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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 劉?睿 | |
dc.contributor.author | Chia-Hui Ho | en |
dc.contributor.author | 何佳慧 | zh_TW |
dc.date.accessioned | 2021-06-16T17:16:11Z | - |
dc.date.available | 2014-08-20 | |
dc.date.copyright | 2012-08-20 | |
dc.date.issued | 2012 | |
dc.date.submitted | 2012-08-18 | |
dc.identifier.citation | 李庭羽。2011。益生菌 Bacillus licheniformis CK1 於腸道免疫反應之研究。碩士論文。國立臺灣大學動物科技學系。
林家民。2007。精芻料比例調整與飼糧微生物添加對臺灣長鬃山羊採食及糞便型態之影響。碩士論文。國立臺灣大學動物科技學系。 Alexopoulos, C., I. E. Georgoulakis, A. Tzivara, C. S. Kyriakis, A. Govaris, and S. C. Kyriakis. 2004. Field evaluation of the effect of a probiotic containing Bacillus licheniformis and Bacillus subtilis spores on the health status, performance, and carcass quality of grower and finisher pigs. J. Vet. Med. A Physiol. Pathol. Clin Med. 51:306–312. Allan, G. G., J. R. Fox, G. D. Crosby, and K. V. Sarkanen. 1977. Chitosan, a mediator for fiber-water interactions in paper. Seattle: College of Forest Resources, University of Washington Press. AOAC. 1990. Official Methods of Analysis. 15th ed. Assoc. Offic. Anal. Chem., Arlington, VA. Aviagen incorporated. 2009. Arbor Acres plus broiler nutrition specification. Huntsville, AL. Boirivant, M., and W. Strober. 2007. The mechanism of action of probiotics. Curr. Opin. Gastroenterol. 23: 679–692. Buyse, J., G. P. J. Janssens, and E. Decuypere .2001. The effects of dietary L-carnitine supplementation on the performance, organ weights and circulating hormone and metabolite concentrations of broiler chickens reared under a normal or low temperature schedule. Br. Poult. Sci. 42:230-241. Cabezas, J. A. 1989. Some comments on the type references of the official nomenclature (IUB) for b-N-acetylglucosaminidase, b-N-acetylhexosaminidase and b-N-acetylgalactosaminidase. Biochem. J. 261:1059-1060. Chen, Y. J., I. H. Kim, J. H. Cho, J. S. Yoo, Y. Wang, Y. Huang, H. J. Kim, and S. O. Shin. 2009. Effects of chitooligosaccharide supplementation on growth performance, nutrient digestibility, blood characteristics and immune responses after lipopolysaccharide challenge in weanling pigs. Livest. Sci. 124:255-260. Chiang, M. T., H. T. Yao, and H. C. Chen. 2000. Effect of dietary chitosans with different viscosity on plasma lipids and lipid peroxidation in rats fed on a diet enriched with cholesterol. Biosci. Biotechnol. Biochem. 5:965–971. Claus, D., and R. C. W. Berkeley. 1986. Genus Bacillus Cohn 1872. Page 1105-1139 in Bergey’s Manual of Systematic Bacteriology. P. H. A. Sneath, ed. Williams & Wilkins Co. Baltimore, MD. Cody,R.M. 1989. Ditribution of chitinase and chitobiase in Bacillus. Curr. Microbiol.19:201-205. Dahiya, N., R. Tewari, and G. S. Hoondal. 2006. Biotechnological aspects of chitinolytic enzymes: a review. Appl. Microbiol. Biotechnol. 71: 773–782. Degering, C., T. Eggert, M. Puls, J. Bongaerts, S. Evers, K. H. Maurer, and K. E. Jaeger. 2010. Optimization of Protease Secretion in Bacillus subtilis and Bacillus licheniformis by Screening of Homologous and Heterologous Signal Peptides. Appl. Environ. Microbiol. 