請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/63536
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 胡名霞(Ming-Hsia Hu) | |
dc.contributor.author | Wai-Keong Ho | en |
dc.contributor.author | 何偉強 | zh_TW |
dc.date.accessioned | 2021-06-16T17:13:42Z | - |
dc.date.available | 2013-09-19 | |
dc.date.copyright | 2012-09-19 | |
dc.date.issued | 2012 | |
dc.date.submitted | 2012-08-20 | |
dc.identifier.citation | Abellan Van Kan G. (2009). Epidemiology and consequences of sarcopenia. The journal of nutrition, health & aging, 13(8), 708-712.
Ahmed N., Mandel R., & Fain M. J. (2007). Frailty: an emerging geriatric syndrome. The American journal of medicine, 120(9), 748-753. Avila-Funes J. A., Pina-Escudero S. D., Aguilar-Navarro S., Gutierrez-Robledo L. M., Ruiz-Arregui L., & Amieva H. (2011). Cognitive Impairment and Low Physical Activity Are the Components of Frailty More Strongly Associated with Disability. Journal of Nutrition Health & Aging, 15(8), 683-689. Bandeen-Roche K., Xue Q. L., Ferrucci L., Walston J., Guralnik J. M., Chaves P., Zeger S. L., & Fried L. P. (2006). Phenotype of frailty: Characterization in the women's health and aging studies. Journals of Gerontology Series a-Biological Sciences and Medical Sciences, 61(3), 262-266. Baumgartner R. N., Koehler K. M., Gallagher D., Romero L., Heymsfield S. B., Ross R. R., Garry P. J., & Lindeman R. D. (1998). Epidemiology of Sarcopenia among the Elderly in New Mexico. American Journal of Epidemiology, 147(8), 755-763. Binder E. F., Yarasheski K. E., Steger-May K., Sinacore D. R., Brown M., Schechtman K. B., & Holloszy J. O. (2002). Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial. Journal of the American Geriatrics Society, 50(12), 1921-1928. Binder E. F., Yarasheski K. E., Steger-May K., Sinacore D. R., Brown M., Schechtman K. B., & Holloszy J. O. (2005). Effects of progressive resistance training on body composition in frail older adults: results of a randomized, controlled trial. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60(11), 1425-1431. Blaum C. S., Xue Q. L., Michelon E., Semba R. D., & Fried L. P. (2005). The Association Between Obesity and the Frailty Syndrome in Older Women: The Women's Health and Aging Studies. Journal of the American Geriatrics Society, 53(6), 927-934. Bortz W. M. (2002). A conceptual framework of frailty: a review. The journals of gerontology. Series A, Biological sciences and medical sciences, 57(5), M283-288. Campbell A. J., Borrie M. J., & Spears G. F. (1989). Risk Factors for Falls in a Community-Based Prospective Study of People 70 Years and Older. Journal of Gerontology, 44(4), M112-M117. Chang C. I., Chan D. C., Kuo K. N., Hsiung C. A., & Chen C. Y. (2011). Prevalence and correlates of geriatric frailty in a northern Taiwan community. Journal of the Formosan Medical Association, 110(4), 247-257. Chen B. B., Shih T. T., Hsu C. Y., Yu C. W., Wei S. Y., Chen C. Y., & Wu C. H. (2011). Thigh muscle volume predicted by anthropometric measurements and correlated with physical function in the older adults. The journal of nutrition, health & aging, 15(6), 433-438. Chien C. P., & Cheng T. A. (1985). Depression in Taiwan: epidemiological survey utilizing CES-D. Seishin shinkeigaku zasshi, 87(5), 335-338. Chin J. M. M., Paw A., de Jong N., Schouten E. G., Hiddink G. J., & Kok F. J. (1999). Effectiveness and feasibility of an all-round, progressive exercise program for frail elderly. Journal of aging and physical activity, 7(3), 328-329. Dunlop D. D., Hughes S. L., & Manheim L. M. (1997). Disability in activities of daily living: patterns of change and a hierarchy of disability. American Journal of Public Health, 87(3), 378-383. Edwards M., Feightner J., & Goldsmith C. H. (1995). Interrater Reliability of Assessments Administered by Individuals with and without a Background in Health-Care. Occupational Therapy Journal of Research, 15(2), 103-110. Espinoza S., Jung I., & Hazuda H. (2012). Frailty Transitions in the San Antonio Longitudinal Study of Aging. Journal of the American Geriatrics Society, 60(4), 652-660. Espinoza S., & Walston J. D. (2005). Frailty in older adults: insights and interventions. Cleveland Clinic Journal of Medicine, 72(12), 1105-1112. Fairhall N., Sherrington C., Kurrle S. E., Lord S. R., & Cameron I. D. (2011). ICF participation restriction is common in frail, community-dwelling older people: an observational cross-sectional study. Physiotherapy, 97(1), 26-32. Ferrucci L., Guralnik J. M., Simonsick E., Salive M. E., Corti C., & Langlois J. (1996). Progressive versus catastrophic disability: a longitudinal view of the disablement process. