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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/54431完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 郭宗甫(Tzong-Fu Kuo) | |
| dc.contributor.author | Po-Yu Lin | en |
| dc.contributor.author | 林伯祐 | zh_TW |
| dc.date.accessioned | 2021-06-16T02:56:31Z | - |
| dc.date.available | 2020-07-20 | |
| dc.date.copyright | 2015-07-20 | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2015-07-08 | |
| dc.identifier.citation | 陳柏文。(2011) 檸檬之產銷調節。農政與農情
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/54431 | - |
| dc.description.abstract | IV
中文摘要 骨質疏鬆症是普遍存在且好發於骨骼上的疾病，其特徵為造成骨量減少和骨礦物質密度降低，進而容易導致骨骼受損影響的強度和提高機率產生骨折。 本研究建立了動物的卵巢切除術（OVX），利用小鼠模擬人類女性絕經後骨質疏鬆模式，並利用洋蔥，檸檬和骨碎補單方和複方進行飲食的影響治療。 手術後2週等其傷口復原進行8週的治療餵食(a)洋蔥0.7g(b)檸檬0.7g(c)骨碎補(d) 洋蔥0.25g/檸檬0.25g/骨碎補0.25g等呈顯著影響骨質量與所有其他組的OVX小鼠比較。最後使用微電腦斷層掃描造 影檢視相關骨質指標，發現經由治療後小鼠具有提高BV/TV(Bone volume/total tissue volume)、骨小樑數量(Trabecular Number)、骨小樑厚度(Trabecular Thickness)、BMD(Bone Mineral Density) 並能降低骨小樑分離度(Trabecular Separation)與OVX組小鼠相比。然而對於血清中的游離鈣及無機磷，數值顯示實驗中各組間無差異顯著。這些結果表示了利用單方或複方的洋蔥、檸檬、骨碎補能夠延緩因為雌激素缺乏造成的骨質疏鬆症及降低引發的骨缺損風險。 | zh_TW |
| dc.description.abstract | Osteoporosis (OP) is the most prevalent skeletal disorder characterized by decreased bone mass and bone mineral density, which leads to impaired skeletal strength and increased susceptibility to fractures. This experiment established the ovariectomized (OVX) mouse model of postmenopausal osteoporosis, and examined the effect of supplementation with drinks and foods containing single and combination formulas comprising onion, lemon and Drynaria fortunei J. Sm. on ad libitum food intake and on bone mineral density (BMD). Two weeks after osteoporosis had been induced and 8 weeks after feeding had begun the tibia BMD of OVX mice administered (a) onion 0.7g, (b) lemon 0.7g, (c) Drynaria fortune 0.7g, and (d) onion 0.25g/lemon 0.25g/Drynaria fortune 0.25g showed significant increases compared with that of all other groups of OVX mice. Closer examination using microcomputed tomography (micro-CT) also revealed that the (a)(b)(c)(d)-administered mice had denser trabecular bone volume/tissue volume (BV/TV) and a higher trabecular number (Tb.N)、Trabecular thickness(Tb.Th)、BMD values compared to all other mouse groups, whereas trabecular separation (Tb.Sp) was significantly lower in the OVX group. As for the serum calcium and phosphorus, the values showed no significant differences among all groups in our experiment. These findings indicate that administration of single and combination formulas comprising onion, lemon and Drynaria fortunei could retard bone loss induced by estrogen deficiency and reduce the risk of osteoporosis. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-16T02:56:31Z (GMT). No. of bitstreams: 1 ntu-104-R02629011-1.pdf: 3304867 bytes, checksum: dad15f3b93f457c244f84d2f5473a203 (MD5) Previous issue date: 2015 | en |
