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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 邱勝賢(Sheng-Hsien Chiu) | |
| dc.contributor.author | Shun-Te Tung | en |
| dc.contributor.author | 董順德 | zh_TW |
| dc.date.accessioned | 2021-06-17T02:16:25Z | - |
| dc.date.available | 2023-01-04 | |
| dc.date.copyright | 2018-01-04 | |
| dc.date.issued | 2017 | |
| dc.date.submitted | 2017-09-29 | |
| dc.identifier.citation | 1. J.-M. Lehn, Science 1993, 260, 1762–1763.
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Soc. 1986, 108, 6250–6254. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/68277 | - |
| dc.description.abstract | 第一部分：以鈉離子導引兩條二乙二醇鏈正交排列並合成[2]交環烷
如欲有效率地建構[2]交環烷，常藉由模板導引法將分子個別的前驅物元件適當排列，然而並沒有任何以鹼金屬離子為模板的先例。在本文中，我們報導了以五個元件 (兩個二醛分子、兩個二胺分子、一個鈉離子) 自組裝合成[2]交環烷。這種簡單而有效的合成策略能將鈉離子作為模板，使含有二乙二醇鏈的二胺分子兩兩正交排列，並與二醛分子反應生成[2]交環烷。利用硼氫化鈉還原不穩定的亞胺鍵，以分離並鑑定穩定的[2]交環烷。 第二部分：環狀[2]交環烷二聚體之合成研究 先前我們報導了以鈉離子為模板，使含有二乙二醇鏈的二胺分子兩兩正交排列，並與二醛分子反應生成[2]交環烷。於此，我們希望能延伸此系統，設計具有特定角度的四醛分子，搭配二胺分子與鈉離子模板，以動態亞胺鍵一鍋化自組裝成環狀[2]交環烷寡聚體。利用硼氫化鈉還原不穩定的亞胺鍵，並甲基化所得的二級胺，以分離並鑑定由共價鍵建構且穩定的環狀[2]交環烷二聚體。 | zh_TW |
| dc.description.abstract | Part I : Synthesis of a [2]Catenane from the Sodium Ion Templated Orthogonal Arrangement of Two Diethylene Glycol.
An important feature for the efficient construction of a [2]catenane is the appropriate alignment of the individual precursor molecular components by template-directed synthesis. However, we were unaware of any examples of the use of alkali metal ions as a template. Herein, we report the synthesis of a [2]catenane from five components (two diamines, two dialdehydes, one Na+ ion). This simple and efficient synthesis strategy makes use of a Na+ ion as a template to align two di(ethylene glycol)-containing diamines in an orthogonal manner, which can then react with two units of dialdehyde to generate [2]catenanes. NaBH4 mediated reduction of the labile imino bonds enabled the isolation and characterization of the [2]catenane as a stable compound. Part II : Synthesis of a Cyclic [2]Catenane Dimer. Previously, we reported that Na+ ions can template the orthogonal alignment of two di(ethylene glycol)-containing diamines, which can then react with two units of dialdehyde to generate [2]catenanes. We wished to extend this concept by applying the tetraaldehyde with specific angle for the corresponding reaction with diamine and Na+ ions to dynamically synthesis cyclic [2]catenane oligomers. NaBH4 mediated reduction of the labile imino bonds of these cyclic [2]catenane oligomers, followed by methylation of the resulting secondary amino groups enabled the isolation and characterization of a dimeric cyclic [2]catenane as stable, covalently linked compounds. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-17T02:16:25Z (GMT). No. of bitstreams: 1 ntu-106-D01223137-1.pdf: 6584059 bytes, checksum: 9561707a793bea364aecc436ee101477 (MD5) Previous issue date: 2017 | en |
| dc.description.tableofcontents | 口試委員會審定...........................................I
中文摘要...............................................II 英文摘要...............................................III 論文發表................................................V 目錄..................................................VII 圖目錄.................................................IX 流程目錄...............................................XI 表目錄................................................XII 第一章、緒論.............................................1 1.1 超分子化學簡介...................................1 1.2 主客化學與冠醚分.................................2 1.3 交環烷分子 (catenane) 簡介.......................4 1.4 早期交環烷的合成.................................5 1.5 以模板導引法合成交環烷............................6 第二章、以鈉離子導引兩條二乙二醇鏈正交排列並合成[2]交環烷...12 2.1 研究動機........................................13 2.2 實驗結果與討論..................................14 2.3 結論...........................................20 第三章、環狀[2]交環烷二聚體之合成研究.....................21 3.1 研究動機........................................22 3.2 60度四醛分子 7 之合成...........................24 3.3 實驗結果與討論..................................25 3.4 結論...........................................30 第四章、實驗部分........................................31 第五章、參考資料........................................37 第六章、附錄............................................42 | |
| dc.language.iso | zh-TW | |
| dc.subject | 交環烷 | zh_TW |
| dc.subject | 鈉離子模板 | zh_TW |
| dc.subject | 自組裝 | zh_TW |
| dc.subject | catenane | en |
| dc.subject | sodium Ion templated | en |
| dc.subject | self-assembly | en |
| dc.title | 以鈉離子導引兩條二乙二醇鏈正交排列並合成[2]交環烷 | zh_TW |
| dc.title | Synthesis of a [2]Catenane from the Sodium Ion Templated Orthogonal Arrangement of Two Diethylene Glycol | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 106-1 | |
| dc.description.degree | 博士 | |
| dc.contributor.oralexamcommittee | 陳平(Richard P. Cheng),徐秀福(Hsiu-Fu Hsu),李文山(Wen-Shan Li),賴建成(Chien-Chen Lai) | |
| dc.subject.keyword | 交環烷,鈉離子模板,自組裝, | zh_TW |
| dc.subject.keyword | catenane,sodium Ion templated,self-assembly, | en |
| dc.relation.page | 56 | |
| dc.identifier.doi | 10.6342/NTU201704228 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2017-09-29 | |
| dc.contributor.author-college | 理學院 | zh_TW |
| dc.contributor.author-dept | 化學研究所 | zh_TW |
| 顯示於系所單位： | 化學系 | |
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