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 51(3), M123-130. Ferrucci L., Guralnik J. M., Studenski S., Fried L. P., Cutler G. B., Jr., & Walston J. D. (2004). Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. Journal of the American Geriatrics Society, 52(4), 625-634. Ferrucci L., Izmirlian G., Leveille S., Phillips C. L., Corti M. C., Brock D. B., & Guralnik J. M. (1999). Smoking, physical activity, and active life expectancy. American Journal of Epidemiology, 149(7), 645-653. Fleming K. C., Evans J. M., Weber D. C., & Chutka D. S. (1995). Practical functional assessment of elderly persons: a primary-care approach. Mayo Clinic Proceedings, 70(9), 890-910. Fried L. P., Ferrucci L., Darer J., Williamson J. D., & Anderson G. (2004). Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. The journals of gerontology. Series A, Biological sciences and medical sciences, 59(3), 255-263. Fried L. P., Tangen C. M., Walston J., Newman A. B., Hirsch C., Gottdiener J., Seeman T., Tracy R., Kop W. J., Burke G., & McBurnie M. A. (2001). Frailty in older adults: evidence for a phenotype. The journals of gerontology. Series A, Biological sciences and medical sciences, 56(3), M146-156. Fritz S., & Lusardi M. (2009). White paper: 'walking speed: the sixth vital sign'. Journal of geriatric physical therapy, 32(2), 46-49. Fugate W. N., LaCroix A. Z., Gray S. L., Aragaki A., Cochrane B. B., Brunner R. L., Masaki K., Murray A., & Newman A. B. (2005). Frailty: Emergence and Consequences in Women Aged 65 and Older in the Women's Health Initiative Observational Study. Journal of the American Geriatrics Society, 53(8), 1321-1330. Fulop T., Larbi A., Witkowski J. M., McElhaney J., Loeb M., Mitnitski A., & Pawelec G. (2010). Aging, frailty and age-related diseases. Biogerontology, 11(5), 547-563. Gill T. M., Baker D. I., Gottschalk M., Peduzzi P. N., Allore H., & Byers A. (2002). A program to prevent functional decline in physically frail, elderly persons who live at home. The New England Journal of Medicine, 347(14), 1068-1074. Gill T. M., Gahbauer E. A., Allore H. G., & Han L. (2006). Transitions between frailty states among community-living older persons. Archives of internal medicine, 166(4), 418-423. Gill T. M., Gahbauer E. A., Han L., & Allore H. G. (2010). Trajectories of Disability in the Last Year of Life. New England Journal of Medicine, 362(13), 1173-1180. Gill T. M., Richardson E. D., & Tinetti M. E. (1995). Evaluating the risk of dependence in activities of daily living among community-living older adults with mild to moderate cognitive impairment. The journals of gerontology. Series A, Biological sciences and medical sciences, 50(5), M235-241. Gill T. M., Robison J. T., & Tinetti M. E. (1997). Predictors of recovery in activities of daily living among disabled older persons living in the community. Journal of General Internal Medicine, 12(12), 757-762. Gobbens R. J., & van Assen M. A. (2012). Frailty and its prediction of disability and health care utilization: The added value of interviews and physical measures following a self-report questionnaire. Archives of Gerontology and Geriatrics. Graham J. E., Al Snih S., Berges I. M., Ray L. A., Markides K. S., & Ottenbacher K. J. (2009). Frailty and 10-Year Mortality in Community-Living Mexican American Older Adults. Gerontology, 55(6), 644-651. Gresham G. E., Phillips T. F., & Labi M. L. (1980). ADL status in stroke: relative merits of three standard indexes. Archives of physical medicine and rehabilitation, 61(8), 355-358. Guralnik J. M., Lacroix A. Z., Branch L. G., Kasl S. V., & Wallace R. B. (1991). Morbidity and Disability in Older Persons in the Years Prior to Death. American Journal of Public Health, 81(4), 443-447. Guralnik J. M., Simonsick E. M., Ferrucci L., Glynn R. J., Berkman L. F., Blazer D. G., Scherr P. A., & Wallace