| dc.description.tableofcontents | 口試委員會審定書 I
致謝 II 縮寫表 III 中文摘要 IV 目錄 VI 表目錄 VIII 圖目錄 IX 第壹章 文獻回顧 1 一、 洋蔥的簡介 1 (一) 洋蔥的種類 1 (二) 降血脂的能力 1 (三) 抗氧化的能力 2 (四) 抗骨質疏鬆的能力 2 二、 檸檬的簡介 5 (一) 抗氧化功效 5 (二) 降血壓功能 6 (三) 抗骨質疏鬆功效 6 三、 骨碎補的簡介 7 (一) 骨碎補的種類 7 (二) 抗骨質疏鬆功效 9 四、 食品中類相關黃酮介紹 11 五、 骨質疏鬆介紹 12 (一) 骨骼簡介 12 (二) 骨質疏鬆誘發成因 13 (三) 常見之治療方法 13 六、 骨質疏鬆動物模式介紹 16 第貳章 研究動機與目的 17 第参章 材料與方法 18 一、 材料選擇 18 二、 儀器 18 三、 實驗動物之飼養 18 四、 實驗動物之分組 19 五、 骨質疏鬆模式小鼠之誘導 19 六、 試驗物質與餵食劑量訂定 20 七、 微電腦斷層掃描之測量 20 八、 微電腦斷層掃描骨質之參數 21 九、 動物犧牲、採血及脛骨切片鏡檢 21 十、 血液骨質生化指標之測定 22 十一、 資料分析 22 第肆章 實驗結果 23 一、 動物體重紀錄 23 二、 電腦斷層掃描造影系統分析 23 三、 骨組織切片 25 四、 血液之鈣磷生化分析 26 第伍章 實驗討論 27 一、 動物模式及體重 27 二、 微電腦斷層掃描分析骨質參數 28 三、 骨組織切片分析 29 四、 血液之生化分析 30 第陸章 結論 31 第柒章 參考文獻 33 論文作者簡介 68 | |
| dc.language.iso | zh-TW | |
| dc.subject | 骨碎補 | zh_TW |
| dc.subject | 檸檬 | zh_TW |
| dc.subject | 洋蔥 | zh_TW |
| dc.subject | 骨質疏鬆症 | zh_TW |
| dc.subject | 微電腦斷層掃描 | zh_TW |
| dc.subject | 檸檬 | zh_TW |
| dc.subject | 骨碎補 | zh_TW |
| dc.subject | 洋蔥 | zh_TW |
| dc.subject | 骨質疏鬆症 | zh_TW |
| dc.subject | 微電腦斷層掃描 | zh_TW |
| dc.subject | Onion | en |
| dc.subject | Microcomputed tomography | en |
| dc.subject | Drynaria fortunei J. Sm. | en |
| dc.subject | Lemon | en |
| dc.subject | Onion | en |
| dc.subject | Osteoporosis | en |
| dc.subject | Microcomputed tomography | en |
| dc.subject | Drynaria fortunei J. Sm. | en |
| dc.subject | Lemon | en |
| dc.subject | Osteoporosis | en |
| dc.title | 洋蔥、檸檬及骨碎補單方或複方對骨質疏鬆症之影響:以卵巢截除小鼠為模式 | zh_TW |
| dc.title | The Effect of Single or Combination Formulas Comprising of Onion, Lemon and Drynaria fortunei J. Sm on Osteoporosis. A Menopausal Ovariectomized Mice Model. | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 103-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 徐鳳麟(Shao-Chien Hsu),劉朝鑫(Chaw-King Liu),許世源(Shi-Yuan Sheu) | |
| dc.subject.keyword | 骨質疏鬆症,洋蔥,檸檬,骨碎補,微電腦斷層掃描, | zh_TW |
| dc.subject.keyword | Osteoporosis,Onion,Lemon,Drynaria fortunei J. Sm.,Microcomputed tomography, | en |
| dc.relation.page | 72 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2015-07-08 | |
| dc.contributor.author-college | 獸醫專業學院 | zh_TW |
| dc.contributor.author-dept | 獸醫學研究所 | zh_TW |
| 顯示於系所單位： | 獸醫學系 | |
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