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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 楊志忠(Chih-Chung Yang) | |
dc.contributor.author | Hung-Yu Tseng | en |
dc.contributor.author | 曾虹諭 | zh_TW |
dc.date.accessioned | 2021-06-16T13:17:47Z | - |
dc.date.available | 2013-07-30 | |
dc.date.copyright | 2013-07-30 | |
dc.date.issued | 2013 | |
dc.date.submitted | 2013-07-29 | |
dc.identifier.citation | [1.1] K. L. Kelly et al., J. Phys. Chem. B 107, 668 (2003).
[1.2] C. F. Bohren and D. R. Huffman, ' Absorption and Scattering of Light by Small Particles', John Wiley & Sons, Inc., New York, NY, 1st edition (1983). [1.3] M. C. Daniel and D. Astruc, Chem. Rev. 104, 293 (2004). [1.4] M. Eghtedari, A. V. Liopo, J. A. Copland, A. A. Oraevsky and M. Motamedi, Nano Lett. 9, 287 (2009). [1.5] W. I. Choi, J. Y. Kim, C. Kang, C. C. Byeon, Y. H. Kim, and G. Tae, ACS Nano 5, 1995 (2011). [1.6] G. von Maltzahn, J. H. Park, A. Agrawal, N. K. Bandaru, S. K. Das, M. J. Sailor, and S. N. Bhatia, Cancer Res. 69, 3892 (2009). [1.7] A. M. Gobin, J. J. Moon, and J. L. West, Internal. J. Nanomed. 3, 351 (2008). [1.8] A. M. Gobin, M. H. Lee, N. J. Halas, W. D. James, R. A. Drezek, and J. L. West, Nano Lett. 7, 1929 (2007). [1.9] L. B. Carpin, L. R. Bickford, G.Agollah, T. K. Yu, R. Schiff, Y. Li, and R. A. Drezek, Breast Cancer Res. Treat. 125, 27 (2011). [1.10] A. M. Schwartzberg, T. Y. Olson, C. E. Talley, and J. Z. Zhang, J. Phys. Chem. B 110, 19935 (2006). [1.11] J. Z. Zhang, J. Phys. Chem. Lett. 1, 686 (2010). [1.12] J. Chen, D. Wang, J. Xi, L. Au, A. Siekkinen, A. Warsen, Z. Y. Li, H. Zhang, Y. Xia, and X. Li, Nano Lett. 7, 1318 (2007). [1.13] J. Chen, F. Saeki, B. J. Wiley, H. Cang, M. J. Cobb, Z. Y. Li, L. Au, H. Zhang, M. B. Kimmey, X. Li, and Y. Xia, Nano Lett. 5, 473 (2005). [1.14] J. Chen, C. Glaus, R. Laforest, Q. Zhang, M. Yang, M. Gidding, M. J. Welch, and Y. Xia, Small 6, 811 (2010). [1.15] M. E. Brezinski, G. J. Tearney, B. E. Bouma, J. A. Izatt, M. R. Hee, E. A. Swanson, J. F. Southern, and J. G. Fujimoto, Circulation 93, 1206 (1996). [1.16] J. Turkevitch, P. C. Stevenson and J. Hillier, Discuss. Faraday Soc. 11, 55 (1951). [1.17] G. Schmid, R. Pfeil, R. Boese, F. Bandermann, S. Meyer, G. H. M. Calis and J. W. A. van der Velden, Chem. Ber. 114, 3634 (1981). [1.18] M. Brust, M. Walker, D. Bethell, D. J. Schiffrin and R. Whyman, J. Chem. Soc., Chem. Commun. 801 (1994). [1.20] M. J. Hostetler, J. E. Wingate, C. J. Zhong, J. E. Harris, R. W. Vachet, M. R. Clark, J. D. Londono, S. J. Green, J. J. Stokes, G. D. Wignall, G. L. Glish, M. D. Porter, N. D. Evans and R. W. Murray, Langmuir 14, 17 (1998). [1.21] N. R. Jana, L. Gearheart and C. J. Murphy, Chem. Mater. 13, 2313 (2001). [1.22] S. Link, M. A. El-Sayed J. Phys. Chem. B 103 4212-4217 (1999). [1.23] U. Kreibig and M. Vollmer, Optical Properties of Metal Clusters, Springer, Berlin (1995). [1.24] R. Gans, Ann. Phys. 37, 881 (1912). [1.25] F. Kim, J. H. Song and P. D. Yang, J. Am. Chem. Soc. 124, 14316 (2002). [1.26] C. R. Martin, Chem. Mater. 8, 1739 (1996). [1.27] S. S. Chang, C. W. Shih, C. D. Chen, W. C. Lai and C. R. C. Wang, Langmuir 15, 701 (1999). [1.28] C. J. Murphy, T. K. Sau, A. M. Gole, C. J. Orendorff, J. X. Gao, L. F. Gou, S. E. Hunyadi and T. Li, J. Phys. Chem. B 109, 13857 (2005) and references therein. [1.29] Professor Chung-Yuan Mou, Department of Chemistry, National Taiwan University. [1.30] B. Nikoobakht, M. A. El-Sayed Chem. Mater. 