R. B. (1994). A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. Journal of gerontology, 49(2), M85-94. Hadley E. C., Ory M. G., Suzman R., & Weindruch R. (1993). Physical Frailty - a Treatable Cause of Dependence in Old-Age - Foreword. Journals of Gerontology, 48, R7-R8. Hamerman D. (1999). Toward an understanding of frailty. Annals of internal medicine, 130(11), 945-950. Hardy S. E., & Gill T. M. (2005). Factors associated with recovery of independence among newly disabled older persons. Archives of internal medicine, 165(1), 106-112. Hazzard W. R., & Halter J. B. (2009). Hazzard's geriatric medicine and gerontology (6th ed.). New York: McGraw-Hill Medical. Heppenstall C. P., Wilkinson T. J., Hanger H. C., & Keeling S. (2009). Frailty: dominos or deliberation? The New Zealand medical journal, 122(1299), 42-53. Hollman J. H., Beckman B. A., Brandt R. A., Merriwether E. N., Williams R. T., & Nordrum J. T. (2008). Minimum detectable change in gait velocity during acute rehabilitation following hip fracture. Journal of geriatric physical therapy, 31(2), 53-56. Jagger C., Arthur A. J., Spiers N. A., & Clarke M. (2001). Patterns of onset of disability in activities of daily living with age. Journal of the American Geriatrics Society, 49(4), 404-409. Janssen I., Heymsfield S. B., & Ross R. (2002). Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. Journal of the American Geriatrics Society, 50(5), 889-896. Katz M. H. (2006). Setting up a multivariable analysis. In: Multivariable analysis-A practical guide for clinicians (2 ed., pp. 77-95): Cambridge University Press. Kim M. J., Yabushita N., Kim M. K., Nemoto M., Seino S., & Tanaka K. (2010). Mobility performance tests for discriminating high risk of frailty in community-dwelling older women. Archives of Gerontology and Geriatrics, 51(2), 192-198. Kirshner B., & Guyatt G. (1985). A methodological framework for assessing health indices. Journal of Chronic Diseases, 38(1), 27-36. Kornerbitensky N., Wooddauphinee S., Siemiatycki J., Shapiro S., & Becker R. (1994). Health-Related Information Postdischarge - Telephone Versus Face-to-Face Interviewing. Archives of physical medicine and rehabilitation, 75(12), 1287-1296. Kuh D. (2007). A life course approach to healthy aging, frailty, and capability. The journals of gerontology. Series A, Biological sciences and medical sciences, 62(7), 717-721. Landi F., Abbatecola A. M., Provinciali M., Corsonello A., Bustacchini S., Manigrasso L., Cherubini A., Bernabei R., & Lattanzio F. (2010). Moving against frailty: does physical activity matter? Biogerontology, 11(5), 537-545. Landi F., Onder G., Carpenter I., Cesari M., Soldato M., & Bernabei R. (2007). Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study. Journal of clinical epidemiology, 60(5), 518-524. Lang P. O., Michel J. P., & Zekry D. (2009). Frailty syndrome: a transitional state in a dynamic process. Gerontology, 55(5), 539-549. Lee J. S. W., Auyeung T. W., Leung J., Kwok T., Leung P. C., & Woo J. (2011). Physical Frailty in Older Adults Is Associated with Metabolic and Atherosclerotic Risk Factors and Cognitive Impairment Independent of Muscle Mass. Journal of Nutrition Health & Aging, 15(10), 857-862. Leng S. X., Cappola A. R., Andersen R. E., Blackman M. R., Koenig K., Blair M., & Walston J. D. (2004). Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty. Aging Clinical and Experimental Research, 16(2), 153-157. Leng S. X., Yang H. L., & Walston J. D. (2004). Decreased cell proliferation and altered cytokine production in frail older adults. Aging Clinical and Experimental Research, 16(3), 249-252. Ling C. H., Taekema D., de Craen A. J., Gussekloo J., Westendorp R. G., & Maier A. B. (2010). Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study. Canadian Medical Association journal 182(5), 429-435. Liston R. A. L., & Brouwer B. J. (1996). Reliability and validity of measures obtained from stroke patients using the balance master. Archives of physical medicine and rehabilitation, 77(5), 425-430. Lord S. R., Murray S. M., Chapman K., Munro B., & Tiedemann A. (2002). Sit-to-stand performance depends on sensation, speed, balance, and psychological status in addition to strength in older people. Journals of Gerontology Series a-Biological Sciences and Medical Sciences, 57(8), M539-M543. Mahoney F. I., & Barthel D. W. (1965). Functional evaluation : the Barthel Index. Maryland state medical journal, 14, 61-65. Manton K. G. (1988). A Longitudinal-Study of Functional Change and Mortality in the United-States. Journals of Gerontology, 43(5), S153-S161. Melis R. J., van Eijken M. I., Borm G. F., Wensing M., Adang E., van de Lisdonk E. H., van Achterberg T., & Olde Rikkert M. G. (2005). The design of the Dutch EASYcare study: a randomised controlled trial on the effectiveness of a problem-based community intervention model for frail elderly people BMC Health Serv Res, 5, 65. Murphy J., Berwick D. M., Weinstein M. C., Borus J. F., Budman S. H., & Klerman G. L. (1987). Performance of screening and diagnostic tests: Application of receiver operating characteristic analysis. Archives of General Psychiatry, 44(6), 550-555. Nemoto M., Yabushita N., Kim M.-j., Matsuo T., Seino S., & Tanaka K. (2011). Assessment of vulnerable older adults’ physical function according to the Japanese Long-Term Care Insurance (LTCI) system and Fried's criteria for frailty syndrome. Archives of Gerontology and Geriatrics(0). Nevitt M., Cummings S. R., Kidd S., & Black D. (1989). Risk factors for recurrent nonsyncopal falls: A prospective study. The Journal of the American Medical Association, 261(18), 2663-2668. Organization W. H. (2011). Health topics-Disabilities Retrieved 2/18, 2012, from http://www.who.int/topics/disabilities/en/ Ostir G. V., Ottenbacher K. J., & Markides K. S. (2004). Onset of frailty in older adults and the protective role of positive affect. Psychology and Aging, 19(3), 402-408. Ottenbacher K. J., Ostir G. V., Peek M. K., Snih S. A., Raji M. A., & Markides K. S. (2005). Frailty in Older Mexican Americans. Journal of the American Geriatrics Society, 53(9), 1524-1531. Paw M. J. M. C., Dekker J. M., Feskens E. J. M., Schouten E. G., & Kromhout D. (1999). How to Select a Frail Elderly Population? A Comparison of Three Working Definitions. Journal of clinical epidemiology, 52(11), 1015-1021. Peolsson A., Hedlund R., & Oberg B. (2001). Intra- and inter-tester reliability and reference values for hand strength. Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine, 33(1), 36-41. Perera S., Mody S. H., Woodman R. C., & Studenski S. A. (2006). Meaningful Change and Responsiveness in Common Physical Performance Measures in Older Adults. Journal of the American Geriatrics Society, 54(5), 743-749. Podsiadlo D., & Richardson S. (1991a). The timed 'Up & Go': a test of basic functional mobility for frail elderly persons. Journal of the American Geriatrics Society, 39(2), 142-148. Podsiadlo D., & Richardson S. (1991b). The Timed up and Go - a Test of Basic Functional Mobility for Frail Elderly Persons. Journal of the American Geriatrics Society, 39(2), 142-148. Portney L. G., & Watkins M. P. (2008). Multivariate Analysis Foundations of Clinical Research: Applications to Practice (3 ed., pp. 701): Prentice Hall. Radloff L. S. (1977). The CES-D Scale. Applied Psychological Measurement, 1(3), 385-401. Rankin S. H., & Galbraith M. E. (1993). Reliability and validity data for a Chinese translation of the Center for Epidemiological Studies-Depression. Psychological Reports, 73(3f), 1291-1298. Reuben D. B. (2002). Organizational interventions to improve health outcomes of older persons. Medical Care, 40(5), 416-428. Robinson T. N., Wu D. S., Stiegmann G. V., & Moss M. (2011). Frailty predicts increased hospital and six-month healthcare cost following colorectal surgery in older adults. American journal of surgery, 202(5), 511-514. Rochat S., Cumming R. G., Blyth F., Creasey H., Handelsman D., Le Couteur D. G., Naganathan V., Sambrook P. N., Seibel M. J., & Waite L. (2010). Frailty and use of health and community services by community-dwelling older men: the Concord Health and Ageing in Men Project. Age and Ageing, 39(2), 228-233. Rockwood K., Cosway S., Stolee P., Kydd D., Carver D., Jarrett P., & O'Brien B. (1994). Increasing the recognition of delirium in elderly patients. Journal of the American Geriatrics Society, 42(3), 252-256. Rosenberg I. H. (1997). Sarcopenia: origins and clinical relevance. The