76:6370-6376. Deng, X., X. Li, P. Liu, S. Yuan, J. Zang, S. Li, and X. Piao. 2008. Effects of chito-oligosaccharide supplementation on immunity in broiler chickens. Asian-Aust. J. Anim. Sci. 21:1651-1658. De Vrese M, Schrezenmeir J. 2008. Probiotics, prebiotics, synbiotics. Adv. Biochem. Eng. Biotechnol. 111: 1–66. Duc, H., H. A. Hong, and S. M. Cutting. 2003. Germination of the spore in the gastrointestinal tract provides a novel route for heterologous antigen delivery. Vaccine. 21:4215–4224. Duc, H., H. A. Hong, T. M. Barbosa, A. O. Henriques, and S. M. Cutting. 2004. Characterization of Bacillus probiotics available for human use. Appl. Environ. Microbiol. 70:2161-2171. FAO/WHO. 2002. Joint FAO/WHO (Food and Agriculture Organization/World Health Organization) working group report on drafting guidelines for the evaluation of probiotics in food. London, Ontario, Canada. Feng, J., L. Zhao, and Q. Yu. 2004. Receptor-mediated stimulatory effect of oligochitosan in macrophages. Biochem. Biophys. Res. Commun. 317:414–420. Fiorini, G., C. Cimminiello, R. Chianese, G. P. Visconti, D. Cova, T. Uberti, and A. Gibelli. 1985. Bacillus subtilis selectively stimulates the synthesis of membrane bound and secreted IgA. Chemiotherapia. 4:310–312. Fischer, E.H, and E. A. Stein. 1960. Cleavage of O- and S-glycosidic bonds survey. Page301-312 in The Enzymes. 2nd ed. P. D. Boyer, H. Lardy, and K Myrback, ed. Academic Press, New York, NY. Fuller, R. 1989. Probiotics in man and animals. J. Appl. Bacteriol. 66:365–378. Gao, X. A., W. T. Ju, W. J. Jung, and R. D. Park. 2008. Purification and characterization of chitosanase from Bacillus cereus D-11. Carbohydr Polym. 72:513–520. Goldsby, R. A., T. J. Kindt, B. A. Osborne, J. Kuby. 2000. Kuby immunology. 4th ed. Page 338 in Leukocyte Migration and Inflammation. W.H. Freeman. New York, NY. Grenier, J., and A. Asselin. 1990. Some pathogenesis related proteins are chitosanases with lytic activity against fungal spores. Mol. Plant Microbe Interact. 3:401-407. Gross, W. B., and H. S. Siegel. 1983. Evaluation of heterophile/lymphocyte ratio as a measure of stress in chickens. Avian Dis. 27:972-979. Havenaar, R., and J. H. J. Huis in’t Veld. 1992. Probiotics: a general view. Page 209-224 in The lactic acid bacteria in health and disease. B. J. B. Wood, ed. Chapman & Hall, New York, NY. Hartemink, R., V. R. Domenech, and F. M. Rombouts. 1997. LAMVAB-A new selective medium for the isolation of Lactobacilli trom faeces. J. Microbiol. Methods 29:77-84. Hoa, T. T., L. H. Duc, R. Isticato, L. Baccigalupi, E. Ricca, P. H. Van, and S. M. Cutting. 2001. The fate and dissemination of Bacillus subtilis spores in a murine model. Appl. Environ. Microbiol. 67:3819–3823. Hoffmann, G., Daum, M. Koster, W. M. Kulicke, H. Meyer-Rammes, B. Bisping, and F. Meinhardt. 2010. Genetic improvement of Bacillus licheniformis strains for efficient deproteinization of shrimp shells and production of high-molecular-mass chitin and chitosan. Appl. Environ. Microbiol. 76:8211–8221. Huang, R. L., Z. Y. Deng, C. B. Yang, Y. L. Yin, M. Y. Xie, G. Y. Wu, T. J. Li, L. L. Li, Z. R. Tang, P. Kang, Z. P. Hou, D. Deng, H. Xiang, X. F. Kong, and Y. M. Guo. 2007. Dietary oligochitosan supplementation enhances immune status of broilers. J. Sci. Food Agric. 