壓阻式感測器與脈波傳播速率量測用於研發非侵入式即時血流監測系統

Abstract

本研究提出一種可攜式、即時且易於操作之急救用血流狀態監測裝置，可即時監測病患的動脈內血壓與血流速度。針對心臟驟停的患者施予心肺復甦術的過程中，需要以手指碰觸患者的頸動脈以探測脈搏，方能確認其恢復狀況。然而此方法缺乏量化之標準，需要依靠專業醫護人員的經驗，並且時常發生誤判的情況。因此，本研究根據人體血液循環系統的特性，利用光體積變化掃描器與自行設計的壓阻式脈波感測器，並設計後端電路與演算法以擷取、分析脈搏波型，整合為可量測手部與頸部動脈之脈波傳播速率的裝置。本研究利用此裝置量測受試者之血壓與血液流速，並分析其與脈波傳播速率的關係且建立其理論模型。本論文提出一套非侵入式血流狀態探測系統，期未來能整合於現行的急救裝置中。

In this thesis, we proposed a real-time blood-flow-monitoring system with the merits of being portable and easy-to-operate for medical emergency applications. This device was designed to measure the patients’ blood pressures and arterial blood flow velocities via a non-invasive measuring approach. In most circumstances of performing cardiopulmonary resuscitation (CPR) to cardiac arrest patients, rescuers are required to palpate the patients’ carotid arteries to detect the recovery status. However, this method is unreliable due to the lack of quantitative standards and frequent misjudgments. Therefore, based on the characteristics of human blood circulation system, we adopt photoplethysmogram (PPG) sensors, a new design of piezoresistive arterial pulse sensors (APS), the signal processing circuits, and heartbeat waveform analyzing algorithms. By integrating these technics, we proposed a device that measured peripheral pulse wave velocities (PWV) at hands and necks of humans. We furthermore measured blood pressures and blood flow velocities from different subjects and analyzed the relations. In conclusion, we presented a non-invasive real-time blood-flow-monitoring system and it is expected to be integrated with the current emergency devices for practical medial resuscitations.