Journal of nutrition, 127(5 Suppl), 990S-991S. Rothman M. D., Leo-Summers L., & Gill T. M. (2008). Prognostic Significance of Potential Frailty Criteria. Journal of the American Geriatrics Society, 56(12), 2211-2216. Roubenoff R. (2000). Sarcopenic obesity: Does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis. Annals of the New York Academy of Sciences, 904, 553-557. Rowe J. W., & Kahn R. L. (1987). Human aging: usual and successful. Science, 237(4811), 143-149. Runge M., & Hunter G. (2006). Determinants of musculoskeletal frailty and the risk of falls in old age. Journal of musculoskeletal & neuronal interactions, 6(2), 167-173. Sergi G., Sarti S., Mosele M., Ruggiero E., Imoscopi A., Miotto F., Bolzetta F., Inelmen E. M., Manzato E., & Coin A. (2011). Changes in healthy elderly women's physical performance: a 3-year follow-up. Experimental gerontology, 46(11), 929-933. Shumway-Cook A., Brauer S., & Woollacott M. (2000). Predicting the Probability for Falls in Community-Dwelling Older Adults Using the Timed Up & Go Test. Physical Therapy, 80(9), 896-903. Sirola J., Pitkala K. H., Tilvis R. S., Miettinen T. A., & Strandberg T. E. (2011). Definition of Frailty in Older Men According to Questionnaire Data (RAND-36/SF-36): The Helsinki Businessmen Study. The journal of nutrition, health & aging, 15(9), 783-787. Steffen T. M., Hacker T. A., & Mollinger L. (2002). Age- and Gender-Related Test Performance in Community-Dwelling Elderly People: Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and Gait Speeds. Physical Therapy, 82(2), 128-137. Studenski S., Perera S., Wallace D., Chandler J. M., Duncan P. W., Rooney E., Fox M., & Guralnik J. M. (2003). Physical performance measures in the clinical setting. Journal of the American Geriatrics Society, 51(3), 314-322. Taekema D. G., Gussekloo J., Maier A. B., Westendorp R. G. J., & de Craen A. J. M. (2010). Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old. Age and Ageing, 39(3), 331-337. Taylor H. L., Jacobs Jr D. R., Schucker B., Knudsen J., Leon A. S., & Debacker G. (1978). A questionnaire for the assessment of leisure time physical activities. Journal of Chronic Diseases, 31(12), 741-755. Thapa P. B., Gideon P., Brockman K. G., Fought R. L., & Ray W. A. (1996). Clinical and biomechanical measures of balance as fall predictors in ambulatory nursing home residents. Journals of Gerontology Series a-Biological Sciences and Medical Sciences, 51(5), M239-M246. Thapa P. B., Gideon P., Fought R. L., Kormicki M., & Ray W. A. (1994). Comparison of Clinical and Biomechanical Measures of Balance and Mobility in Elderly Nursing-Home Residents. Journal of the American Geriatrics Society, 42(5), 493-500. Topinkova E. (2008). Aging, disability and frailty. Annals of Nutrition and Metabolism, 52, 6-11. van den Beld W. A., van der Sanden G. A. C., Sengers R. C. A., Verbeek A. L. M., & Gabreels F. J. M. (2006). Validity and reproducibility of the Jamar dynamometer in children aged 4-11 years. Disability and Rehabilitation, 28(21), 1303-1309. Verbrugge L. M., Reoma J. M., & Gruber-Baldini A. L. (1994). Short-term dynamics of disability and well-being. Journal of health and social behavior, 35(2), 97-117. Visser M., Deeg D. J., Lips P., Harris T. B., & Bouter L. M. (2000). Skeletal muscle mass and muscle strength in relation to lower-extremity performance in older men and women. Journal of the American Geriatrics Society, 48(4), 381-386. Walston J., McBurnie M. A., Newman A., Tracy R. P., Kop W. J., Hirsch C. H., Gottdiener J., Fried L. P., & for the Cardiovascular Health Study Investigators. (2002). Frailty and Activation of the Inflammation and Coagulation Systems With and Without Clinical Comorbidities: Results From the Cardiovascular Health Study. Archives of internal medicine, 162(20), 2333-2341. Washburn R. A., Smith K. W., Jette A. M., & Janney C. A. (1993). The Physical-Activity Scale for the Elderly (Pase) - Development and Evaluation. Journal of clinical epidemiology, 46(2), 153-162. Whitson H. E., Purser J. L., & Cohen H. J. (2007). Frailty thy name is ... Phrailty? The journals of gerontology. Series A, Biological sciences and medical sciences, 62(7), 728-730. Wolf S. L., O'Grady M., Easley K. A., Guo Y., Kressig R. W., & Kutner M. (2006). The influence of intense Tai Chi training on physical performance and hemodynamic outcomes in transitionally frail, older adults. The journals of gerontology. Series A, Biological sciences and medical sciences, 61(2), 184-189. Wu S. C., Leu S. Y., & Li C. Y. (1999). Incidence of and predictors for chronic disability in activities of daily living among older people in Taiwan. Journal of the American Geriatrics Society, 47(9), 1082-1086. Zhang Y., & Herman B. (2002). Apoptosis and successful aging. Mechanisms of Ageing and Development, 123(6), 563-565. 