87:153-159. Imoto, T., and K. Yagishita. 1971. A simple activity measurement of lysozyme. Agric. Biol. Chem. 35:1154-1156. Jameela, S. R., A. Misra, A., and A. Jayakrishnan. 1994. Cross-linked chitosan microspheres as carriers for prolonged delivery of macromolecular drugs. J Biomater Sci Polym Ed. 6:621–632. Jo,Y. Y., K. J. Jo,Y. L. Jin,K. Y. Kim, J. H. Shim, Y. W. Kim, and R. D. Park. 2003. Characterization and Kinetics of 45 kDa Chitosanase from Bacillus sp. P16. Biosci. Biotechnol. Biochem. 67:1875–1882. Kanauchi, O., K. Deuchi, Y. Imasato, M. Shizukuishi, and E. Kobayashi. 1995. Mechanism for the inhibition of fat digestion by chitosan and for the synergistic effect of ascorbate. Biosci. Biotechnol. Biochem. 59:786–790. Kim, J. Y., J. K. Lee, T. S. Lee, and W. H. Park. 2003. Synthesis of chitooligosaccharide derivative with quaternary ammonium group and its antimicrobial activity against Streptococcus mutans. Int. J. Biol. Macromol. 32:23–27. Kim, M. S., M. J. Sung, S. B. Seo, S. J. Yoo, W. K. Lim, H. M. Kim. 2002. Water-soluble chitosan inhibits the production of pro inflammatory cytokine in human astrocytoma cells activated by amyloids b peptide and interleukin-1b.Neurosci. Lett. 321:105–109. Kim, S. K., and N. Rajapakse. 2005. Enzymatic production and biological activities of chitosan oligosaccharides (COS): A review. Carbohydr Polym. 62:357–368. Knap, I., B. Lund, A. B. Kehlet, C. Hofacre, and G. Mathis. 2010. Bacillus licheniformis prevents necrotic enteritis in broiler chickens. Avian Dis. 54:931-935. Knaul, J. Z., S. M. Hudson, and K. A. M. Creber. 1999. Crosslinking of chitosan fibers with dialdehydes: Proposal of a new reaction mechanism. J. Polym. Sci. B Polym. Phys. 37:1079–1094. Kyriakis, S. C., V. K. Tsiloyiannis, J. Vlemmas, ,K. Sarris, A. C. Tsinas, C. Alexopoulos, and L. Jansegers. 1999. The effect of probiotic LSP 122 on the control of post-weaning diarrhoea syndrome of piglets. Res. Vet. Sci. 67:223–228. La Ragione, R. M., G. Casula, S. M. Cutting, and S. M. Woodward. 2001. Bacillus subtilis spores competitively exclude Escherichia coli 070:K80 in poultry. Vet. Microbiol. 79(2):133–142. Lee, K. H., K. D. Jun, W. S. Kim, H .D. Paik. 2001. Partial characterization of polyfermenticin SCD, a newly identified bacteriocin of Bacillus polyfermenticus. Lett. Appl. Microbiol. 32:146–151. Lee, K. W., S. H. Lee, H. S. Lillehoj, G. X. Li, S. I. Jang, U. S. Babu, M. S. Park, D. K. Kim, E. P. Lilleoj, A. P. Neumann, T. G. Rehberger, and G. R. Siragusa. 2010. Effect of direct-feed microbials on growth performance, gut morphometry, and immune characteristics in broiler chickens. Poult. Sci. 89:203-216. Li, X. J., X. S. Piao, S. W. Kim, P. Liu, L. Wang, Y. B. Shen, S. C. Jung, and H. S. Lee. 2007. Effects of chito-oligosaccharide supplementation on performance, nutrient digestibility, and serum composition in broiler chickens. Poult. Sci. 86:1107-1114. Lin, C. W., L. J. Chen, P. L. Lee, C. I. Lee, J. C. Lin, and J. J. Chiu. 2007. The inhibition of TNF-a-induced E-selectin expression in endothelial cells via the JNK/NF-kB pathways by highly N-acetylated chitooligosaccharides. Biomaterials 28:1355-1366. Lilly, D. M., and R. H. Stillwell. 