請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51985完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 徐瑋勵(Wei-Li Hsu) | |
| dc.contributor.author | Wen-Chieh Yang | en |
| dc.contributor.author | 楊文傑 | zh_TW |
| dc.date.accessioned | 2021-06-15T14:01:19Z | - |
| dc.date.available | 2016-09-24 | |
| dc.date.copyright | 2015-09-24 | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2015-08-20 | |
| dc.identifier.citation | 1. Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008;79:368-379
2. Davie CA. A review of Parkinson's disease. Br Med Bull. 2008;86:109-127 3. Obeso JA, Rodríguez-Oroz MC, Benitez-Temino B, Blesa FJ, Guridi J, Marin C, et al. Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease. Mov Disord. 2008;23:S548-559 4. Takakusaki K, Saitoh K, Harada H, Kashiwayanagi M. Role of basal ganglia-brainstem pathways in the control of motor behaviors. Neurosci Res. 2004;50:137-151 5. Boonstra TA, van der Kooij H, Munneke M, Bloem BR. Gait disorders and balance disturbances in Parkinson's disease: clinical update and pathophysiology. Curr Opin Neurol. 2008;21:461-471 6. Stack E, Ashburn A. Dysfunctional turning in Parkinson's disease. Disabil Rehabil. 2008;30:1222-1229 7. Carpinella I, Crenna P, Calabrese E, Rabuffetti M, Mazzoleni P, Nemni R, et al. Locomotor function in the early stage of Parkinson's disease. Neural Systems and Rehabilitation Engineering, IEEE Transactions on. 2007;15:543-551 8. Crenna P, Carpinella I, Rabuffetti M, Calabrese E, Mazzoleni P, Nemni R, et al. The association between impaired turning and normal straight walking in Parkinson's disease. Gait Posture. 2007;26:172-178 9. Shine J, Moore S, Bolitho S, Morris T, Dilda V, Naismith S, et al. Assessing the utility of Freezing of Gait questionnaires in Parkinson’s Disease. Parkinsonism Relat Disord. 2012;18:25-29 10. Grasso R, Prévost P, Ivanenko YP, Berthoz A. Eye-head coordination for the steering of locomotion in humans: an anticipatory synergy. Neurosci Lett. 1998;253:115-118 11. Patla AE, Adkin A, Ballard T. Online steering: coordination and control of body center of mass, head and body reorientation. Exp Brain Res. 1999;129:629-634 12. Imai T, Moore ST, Raphan T, Cohen B. Interaction of the body, head, and eyes during walking and turning. Exp Brain Res. 2001;136:1-18 13. Vaugoyeau M, Viallet F, Aurenty R, Assaiante C, Mesure S, Massion J. Axial rotation in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2006;77:815-821 14. Akram S, Frank JS, Jog M. Parkinson's disease and segmental coordination during turning: I. Standing turns. Can J Neurol Sci. 2013;40:512-519 15. Hong M, Earhart GM. Effects of medication on turning deficits in individuals with Parkinson's disease. J Neurol Phys Ther. 2010;34:11-16 16. Plotnik M, Giladi N, Hausdorff JM. A new measure for quantifying the bilateral coordination of human gait: effects of aging and Parkinson's disease. Exp Brain Res. 2007;181:561-570 17. Hausdorff JM, Schaafsma JD, Balash Y, Bartels AL, Gurevich T, Giladi N. Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait. Exp Brain Res. 2003;49:187-194 18. Baltadjieva R, Giladi N, Gruendlinger L, Peretz C, Hausdorff JM. Marked alterations in the gait timing and rhythmicity of patients with de novo Parkinson's disease. Eur J Neurosci. 2006;24:1815-1820 19. Hollands MA, Sorensen KL, Patla AE. Effects of head immobilization on the coordination and control of head and body reorientation and translation during steering. Exp Brain Res. 2001;140:223-233 20. Mak MKY, Patla A, Hui-Chan C. Sudden turn during walking is impaired in people with Parkinson’s disease. Exp Brain Res. 2008;190:43-51 21. Morris ME. Movement disorders in people with Parkinson disease: a model for physical therapy. Phys Ther. 2000;80:578-597 22. KNGF Guidelines for physical therapy in patients with Parkinson's disease. Dutch Journal of Physiotherapy. 