行政院衛生署. (2011). 國民長期照顧需要調查. 台灣. 吳淑瓊, & 張明正. (1997). 台灣老人健康照護之現況分析 台灣省家庭計畫研究所台灣老人研究叢刊系列 (pp. 33-43). 台北: 國立台灣大學. 呂貝蕾, 張淑玲, 陳晶瑩, 吳治勳, 張靜怡, & 陳慶餘. (2010). 門診慢性病老人衰弱症之分析. 台灣老年醫學暨老年學雜誌, 5(1), 36-49. 林正修. (1997). 某醫學中心家庭醫學科門診病患憂鬱症之盛行率與相關因素的探討. 碩士論文, 國立台灣大學, 台北. 林清泉, & 呂德財. (1990). 影響握力因素研究. 崑山技術學院學報, 3(2), 135-139. 邱宜君, 林宜萱, 李庭蓁, & 胡名霞. (2009). 使用Jamar握力器評估抓握動態耐力之再測信度. 物理治療, 34(6), 357-363. 徐慧娟. (2003). 成功老化:老年健康的正向觀點. 社區發展季刊, 103, 252-260. 劉影梅. (2004). 國際身體活動量表台灣中文版之發展與信效度驗證. 博士論文, 國立台灣大學, 台北. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/63536 | - |
dc.description.abstract | 衰弱症是指多系統的惡化(multisystem deterioration)和生理性的儲備(physiological reserves)下降,也是跌倒、行動不能(immobility)、住院、機構化、死亡的高危險群。衰弱症老人的生活功能和生活品質都會受重大的影響,日常生活需要依賴,進機構率和住院率都比一般老人來得高,使整個醫療體系經濟負擔加重。因此對於台灣衰弱老人的預防,早期偵測,給予介入,逆轉其惡化過程,是極為重要的議題。
老人的體能表現可以反映個人的身體健康狀況,本篇研究目的是以老人的體能表現,如計時起走測驗、行走速度、握力、計時坐到站測試等測試結果作為預測因子,探討與比較衰弱老人和失能老人的體能表現特徵,並預測老人在六個月和二十四個月內衰弱和失能的起伏。進一步,預測衰弱老人進入失能狀態的機率,分析何種體能表現的變異最大,以提供日後給予介入和訓練的參考。 本研究使用國家衛生研究院群體健康科學研究所老人醫學研究組進行中的縱向前溯性觀察研究(longitudinal prospective observational study)的資料作分析,資料收集由2007年5月至2009年1月,在台大醫院家庭醫學部門診及老年醫學部門診徵召個案,基本資料收集後,進行初次的衰弱、失能評估和各項體能測量,並每半年追蹤評估一次,共追蹤兩年。本篇使用邏輯式迴歸分析(Logistic regression analysis) (SPSS PC Version 16.0)進行資料處理與分析,以計時起走測驗、行走速度、握力、計時坐到站測試等體能表現作為自變項,建立各個迴歸模式。以單變項方式來描述體能表現與各個預測變數之間的關係,並進一步以逐步多變項羅吉斯廻歸分析(stepwise multivariate logistic regression analysis)探討何種體能評估最具影響力,並加入年齡、性別、慢性疾病數大於或等於5種、使用慢性藥物數目大於或等於8種等混淆因子(confounding factor )的變項作為共變項。依變項分別為(1)個案六個月和二十四個月內是否發生衰弱起伏,(2)六個月和二十四個月內是否發生失能起伏,(3) 六個月和二十四個月內衰弱老人是否進入失能。 共188位個案完成二十四個月的追蹤,有93位(49.47%)男性,95位(50.53%)女性,平均年齡為78.78±6.26歲(67-90歲)。身體質量指數BMI平均值為25.51±3.75 (16.4-39.2)。沒有衰弱、衰弱傾向、衰弱的個案分別為53位(27.53%)、117位(62.43%)、19位(10.05%)。沒有失能與失能人數為114位(76.2%)和45位(23.8%)。個案的衰弱起伏主要是從沒有衰弱進入衰弱傾向居多(55.6~69.6%),其次為衰弱傾向進入衰弱(14.7~42.2%),幾乎沒有個案從沒有衰弱直接進入衰弱狀態(0~2.2%)。個案的失能起伏率為3.8~12.3%。衰弱老人退化至失能的比率為4.1~14.9%。研究結果顯示:(1) 不同衰弱狀態和失能狀態的個案間,行走速度、計時起走測驗、握力、計時坐到站測試(10秒內完成3次)等體能表現均達顯著差異。(2)單變項羅吉斯廻歸分析顯示,老人六個月和二十四個月內發生衰弱起伏、失能起伏、衰弱老人進入失能狀態的預測模式中握力和行走速度為顯著的預測因子,計時起走測驗則只有在六個月內的失能起伏和六個月內衰弱老人進入失能的預測模式中具有顯著意義。(3)多變項羅吉斯廻歸分析顯示,在控制了其他共變量和體能表現的情況下,在衰弱起伏的預測模式中,握力和行走速度為顯著因子。失能起伏的預測模式中,只有行走速度為顯著因子。衰弱老人進入失能的預測模式中沒有達顯著的因子。 本研究結果指出體能表現的評估對於老人的衰弱和失能具有區辨性指標的能力,臨床上可作為初步的篩檢測試(screening test)以找出衰弱和失能的高危族群個案,若篩檢結果為正,則可進一步作其他檢查或給予介入,以逆轉或延緩老人的衰弱退化,預防失能。體能表現的評估能有效預測老人在短期(6個月內)或長期(24個月內)發生衰弱和失能起伏的機率,其中握力、行走速度最重要的指標,計時起走測驗則只有在預測老人短期失能起伏上,也許是一個良好的參考指標。本研究未能找出最具影響力的體能指標來預測衰弱老人退化轉變為失能狀態的發生機率,但以單變項的體能表現來看,握力、行走速度能預測都能預測衰弱老人在短期或長期進入失能的機率,計時起走測驗則只能預測衰弱老人短期的轉變。 | zh_TW |
dc.description.abstract | Frailty is a common geriatric condition that is multisystem deterioration and loss of physiological reserve. The prevalence of frailty was from 11.0% to 14.9% in Taiwan. Several studies confirmed that frailty was associated with adverse health outcomes. It is becoming recognized that frailty may be a pre-disability state with multidimensional and unstable characteristics in the dynamic progression from robustness to multi-organ functional decline. Many common geriatric syndromes have been proposed to contribute to frailty, such as sarcopenia, malnutrition, osteoporosis, and depressive symptoms etc.With advancing age, physical performance declines in older adults. The assessment of physical performance is a critical component in the evaluation of older persons in both clinical and research, because that can represent the personal health statues. Performance based measures should be included in screening protocol to identify older adults who are at high risk to become frail or transit from frailty to disability, how to early detect and to develop effective intervention on frailty, to reverse the deterioration process is a very important issue.