15 1957-1962 (2003). [1.31] A. E. Neeves and M. H. Birnboim, J. Opt. Soc. Am. B 6, 787 (1989). [1.32] R. D. Averitt, D. Sarkar and N. J. Halas, Phys. Rev. Lett. 78, 4217 (1997). [1.33] C. Loo, A. Lin, L. Hirsch, M. H. Lee, J. Barton, N. Halas, J. West and R. Drezek, Technology in Cancer Research & Treatment 3 1 1533-0346 (2004). [1.34] H. P. Liang, L. J. Wan, C. L. Bai and L. Jiang, J. Phys. Chem. B 109, 7795 (2005). [1.35] Y. Sun and Y. Xia, Science 298, 2176 (2002). [1.36] S. E. Skrabalak, J. Chen, Y. Sun, X. Lu, L. Au, C. M. Cobley and Y. Xia, ACCOUNTS OF CHEMICAL RESEARCH 41 12 1587-1595 (2008). [1.37] J. Aizpurua, P. Hanarp, D. S. Sutherland, M. Ka‥ll, G. W. Bryant, and F. J. Garc?’a de Abajo, Phys. Rev. Lett. 90, 057401 (2003). [1.38] F. Hao, E. M. Larsson, T. A. Ali, D. S. Sutherland and P. Nordlander, Chem. Phys. Lett. 458 262 (2008). [1.39] E. M. Larsson, J. Alegret, M. K‥all and D. S. Sutherland, Nano Lett. 7 1256 (2007). [1.40] H. Y. Tseng, C. K. Lee, S. Y. Wu, T. T. Chi, K. M. Yang, J. Y. Wang, Y. W. Kiang, C. C. Yang, M. T. Tsai, Y. C. Wu, H. Y. E. Chou, and C. P. Chiang, Nanotechnology 21, 295102 (2010). [1.41] C. K. Lee, H. Y. Tseng, C. Y. Lee, S. Y. Wu, T. T. Chi, K. M. Yang, H. Y. E. Chou, M. T. Tsai, J. Y. Wang, Y. W. Kiang, C. P. Chiang, and C. C. Yang, Biomed. Opt. Express 1, 1060-1074 (2010). [1.42] H. Y. Tseng, W. F. Chen, Y. W. Kiang, and C. C. Yang, Nanotechnology 24, 065102 (2013). [1.43] S. Y. Wu, W. M. Chang, H. Y. Tseng, C. K. Lee, T. T. Chi, J. Y. Wang, Y. W. Kiang, and C. C. Yang, Plasmonics 6, 547-555 (2011). [1.44] H. G. Liu et al. Colloids and Surfaces A: Physicochem. Eng. Aspects 312 203–208 (2008). [1.45] Y. Hu et al. Proc. of SPIE Vol. 8595 85950B-1-7 (2013). [1.46] D. Huang, E. A. Swanson, C. P. Lin. J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991). [1.47] A. M. Rollins, M. D. Kulkarni, S. Yazdanfar, R. Ung-arunyawee, and J. A. Izatt, Opt. Express 3, 219 (1998). [1.48] A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Comm. 117, 43 (1995). [1.49] G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998). [1.50] J. F. Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, Opt. Lett. 28, 2067 (2003). [1.51] M. A. Choma, M. V. Sarunic, C. Yang, and J. Izatt, Opt. Express 11, 2183 (2003). [1.52] R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, Opt. Express 11, 889 (2003). [1.53] M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, Opt. Lett. 27, 1415 (2002). [1.54] B. Golubovic, B. E. Bouma, G. J. Tearney, and J. G. Fujimoto, Opt. Lett. 22, 1704 (1997). [1.55] S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, Opt. Lett. 22, 340 (1997). [1.56] S. H. Yun, G. J. Tearney, J. F. Boer, and B. E. Bouma, Opt. Express 12, 2977 (2004). [1.57] J. Zhang, J. S. Nelson, and Z. Chen, Opt. Lett. 30, 1 (2005). [1.58] M. Marsh and H. T. McMahon, Science 285, 215 (1999). [1.59] S. Mukherjee, R. N. Ghosh, and F. R. Maxfifld, Physiolog. Rev. 77, 760 (1997). [1.60] A. Albanese, P. S. Tang, and W. C.W. Chan, Annu. Rev. Biomed. Eng. 14, 1 (2012). [1.61] B. D. Chithrani and W. C. W. Chan, Nano Lett. 7, 1542 (2007). [1.62] F. Lu, S. H. Wu, Y. Hung, and C. Y. Mou. Small 5, 1408 (2009). [1.63] H. Jin, D. A. Heller, R. Sharma, and M. S. Strano. ACS Nano 3, 149 (2009). [1.64] S. E. Gratton, P. A. Ropp, P. D. Pohlhaus, J. C. Luft, and V.J. Madden, Proc. Natl. Acad. Sci. USA. 105, 11613 (2008). [1.65] A. G. Kanaras, D. Bartczak, T. Sanchez-Elsner, F. Louafi, and T. M. Millar, Small 7, 388 (2011). [1.66] S. Muro, C. Garnacho, J. A. Champion, J. Leferovich, and C. Gajewski, Mol. Ther. 16, 1450 (2008). [1.67] D. L. J. Thorek and A. Tsourkas, Biomaterials 29, 3583 (2008). [1.68] I. Slowing, B. G. Trewyn, and V. S. Y. Lin, J. Am. Chem. Soc. 128, 14792 (2006). [1.69] J. Wang, S. Tian, R. A. Petros, M. E. Napier, and J. M. Desimone, J. Am. Chem. Soc. 132, 11306 (2010). [1.70] M. B. Jr, M. Moronne, P. Gin, S. Weiss, and A. P. Alivisatos, Science 25, 2013 (1998). [1.71] C. Yang, M. A. Choma, L. E. Lamb, J. D. Simon, and J. A. Izatt, Opt. Lett. 29, 1396 (2004). [1.72] P. Fortina, L. J. Kricka, D. J. Graves, J. Park, T. Hyslop, F. Tam, N. Halas, S. Surrey, and