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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 鍾孝文(Hsiao-Wen Chung) | |
dc.contributor.author | Yi-Ying Wu | en |
dc.contributor.author | 吳宜螢 | zh_TW |
dc.date.accessioned | 2021-06-17T00:21:55Z | - |
dc.date.available | 2012-06-29 | |
dc.date.copyright | 2012-06-29 | |
dc.date.issued | 2012 | |
dc.date.submitted | 2012-06-14 | |
dc.identifier.citation | References
1. Lisa Hill, C.G., cerebral blood flow and intracranial pressure. Originally published in Anaesthesia Tutorial of the Week, 2007: p. 30-35. 2. Morgan, R.R.a.R.J., Intracranial pressure monitoring. Current Anaesthesia & Critical Care, 2003. 14: p. 229-235. 3. Hamilton, W.F., Intracranial Pressure. Can Med Assoc J, 1918. 8(10): p. 873-81. 4. Dunn, L.T., Raised intracranial pressure. J Neurol Neurosurg Psychiatry, 2002. 73 Suppl 1: p. i23-7. 5. Marmarou, A., K. Shulman, and J. LaMorgese, Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system. J Neurosurg, 1975. 43(5): p. 523-34. 6. Raksin, P.B., et al., Noninvasive intracranial compliance and pressure based on dynamic magnetic resonance imaging of blood flow and cerebrospinal fluid flow: review of principles, implementation, and other noninvasive approaches. Neurosurg Focus, 2003. 14(4): p. e4. 7. Alperin, N.J., et al., MR-Intracranial pressure (ICP): a method to measure intracranial elastance and pressure noninvasively by means of MR imaging: baboon and human study. Radiology, 2000. 217(3): p. 877-85. 8. Alperin, N., et al., Analysis of magnetic resonance imaging-based blood and cerebrospinal fluid flow measurements in patients with Chiari I malformation: a system approach. Neurosurg Focus, 2001. 11(1): p. E6. 9. North, B., intracranial pressure monitoring. 1997. 10. Wagshul, M.E., P.K. Eide, and J.R. Madsen, The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility. Fluids Barriers CNS, 2011. 8(1): p. 5. 11. Ellenby, M.S., et al., Videos in clinical medicine. Lumbar puncture. N Engl J Med, 2006. 355(13): p. e12. 12. Baral, B., Intracranial pressure monitoring: concepts in evaluation and measurement. Pak J Med Sci, 2007. 23: p. 798-804. 13. Tain, R.W. and N. Alperin, Noninvasive intracranial compliance from MRI-based measurements of transcranial blood and CSF flows: indirect versus direct approach. IEEE Trans Biomed Eng, 2009. 56(3): p. 544-51. 14. F., M., Recherches physiologiques et cliniques sur le liquide cephalorachidien ou cerebro-spinal. 1842. 15. Tain, R.W., B. Ertl-Wagner, and N. Alperin, Influence of the compliance of the neck arteries and veins on the measurement of intracranial volume change by phase-contrast MRI. J Magn Reson Imaging, 2009. 30(4): p. 878-83. 16. Ueno, T., et al., Development of a noninvasive technique for the measurement of intracranial pressure. Biol Sci Space, 1998. 12(3): p. 270-1. 17. Urchuk, S.N. and D.B. Plewes, MR measurements of pulsatile pressure gradients. J Magn Reson Imaging, 1994. 4(6): p. 829-36. 18. Alperin, N., MR measurements of intracraniospinal CSF pulsatile pressure gradients (abstr.). Proceedings of the fourth meeting of the International Society for Magnetic Resonance in Medicine., 1996. 19. Loth, F., M.A. Yardimci, and N. Alperin, Hydrodynamic modeling of cerebrospinal fluid motion within the spinal cavity. J Biomech Eng, 2001. 123(1): p. 71-9. 20. H, S., Boundary layer theory. 1979: p. 47-69. 21. Rosner, M.J. and I.B. Coley, Cerebral perfusion pressure, intracranial pressure, and head elevation. J Neurosurg, 1986. 65(5): p. 636-41. 22. Alperin, N., et al., Quantifying the effect of posture on intracranial physiology in humans by MRI flow studies. J Magn Reson Imaging, 2005. 22(5): p. 591-6. 23. Alperin, N., A. Sivaramakrishnan, and T. Lichtor, Magnetic resonance imaging-based measurements of cerebrospinal fluid and blood flow as indicators of intracranial compliance in patients with Chiari malformation. J Neurosurg, 2005. 103(1): p. 46-52. 24. Troupp, H., Intracranial pressure in hydrocephalus after subarachnoid haemorrhage. Zentralbl Neurochir, 1975. 36(1): p. 11-7. 25. Sklar, F.H. and I. Elashvili, The pressure-volume function of brain elasticity. Physiological considerations and clinical applications. J Neurosurg, 1977. 47(5): p. 670-9. 26. Szewczykowski, J., et al., A fast method of estimating the elastance of the intracranial system. J Neurosurg, 1977. 47(1): p. 19-26. 27. BR., N., Cerebrospinal fluid and intracranial pressure. Textbook of clinical neurology., 1999: p. 475-490. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/66104 | - |
dc.description.abstract | 目前在臨床上用於量測人體顱內壓技術是一種相當高侵入性的技術。利用從體外放入壓力偵測探頭至中樞神經系統(側腦室或腰椎)來觀測人體的顱內壓變化量。但是,在進行此高侵入性方法的診斷或治療時,往往病人會伴隨著感染或是引發其他併發症。這樣高風險的侵入式技術並非每位受檢者都有辦法承受,因此,我們想要發展出一套由相位對比磁共振影像為基礎出發的非侵入性顱內壓檢測技術。
先前的研究已經提出利用動態相位對比磁共振影像來估測顱內壓以及其相關參數。在這個研究中,我們想要重複這個數年前就已被廣泛接受的方法,並且更進一步地去探討這個方法在正常受試者身上的可重複性以及精確性,除此之外,還原先前研究的一些簡化與假設,讓此相位對比磁共振影像用於非侵入性地量測人體顱內壓的技術更健全完善以便提供更清楚的臨床意義。 | zh_TW |
dc.description.abstract | Currently the ICP measurement method performed in clinical practice is a highly invasive technique. An external pressure detector has to be placed in the central nervous system such as lateral ventricle or lumbar spine for monitoring the pressure changes. However, the continuous ICP monitoring is usually accompanied by risks including possible infections. In addition, in the surgical procedure may impose potential morbidity for the patients. These considerations drive investigators to develop noninvasive techniques for ICP estimation.