The aims of this study were (1) to compare the physical performance between different frail states and disabled states, (2) to establish a prediction model for frailty transition and disability transition, furthermore, to predict transition from frailty to disability using physical performance measurements. This present study employed data from the Division of Geriatric research, Institute of Population Health Sciences, National Health Research Institutes, an ongoing prospective, observational study of 65 years and older adults between May 2007and January 2009. Fried's phenotype and Barthel index were used to identify frail and disabled older adults in baseline evaluation. Physical performance, including grip strength, timed chair rise up test (3times/10s), walking speed, time up and go test, were evaluated at baseline. Data were analyzed using forward stepwise binary logistic regression model that performance measure as independent variables and frailty, disability, transition from frailty to disability as dependent variables. Only 188 participants completed all the baseline and follow up tests were reported. 93 (49.47%) male, 95 (50.53%) female. Mean age was 78.78 ± 6.26 years (67-90 years). Non frail, prefrail and frail peoples were 53 (27.53%), 117 (62.43%), 19 (10.05%). No disabled and disabled peoples were 114 (76.2%) and 45 (23.8%). The results showed that: (1) there were significant differences in physical performances between different frail states and diffetent disabled states, (2) Univariate logistic regression analysis showed that, grip strength and walking speed were significant predictors for frailty transition, disability transition and transition from frailty to disability. Timed up and go test was significant predictors for disability transition and transition from frailty to disability during 6months. (3) Multivariate logistic regression analysis showed that, grip strength (β=-0.06, odds ratio =0.94, 95%CI= 0.89-0.98, p=0.005) and walking speed (β=-1.32, odds ratio =0.27, 95% CI= 0.08-0.89, p=0.03) were significant predictors for frailty transition. In the prediction of disability transition, walking speed (β=-3.48, odds ratio =0.03, 95% CI= 0.01-0.01, p<0.001) was the only significant predictor. There hadn’t find any significant predictors in the prediction model of transition from frailty to disability, Physical performance assessments have the ability to discriminate the high risk frail or disabled older adults among clients of geriatric clinics, and can be used as a screening test. If the screening results are positive, then further for other examinations or interventions to reverse or delay the degradation in the older adults. Grip strength and walking speed are the important indicators for predict the occurrence probability of frailty transition and disability transition. Timed up and go test is the indicator for the short-term disability transition. The presented study failed to identify the most influential physical indicators to predict the transition from frailty to disability. However, univariate logistic regression analysis showed that, grip strength and walking speed can predict transition from frailty to disability. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T17:13:42Z (GMT). No. of bitstreams: 1 ntu-101-R99428011-1.pdf: 4219800 bytes, checksum: 368759e85bac6dc08dcdc54a63416303 (MD5) Previous issue date: 2012 | en |
dc.description.tableofcontents | 目錄
論文審定書 I 誌謝 II 中文摘要 III ABSTRACT VI 第一章 前言 1 第一節 研究背景 1 第二節 研究目的 4 第三節 研究問題與假設 4 衰弱體能表現的差異與衰弱起伏(frailty transition)的預測 5 失能體能表現的差異與失能起伏(disability transition)的預測 6 衰弱老人進入失能狀態的預測 8 第四節 研究重要性 9 第二章 文獻回顧 11 第一節 衰弱的定義 11 第二節 失能的定義 14 第三節 老化、衰弱與失能的關係 16 第四節 衰弱的相關因子 18 生理性因子(physiologic factors)(圖 5) 18 肌肉減少症 18 內分泌系統 19 免疫系統 20 肥胖 20 相關疾病/合併症 (medical illness/comorbidity) 21 社會人口學與心理學因子(sociodemographic and psychological factors) 21 第五節 衰弱老人的體能表現 22 第六節 評估量表與工具介紹 24 1. 衰弱評估 24 失能評估 27 體能評估 29 第三章 研究方法 34 第一節 研究設計 34 第二節 研究對象 34 第三節 評估方式 35 基本評估 35 衰弱評估 36 失能評估 38 體能表現評估測量 39 第四節 資料處理與統計分析 40 第四章 結果分析 45 第一節 受試者基本特徵 45 全體受試者 45 不同衰弱狀態之受試者基本特徵比較 47 不同失能狀態之受試者基本特徵比較 48 退出研究之受試者與完成追蹤之受試基本特徵與體能表現比較 48 第二節 非衰弱、衰弱傾向、衰弱老人的體能差異 49 第三節 失能與沒有失能老人的體能差異 50 第四節 老人衰弱狀態起伏的預測分析 51 第五節 老人失能狀態起伏的預測分析 52 第六節 衰弱老人進入失能狀態的預測分析 53 第七節 體能表現篩檢老人發生衰弱、失能起伏的接收者操作特徵曲線分析 ……………………………………………………………….. 