S. A. Waldman, Trends in Biotechnology 25, 145 (2007). [1.73] A. Neely, C. Perry, B. Varisli, A. K. Singh, T. Arbneshi, D. Senapati, J. R. Kalluri, and P. C. Ray, ACS Nano. 3, 2834 (2009). [1.74] N. Iftimia, A. K. Iyer, D. X. Hammer, N. Lue, M. Mujat, M. Pitman, R. D. Ferguson, and M. Amiji, Opt. Express 3, 178 (2011). [1.75] A. S. Thakor, J. Jokerst, C. Zavaleta, T. F. Massoud, and S. S. Gambhir, Nano Lett. 11, 4029 (2011). [1.76] J. V. Jokerst, A. J. Cole, D. V. D. Sompel, and S. S. Gambhir, ACS Nano 6, 10366 (2012). [1.77] M. Wang, C. Wang, K. L. Young, L. Hao, M. Medved, T. Rajh, H. C. Fry, L. Zhu, G. S. Karczmar, C. Watson, J. S. Jiang, N. M. Markovic, and V. R. Stamenkovic, Chem. Mater. 24, 2423 (2012). [1.78] B. Y. S. Kim, W. Jiang, J. Oreopoulos, C. M. Yip, J. T. Rutka, and W. C. W. Chan, Nano Lett. 8, 3887 (2008). [1.79] D. J. Vugts, A. Vervoort, M. Walsum, G. W. M. Visser, M. S. Robillard, R. M. Versteegen, R. C. M. Vulders, J. D. M. Herscheid, and G. A. M. Dongen, Bioconjugate Chem. 10, 2072 (2011). [1.80] E. Poselt, C. Schmidtke, S. Fischer, K. Peldschus, J. Salamon, H. Kloust, H. Tran, A. Pietsch, M. Heine, G. Adam, U. Schumacher, C. Wagener, S. Forster, and H. Weller, ACS Nano 12, 3346 (2012). [1.81] C. J. Murphy, A. M. Gole, J. W. Stone, P. N. Sisco, A. M. Alkilany, E. C. Goldsmith, and S. C. Baxter, Acc. Chem. Res. 41, 1721 (2008). [1.82] N. R. Jana, L. Gearheart, and C. J. Murphy, Langmuir 17, 6782 (2001). [1.83] B. V. D. Broek, N. Devoogdt, A. D’Hollander, H. L. Gijs, K. Jans, L. Lagae, S. Muyldermans, G. Maes, and G. Borghs, ACS Nano 17, 4319 (2011). [1.84] S. Basiruddin, A. R. Maity, A. Saha, and N. R. Jana, J. Phys. Chem. C 115, 19612 (2011). [1.85] C. Yu, H. Nakshatri, and J. Irudayaraj, Nano Lett. 7, 2300 (2007). [1.86] N. Lozano, W. T. A. Jamal, A. Taruttis, N. Beziere, N. C. Burton, J. V. D. Bossche, M. Mazza, E. Herzog, V. Ntziachristos, and K. Kostarelos, J. Am. Chem. Soc. 134, 13256 (2012). [1.87] L. Seveus, M. Vaisala, S. Syrjanen, M. Sandberg, A. Kuusisto, R. Harju, J. Salo, I. Hemmila, H. Kojola, and E. Soini, Cytometry 13, 329 (1992). [1.88] J. L. Kovar, M. A. Simpson, A. S. Geschwender, and D. M. Olive, Analytical Biochemistry 367, 1 (2007). [1.89] S. Tyagi and F. R. Kramer, Nature Biotechnology 14, 303 (1996). [1.90] S. Achilefu, R. B. Dorshow, J. E. Bugaj, and R. Rajagopalan, Invest Radiol 35, 479 (2000). [1.91] V. Ntziachristos, E. A. Schellenberger, J. Ripoll, D. Yessayan, E. Graves, A. Bogdanov, L. Josephson, and R. Weissleder, Proc. Natl. Acad. Sci. USA. 101, 12294 (2004). [1.92] G. Kostenich, N. Livnah, T. A. Bonasera, T. Yechezkel, Y. Salitra, P. Litman, S. Kimel, and A. Orenstein, Lung Cancer 50, 319 (2005). [1.93] E. M. Judd, K. R. Ryan, W. E. Moerner, L. Shapiro, and H. H. McAdams, Proc. Natl. Acad. Sci. USA. 100, 8235 (2003). [1.94] P. Mitchell, Nature Biotechnology 19, 1013 (2001). [1.95] K. T. Yong, Y. Wang, I. Roy, H. Rui, M. T. Swihart, W. C. Law, S. K. Kwak, L. Ye, J. Liu, S. D. Mahajan, and J. L. Reynolds, Theranostics 2, 681 (2012). [1.96] F. Chen and D. Gerion, Nano Lett. 4, 1827 (2004). [1.97] H. Mattoussi, G. Palui, and H. B. Na, Biological Interactions of Nanoparticles 64, 138 (2012). [1.98] E. V. Zagaynova, M. V. Shirmanova, M. Y. Kirillin, B. N. Khlebtsov, A. G. Orlova, I. V. Balalaeva, M. A. Sirotkina, M. L. Bugrova, P. D. Agrba, and V. A. Kamensky, “Contrasting properties of gold nanoparticles for optical coherence tomography: phantom, in vivo studies and Monte Carlo simulation,” Phys. Med. Biol. 53, 4995-5009 (2008). [1.99] A. M. Gobin, M. H. Lee, N. J. Halas, W. D. James, R. A. Drezek, and J. L. West, “Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy,” Nano Lett. 7, 1929-1934 (2007). [1.100] C. S. Kim, P. Wilder-Smith, Y. C. Ahn, L. H. L. Liaw, Z. Chen, and