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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 顏家鈺(Jia-Yush Yen) | |
| dc.contributor.author | Che-Jung Hsu | en |
| dc.contributor.author | 許哲榮 | zh_TW |
| dc.date.accessioned | 2021-06-16T13:24:47Z | - |
| dc.date.available | 2016-07-30 | |
| dc.date.copyright | 2013-07-30 | |
| dc.date.issued | 2013 | |
| dc.date.submitted | 2013-07-23 | |
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Chapelon, “Testing of a HIFU probe for the treatment of superficial venous insufficiency by using MRI”, In Engineering in Medicine and Biology Society, 28th Annual International Conference of the IEEE, 3533-3536, 2006. [16] J. A. Bargoshadi, and E. Najafiaghdam, “Ultrasonic dispersion system design and optimization using multiple transducers”, In Piezoelectricity, Acoustic Waves, and Device Applications (SPAWDA) and 2009 China Symposium on Frequency Control Technology, Joint Conference of the 2009 Symposium on, 96-96, 2009. [17] S. D. Paolis, F. Lionetto, and A. Maffezzoli, “Finite Element Modeling of Ultrasonic Transducers for Polymer Characterization”, Excerpt from the Proceedings of the COMSOL Conference, 3, 4, 2009. [18] R. Lerch, “Simulation of piezoelectric devices by two-and three-dimensional finite elements”, Ultrasonics, Ferroelectrics and Frequency Control, IEEE Transactions on, 37(3), 233-247, 1990. [19] Y. Kagawa, and T. 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Pennes, “Analysis of tissue and arterial blood temperatures in the resting human forearm”, Journal of applied physiology, 1(2), 93-122, 1948. [29] J. Koo, and C. Kleinstreuer, “Viscous dissipation effects in microtubes and microchannels”, International journal of heat and mass transfer, 47(14), 3159-3169, 2004. [30] H. L. Liu, H. Chang, W. S. Chen, T. C. Shih, J. K. Hsiao, and W. L. Lin, “Feasibility of transrib focused ultrasound thermal ablation for liver tumors using a spherically curved 2D array: A numerical study”, Medical physics, 34, 3436, 2007. [31] S. W. Huang, and P. C. Li, “Ultrasonic computed tomography reconstruction of the attenuation coefficient using a linear array”, Ultrasonics, Ferroelectrics and Frequency Control, IEEE Transactions on, 52(11), 2011-2022, 2005. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/62044 | - |
| dc.description.abstract | HIFU (High Intensity Focused Ultrasound)手術為腫瘤患者提供一種較少副作用的療程，HIFU療程可適用燒灼在多種類型的腫瘤上並已有許多治療成功的案例，近年來HIFU手術開始嘗試治療更棘手的腫瘤，此類型的腫瘤許多都埋藏在肋骨後方，肋骨會阻擋並吸收原本應該進入腫瘤的超音波能量造成治療效果降低並有肋骨過熱壞死的風險，本論文藉由消音器原理設計直接在肋骨前方貼附於表皮上的特殊聲學結構，將聲能在進入肋骨之前先行困在結構內並消耗殆盡，同時達到保護肋骨與超音波探頭的目標，本論文將陳述特殊聲學結構的原理與設計準則，並利用模擬與實驗同步驗證特殊聲學結構設計的成效。 | zh_TW |
| dc.description.abstract | HIFU (High Intensity Focused Ultrasound) offers conservative malignant tumor treatment with very little side effects. The uses of HIFU in medical treatment for malignant tumor have excited many research interests. Its applications range over the treatment of various types of tumors, and there have been many reports on successful treatments. More recent researches on HIFU therapy have started to look into some difficulties to treat tumors. The most encountered situations are the tumors that are hidden behind the rib cage. The ribs both blocked and absorbed the HIFU energy, rendering the treatment ineffective while cause pain to the patient. This thesis explores ways for rib sparing HIFU technology. Instead of the straight forward blocking by sound absorbing material, this thesis looks into the application of muffler theorem and design sound reflecting or sound annihilation channels to redirect the ultrasound energy. It is believed that the sound channel is a more energy-efficient way of rib sparing. The thesis provides both the theoretical development and the design guidelines for the sound annihilation channels. The thesis also provides experimental verifications to show that the approach is in fact effective and is easy to implement. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-16T13:24:47Z (GMT). No. of bitstreams: 1 ntu-102-R00522807-1.pdf: 15875581 bytes, checksum: a3c4f6b49e966089ef3528c2d85ab354 (MD5) Previous issue date: 2013 | en |