2004;114 23. Rubinstein TC, Giladi N, Hausdorff JM. The power of cueing to circumvent dopamine deficits: a review of physical therapy treatment of gait disturbances in Parkinson's disease. Mov Disord. 2002;17:1148-1160 24. Lim I, van Wegen E, de Goede C, Deutekom M, Nieuwboer A, Willems A, et al. Effects of external rhythmical cueing on gait in patients with Parkinson's disease: a systematic review. Clin Rehabil. 2005;19:695-713 25. Müller V, Mohr B, Rosin R, Pulvermüller F, Müller F, Birbaumer N. Short-term effects of behavioral treatment on movement initiation and postural control in Parkinson's disease: a controlled clinical study. Mov Disord. 1997;12:306-314 26. Nieuwboer A, De Weerdt W, Dom R, Truyen M, Janssens L, Kamsma Y. The effect of a home physiotherapy program for persons with Parkinson's disease. J Rehabil Med. 2001;33:266-272 27. Morris ME, Iansek R, Kirkwood B. A randomized controlled trial of movement strategies compared with exercise for people with Parkinson's disease. Mov Disord. 2009;24:64-71 28. Nieuwboer A. Cueing for freezing of gait in patients with Parkinson's disease: A rehabilitation perspective. Mov Disord. 2008;23:S475-481 29. Keus SH, Bloem BR, Hendriks EJ, Bredero-Cohen AB, Munneke M. Evidence-based analysis of physical therapy in Parkinson's disease with recommendations for practice and research. Mov Disord. 2007;22:451-460 30. McIntosh GC, Brown SH, Rice RR, Thaut MH. Rhythmic auditory-motor facilitation of gait patterns in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1997;62:22-26 31. Lohnes CA, Earhart GM. The impact of attentional, auditory, and combined cues on walking during single and cognitive dual tasks in Parkinson disease. Gait Posture. 2011;33:478-483 32. Morris M, McGinley J, Huxham F, Collier J, Iansek R. Constraints on the kinetic, kinematic and spatiotemporal parameters of gait in Parkinson's disease. Hum Mov Sci. 1999;18:461-483 33. Morris ME, Iansek R, Matyas TA, Summers JJ. The pathogenesis of gait hypokinesia in Parkinson's disease. Brain. 1994;117:1169-1181 34. Burleigh-Jacobs A, Horak FB, Nutt JG, Obeso JA. Step initiation in Parkinson's disease: influence of levodopa and external sensory triggers. Mov Disord. 1997;12:206-215 35. Martin M, Shinberg M, Kuchibhatla M, Ray L, Carollo JJ, Schenkman ML. Gait initiation in community-dwelling adults with Parkinson disease: Comparison with older and younger adults without the disease. Phys Ther. 2002;82:566-577 36. Hass CJ, Waddell DE, Fleming RP, Juncos JL, Gregor RJ. Gait initiation and dynamic balance control in Parkinson's disease. Arch Phys Med Rehabil. 2005;86:2172-2176 37. Rocchi L, Chiari L, Mancini M, Carlson-Kuhta P, Gross A, Horak FB. Step initiation in Parkinson's disease: influence of initial stance conditions. Neurosci Lett. 2006;206:128-132 38. Rochester L, Nieuwboer A, Baker K, Hetherington V, Willems AM, Chavret F, et al. The attentional cost of external rhythmical cues and their impact on gait in Parkinson's disease: effect of cue modality and task complexity. J Neural Transm. 2007;114:1243-1248 39. Spildooren J, Vercruysse S, Meyns P, Vandenbossche J, Heremans E, Desloovere K, et al. Turning and unilateral cueing in Parkinson's disease patients with and without freezing of gait. Neuroscience. 2012;207:298-306 40. Keus SH, Munneke M, Nijkrake MJ, Kwakkel G, Bloem BR. Physical therapy in Parkinson's disease: Evolution and future challenges. Mov Disord. 