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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 鄭如忠 | |
dc.contributor.author | Nishiki Uchibe | en |
dc.contributor.author | 内部錦 | zh_TW |
dc.date.accessioned | 2021-06-17T07:37:10Z | - |
dc.date.available | 2024-04-01 | |
dc.date.copyright | 2019-04-01 | |
dc.date.issued | 2019 | |
dc.date.submitted | 2019-03-28 | |
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dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/73477 | - |
dc.description.abstract | 本研究利用高效率的交替式反應,合成出具有光化學受體的樹枝狀 poly(urea/maloamide)s 結構,並應用於螢光感測用途。首先透過合成具有高度反應 選擇性雙官能基的 4-isocyanato-4’ (3,3-dimethyl-2,4 -dioxoazetidino)diphenylmethane(IDD)做為構築單元,再分別與具羥基和氨基等活性氫官能基的化合物進行反應,在溫和條件、無催化劑與高產率精準合成出具有兩種不同化學反應性之規則樹枝狀高分子。透過反應優化與設計,並成功免除了傳統樹枝 狀高分子保護/去保護,或是活化/去活化等等繁瑣之合成方法,成功合成出外圍含 溴官能基與核心為aztidine-2,4-dione 官能基的之雙官能基poly(urea/maloamide)s 樹 枝狀高分子。此外,由於光化學受體 dipicolylamine 之二級胺和 aztidine-2,4-dione之間具有反應性,透過測試反應優化實驗條件後,成功以一鍋化合成方法對溴官能 基進行取代反應而不產生 aztidine-2,4-dione 官能基的開環加成反應,在 1.5 代的雙官能基 poly(urea/maloamide)s 樹枝狀高分子上能夠展現出將近 100%的反應選擇性。以上述反應為基礎,一系列具多個化學感受器的 poly(urea/maloamide)s 樹枝狀高分 子能夠合成出來,並應用於光化學感測器應用。 | zh_TW |
dc.description.abstract | A series of dentritic poly(urea/malonamide)s functionalized with chemoreceptors were prepared through an efficient iterative synthesis for fluorescent sensors. The dendrons were first prepared from the dual functional building block 4-isocyanato-4’ (3,3-dimethyl-2,4 -dioxoazetidino)diphenylmethane (IDD) as the starting materials. Throught, the use of IDD and active hydrogene such as hydroxyl and amino group, a series of well-defined bifunctional poly(urea/maloamide)s dendrons with peripheral bromo moieties were realized under mild condition without resorting to painstaking protection-deprotection or activation methodology. In the model study between dipicolylamine and aztidine-2,4-dione, the results revealed the chemical activity of the secondary amine for dipicolylamine, leading to an unusual synthetic strategy to achieve the dendritc chemoreceptors. Consequently, these chemoreceptors-functionalized dendrons would be able to exhibit specific metal ion affinity for applications of fluorescent sensors. | en |
dc.description.provenance | Made available in DSpace on 2021-06-17T07:37:10Z (GMT). No. of bitstreams: 1 ntu-108-R05524096-1.pdf: 5292135 bytes, checksum: d4b1b2221f987cd43fa7f9e35fcbdc62 (MD5) Previous issue date: 2019 | en |
dc.description.tableofcontents | TABLE OF CONTENTS
ACKNOLEDGEMENTS......i 摘要......ii ABSTRACT......iii TABLE OF CONTENTS......iv LIST OF FIGURES......vii LIST OF TABLES......x LIST OF SCHEMES......i Chapter I INTRODUCTION......1 1.1 Dendrimer......1 1.2 Synthesis method of dendrimer......4 1.3 Poly(urea/malonamide) dendrons......6 1.4 Application for dendrimer......9 1.5 Supramolecular materials......11 1.6 Photoluminescence for chemical sensor......17 Chapter II EXPERIMENT......20 2.1 Experimental materials and solvent......20 2.2 Experimental method......24 2.3 Experimental flow chart......26 2.4 Synthetic scheme......27 2.4.1 Post – functionalization derivatives......27 2.4.2 Attachment of DPA moiety......28 2.5 Synthesis of building block ......29 2.6 The series of poly(urea/malonamide) dendrons ......31 2.6.1 Synthesis of IDD......31 2.6.2 Synthesis of G0.5 - C11 – Br......32 2.6.3 Synthesis of G1.0 - C11 – Br......33 2.6.4 Synthesis of G1.5 - C11 - Br......34 2.6.5 Synthesis of G2.0 - C11 – Br......35 2.6.6 Synthesis of G2.5 - C11 – Br......36 2.7 Method of one-pot synthesis......38 2.8 The series of poly(urea/malonamide) dendrons with DPA......41 2.8.1 Synthesis of C4 - G0.5 - C11 - DPA......41 2.8.2 Synthesis of C4 - G1.5 - C11 - DPA......42 2.8.3 Synthesis of C4 - G2.5 - C11 – DPA......43 Chapter III RESULTS AND DISCUSSIONS......44 3.1 IDD 4-isocyanato-4’ (3,3-dimethyl-2,4 -dioxo-azetidino)diphenylmethane......44 3.2 The series of poly(urea/malonamide) dendrons......46 3.2.1 Identification of IDD......46 3.2.2 Identification of G0.5 - C11 – Br......47 3.2.3 Identification of G1.0 - C11 – Br......47 3.2.4 Identification of G1.5 - C11 – Br......48 3.2.5 Identification of G2.0 - C11 – Br......48 3.2.6 Identification of G2.5 - C11 – Br......49 3.3 Selective reactivity study......58 3.3.1 Primary amine reaction......58 3.3.2 Secondary amine reaction......61 3.4 The series of poly(urea/malonamide) dendrons with DPA......63 3.4.1 Identification of C4 - G0.5 - DPA......63 3.4.2 Identification of C4 - G1.5 - DPA......63 3.4.3 Identification of C4 - G2.5 - DPA......64 3.5 Thermal properties of the series of dendrons......69 3.6 Optical properties of the series of dendrons......72 3.7 Supporting information......75 Chapter IV CONCLUSION......90 Chapter VI REFERENCES......91 | |
dc.language.iso | en | |
dc.title | 合成具有化學受體的規則樹枝狀高分子應用於螢光感測 | zh_TW |
dc.title | Synthsis of Dendritic Polymers Functionalized with Chemoreceptors for Fluorescent Sensors | en |
dc.type | Thesis | |
dc.date.schoolyear | 107-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 劉定宇,南豪,陳錦地,邱文英,吳建欣 | |
dc.subject.keyword | 樹枝狀高分子,高分子後修飾,poly(urea/maloamide)s,光化學感測, | zh_TW |
dc.subject.keyword | dendrons,post-functionalization,chemosensors, | en |
dc.relation.page | 93 | |
dc.identifier.doi | 10.6342/NTU201900683 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2019-03-28 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 高分子科學與工程學研究所 | zh_TW |
顯示於系所單位: | 高分子科學與工程學研究所 |
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