請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/77635完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 陳厚銘,任立中 | |
| dc.contributor.author | Ya-Wen Yang | en |
| dc.contributor.author | 楊雅雯 | zh_TW |
| dc.date.accessioned | 2021-07-10T22:12:51Z | - |
| dc.date.available | 2021-07-10T22:12:51Z | - |
| dc.date.copyright | 2018-07-17 | |
| dc.date.issued | 2018 | |
| dc.date.submitted | 2018-07-09 | |
| dc.identifier.citation | 財團法人醫院評鑑暨醫療品質策進會,醫病溝通再進化~ 醫病共享決策,http://www.jct.org.tw/epaper/201605/2016%E9%86%AB%E7%97%85%E5%85%B1%E4%BA%AB%E6%B1%BA%E7%AD%96.pdf,搜尋日期:2018年06月23日。
勤業眾信,2016,生物相似性藥品商機觀察從全球發展看台灣機會,https://www2.deloitte.com/content/dam/Deloitte/tw/Documents/life-sciences-health-care/tw-biosimilars-inglobal-markets.pdf,搜尋日期:2018年06月23日。 Aguilar, Francis.1967. Scanning the Business Environment. New York: Macmillan. Armstrong AW., Robertson AD., Wu J., Schupp C., and Lebwohl MG. 2013. Undertreatment, Treatment Trends, and Treatment Dissatisfaction Among Patients With Psoriasis and Psoriatic Arthritis in the United StatesFindings From the National Psoriasis Foundation Surveys, 2003-2011. JAMA Dermatol, 149(10):1180-1185 Bain & Company. 2017. Category Focus Rewards Biopharma Shareholders. http://www.bain.com/publications/articles/category-focus-rewards-biopharma-shareholders-invivo.aspx. Accessed Jun. 23, 2018 Barksdale, HC., and Harris Jr., CE. 1982. Portfolio Analysis and the Product Life Cycle. Long Range Planning. 15 (6): 74-83. Belloni, A., Morgan D., and Paris V. 2016. Pharmaceutical Expenditure And Policies: Past Trends And Future Challenges. OECD Health Working Papers, No. 87. OECD Publishing, Paris. Bhasin, H. 2018. BCG Matrix or BCG analysis. https://www.marketing91.com/bcg-matrix/. Accessed Jun. 23, 2018 Business Wire. 2017. Global Immunology Drugs Market to 2022 - Increasing Prevalence, Repositioning Opportunities and Strong Uptake of Interleukin Receptor Inhibitors to Drive Growth - Research and Markets. https://www.businesswire.com/news/home/20170621005718/en/Global-Immunology-Drugs-Market-2022---Increasing. Accessed Jun. 23, 2018 CNBC. 2018. To make copycat drugs more competitive, the FDA is taking a harder look at the originals. https://www.cnbc.com/2018/03/28/to-make-biosimilars-more-competitive-fda-takes-harder-look-at-the-originals.html. Accessed Jun. 23, 2018 Dieleman, JL., Squires, E., Bui, AL. 2017. Factors Associated With Increases in US Health Care Spending, 1996-2013. JAMA, 318(17):1668-1678 EvaluatePharma. 2017. World Preview 2017, Outlook to 2022. http://info.evaluategroup.com/rs/607-YGS-364/images/WP17.pdf. Accessed Jun. 23, 2018. FiercePharma. 2017. Pfizer faces renewed bid for Xalkori royalties as appeals panel revives NYT lawsuit. https://www.fiercepharma.com/pharma/appeals-court-rejects-previous-pfizer-victory-xalkori-royalty-case. Accessed Jun. 23, 2018 Generics and Biosimilars Initiatives. 2011. The history of the US biosimilar regulatory pathway. http://www.gabionline.net/Biosimilars/General/The-history-of-the-US-biosimilar-regulatory-pathway. Accessed Jun. 23, 2018 GlobalData. 2017. Lupus market will reach $3.2 billion by 2025, driven by new first-in-class products. https://www.globaldata.com/lupus-market-will-reach-3-2-billion-2025-driven-new-first-class-products-says-globaldata/. Accessed Jun. 23, 2018. IgeaHub. 2008. Top 10 Pharmaceutical Companies 2018. https://www.igeahub.com/2018/03/06/top-10-pharmaceutical-companies-2018/. Accessed Jun. 23, 2018. Imperial College London. 2003. British Scientists receive Lasker Prize for discovering new treatment for rheumatoid arthritis. https://www.imperial.ac.uk/college.asp?P=4393. Accessed Jun. 23, 2018. Johnson and Johnson. 2018. Johnson and Johnson 2017 Annual Report. Mar 2018. Kievit W., Fransen J., de Waal Malefijt MC., den Broeder AA., and van Riel PL. 2013. Treatment changes and improved outcomes in RA: an overview of a large inception cohort from 1989 to 2009. Rheumatology, 52(8):1500–1508 Kim BS., Lee WK., Pak K., Han J., Kim GW., Kim HS., Ko HC., Kim MB., and Kim SJ. 2018. Ustekinumab treatment is associated with decreased systemic and vascular inflammation in patients with moderate to severe psoriasis: Feasibility study using 18F-fluorodeoxyglucose positron emission tomography-computed tomography. J Am Acad Dermatol, S0190-9622(18): 30461-4 Kim HR. 2014. Formulation of a Success Model in Pharmaceutical R&D: Efficient Innovation Model. SAGE Open, January-March: 1–9 Mestre-Ferrandiz, J., Sussex, J., Towse, A. 2012. The R&D cost of a new medicine. United Kingdom: Office of Health Economics Mantovani, L., Medaglia, M., Piacentini, M., Tricca, M., Vena GA., Vozza, A., Castellino,G., and Roccia, A. 2016. Burden of Moderate-to-Severe Plaque Psoriasis and New Therapeutic Approaches (Secukinumab): An Italian Perspective. Dermatol Ther (Heidelb), 6(2): 151–167. Pfizer. 