2009;24:1-14 41. Dorociak RD. A comparison of normal kinematics for Vicon clinical manager and plug in gait. Gait Posture. 2002;16:S102-103 42. Shumway-Cook A, Woollacott M. Motor Control Theory and Applications. Baltimore: Williams & Wilkins; 1995. 43. Lee HJ, Chou LS. Detection of gait instability using the center of mass and center of pressure inclination angles. Arch Phys Med Rehabil. 2006;87:569-575 44. Woollacott M, Shumway-Cook A. Attention and the control of posture and gait: a review of an emerging area of research. Gait Posture. 2002;16:1-14 45. Bloem BR, Grimbergen YA, van Dijk JG, Munneke M. The 'posture second' strategy: a review of wrong priorities in Parkinson's disease. J Neurol Sci. 2006;248:196-204 46. Lacour M, Bernard-Demanze L, Dumitrescu M. Posture control, aging, and attention resources: models and posture-analysis methods. Neurophysiol Clin. 2008;38:411-421 47. Bloem BR, Valkenburg VV, Slabbekoorn M, Willemsen MD. The Multiple Tasks Test: development and normal strategies. Gait Posture. 2001;14:191-202 48. Bloem BR, Hausdorff JM, Visser JE, Giladi N. Falls and freezing of gait in Parkinson's disease: a review of two interconnected, episodic phenomena. Mov Disord. 2004;19:871-884 49. Giladi N, Nieuwboer A. Understanding and treating freezing of gait in parkinsonism, proposed working definition, and setting the stage. Mov Disord. 2008;23:S423-425 50. Vedel JP, Roll JP. Response to pressure and vibration of slowly adapting cutaneous mechanoreceptors in the human foot. Neurosci Lett. 1982;34:289-294 51. Ribot-Ciscar E, Vedel JP, Roll JP. Vibration sensitivity of slowly and rapidly adapting cutaneous mechanoreceptors in the human foot and leg. Neurosci Lett. 1989;104:130-135 52. Hase K, Stein RB. Turning strategies during human walking. J Neurophysiol. 1999;81:2914-2922 53. Courtine G, Schieppati M. Human walking along a curved path. I. Body trajectory, segment orientation and the effect of vision. Eur J Neurosci. 2003;18:177-190 54. Visser JE, Voermans NC, Oude Nijhuis LB, van der Eijk M, Nijk R, Munneke M, et al. Quantification of trunk rotations during turning and walking in Parkinson's disease. Clin Neurophysiol. 2007;118:1602-1606 55. Yardley L, Gardner M, Bronstein A, Davies R, Buckwell D, Luxon L. Interference between postural control and mental task performance in patients with vestibular disorder and healthy controls. J Neurol Neurosurg Psychiatry. 2001;71:48-52 56. Pocock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics. 1975;31:103-115 57. Grimbergen YA, Munneke M, Bloem BR. Falls in Parkinson's disease. Curr Opin Neurol. 2004;17:405-415 58. Hollands MA, Patla AE, Vickers JN. 'Look where you're going!': gaze behaviour associated with maintaining and changing the direction of locomotion. Exp Brain Res. 2002;143:221-230 59. Van Emmerik REA, Wagenaar RC, Winogrodzka A, Wolters EC. Identification of axial rigidity during locomotion in Parkinson disease. Arch Phys Med Rehabil. 1999;80:186-191 60. Huxham F, Baker R, Morris ME, Iansek R. Head and trunk rotation during walking turns in Parkinson's disease. Mov Disord. 2008;23:1391-1397 61. Hong M, Perlmutter JS, Earhart GM. A kinematic and electromyographic analysis of turning in people with Parkinson disease. Neurorehabil Neural Repair. 2009;23:166-176 62. Lamontagne A, Paquette C, Fung J. Stroke affects the coordination of gaze and posture during preplanned turns while walking. Neurorehabil Neural Repair. 2007;21:62-67 63. Lamontagne A, Fung J. Gaze and postural reorientation in the control of locomotor steering after stroke. Neurorehabil Neural Repair. 