Previous studies have proposed noninvasive cine phase-contrast MRI method to estimate the ICP and its related indices, ICC and ICE, based on blood / CSF volumetric flow rates and CSF pressure gradient. In this study, we attempted to repeat this accepted measurement method to assess its precision level on healthy subjects, and at the same time verify the validity of some simplified assumptions practically in order to get more comprehensive estimation as well as provide clearer clinical significance. | en |
dc.description.provenance | Made available in DSpace on 2021-06-17T00:21:55Z (GMT). No. of bitstreams: 1 ntu-101-R99945016-1.pdf: 1678738 bytes, checksum: a0c2f01e8bba9abcf668a2c434656f9a (MD5) Previous issue date: 2012 | en |
dc.description.tableofcontents | CONTENTS
口試委員會審定書 ............................................................................................................i 致謝 .................................................................................................................................. ii 中文摘要 ......................................................................................................................... iii 英文摘要 ..........................................................................................................................iv Chapter 1 Introduction .............................................................................................. 1 1.1 Intracranial pressure (ICP), intracranial compliance (ICC), and intracranial elastance (ICE)................................................................................................ 1 1.2 Current methods for ICP measurement .......................................................... 4 1.3 Imaging based methods for ICP measurement ............................................... 5 Chapter 2 Materials and Methods .......................................................................... 11 2.1 Subjects ......................................................................................................... 11 2.2 Data acquisition ............................................................................................ 11 2.3 Measurement of intracranial volume change ................................................ 13 2.4 Measurement of intracranial pressure gradient change ................................ 16 2.5 The effect of posture on intracranial physiology .......................................... 19 2.6 Reproducibility of intracranial volume changes, pressure gradient changes, and elastance index measurements ............................................................... 21 2.7 Statistical testing ........................................................................................... 21 Chapter 3 Results ..................................................................................................... 35 3.1 Experiment 1:Medium pillow (MP) examination ...................................... 35 3.2 Experiment 2:Low pillow (LP) and high pillow (HP) pair examination ... 36 3.3 Reproducibility ............................................................................................. 37 3.4 MR imaging-derived ICP value .................................................................... 38 Chapter 4 Discussion and Conclusion .................................................................... 45 4.1 Measurements of intracranial volume change .............................................. 46 4.2 Measurements of intracranial pressure gradient changes ............................. 46 4.3 The effect of pillow height on intracranial physiology ................................ 49 4.4 Reproducibility ............................................................................................. 51 REFERENCE .................................................................................................................. 53 | |
dc.language.iso | zh-TW | |
dc.title | 磁振造影顱內壓量測的重現性與切面內腦脊髓液流速的影響 | zh_TW |
dc.title | MR imaging-based intracranial pressure estimation: reproducibility and contributions of in-plane CSF flow. | en |
dc.type | Thesis | |
dc.date.schoolyear | 100-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 蔡芳洋(Fong Y. Tsai),蔡志文(Jyh-Wen Chai),黃騰毅(Teng-Yi Huang),彭旭霞(Hsu-Hsia Peng) | |
dc.subject.keyword | 相位對比磁共振影像,非侵入性顱內壓量測,顱內彈性係數,腦脊髓液,流體力學, | zh_TW |
dc.subject.keyword | MR-intracranial pressure,intracranial compliance,intracranial elastance,cerebrospinal fluid dynamic,phase contrast magnetic resonance imaging, | en |
dc.relation.page | 55 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2012-06-15 | |
dc.contributor.author-college | 電機資訊學院 | zh_TW |
dc.contributor.author-dept | 生醫電子與資訊學研究所 | zh_TW |
顯示於系所單位: | 生醫電子與資訊學研究所 |
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