Y. J. Kwon, “Enhanced detection of early-stage oral cancer in vivo by optical coherence tomography using multimodal delivery of gold nanoparticles,” J. Biomed. Opt. 14, 034008 (2009). [1.101] J. H. Baek, T. Krasieva, S. Tang, Y. Ahn, C. S. Kim, D. Vu, Z. Chen, and P. Wilder-Smith, “Optical approach to the salivary pellicle,” J. Biomed. Opt. 14, 044001 (2009). [1.102] M. Kirillin, M. Shirmanova, M. Sirotkina, M. Bugrova, B. Khlebtsov, and E. Zagaynova, “Contrasting properties of gold nanoshells and titanium dioxide nanoparticles for optical coherence tomography imaging of skin: Monte Carlo simulations,” J. Biomed. Opt. 14, 021017 (2009). [1.103] J. Chen, F. Saeki, B. J. Wiley, H. Cang, M. J. Cobb, Z. Y. Li, L. Au, H. Zhang, M. B. Kimmey, X. Li, and Y. Xia, “Gold nanocages: Bioconjugation and their potential use as optical imaging contrast agents,” Nano Lett. 5, 473-477 (2005). [1.104] D. C. Adler, S. W. Huang, R. Huber, and J. G. Fujimoto, “Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography,” Opt. Express 16, 4376-4393 (2008). [1.105] C. Zhou, T. H. Tsai, D. C. Adler, H. C. Lee, D. W. Cohen, A. Mondelblatt, Y. Wang, J. L. Connolly, and J. G. Fujimoto, “Photothermal optical coherence tomography in ex vivo human breast tissues using gold nanoshells,” Opt. Lett. 35, 700-702 (2010). [1.106] M. C. Skala, M. J. Crow, A. Wax, and J. A. Izatt, “Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres,” Nano Lett. 8, 3461–3467 (2008). [1.107] H. Cang, T. Sun, Z. Y. Li, J. Chen, B. J. Wiley, Y. Xia, and X. Li, “Gold nanocages as contrast agents for spectroscopic optical coherence tomography,” Opt. Lett. 30, 3048-3050 (2005). [1.108] X. Huang and M. A. El-Sayed, J. Adv. Res. 1, 13 (2010). [1.109] B. Jang, J. Y. Park, C. H. Tung, I. H. Kim, and Y. Choi, ACS Nano 5, 1086 (2011). [1.110] X. Huang, I. H. El-Sayed, W. Qianand, and M. A. El-Sayed, J. Am. Chem. Soc. 128, 2115 (2006). [1.111] S. Lal, S. E. Clareand, and N. J. Halas, Acc. Chem. Res. 41, 1842 (2008). [1.112] S. Jelveh and D. B. Chithrani, Cancers 3, 1081 (2011). [1.113] E. S. Day, J. G. Morton, and J. L. West, J. Biomech. Eng. 131, 074001 (2009). [1.114] X. Huang, P. K. Jain, I. H. El-Sayed, and M. A. El-Sayed, Photochem Photobiol. 82, 412 (2006). [1.115] R. J. Bernardi, A. R. Lowery, P. A. Thompson, S. M. Blaney, and J. L. West, J. Neurooncol. 86, 165 (2008). [1.116] R. Chen, X. Zheng, H. Qian, X. Wang, J. Wang, and X. Jiang, Biomater. Sci. DOI: 10.1039/C2BM00138A (2013). [1.117] H. Liu, D. Chen, L. Li, T. Liu, L. Tan, X. Wu, and F. Tang, Angew Chem Int Ed Engl. 50, 891 (2011). [1.118] S. Link and M. A. El-Sayed, J. Phys. Chem. B 103, 42127 (1999). [1.119] M. E. Brezinski, G. J. Tearney, B. E. Bouma, J. A. Izatt, M. R. Hee, E. A. Swanson, J. F. Southern, and J. G. Fujimoto, Circulation 93, 1206 (1996). [1.120] L. R. Hirsch, R. J. Stafford, J. A. Bankson, S. R. Sershen, B. Rivera, R. E. Price, J. D. Hazle, N. J. Halas, and J. L. West, PNAS 100, 13549 (2003). [1.121] B. Jang, J. Y. Park, C. H. Tung, I. H. Kim, and Y. Choi, “Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo,” ACS Nano 5, 1086-1094 (2011). [1.122] J. M. Tucker-Schwartz, T. A. Meyer, C. A. Patil, C. L. Duvall, and M. C. Skala, Biomed. Opt. Express 3, 2881 (2012). [1.123] I. H. El-Sayed, X. Huang and M. A. El-Sayed, Nano Lett. 5 829 (2005). [1.124] H. Ding, K. T. Yong, I. Roy, H. E. Pudavar, W. C. Law, E. J. Bergey and P. N. Prasad, J. Phys. Chem. 111 12552 (2007). [1.125] P. K. Jain, X. Huang, I. H. El-Sayed and M. A. El-Sayed, Acc. Chem. Res. 41 1578 (2008). [1.126] K. Kneipp, H. Kneipp and J. Kneipp, Acc. Chem. Res. 39 443 (2006). [1.127] S. Kuhn, U. Hakanson, L. Rogobete and V. Sandoghdar, Phys. Rev. Lett. 97 017402 (2006). [1.128] M. V. Yigit and Z. Medarova, Am. J. Nucl. Med. Mol. Imag. 2 232 (2012). [1.129] Y, Cheng, A. C. Samia, J. D. Meyers, I. Panagopoulos, B. Fei and C. J. Burda, Am. Chem. Soc. 130 10643 (2008). [1.130] P. Shi, K. Qu, J. Wang, M. Li, J. Ren and X. Qu, Chem. Commun. 