2018. 2017 Pfizer Annual Report to Shareholders. https://investors.pfizer.com/financials/annual-reports/default.aspx. Accessed Jun. 23, 2018. PMLiVE. 2017. Top 15 pharma companies by immunology sales. http://www.pmlive.com/top_pharma_list/immunology_revenues. Accessed Jun. 23, 2018. Pons-Estel, GJ., Ugarte-Gil, MF., Alarcón, GS. 2017. Epidemiology of systemic lupus erythematosus. Exp Rev Clin Immunol,13(8):799-814 Porter, M. 1979. How competitive forces shape strategy. Harvard Business Review, March/April 1979 Porter, M. 1985. Competitive Advantage: Creating and Sustaining Superior Performance. New York.: Simon and Schuster. PPD. 2018. About drug development. http://www.ppdi.com/About/About-Drug-Discovery-and-Development. Accessed Jun. 23, 2018. PR Newswire. 2017. The Future of Market Access in Europe. https://www.prnewswire.com/news-releases/the-future-of-market-access-in-europe-300563288.html. Accessed Jun. 23, 2018. Raaby L., Ahlehoff O., and de Thurah, A. 2017. Psoriasis and cardiovascular events: updating the evidence. Archives of Dermatological Research, 309 (3):225–228 Schiestl, M., Zabransky, M. and Sörgel F. 2017. Ten years of biosimilars in Europe: development and evolution of the regulatory pathways. Drug Des Devel Ther. 2017; 11: 1509–1515. Science. 2018. Drug Discovery and Biotechnology Trends: Recent Developments in Drug Discovery: Improvements in Efficiency. http://www.sciencemag.org/site/products/ddbt_0207_Final.xhtml. Accessed Jun. 23, 2018. Siegel, JF. 2017. 2017 Biosimilar Approvals in Europe. https://www.biologicsblog.com/2017-biosimilar-approvals-in-europe. Accessed Jun. 23, 2018. The Center for Biosimilars. 2018. New Efforts to Encourage Biosimilar Use in Finland, Switzerland, and France. http://www.centerforbiosimilars.com/news/new-efforts-to-encourage-biosimilar-use-in-finland-switzerland-france. Accessed Jun. 23, 2018. Trish, E., Joyce G., Goldman DP. 2014. Specialty drug spending trends among Medicare and Medicare Advantage enrollees, 2007-11. Health Aff (Millwood), 33(11):2018-24. Wikipedia, the free encyclopedia. 2018. Biosimilar. https://en.wikipedia.org/wiki/Biosimilar. Accessed Jun. 23, 2018. Wikipedia, the free encyclopedia. 2018. Growth–share matrix. https://en.wikipedia.org/wiki/Growth%E2%80%93share_matrix. Accessed Jun. 23, 2018. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/77635 | - |
| dc.description.abstract | 全球醫藥市場中,過去二十年來,免疫發炎疾病治療領域因為生物製劑的蓬勃發展,不斷地有新的、有療效的藥物上市,使病人可以得到妥善的治療和良好的預後,也帶動了此市場的持續成長。擁有治療免疫發炎疾病生物製劑的跨國研發型藥廠更是在過去二十年得利於此市場的高獲利和高成長。但是隨著越來越多新的藥物競爭者的進入市場,再加上隨著一些原廠生物製劑專利過期,相對較低價的生物相似藥逐漸滲透入市場,免疫發炎疾病治療領域的競爭強度越來越劇烈。跨國研發型藥廠極需要重新檢視自家公司在此疾病領域的策略布局,制定創新、變革性的發展策略,使公司能夠持續在此領域永續經營和成長。本研究分析全球醫藥市場和免疫發炎疾病治療領域市場現況,並以實際個案A公司做深入的個案研究,最後提出了三個轉型發展策略,以解決公司中長期永續成長的需求。 | zh_TW |
| dc.description.abstract | In the past twenty years, with the increasing entry of similar or different mechanism of action (MOA) effective biologic drugs into immunology therapeutic area, patients suffering from immunologic disease have been properly treated and seen dramatically improved outcomes. As a result, the immunology disease market has been continuously growing in the global pharmaceutical market, and multinational pharmaceutical companies owning biologics treating immunologic diseases have been enjoying high growth and high profitability in the market. However, with more and more competitors entering the market, and the penetration of cheaper biosimilars after biologics come off patent, the market has become fiercely competitive. There is an urgent need for multinational pharmaceutical companies to revisit their strategies in immunology therapeutic area, and formulate innovative and transformative development strategies, leading to the sustainable growth in this market.