2009;23:256-266 64. Vallis LA, Patla AE, Adkin AL. Control of steering in the presence of unexpected head yaw movements. Influence on sequencing of subtasks. Exp Brain Res. 2001;138:128-134 65. Huxham F, Baker R, Morris ME, Iansek R. Footstep adjustments used to turn during walking in Parkinson's disease. Mov Disord. 2008;23:817-823 66. Mandeville D, Osternig LR, Chou LS. The effect of total knee replacement surgery on gait stability. Gait Posture. 2008;27:103-109 67. Lee HJ, Chou LS. Balance control during stair negotiation in older adults. J Biomech. 2007;40:2530-2536 68. Giladi N, Tal J, Azulay T, Rascol O, Brooks DJ, Melamed E, et al. Validation of the freezing of gait questionnaire in patients with Parkinson's disease. Mov Disord. 2009;24:655-661 69. Podsiadlo D, Richardson S. The timed 'Up & Go': a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39:142-148 70. Solomon D, Vijay K, Jenkins RA, Jewell J. Head control strategies during whole-body turns. Exp Brain Res. 2006;173:475-486 71. Franzén E, Paquette C, Gurfinkel VS, Cordo PJ, Nutt JG, Horak FB. Reduced performance in balance, walking and turning tasks is associated with increased neck tone in Parkinson's disease. Exp Neurol. 2009;219:430-438 72. Winter DA. Human balance and posture control during standing and walking. Gait Posture. 1995;3:193-214 73. Huang SC, Lu TW, Chen HL, Wang TM, Chou LS. Age and height effects on the center of mass and center of pressure inclination angles during obstacle-crossing. Med Eng Phys. 2008;30:968-975 74. Chee R, Murphy A, Danoudis M, Georgiou-Karistianis N, Iansek R. Gait freezing in Parkinson's disease and the stride length sequence effect interaction. Brain. 2009;132:2151-2160 75. Iansek R, Huxham F, McGinley J. The sequence effect and gait festination in Parkinson disease: contributors to freezing of gait? Mov Disord. 2006;21:1419-1424 76. King LA, Mancini M, Priest K, Salarian A, Rodrigues-de-Paula F, Horak F. Do clinical scales of balance reflect turning abnormalities in people with Parkinson's disease? J Neurol Phys Ther. 2012;36:25-31 77. Gurfinkel V, Cacciatore TW, Cordo P, Horak F, Nutt J, Skoss R. Postural muscle tone in the body axis of healthy humans. J Neurophysiol. 2006;96:2678-2687 78. Yogev G, Giladi N, Peretz C, Springer S, Simon ES, Hausdorff JM. Dual tasking, gait rhythmicity, and Parkinson's disease: which aspects of gait are attention demanding? Eur J Neurosci. 2005;22:1248-1256 79. Yogev G, Plotnik M, Peretz C, Giladi N, Hausdorff J. Gait asymmetry in patients with Parkinson’s disease and elderly fallers: when does the bilateral coordination of gait require attention? Exp Brain Res. 2007;177:336-346 80. Plotnik M, Hausdorff JM. The role of gait rhythmicity and bilateral coordination of stepping in the pathophysiology of freezing of gait in Parkinson's disease. Mov Disord. 2008;23:S44-50 81. Tariq SH, Tumosa N, Chibnall JT, Perry MH, Morley JE. Comparison of the Saint Louis University mental status examination and the mini-mental state examination for detecting dementia and mild neurocognitive disorder--a pilot study. Am J Geriatr Psychiatry. 2006;14:900-910 82. Han B, Enas NH, McEntegart D. Randomization by minimization for unbalanced treatment allocation. Stat Med. 2009;28:3329-3346 83. Hausdorff JM, Cudkowicz ME, Firtion R, Wei JY, Goldberger AL. Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson's disease and Huntington's disease. Mov Disord. 1998;13:428-437 84. Conover WJ, Iman RL. Rank transformations as a bridge between parametric and nonparametric statistics. Am Stat. 1981;35:124-129 85. Nieuwboer A, Rochester L, Müncks L, Swinnen SP. Motor learning in Parkinson's disease: limitations and potential for rehabilitation. Parkinsonism Relat Disord. 