48 7640 (2012). [1.131] G. F. Paciotti, D. G. I. Kingston and L. Tamarkin, Drug. Develop. Res. 67 47 (2006). [1.132] M. S. Yavuz, Y. Cheng, J. Chen, C. M. Cobley, Q. Zhang, M. Rycenga, J. Xie, C. Kim, K. H. Song, A. G. Schwartz, L. V. Wang and Y. Xia, Nature Mat. 8 935 (2009). [1.133] T. A. Kelf, Y. Tanaka, O. Matsuda, E. M. Larsson, D. S. Sutherland and O. B. Wright, Nano Lett. 11 3893 (2011). [2.1] A. Neogi, C. W. Lee, H. O. Everitt, T. Kuroda, A. Tackeuchi, and E. Yablonvitch, Phys. Rev. B. 66, 153305 (2002). [2.2] G. Sun, J. B. Khurgin, and R. A. Soref, Appl. Phys. Lett. 90, 111107 (2007). [2.3] D. M. Yeh, C. F. Huang, C. Y. Chen, Y. C. Lu, and C. C. Yang, Nanotechnology 19, 345201 (2008). [2.4] V. E. Ferry, L. A. Sweatlock, D. Pacifici, and H. A. Atwater, Nano Lett. 8, 4391-4397 (2008). [2.5] C. Rockstuhla and F. Lederer, Appl. Phys. Lett. 94, 213102 (2009). [2.6] I. H. El-Sayed, X. Huang, and M. A. El-Sayed, Nano Lett. 5, 829-834 (2005). [2.7] H. Ding, K. T. Yong, I. Roy, H. E. Pudavar, W. C. Law, E. J. Bergey, and P. N. Prasad, J. Phys. Chem. C 111, 12552-12557 (2007). [2.8] E. V. Zagaynova, M. V. Shirmanova, M. Y. Kirillin, B. N. Khlebtsov, A. G. Orlova, I. V. Balalaeva, M. A. Sirotkina, M. L. Bugrova, P. D. Agrba, and V. A. Kamensky, Phys. Med. Biol. 53, 4995–5009 (2008). [2.9] P. K. Jain, X. Huang, I. H. El-Sayed, and M. A. El-Sayed, Accounts of Chemical Research 41 1578-1586 (2008). [2.10] A. L. Oldenburg, M. N. Hansen, T. S. Ralston, A. Wei, and S. A. Boppart, J. Mater. Chem. 19, 6407–6411 (2009). [2.11] X. Huang, P. K. Jain, I. H. El-Sayed, M. A. El-Sayed, Lasers Med Sci 23, 217–228 (2008). [2.12] J. L. Li, D. Day, and M. Gu, Adv. Mater. 20, 3866–3871 (2008). [2.13] X. Huang, I. H. El-Sayed, W. Qian, and M. A. El-Sayed, J. Am. Chem. Soc. 128, 2115-2120 (2006). [2.14] S. Lal, S. E. Clare, and N. J. Halas, Accounts Chem. Res. 41, 1842-1851 (2008). [2.15] M. Eghtedari, A. V. Liopo, J. A. Copland, A. A. Oraevsky, and M. Motamedi, Nano Lett. 9, 287-291 (2009). [2.16] T. S. Troutman, J. K. Barton, and M. Romanowski, Optics Lett. 32, 1438-1440 (2007). [2.17] G. von Maltzahn, J. H. Park, A. Agrawal, N. K. Bandaru, S. K. Das, M. J. Sailor, and S. N. Bhatia, Cancer Res. 69, 3892-3900 (2009). [2.18] A. M Gobin, J. J Moon, J. L West, International J. Nanomedicine 3, 351-358 (2008). [2.19] A. M. Gobin, M. H. Lee, N. J. Halas, W. D. James, R. A. Drezek, and J. L. West, Nano Lett. 7, 1929-1934 (2007). [2.20] H. Liu, D. Chen, F. Tang, G. Du, L. Li, X. Meng, W. Liang, Y. Zhang, X. Teng, and Y. Li, Nanotechnology 19, 455101 (2008). [2.21] J. Chen, D. Wang, J. Xi, L. Au, A. Siekkinen, A. Warsen, Z. Y. Li, H. Zhang, Y. Xia, and X. Li, Nano Lett. 7, 1318-1322 (2007). [2.22] J. Chen, F. Saeki, B. J. Wiley, H. Cang, M. J. Cobb, Z. Y. Li, L. Au, H. Zhang, M. B. Kimmey, X. Li, and Y. Xia, Nano Lett. 5, 473-477 (2005). [2.23] L. Au, D. Zheng, F. Zhou, Z. Y. Li, X. Li, and Y. Xia, ACS Nano 2, 1645–1652 (2008). [2.24] E. M. Larsson, J. Alegret, M. Ka1ll, and D. S. Sutherland, Nano Lett. 7, 1256-1263 (2007). [2.25] F. Hao, E. M. Larsson, T. A. Ali, D. S. Sutherland, and P. Nordlander, Chem. Phys. Lett. 458, 262–266 (2008). [2.26] J. Aizpurua, P. Hanarp, D. S. Sutherland, M. Ka‥ll, G. W. Bryant, and F. J. Garc?’a de Abajo, Phys. Rev. Lett. 90, 057401 (2003). [2.27] D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991). [2.28] J. G. Fujimoto, M. E. Brezinski, G. T. Tearney, S. A. Boppart, B. E. Bouma, M. R. Hee, J. F. Southern, and E. A. Swanson, Nat. Med. (N.Y.) 1, 970 (1995). [2.29] D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, Nature Photon. 