| dc.description.tableofcontents | 中文摘要 i
Abstract iii Contents v List of Figure ix List of Table xiii Glossary of Symbols xv Chapter 1 Introduction...1 1.1 Motivation...1 1.2 Evolution and Challenge of HIFU Surgery...2 1.3 Goals of This Thesis...6 1.4 Thesis Structure and Contribution...9 Chapter 2 Muffler Structure Theorem and Design...11 2.1 Type of Muffler...11 2.1.1 Reactive Muffler...11 2.1.2 Dissipative Muffler ...12 2.2 Muffler Performance Indicators...13 2.2.1 Transmission Loss (TL)...13 2.2.2 Insertion Loss (IL)...13 2.2.3 Noise Reduction (NR)...13 2.3 Electro-Mechano-Acoustical Analogies...14 2.4 Helmholtz Resonator...19 2.4.1 General Helmholtz Resonator Impedance...19 2.4.2 Traditional Helmholtz Resonator analysis...22 2.4.3 Helmholtz Resonator Impedance in Small Wave Length...24 2.5 Transfer Matrix Method...26 2.5.1 Duct...28 2.5.2 Area Discontinuity...29 2.5.3 Side Branch...30 2.6 Special Acoustic Blocking Structure Design...31 2.6.1 Size Decision of Acoustic Blocking Structure...32 2.6.2 Resonant Frequency and Vibration Mode Calculation...34 2.6.3 Transfer Matrix Representation of Designed Structure...36 2.6.4 Transmission Loss Calculated by Transfer Matrix...37 Chapter 3 HIFU Simulation Verification...41 3.1 Governing Equation of Acoustic Wave...41 3.2 Bioheat Transfer Theory...43 3.3 Simulation Framework and Parameters...45 3.4 Simulation Results...49 3.4.1 HIFU Ablation without Ribs Protection...49 3.4.2 HIFU Ablation with Baffle Protection...52 3.4.3 HIFU Ablation with Perforated PU Foam Protection...55 3.4.4 HIFU Ablation with Acoustic Blocking Structure Protection...58 3.5 Summary...63 Chapter 4 HIFU Experiment Verification...65 4.1 Equipment Specification...65 4.1.1 Phantom...65 4.1.2 Transducer...66 4.1.3 RF Generator...67 4.1.4 Thermocouple Module ...68 4.2 Experiment Arrangement...68 4.3 Experiment Result...71 4.3.1 HIFU Ablation without Rib Protection...72 4.3.2 HIFU Ablation with Baffle Protection...74 4.3.3 HIFU Ablation with Perforated PU Foam Protection...75 4.3.4 HIFU Ablation with Acoustic Blocking Structure Protection...77 4.4 Summary...79 Chapter 5 Conclusion...81 References...83 | |
| dc.language.iso | en | |
| dc.subject | 聲機電類比 | zh_TW |
| dc.subject | 消音器 | zh_TW |
| dc.subject | HIFU手術 | zh_TW |
| dc.subject | Pennes方程式 | zh_TW |
| dc.subject | 轉移矩陣分析法 | zh_TW |
| dc.subject | 赫姆霍茲共鳴器 | zh_TW |
| dc.subject | Muffler | en |
| dc.subject | Electro-mechano-acoustical analogy | en |
| dc.subject | Helmholtz resonator | en |
| dc.subject | Transfer matrix method | en |
| dc.subject | Pennes equation | en |
| dc.subject | HIFU therapy | en |
| dc.title | 應用於HIFU手術肋骨保護之聲學設計 | zh_TW |
| dc.title | The Acoustic Design for Rib Sparing HIFU Surgery | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 101-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳永耀(Yung-Yao Chen),連豊力(Li-Li Lien),何明志(Ming-Chih He) | |
| dc.subject.keyword | 消音器,HIFU手術,Pennes方程式,轉移矩陣分析法,赫姆霍茲共鳴器,聲機電類比, | zh_TW |
| dc.subject.keyword | Muffler,HIFU therapy,Pennes equation,Transfer matrix method,Helmholtz resonator,Electro-mechano-acoustical analogy, | en |
| dc.relation.page | 86 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2013-07-24 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
| 顯示於系所單位： | 機械工程學系 | |
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