉的使用當中，使用異種牛骨粉(DBBM, Deproteinized bovine bone mineral)達64±38%的骨再生效果，相較自體骨骨粉(Autogenous bone)的16±25%與異體骨骨粉(FDBA) 52±34%有較顯著的成果。女性病患相比於男性病患有顯著更好的牙周再生的成果。 在合併角狀骨缺損和牙根分岔處缺損，在影像上線性再生骨高度為1.35±1.25毫米，骨再生比例為50±34%與校正骨再生比例為38±32%。使用再生凝膠(EMD)較引導骨再生手術牙周再生膜有更顯著性的牙周再生效果。 在實驗豬下顎骨實驗之中，利用電腦斷層分析掃描後的羥基磷灰石生物支架對比電腦設計生物支架線性邊緣貼合度為 82.99±21.12% 和體積密合度85.58±5.48%。 結論 目前臨床牙根分岔再生大約有1.4mm 或40%的再生效果。在三維列印骨支架貼合實驗中，骨生物支架相比樹脂生物支架線性邊緣貼合度為82.99% 和體積密合度85.58%。" | zh_TW |
| dc.description.provenance | Made available in DSpace on 2022-11-24T03:07:31Z (GMT). No. of bitstreams: 1 U0001-1910202116200200.pdf: 2257946 bytes, checksum: c9a954aa0415eb6e83d31ac5d1a66763 (MD5) Previous issue date: 2021 | en |
| dc.description.tableofcontents | 口試委員會審定書 1 誌謝 2 中文摘要 3 Abstract 5 Chapter 1: Introduction 10 1.1. Periodontitis 10 1.2. Furcation anatomy and classification in molars 13 1.3. Treatment strategies for furcation involvement 15 1.3.1 Guided tissue regeneration 18 1.3.2 Enamel matrix derivatives 20 1.4. Comparison between enamel matrix derivatives and guided tissue regeneration 21 1.5. Current concerns of regeneration strategies 22 1.6. Three-dimensional printing technology in dentistry 23 1.6.1. Digital dentistry 23 1.6.2. Common 3D printing technologies 25 1.6.3. Tissue engineering scaffold 27 1.6.4. Clinical application of 3D-printed scaffolds for periodontal regeneration 31 Chapter 2: Research Goal 32 2.1 Hypotheses 33 2.2 Specific Aims 34 Chapter 3: Materials and Methods 35 3.1 Clinical outcomes of furcation defect regeneration 35 3.1.1 Ethical approval and the selection of charts 36 3.1.2 Data stratification 38 3.1.3 Analysis of radiographs and the definition of parameters 39 3.1.4 Statistical analysis 41 3.2 Experimental furcation defects in pig jaws 42 3.2.1 Defect creation 43 3.2.2 Image-based design for furcation defect regeneration 44 3.2.3 Preparation of resin blocks 45 3.2.4 Preparation of a HA-based porous scaffold 46 3.2.5 Radiographic analysis of scaffold and bone block statistical analysis 48 Chapter 4: Results 49 4.1 Furcation defect regeneration 49 4.2 Combined furcation-angular defects 52 4.3 Fitness of 3D-printed HA-based scaffold in a pig jaw furcation defect model 54 4.3.1 Characterization of the 3D-printed scaffolds 54 4.3.2 Scaffold adaptation in the furcation defects 55 5 Chapter 5: Discussion 56 5.1 Clinical outcomes of regeneration 56 5.2 Three-dimensionally-printed HA scaffolds 62 Chapter 6: Conclusion 65 Tables and Figures 66 References 87 | |
| dc.language.iso | en | |
| dc.subject | 三維列印 | zh_TW |
| dc.subject | 牙根分岔骨缺損 | zh_TW |
| dc.subject | 組織支架 | zh_TW |
| dc.subject | 骨再生 | zh_TW |
| dc.subject | tissue scaffold | en |
| dc.subject | three dimensional printing | en |
| dc.subject | bone regeneration | en |
| dc.subject | furcation defects | en |
| dc.title | 牙根分岔再生探討: 現行臨床治療策略功效評估與快速列印三維羥基磷灰石生物支架設計 | zh_TW |
| dc.title | Furcation Defect Regeneration: The Outcome of Current Treatment Strategies and the Development of a Rapidly Prototyped Hydroxyapatite Scaffold | en |
| dc.date.schoolyear | 110-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 郭彥彬(Hsin-Tsai Liu),侯欣翰(Chih-Yang Tseng),王進瑋 | |
| dc.subject.keyword | 牙根分岔骨缺損,組織支架,骨再生,三維列印, | zh_TW |
| dc.subject.keyword | furcation defects,tissue scaffold,bone regeneration,three dimensional printing, | en |
| dc.relation.page | 93 | |
| dc.identifier.doi | 10.6342/NTU202103882 | |
| dc.rights.note | 同意授權(限校園內公開) | |
| dc.date.accepted | 2021-11-16 | |
| dc.contributor.author-college | 醫學院 | zh_TW |
| dc.contributor.author-dept | 臨床牙醫學研究所 | zh_TW |
| 顯示於系所單位： | 臨床牙醫學研究所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| U0001-1910202116200200.pdf 授權僅限NTU校內IP使用（校園外請利用VPN校外連線服務） | 2.21 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。