1965. Probiotics: Growth promoting factors produced by microorganisms. Science 147:747-748. Link, R., and G. Kovač. 2006. The effect of probiotic BioPlus 2B on feed efficiency and metabolic parameters in swine. Biologia. 61:783–787. Liu, P., X. S. Piao, P. A. Thacker, Z. K. Zeng, P. F. Li, D. Wang, and S. W. Kim. 2010. Chito-oligosaccharide reduces diarrhea incidence and attenuates the immune response of weaned pigs challenged with E. coli K88. J. Anim. Sci. 88:3871-3879. Liu, X., H. Yan, L. Lv, Q. Xu, C. Yin, K. Zhang, P. Wang, and J. Hu. 2012. Growth performance and meat quality of broiler chickens supplemented with Bacillus licheniformis in drinking water. Asian Aust. J. Anim. Sci. 25 : 682 – 689. Luo, J, J. R. McMullen, C. L. Sobki, L. Zhang, A. L. Dorfman, M. C. Sherwood, M. N. Logsdon, J. W. Horner, R. A. DePinho, S. Izumo, L. C. Cantley. 2005. Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy. Mol. Cell Biol. 25:9491–9502. Maezake, Y., K. Tsuji, and Y. Nakagawa. 1993. Hypocholesterolemic effect of chitosan in adult males. Biosci. Biotechnol. Biochem. 57:1439–1444. Mazza, P. 1994. The use of Bacillus subtilis as an antidiarrhoeal microorganism. Boll. Chim. Farm. 133:3–18. McFarland, J. M., and S. E. Curtis. 1989. Multiple concurient stressors in chicks effection on plasma corticosterone and heterophils to lymphocytes ratio. Poult. Sci. 68: 522-527. Metchnikoff, E. 1907. Lactic acid as inhibiting intestinal putrefaction. Page 161-183 in The prolongation of life: Optimistic studies. P. C. Mitchell, ed. Heinemann, London, UK. Mountzouris, K. C., P. Tsirtsikos, E. Kalamara, S. Nitsch, G. Schatzmayr, and K. Fegeros. 2007. Evaluation of the efficacy of a probiotic containing Lactobacillus, Bifidobacterium, enterococcus, and Pediococcus strains in promoting broiler performance and modulating cecal microflora composition and metabolic activities. Poult. Sci. 86:309-317. Murell, W. G. 1967. The biochemistry of the bacterial endospore. Adv. Microb. Physiol. 1:133-251. Muscettola, M., G. Grasso, Z. Blach–Olszewska, P. Migliaccio, C. Borghesi-Nicoletti, M .Giarratana, and V. C. Gallo. 1992. Effects of Bacillus subtilis spores on interferon production. Pharmacol. Res. 26:176–177. Nanjo, F., R. Katsumi, and K. Sakai. 1990. Purification and characterisation of exo-b-D-glucosaminidase, a novel type of enzyme, from Nocardia orientalis. J. Biol. Chem. 265:10088-10094. Ng, S. C., A. L. Hart, M.A. Kamm, A. J. Stagg, and S. C. Knight. 2009. Mechanisms of action of probiotics: recent advances. Inflamm. Bowel Dis. 15: 300–310. Niu, D., Z. Zuo, G. Y. Sh, and Z. X. Wang. 2009. High yield recombinant thermostable α-amylase production using an improved Bacillus licheniformis system. Microb. Cell Fact. 8:58. Ohland, C., and W. Macnaughton. 2010. Probiotic bacteria and intestinal epithelial barrier function. Am. J. Physiol. Gastrointest. Liver physiol. 298:807-819. Ohtakara, A., M. Izume, and M. Mitsutomi. 