1, 709 (2007). [2.30] M. T. Tsai, H. C. Lee, C. K. Lee, C. H. Yu, H. M. Chen, C. P. Chiang, C. C. Chang, Y. M. Wang, and C. C. Yang, Optics Express 16, 15847 (2008). [2.31] C. K. Lee, M. T. Tsai, H. C. Lee, Y. M. Wang, H. M. Chen, C. P. Chiang, and C. C. Yang, J. Biomed. Opt. 14, 054008 (2009). [2.32] M. T. Tsai, C. K. Lee, H. C. Lee, H. M. Chen, C. P. Chiang, Y. M. Wang, and C. C. Yang, J. Biomed. Opt. 14, 044028 (2009). [2.33] P. Hanarp, D. S. Sutherland, J. Gold, and B. Kasemo, Colloids and Surfaces A: Physicochem. Eng., Aspects 214, 23-36 (2003). [2.34] E. D. Palik, Handbook of Optical Constants of Solids (Academic Press, Boston, 1991). [2.35] A. V. Belikov, K. V. Prikhod'ko, O. A. Smolyanskaya, and V. A. Protasov, J. Opt. Technol. 70, 811-814 (2003). [3.1] I. H. El-Sayed, X. Huang and M. A. El-Sayed, Nano Lett. 5 829 (2005). [3.2] H. Ding, K. T. Yong, I. Roy, H. E. Pudavar, W. C. Law, E. J. Bergey and P. N. Prasad, J. Phys. Chem. 111 12552 (2007). [3.3] E. V. Zagaynova, M. V. Shirmanova, M. Y. Kirillin, B. N. Khlebtsov, A. G. Orlova, I. V. Balalaeva, M. A. Sirotkina, M. L. Bugrova, P. D. Agrba and V. A. Kamensky, Phys. Med. Biol. 53 4995 (2008). [3.4] P. K. Jain, X. Huang, I. H. El-Sayed and M. A. El-Sayed, Acc. Chem. Res. 41 1578 (2008). [3.5] H. Y. Tseng, C. K. Lee, S. Y. Wu, T. T. Chi, K. M. Yang, J. Y. Wang, Y. W. Kiang, C. C. Yang, M. T. Tsai, Y. C. Wu, H. Y. E. Chou and C. P. Chiang, Nanotechnology 21 295102 (2010). [3.6] K. Kneipp, H. Kneipp and J. Kneipp, Acc. Chem. Res. 39 443 (2006). [3.7] S. Kuhn, U. Hakanson, L. Rogobete and V. Sandoghdar, Phys. Rev. Lett. 97 017402 (2006). [3.8] M. V. Yigit and Z. Medarova, Am. J. Nucl. Med. Mol. Imag. 2 232 (2012). [3.9] Y, Cheng, A. C. Samia, J. D. Meyers, I. Panagopoulos, B. Fei and C. J. Burda, Am. Chem. Soc. 130 10643 (2008). [3.10] P. Shi, K. Qu, J. Wang, M. Li, J. Ren and X. Qu, Chem. Commun. 48 7640 (2012). [3.11] G. F. Paciotti, D. G. I. Kingston and L. Tamarkin, Drug. Develop. Res. 67 47 (2006). [3.12] M. S. Yavuz, Y. Cheng, J. Chen, C. M. Cobley, Q. Zhang, M. Rycenga, J. Xie, C. Kim, K. H. Song, A. G. Schwartz, L. V. Wang and Y. Xia, Nature Mat. 8 935 (2009). [3.13] X. Huang and M. A. El-Sayed, J. Adv. Res. 1 13 (2010). [3.14] B. Jang, J. Y. Park, C. H. Tung, I. H. Kim and Y. Choi, ACS Nano 5 1086 (2011). [3.15] X. Huang, I. H. El-Sayed, W. Qian and M. A. El-Sayed, J. Am. Chem. Soc. 128 2115 (2006). [3.16] S. Lal, S. E. Clare and N. J. Halas, Acc. Chem. Res. 41 1842 (2008). [3.17] S. Jelveh and D. B. Chithrani, Cancers 3 1081 (2011). [3.18] M. C. Daniel and D. Astruc, Chem. Rev. 104 293 (2004). [3.19] M. Eghtedari, A. V. Liopo, J. A. Copland, A. A. Oraevsky and M. Motamedi, Nano Lett. 9 287 (2009). [3.20] W. I. Choi, J. Y. Kim, C. Kang, C. C. Byeon, Y. H. Kim and G. Tae, ACS Nano 5 1995 (2011). [3.21] G. von Maltzahn, J. H. Park, A. Agrawal, N. K. Bandaru, S. K. Das, M. J. Sailor and S. N. Bhatia, Cancer Res. 69 3892 (2009). [3.22] A. M. Gobin, J. J. Moon and J. L. West, Internal. J. Nanomed. 3 351 (2008). [3.23] A. M. Gobin, M. H. Lee, N. J. Halas, W. D. James, R. A. Drezek and J. L. West, Nano Lett. 7 1929 (2007). [3.24] L. B. Carpin, L. R. Bickford, G. Agollah, T. K. Yu, R. Schiff, Y. Li and R. A. Drezek, Breast Cancer Res. Treat. 