54 第五章 討論 56 第一節 老人短期和長期的衰弱起伏與失能起伏比率 56 第二節 以衰弱標準和失能狀態區分的老人之間體能表現的差異 59 第三節 短期或長期內老人發生衰弱起伏和失能起伏的預測 60 衰弱起伏的預測 60 失能起伏的預測 63 第四節 衰弱老人進入失能狀態的預測 66 第五節 研究限制 67 第六節 臨床應用與本來研究方向 69 第六章 結論 71 參考文獻 72 THEORETICAL FRAMEWORK 92 LIST OF FIGURES 93 LIST OF TABLE 114 附錄 132 圖目錄 圖 1失能、共病與衰弱的關係(Fried et al., 2001) 93 圖 2衰弱的發展過程(Lang et al., 2009) 94 圖 3衰弱的生理性因素(physiological factor)和社會心理性因素(psychosocial factor)的關係(Whitson et al., 2007) 95 圖 4 老化、衰弱與失能的關係和機轉(Fulop et al., 2010) 96 圖 5衰弱的生理因素(Espinoza & Walston, 2005) 97 圖 6衰弱症臨床症狀的循環(Fried et al., 2001) 98 圖 7高風險衰弱組與低風險組的體能差異(A)5次坐到站所需的時間(B)踏步(C)快走速度(D)一般走路速度(Kim et al., 2010) 99 99 圖 8區分衰弱高危族群的最佳切點(敏感度和特異度的交點)(A)5次坐到站所需的時間(B)踏步(C)快走速度(D)一般走路速度(Kim et al., 2010) 100 圖 9收案流程圖 101 圖 10 The difference of walking speed between non frail, pre-frail and frail older adults 102 圖 11 The difference of TUG score between non frail, pre-frail and frail older adults 103 圖 12 The difference of grip strength between non frail, pre-frail and frail older adults 104 圖 13 The difference of walking speed between non-disabled and disabled older adults 105 圖 14 The difference of TUG score between non-disabled and disabled older adults 106 圖 15 The difference of grip strength between non-disabled and disabled older adults 107 圖 16 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 6 months frailty transition 108 圖 17 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 24 months frailty transition 109 圖 18 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 6 months disability transition 110 圖 19 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 24 months disability transition 111 圖 20 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 6 months transition from frailty to disability 112 圖 21 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUGT ability to classify the risk of 24 months transition from frailty to disability 113 表目錄 表 1衰弱判定的5個向度 114 表 2 Characteristics of study participants 115 表 3 Characteristics and basic data of study participants categorized by frailty status (n=312) 116 表 4 Characteristics and basic data of study participants categorized by disability status (n=312) 117 表 5 Baseline physical performance comparison categorized by frailty status 118 表 6 Baseline physical performances comparison categorized by disability status 119 表 7Characteristics comparison between participants of dropout and participants of finish follow up during 24 months 120 表 8 Baseline physical performances comparison between participants of dropout and participants of finish follow up during 24 months 121 表 9 Proportion of disability categorized by frailty status at baseline 122 表 10 Proportion of disability categorized by frailty status at 6months 123 表 11 Proportion of disability categorized by frailty status at 24months 124 表 12 Frailty and disability transition rate during 6months and 24 months 125 表 13 Binary logistic regression analysis for frailty transition: 126 表 14. Binary logistic regression analysis for disability transition 127 表 15 Binary logistic regression analysis for transition from frailty to disability: 128 表 16 Receiver operator curve analyses for discriminative validity of the walking speed,grip strength, TUG ability to classify the risk of frailty transition 129 表 17 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUG ability to classify the risk of disability transition 130 表 18 Receiver operator curve analyses for discriminative validity of the walking speed, grip strength, TUG ability to classify the risk of transition from frailty to disability 131 附錄 附錄 1基本資料 132 附錄 2台灣活動量調查自填短版問卷(Taiwan International Physical Activity Questionnaire- short form, IPAQ) 133 附錄 3衰弱評估與體能表現評估 134 附錄 4失能評估:巴氏量表 135 附錄 5臨床試驗受試者說明及同意書 136 附錄 6研究倫理委員會同意書 139 | |
dc.language.iso | zh-TW | |
dc.title | 體能表現測量對於門診慢性疾病老人衰弱與失能起伏之預測分析 | zh_TW |
dc.title | Physical Performance-based Measurements as Predictors of Frailty and Disability Transition in Clients of Geriatric Clinics | en |
dc.type | Thesis | |
dc.date.schoolyear | 100-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 陳慶餘(Ching-Yu Chen),王靜怡(Ching-Yi Wang) | |
dc.subject.keyword | 衰弱,失能,體能表現,預測,起伏, | zh_TW |
dc.subject.keyword | frailty,disability,physical performance,prediction,transition, | en |
dc.relation.page | 139 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2012-08-20 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 物理治療學研究所 | zh_TW |
顯示於系所單位: | 物理治療學系所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-101-1.pdf 目前未授權公開取用 | 4.12 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。