1988. Action of microbial chitinases on chitosan with differentdegrees of deacetylation. Agric. Biol. Chem. 52:3181-3182. Okamoto, Y., A. Inoue, K. Miyatake, K. Ogihara, Y. Shigemasa, Y., and S. Minami. 2003. Effects of chitin/chitosan and their oligomers/monomers on migrations of macrophages. Macromol Biosci. 3:587–590. Osswald, W. F., J. P. Shapiro, R. E. McDonald, R. P. Niedz, and R. T. Mayer .1993. Some citrus chitinases alsopossess chitosanase activities. Experientia, 49:888-892. Park, J. K., K. Morita, I. Fukumoto, Y. Yamasaki, T. Nakagawa, M. Kawamukai, and H. Matsuda. 1997. Purification and characterization of the Chitinase (ChiA) from Enterobacter sp. G-1. Biosci. Biotechnol. Biochem. 61:684–689. Patel, A. K., M. K. Deshattiwar, B. L. Chaudhari, and S. B. Chincholkar. 2009. Production, purification and chemical characterization of the catecholate siderophore from potent probiotic strains of Bacillus spp. Bioresour. Technol. 100:368-373. Peniston, Q. P., and E. Johnson . 1980. Process for the manufacture of chitosan. US Patent. No. 4,195,175:5–15. Petillo, G., O. Petillo, M. Ranieri, M. Santin, L. Ambrosio, D. Calabro, B. Avallone, and G. Balsamo. 1994. Chitosan-mediated stimulation of macrophage function. Biomaterials. 15:1215–1220. Pinchuk, I. V., P. Bressollier, B. Verneuil, B. Fenet, I. B. Sorokulova, F. Megraud, and M. C. Urdaci. 2001. In vitro anti-Helicobacter pylori activity of the probiotic strain Bacillus subtilis 3 is due to secretion of antibiotics. Antimicrob. Agents Chemother. 45:3156–3161. Sahai, A. S., and M. S. Manocha.1993. Chitinases of fungi and plants: their involvement in morphogenesis and host parasite interaction. FEMS Microbiol. Rev. 11:317–338. Salminen, S., A. von Wright, L. Morelli, P. Marteau, D. Brassart, W. M. de Vos, R. Fonden, M. Saxelin, K. Collins, G. Mogensen, S. E. Birkeland, and T. Mattila-Sandholm. 1998. Demonstration of safety of probiotics-a review. Int. J. Food Microbiol. 44: 93–106. Schallmey, M., A. Singh, and O. P. Ward. 2004. Developments in the use of Bacillus species for industrial production. Can. J. Microbiol. 50:1–17. Seo, W.G., H. O. Pae, N. Y. Kim, G. S. Oh, I. S. Park, Y. H. Kim, Y. M. Kim, Y. H. Lee, C. D. Jun, and H. T. Chung. 2000. Synergistic cooperation between water-soluble chitosan oligomers and interferon-gamma for induction of nitric oxide synthesis and tumoricidal activity in murine peritoneal macrophages. Cancer Lett. 159:189–195. Setlow, P. 2006. Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals. J. Appl. Microbiol. 101:514-525. Shibata, Y., W. J. Metzger, and Q. N. Myrvik. 1997. Chitin particleinduced cell-mediated immunity is inhibited by soluble mannan: Mannose receptor-mediated phagocytosis initiates IL-12 production. J. Immunol. 18:947–951. Somashekar, D., and R. Joseph. 1996. Chitosanases propertiesandapplications:a review. Bioresour. Technol. 55:35-45. Stoll, B., D. G. Burrin, J. Henry, H. Yu, F. Jahoor, and P. J. Reeds. 1998. Dietary amino acids are the preferential source of hepatic protein synthesis in piglets. J. Nutr. 128:1517–1524. Sudharshan, N. R., D. G. Hoover, and D. Knorr. 1992. Antibacterial action of chitosan. Food Biotechnol. 