125 27 (2011). [3.25] A. M. Schwartzberg, T. Y. Olson, C. E. Talley and J. Z. Zhang, J. Phys. Chem. B 110 19935 (2006). [3.26] J. Z. Zhang, J. Phys. Chem. Lett. 1 686 (2010). [3.27] J. Chen, D. Wang, J. Xi, L. Au, A. Siekkinen, A. Warsen, Z. Y. Li, H. Zhang, Y. Xia and X. Li, Nano Lett. 7 1318 (2007). [3.28] J. Chen, F. Saeki, B. J. Wiley, H. Cang, M. J. Cobb, Z. Y. Li, L. Au, H. Zhang, M. B. Kimmey, X. Li and Y. Xia, Nano Lett. 5 473 (2005). [3.29] J. Chen, C. Glaus, R. Laforest, Q. Zhang, M. Yang, M. Gidding, M. J. Welch and Y. Xia, Small 6 811 (2010). [3.30] M. E. Brezinski, G. J. Tearney, B. E. Bouma, J. A. Izatt, M. R. Hee, E. A. Swanson, J. F. Southern and J. G. Fujimoto, Circulation 93 1206 (1996). [3.31] E. M. Larsson, J. Alegret, M. Kall and D. S. Sutherland, Nano Lett. 7 1256 (2007). [3.32] F. Hao, E. M. Larsson, T. A. Ali, D. S. Sutherland and P. Nordlander, Chem. Phys. Lett. 458 262 (2008). [3.33] J. Aizpurua, P. Hanarp, D. S. Sutherland, M. Kall, G. W. Bryant and F. J. Garcia de Abajo, Phys. Rev. Lett. 90 057401 (2003). [3.34] T. A. Kelf, Y. Tanaka, O. Matsuda, E. M. Larsson, D. S. Sutherland and O. B. Wright, Nano Lett. 11 3893 (2011). [3.35] W. Kubo and S. Fujikawa, Nano Lett. 11 8 (2011). [3.36] C. K. Lee, H. Y. Tseng, C. Y. Lee, S. Y. Wu, T. T. Chi, K. M. Yang, H. Y. E. Chou, M. T. Tsai, J. Y. Wang, Y. W. Kiang, C. P. Chiang and C. C. Yang, Biomed. Opt. Express 1 1059 (2010). [3.37] S. Y. Wu, W. M. Chang, H. Y. Tseng, C. K. Lee, T. T. Chi, J. Y. Wang, Y. W. Kiang and C. C. Yang, Plasmonics 6 547 (2011). [3.38] K. Sokolov, M. Follen, J. Aaron, I. Pavlova, A. Malpica, R. Lotan and R. Richards-Kortum, Cancer Research 63 1999 (2003). | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/61898 | - |
dc.description.abstract | 在本論文中,我們展示高濃度金奈米環水溶液的製備方法及其應用。由於金奈米粒子具有良好的生物相容性,因此廣泛地應用於生物醫學領域,包括增強光學同調斷層掃描的影像對比、光熱治療、藥物傳遞等。常見的金奈米粒子主要經由化學合成的方式製作,這些奈米粒子的侷域表面電漿子共振波長一般位於1000奈米以內的紅外光範圍。由於波長在1300奈米的光源對生物組織擁有較大之穿透深度,因此侷域表面電漿子共振波長位於1300奈米的金奈米環較適用於較深組織的診斷與治療。在本論文中,我們首先使用奈米球微影術以及金的二次濺鍍製程,在藍寶石基板上製作金奈米環,隨後再將其轉移到水溶液內。經估計金奈米環在其共振波長的消散截面積大約為10-10-10-9 cm2。藉由控制金奈米環的幾何形狀,我們可以製作侷域表面電漿子在生物組織內共振波長為1300奈米之金奈米環。接下來,我們使金奈米環擴散入豬脂肪組織中,經由其表面電漿子共振的加強散射與吸收特性,我們可以觀察到光學同調斷層掃描影像對比明顯提升,此外,金奈米環之侷域表面電漿子共振所產生的光熱效應造成豬脂肪細胞在光學同調斷層掃描影像中因溫度上升而變為透明。
接下來,為縮短金奈米環侷域表面電漿子之共振波長,我們施展兩種製程方法使金奈米環水溶液之侷域表面電漿子共振波長可短於900奈米。我們也提出將金奈米環製作在氮化矽奈米柱結構上,以便在基板上進行金奈米環生物耦聯。 然後,我們展示使用奈米壓印技術以及金的二次濺鍍製程在高分子基板上製作生物耦聯之金奈米環,並轉移到水溶液。在基板上進行奈米環的生物耦聯具有許多優點,包括可以有效避免奈米環在離心過程中的損失,進而提升其產率。接下來,我們將生物耦聯之金奈米環施加在人類肝癌細胞中,在波長為1315奈米的雷射照射下,展示金奈米環的光熱治療效果。經由量測不同強度之雷射對細胞的殺傷範圍,我們可以推算出造成細胞損傷的臨界雷射強度。 | zh_TW |
dc.description.abstract | In this dissertation, we first demonstrate the preparation of a high-concentration Au nanoring (NRI) water solution and its applications to the enhancement of image contrast in optical coherence tomography (OCT) and the generation of photothermal effect in a bio-sample through localized surface plasmon (LSP) resonance. Au NRIs are first fabricated on a sapphire substrate with colloidal lithography and secondary sputtering of Au, and then transferred into water solution through a liftoff process. By controlling the NRI geometry, the LSP dipole resonance wavelength in tissue can cover the spectral range of 1300 nm for OCT scanning of deep tissue penetration. The extinction cross sections of the fabricated Au NRIs in water are estimated to give the levels of 10-10-10-9 cm2 near their LSP resonance wavelengths. The fabricated Au NRIs are then delivered into pig adipose samples for OCT scanning. It is observed that when resonant Au NRIs are delivered into such a sample, LSP resonance-induced Au NRI absorption results in a photothermal effect, making the opaque pig adipose cells transparent. Also, the delivered Au NRIs in the intercellular substance enhance the image contrast of OCT scanning through LSP resonance-enhanced scattering. By continuously OCT scanning a sample, both photothermal and image contrast enhancement effects are observed. However, by continually scanning a sample with a low scan frequency, only the image contrast enhancement effect is observed. We also demonstrate two fabrication methods to produce Au NRI solution with LSP resonance wavelength below 900 nm. Then, the structure of Au NRIs on SiN nanopilars are demonstrated, which can be used for on-substrate bio-conjugation of Au NRIs.
