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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
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dc.contributor.advisor | 鍾孝文(Hsiao-Wen Chung) | |
dc.contributor.author | Cheng-Ping Chien | en |
dc.contributor.author | 錢政平 | zh_TW |
dc.date.accessioned | 2021-06-17T07:14:53Z | - |
dc.date.available | 2021-01-20 | |
dc.date.copyright | 2021-01-20 | |
dc.date.issued | 2020 | |
dc.date.submitted | 2021-01-06 | |
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dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/73038 | - |
dc.description.abstract | 我們利用3T磁振造影儀,比較兩種不同序列所呈現出的膽道胰管影像(MRCP),在不同位置其清晰程度差異性比較分析。所採用的兩種序列分別為gradient- and spin-echo (GRASE) 3D影像,以及thick-slab fast spin-echo (FSE) 2D影像。全部受檢測者總共為95人(男/女 = 49:46,年齡介於 25-75歲),3T磁振造影參數調校以一次呼吸閉氣的時間內能夠完成影像,且不超過組織安全可曝露能量(SAR)的上限值為原則。膽道及胰管依解剖構造分為八個區段來比較影像呈現,依是否符合臨床診斷所能接受之影像品質,採用4個等第分類。 在總膽管、總肝管區段,3D GRASE MRCP 的表現比2D FSE MRCP 來得好 (兩者p < 0.001),在右前肝內膽管(p < 0.001)、右後肝內膽管(p < 0.005) 、胰管遠段 (p < 0.05)區域,則為2D FSE MRCP比3D GRASE MRCP 的表現好。另外可以發現同時合併這兩個序列的影像一起判讀,左肝內膽管無法診斷的情形可以減少至10個受測者(5.3%),而原本3D GRASE MRCP有31個(16.3%)受測者左肝內膽管無法診斷,2D FSE MRCP有21個(11.1%)受測者左肝內膽管無法診斷。 儘管在單一次呼吸閉氣的MRCP檢查中,3D GRASE MRCP 對於總膽管及總肝管的診斷較為有利,但2D FSE MRCP在較小管徑的位置仍舊有較好的表現,兩者為互補性的關係。 | zh_TW |
dc.description.abstract | We compare the depiction conspicuity of three-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) based on gradient- and spin-echo (GRASE) and two-dimensional (2D) thick-slab MRCP using fast spin-echo (FSE) in different segments of hepatic and pancreatic ducts at 3T. There were 95 subjects (M/F = 49:46, age range = 25-75) performed for at 3T. The parameters are adjusted under the constraints of specific absorption rate and scan time within single breath-hold. Conspicuity of eight ductal segments was graded by two experienced raters using a 4-point score. 3D GRASE MRCP outperformed 2D thick-slab FSE MRCP in the common bile duct and common hepatic duct (both with p < 0.001), but compared inferiorly in the right anterior hepatic duct (p < 0.001), right posterior hepatic duct (p < 0.005) and pancreatic duct distal (p < 0.05). Performing both 3D and 2D MRCP would reduce the number of non-diagnostic readings in the left hepatic duct to 10 remaining (5.3%), compared with 31 (16.3%) or 21 (11.1%) out of 190 readings if using 3D GRASE or 2D thick-slab FSE alone, respectively. Although 3D GRASE MRCP is preferential to visualize the common bile duct and common hepatic duct within one single breath-hold, the complementary role of 2D thick-slab FSE MRCP in smaller hepatic and pancreatic ducts makes it a useful adjunct if performed additionally. | en |
dc.description.provenance | Made available in DSpace on 2021-06-17T07:14:53Z (GMT). No. of bitstreams: 1 U0001-2612202012031800.pdf: 6605958 bytes, checksum: 680ef152be34ad8fb9d569e393422331 (MD5) Previous issue date: 2020 | en |
dc.description.tableofcontents | 口試委員審定書…………………………………………………………i 誌謝………………………………………………………………………ii 中文摘要…………………………………………………………………iii Abstract…………………………………………………………………..iv Contents…………………………………………………………………..v List of figures…………………………………………………………….vii List of tables……………………………………………………………..viii Chapter 1 Introduction ………………………………………………….. 1 Chapter 2 FSE and GRASE sequences …………………………………. 4 2.1 FSE technique for MRCP ………………………………….. 4 2.2 GRASE technique …………………………………………. 7 2.3 Disadvantages of GRASE ………………………………..10 2.4 Unique advantages of GRASE ……………………………11 Chapter 3 Materials and Methods ………………………………………..14 3.1 Subjects …………………………………………………...14 3.2 Image acquisition …………………………………………15 3.3 Performance evaluation …………………………………..18 Chapter 4 Results ………………………………………………………...21 Chapter 5 Discussions and Conclusion …………………………………..29 5.1 Discussion ………………………………………………...29 5.2 Limitation …………………………………………………30 5.3 Conclusion ………………………………………………...34 Appendage ………………………………………………………………..35 Reference …………………………………………………………………38 | |
dc.language.iso | en | |
dc.title | 3T MRI單次閉氣之膽道胰管磁振造影:比較3D GRASE 及 2D FSE 成像結果 | zh_TW |
dc.title | MRCP at 3T in a single breath-hold: comparative effectiveness between 3D gradient- and spin-echo and 2D thick-slab fast spin-echo acquisitions | en |
dc.type | Thesis | |
dc.date.schoolyear | 109-1 | |
dc.description.degree | 博士 | |
dc.contributor.oralexamcommittee | 李潤川(Run-Chuan Lee),劉昌憲(Chang-Sian Liou),阮春榮(Chun-Jung Juan),黃騰毅(Teng-Yi Huang),林益如(Yi-Ru Lin) | |
dc.subject.keyword | 2D厚片取樣,3D影像,單一次閉氣,梯度及自旋回聲,磁振膽道胰管造影, | zh_TW |
dc.subject.keyword | 2D thick-slab acquisition,3D imaging,breath-hold,gradient- and spin-echo,MR cholangiopancreatography, | en |
dc.relation.page | 43 | |
dc.identifier.doi | 10.6342/NTU202004465 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2021-01-06 | |
dc.contributor.author-college | 電機資訊學院 | zh_TW |
dc.contributor.author-dept | 生醫電子與資訊學研究所 | zh_TW |
顯示於系所單位: | 生醫電子與資訊學研究所 |
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