6:257–272. Sugano, M., S. Watanabe, A. Kishi, M. Izume, and A. Ohtakara. 1988. Hypocholesterolemic action of chitosans with different viscosity in rats. Lipids 23:187–191. Taheri, H. R., H. Moravej, A. Malakzadegan, F. Tabandeh, M. Zaghari, M. Shivazad, and M. Adibmoradi. 2010. Efficacy of Pediococcus acidlactici-based probiotic on intestinal Coliforms and villus height, serum cholesterol level and performance of broiler chickens. Afr. J. Biotechnol. 9:7564-7567. Timmerman, H. M., A. Veldman, E. van den Elsen, F. M. Rombouts, and A. C. Beynen. 2006. Mortality and growth performance of broilers given drinking water supplemented with chicken-specific probiotics. Poult. Sci. 85:1383-1388. Tokoro, A., N. Tatewaki, K. Suzuki, T. Mikami, S. Suzuki, and M. Suzuki. 1998. Growth inhibitory effect of hexa-N-acetylchitohexaose and chitohexaos and Meth-A solid tumor. Chem. Pharm. Bull. 36:784–790. Tortuero, F. 1973. Influence of the implantation of Lactobacillus acidophilus in chicks on the growth, feed conversion, malabsorption of fats syndrome and intestinal flora. Poult. Sci. 52:197-203. Urdaci, M. C., P. Bressollier, and I. Pinchuk. 2004. Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities. J. Clin. Gastroenterol. 38:86-90. Van Immerseel, F., J. De Buck, F. Pasmans, G. Huyghebaert, F. Haesebrouck, and R. Ducatelle.2004. Clostridium perfringens in poultry: an emerging threat for animal and public health. Avian Pathol. 33:537–549. Vaseeharan, B., and P. Ramasamy. 2003. Control of pathogenic Vibrio spp. by Bacillus subtilis BT23, a possible probiotic treatment for black tiger shrimp Penaeus monodon. Lett. Appl. Microbiol. 36:83–87. Veith, B., C. Herzberg, S. Steckel, J. Feesche, K. H. Maurer, P. Ehrenreich, S. Bumer, A. Henne, H. Liesegang, R. Merkl, A. Ehrenreich, and G. Gottschalk. 2004. The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential. J. Mol. Microbiol. Biotechnol. 7:204–211. Waldeck, J., G. Daum, B. Bisping, and F. Meinhardt. 2006. Isolation and molecular characterization of chitinase-deficient Bacillus licheniformis strains capable of deproteinization of shrimp shell waste to obtain highly viscous chitin. Appl. Environ. Microbiol. 72:7879–7885. Wang, X. W., Y. G. Du, X. F. Bai, and S. G. Li. 2003. The effect of oligochitosan on broiler gut flora, microvilli density, immune function and growth performance. Acta. Zoonutr. Sin. 15:32–45. Wang, S. L., S. J. Chena, and C. L. Wang. 2008. Purification and characterization of chitinases and chitosanasesfrom a new species strain Pseudomonas sp. TKU015 using shrimp shells as a substrate. Carbohydr. Res. 343:1171–1179. Wang, S. L., W. H. Hsu, and T. W. Liang. 2010. Conversion of squid pen by Pseudomonas aeruginosa K187 fermentation for the production of N-acetyl chitooligosaccharides and biofertilizers. Carbohydr. Res. 345:880–885. Willey, J. M., L. M. Sherwood, and C. J. Woolverton. 2008. Prescott, Harley, and Klein's microbiology. 7th ed. Page 578 in Bacteria: the low G + C gram positives. McGraw-Hill Higher Education. Boston, NY. Williams, R. B. 2005. Intercurrent coccidiosis and necrotic enteritis of chickens: rational, integrated disease management by maintenance of gut integrity. Avian Pathol. 