The objective of this study is to analyze the current market situation of global pharmaceutical industry and immunology therapeutic area, and conduct an in-depth case study of the A company, and finally propose three transformational development strategies to address mid- and long-term need of sustained growth of the A company. | en |
| dc.description.provenance | Made available in DSpace on 2021-07-10T22:12:51Z (GMT). No. of bitstreams: 1 ntu-107-P05746017-1.pdf: 2889428 bytes, checksum: 5405859e3823fd9766c08039bc2b5c0e (MD5) Previous issue date: 2018 | en |
| dc.description.tableofcontents | 目錄
口試委員審定書 ii 誌謝 iii 中文摘要 iv ABSTRACT v 目錄 vi 圖目錄 viii 表目錄 ix 第一章 緒論 1 第一節、研究背景與動機 1 第二節、研究目的 2 第三節、研究方法與流程 2 第四節、論文架構 3 第二章 文獻探討 5 第一節、PEST分析 5 第二節、五力分析 6 第三節、價值鏈分析模型 7 第四節、BCG矩陣 8 第三章 全球藥業暨免疫發炎疾病醫藥產業分析 10 第一節、跨國研發型藥廠現狀概述 10 第二節、免疫發炎性疾病治療領域和市場概述 12 第三節、免疫發炎性疾病醫藥產業外部環境 15 第四章 個案研究 21 第一節、個案A公司概況 21 第二節、個案A公司免疫發炎疾病治療領域之產業競爭 23 第三節、個案A公司的基本優勢 27 第四節、個案A公司免疫疾病治療領域策略選擇分析 31 第五章 結論與建議 44 第一節、研究結論 44 第二節、研究建議 45 參考文獻 48 圖目錄 圖1-1 研究方法及流程3 圖2-1 PEST分析模型5 圖2-2 波特五力分析模型6 圖2-3 價值鏈分析模型7 圖2-4 BCG矩陣8 圖3-1 2017 Revenue of Top 10 pharmaceutical company10 圖3-2 2016 Revenue and estimated CAGR of major therapeutic areas11 圖3-3 免疫發炎性疾病種類與核可治療的生物製劑數量14 圖3-4 每個Medicare 保險受益人的annual specialty drugs spending17 圖3-5 藥物研發過程18 圖3-6 重度乾癬的治療目標隨著新藥逐漸提高19 圖4-1 個案A 公司組織架構圖22 圖4-2 R and D Share of Revenue 201728 圖4-3 在醫師客戶心中MSLs的專業度表現29 圖4-4 僵直性脊椎炎病患疾病管理digital tool 30 圖4-5 The cost of drug discovery and development 34 圖4-6 免疫發炎疾病病患的醫療過程 (Patient Journey)39 圖4-7 A公司免疫發炎疾病治療領域業務BCG 矩陣分布42 圖4-8 A公司免疫發炎疾病治療領域業務BCG 矩陣策略布局43 表目錄 表4-1 競爭者之績效表現和成長因關鍵因素分析23 | |
| dc.language.iso | zh-TW | |
| dc.subject | 病患為中心 | zh_TW |
| dc.subject | 免疫發炎疾病治療領域 | zh_TW |
| dc.subject | 生物製劑 | zh_TW |
| dc.subject | 轉型策略 | zh_TW |
| dc.subject | Biologics | en |
| dc.subject | Immunology therapeutic area | en |
| dc.subject | Transformational strategies | en |
| dc.subject | Patient-centric | en |
| dc.title | 跨國藥廠在免疫疾病治療領域之發展策略研究—以A公司為例 | zh_TW |
| dc.title | The Development Strategy of Immunology Therapeutic Area in Multinational Pharmaceutical Company
—The A Company as a Case Study | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 106-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 許嘉文,陳聿宏 | |
| dc.subject.keyword | 免疫發炎疾病治療領域,生物製劑,轉型策略,病患為中心, | zh_TW |
| dc.subject.keyword | Immunology therapeutic area,Biologics,Transformational strategies,Patient-centric, | en |
| dc.relation.page | 52 | |
| dc.identifier.doi | 10.6342/NTU201801328 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2018-07-10 | |
| dc.contributor.author-college | 管理學院 | zh_TW |
| dc.contributor.author-dept | 國際企業管理組 | zh_TW |
| 顯示於系所單位: | 國際企業管理組 | |
文件中的檔案:
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-107-P05746017-1.pdf 未授權公開取用 | 2.82 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。