Next, The on-substrate fabrication of bio-conjugated Au NRI solution with the LSP resonance wavelength in the 1200-1300 nm range is demonstrated. Also, the effects of photothermal therapy through LSP resonance-induced absorption enhancement are illustrated by applying the bio-conjugated Au NRIs to human liver cancer cells and illuminating the cells with laser of 1315 nm in wavelength. The Au NRI fabrication is based on the techniques of nano-imprint lithography and metal secondary sputtering. The procedure for on-substrate surface modification of Au NRI leads to a high production yield of bio-conjugated NRI. The threshold levels of the local laser intensity for injuring cancer cells based on the LSP resonances of Au NRIs of two different samples are determined. | en |
dc.description.provenance | Made available in DSpace on 2021-06-16T13:17:47Z (GMT). No. of bitstreams: 1 ntu-102-D95941021-1.pdf: 4847290 bytes, checksum: 2b245c6ecf7ce63eab132599441dae5c (MD5) Previous issue date: 2013 | en |
dc.description.tableofcontents | Contents
中文摘要 i Abstract iii Contents v Chapter 1 Introduction 1.1 Localized Surface Plasmon 1 1.2 Review of Gold Nanoparticle 3 1.2.1 Gold Nanosphere 3 1.2.2 Gold Nanorod 6 1.2.3 Gold Nanoshell/Hollow Gold Nanoparticle 9 1.2.4 Gold Nanocage 11 1.3 Characteristics of Gold Nanoring 13 1.4 Optical Coherence Tomography 17 1.5 Biomedical Applications of Gold Nanoparticles 20 1.5.1 Cell Uptake of Nanoparticles 20 1.5.2 Imaging Contrast Enhancement 21 1.5.2.1 Cell Labeling 21 1.5.2.2 Using Au Nanoparticle as Contrast Agent in Optical Coherence/Doppler Tomography 23 1.5.3 Photothermal Therapy 25 1.6 Research Motivations 27 1.7 Organization of the Dissertation 29 References 30 Chapter 2 Au Nanorings for Enhancing Absorption and Backscattering Monitored with Optical Coherence Tomography 2.1 Introduction 54 2.2 Fabrication of Au Nanorings 57 2.3 Surface Plasmon Characteristics of Au Nanorings 59 2.4 Optical Coherence Tomography Images 65 2.5 Fabrication of Au nanorings with LSP resonance wavelength below 900 nm 69 2.6 Fabrication of Au nanorings on SiN nanopillars for on-substrate bio-conjugation 73 2.7 Summary 75 References 77 Chapter 3 On-substrate Fabrication of Bio-conjugated Au Nanoring Solution for Photothermal Therapy Application 3.1 Introduction 98 3.2 Surface Plasmon Resonance Characteristics of Au Nanoring 101 3.3 Fabrication of Bio-conjugated Au Nanorings 103 3.4 Photothermal Therapy Effects 109 3.5 Summary 113 References 115 Chapter 4 Conclusions 134 Publication List 136 | |
dc.language.iso | en | |
dc.title | 生物耦聯金奈米環的製作與應用 | zh_TW |
dc.title | Fabrication and Applications of Bio-conjugated Gold Nanoring | en |
dc.type | Thesis | |
dc.date.schoolyear | 101-2 | |
dc.description.degree | 博士 | |
dc.contributor.oralexamcommittee | 江衍偉(Yean-Woei Kiang),張宏鈞(Hung-Chun Chang),魏培坤(Pei-Kuen Wei),陳顯禎(Shean-Jen Chen) | |
dc.subject.keyword | 奈米環,表面電漿子,奈米粒子,生物耦聯,光熱療法,光學同調斷層掃描, | zh_TW |
dc.subject.keyword | nanoring,nanoparticle,surface,plasmon,bioconjugation,photothermal,contrast agent,optical coherence tomography, | en |
dc.relation.page | 141 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2013-07-29 | |
dc.contributor.author-college | 電機資訊學院 | zh_TW |
dc.contributor.author-dept | 光電工程學研究所 | zh_TW |
顯示於系所單位: | 光電工程學研究所 |
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