34:159–180. Williams, N. T. 2010. Probiotics. Am J Health Syst Pharm. 67:449-458. Yang, E. J., J. G. Kim, J. Y. Kim, S. C. Kim, N. H. Lee, and C. G. Hyun. 2010. Anti-inflammatory effect of chitosan oligosaccharides in RAW 264.7 cells. Cent. Eur. J. Biol. 5:95–102. Yi, P. J., C. K. Pai, and J. R. Liu. 2011. Isolation and characterization of a Bacillus licheniformis strain capable of degrading zearalenone. World J. Microbiol. Biotechnol. 27:1035-1043. Yoon, H. J., M. E. Moon, H. S. Park, S. Y. Im, and Y. H. Kim. 2007. Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells. Biochem. Biophys. Res. Commun. 358:954-959. Zhou, T. X., Y. J. Chen, J. S. Yoo, Y. Huang, J. H. Lee, H. D. Jang, S. O. Shin, H. J. Kim, J. H. Cho, and I. H. Kim. 2009. Effects of chitooligosaccharide supplementation on performance, blood characteristics, relative organ weight, and meat quality in broiler chickens. Poult. Sci. 88:593-600. Ziaei-Nejad, S., M. H. Rezaei, G. A. Takami, D. L. Lovett, A. R. Mirvaghefi, and M. Shakouri. 2006. The effect of Bacillus spp. bacteria used as probiotics on digestive enzyme activity, survival and growth in the Indian white shrimp Fenneropenaeus indicus. Aquaculture 252:516-524. Zulkifli, I., N. Abdullah, N. M. Azrin, and Y. W. Ho. 2000. Growth performance and immune response of two commercial broiler strains fed diets containing Lactobacillus cultures and oxytetracycline under heat stress conditions. Br. Poult. Sci. 41:593-597. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/63676 | - |
dc.description.abstract | 幾丁聚糖經由酵素或化學水解所產生之幾丁寡糖,其可溶於水且黏度低,並具有幾丁聚糖相似之生物活性。先前研究指出,添加幾丁寡糖可增強肉雞之生長性狀及表面消化率。基於環境污染及成本考量,以酵素水解生產幾丁寡糖被認為是較佳之方法。許多Bacillus菌種具有幾丁聚糖酶之活性,其中亦包含Bacillus licheniformis。因此,本研究擬探討飼料中添加B. licheniformis CK1及其幾丁聚糖發酵液對肉雞生長性狀之影響。
首先,為了解是否B. licheniformis CK1可使用幾丁聚糖做為碳源進行生長,及其產生幾丁聚糖酶之能力,故將其培養於含幾丁聚糖、食鹽及胰化蛋白各1%組成之培養液。結果顯示,經24小時培養後,B. licheniformis CK1可達最大菌數108 CFU/mL ,並同時具有4.7 U/mL之幾丁聚糖酶活性。 在動物試驗部分,以0日齡愛拔益加白肉雞逢機分置於對照組、B. licheniformis CK1組、B. licheniformis CK1及其幾丁聚糖發酵液組及商用幾丁寡糖組等4個組。每處理組含4重複,每重複10隻。試驗期6週,並進行二次試驗。在評估試驗中,各添加物處理組之0-6週採食量皆顯助低於對照組,故飼料轉換率顯著較高;且B. licheniformis CK1及其幾丁聚糖發酵液組不會對肉雞之血液性狀,以及各器官造成不良影響。在二次試驗中,B. licheniformis CK1及其幾丁聚糖發酵液組有較佳之飼料轉換率;亦有提升肉雞腸道中乳酸桿菌及減少大腸桿菌之趨勢,且其絨毛分布緻密完整,甚而長度也較對照組長。此外,各處理組之免疫球蛋白濃度亦較對照組為高。 綜上所述,添加B. licheniformis CK1及其幾丁聚糖發酵液可改善白肉雞隻飼料轉換率,擁有較好之營養狀態,且或許有調節肉雞免疫系統之能力。因此,B. licheniformis CK1及其幾丁聚糖發酵液有做為肉雞飼料添加物之潛力。 | zh_TW |
dc.description.abstract | Chitooligosaccharide (COS) is obtained by chemical and enzymatic hydrolysis of chitosan. COS has not only the same biological functions as chitosan, but also has lower viscosity and higher water solubility than chitosan. Furthermore, COS supplementation had been confirmed that could enhances the performance and apparent digestibility of broiler. Due to environmental pollution and cost, it is better to produce COS by enzymatic than chemical method. Several Bacillus spp., including B. licheniformis, have chitosanase activity. Thus, this study was conducted to investigate the effect of supplementation of B. licheniformis CK1 and its chitosan fermentation broth (CFB) on growth performance of broilers.
First of all, the growth and chitosanase activity of B. licheniformis CK1 cultured in medium containing 1% chitosan, 1% tryptone, and 1% sodium chloride were determined. B. licheniformis CK1 attained to maximum bacterial counts after 24 hours of incubation (108 CFU/mL) and had highest chitosanase activity after 12 hours of incubation (4.7 U/mL). Then, for the animal trial, 0-day-old Arbor Acres broilers were randomly assigned into four groups, including control group, CK1 group (supplementation of B. licheniformis CK1 in a concentration of 108 CFU/kg), CK1+CFB group (supplementation of CFB with B. licheniformis CK1 in a concentration of 108 CFU/kg), and COS group. There were four replicates of 10 broilers within each group. In the first trial, the results showed that B. licheniformis CK1 and its fermented chitosan broth supplementation significantly decreased feed intake (FI) but increased feed conversion ratio (FCR), and had no adverse effects on the organ, as well as blood characteristics. In the second trial, the results of FCR of the broilers in the CK1+CFB group during 4-6 wk and during 0-6 wk were the same as those in first trail. Compared with the control group, serum immunoglobulin G levels of broilers in the other treatment groups were slightly higher during 0-6 wk. Moreover, the broilers in the CK1+CFB group and COS group showed a slight increase of Lactobacillus counts and decrease of Escherichia coli counts in the gut microflora during 0-3 wk. The villi of broilers in the CK1 group and the CK1+CFB group were more complete, compact and higher than those in the control group or commercial chitooligosaccharides group. In summary, supplementation of B. licheniformis CK1 and its chitosan fermentation broth in broiler feed improved FCR and might possess better nutrient states. Besides, both of them perhaps could modulate immunity in broiler. These findings revealed that B. licheniformis CK1 and COS have potential for use as feed supplementations to broilers. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T17:16:11Z (GMT). No. of bitstreams: 1 ntu-101-R99626012-1.pdf: 1852723 bytes, checksum: 87610ab2c111bf83f8c5d0a9bde251c2 (MD5) Previous issue date: 2012 | en |
dc.description.tableofcontents | 中文摘要 1
英文摘要 2 序言 4 第一章、文獻探討 5 一、益生菌 5 1. 定義 5 2. 機能性 5 二、Bacillus 6 1. 簡介 6 2. Bacillus之機能性評估 6 3. 地衣芽孢桿菌特性 8 三、幾丁質、幾丁聚糖及幾丁寡糖 9 1. 簡介 9 2. 幾丁質酶(chitinase)及幾丁聚糖酶(chitosanase) 9 3. 幾丁聚糖及其衍生物之功能特性 11 四、幾丁寡糖進行免疫調節 14 1. In vitro試驗 14 2. In vivo試驗 14 第二章、材料與方法 28 第一節 B. licheniformis CK1於幾丁聚糖培養基之生長速率 28 第二節 B. licheniformis CK1幾丁聚糖酶活性分析 29 第三節 以B. licheniformis CK1及其幾丁聚糖發酵液餵飼肉雞之效果評估 31 第三章、結果與討論 38 第一節 B. licheniformis CK1於幾丁聚糖培養基之生長速率 38 第二節 B. licheniformis CK1幾丁聚糖酶活性分析 40 第三節 以B. licheniformis CK1及其幾丁聚糖發酵液餵飼肉雞之效果評估 42 一、B. licheniformis CK1及其幾丁聚糖發酵液之初始評估試驗 42 二、B. licheniformis CK1及其幾丁聚糖發酵液之試驗 52 第四章、結論 69 參考文獻 70 作者小傳 83 | |
dc.language.iso | zh-TW | |
dc.title | 添加Bacillus licheniformis CK1及其幾丁聚糖發酵液對白肉雞生長性狀之影響 | zh_TW |
dc.title | Effect of supplementation of Bacillus licheniformis CK1 and its chitosan fermentation broth on growth performance of broilers | en |
dc.type | Thesis | |
dc.date.schoolyear | 100-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 余碧,陳明汝,彭及忠,劉啟德 | |
dc.subject.keyword | Bacillus licheniformis,幾丁聚糖,肉雞,幾丁寡糖, | zh_TW |
dc.subject.keyword | Bacillus licheniformis,chitosan,broilers,chitooligosaccharide, | en |
dc.relation.page | 83 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2012-08-18 | |
dc.contributor.author-college | 生物資源暨農學院 | zh_TW |
dc.contributor.author-dept | 動物科學技術學研究所 | zh_TW |
顯示於系所單位: | 動物科學技術學系 |
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