2009;15:S53-58 86. Abbruzzese G, Trompetto C, Marinelli L. The rationale for motor learning in Parkinson's disease. Eur J Phys Rehabil Med. 2009;45:209-214 87. Canning CG. The effect of directing attention during walking under dual-task conditions in Parkinson's disease. Parkinsonism Relat Disord. 2005;11:95-99 88. Baker K, Rochester L, Nieuwboer A. The immediate effect of attentional, auditory, and a combined cue strategy on gait during single and dual tasks in Parkinson's disease. Arch Phys Med Rehabil. 2007;88:1593-1600 89. Nutt JG, Bloem BR, Giladi N, Hallett M, Horak FB, Nieuwboer A. Freezing of gait: moving forward on a mysterious clinical phenomenon. Lancet Neurol. 2011;10:734-744 90. Nieuwboer A, Dom R, De Weerdt W, Desloovere K, Fieuws S, Broens-Kaucsik E. Abnormalities of the spatiotemporal characteristics of gait at the onset of freezing in Parkinson's disease. Mov Disord. 2001;16:1066-1075 91. Lewek MD, Poole R, Johnson J, Halawa O, Huang X. Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's disease. Gait Posture. 2010;31:256-260 92. Spildooren J, Vercruysse S, Desloovere K, Vandenberghe W, Kerckhofs E, Nieuwboer A. Freezing of gait in Parkinson's disease: the impact of dual-tasking and turning. Mov Disord. 2010;25:2563-2570 93. Okuma Y. Freezing of gait in Parkinson's disease. J Neurol. 2006;253:VII27-32 94. Moore O, Peretz C, Giladi N. Freezing of gait affects quality of life of peoples with Parkinson's disease beyond its relationships with mobility and gait. Mov Disord. 2007;22:2192-2195 95. Breniere Y, Do MC, Bouisset S. Are dynamic phenomena prior to stepping essential to walking? J Mot Behav. 1987;19:62-76 96. Brenière Y, Do MC. Control of gait initiation. J Mot Behav. 1991;23:235-240 97. Lepers R, Brenière Y. The role of anticipatory postural adjustments and gravity in gait initiation. Exp Brain Res. 1995;107:118-124 98. Jacobs JV, Nutt JG, Carlson-Kuhta P, Stephens M, Horak FB. Knee trembling during freezing of gait represents multiple anticipatory postural adjustments. Exp Neurol. 2009;215:334-341 99. Kavounoudias A, Roll R, Roll JP. The plantar sole is a 'dynamometric map' for human balance control. Neuroreport. 1998;9:3247-3252 100. Kavounoudias A, Roll R, Roll JP. Specific whole-body shifts induced by frequency-modulated vibrations of human plantar soles. Neurosci Lett. 1999;266:181-184 101. Roll R, Kavounoudias A, Roll JP. Cutaneous afferents from human plantar sole contribute to body posture awareness. Neuroreport. 2002;13:1957-1961 102. Kavounoudias A, Roll R, Roll JP. Foot sole and ankle muscle inputs contribute jointly to human erect posture regulation. J Physiol. 2001;532:869-878 103. Moore ST, MacDougall HG, Ondo WG. Ambulatory monitoring of freezing of gait in Parkinson's disease. J Neurosci Methods. 2008;167:340-348 104. Bächlin M, Hausdorff JM, Roggen D, Giladi N, Plotnik M, Tröster G. Online detection of freezing of gait in Parkinson's disease patients: a performance characterization. Proceeding BodyNets. 2009 105. Giladi N, Shabtai H, Simon ES, Biran S, Tal J, Korczyn AD. Construction of freezing of gait questionnaire for patients with Parkinsonism. Parkinsonism Relat Disord. 2000;6:165-170 106. Hausdorff JM, Balash Y, Giladi N. Time series analysis of leg movements during freezing of gait in Parkinson's disease: akinesia, rhyme or reason? Physica A. 2003;321:565-570 107. Huxham F, Gong J, Baker R, Morris M, Iansek R. Defining spatial parameters for non-linear walking. Gait Posture. 2006;23:159-163 108. Schaafsma JD, Balash Y, Gurevich T, Bartels AL, Hausdorff JM, Giladi N. Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease. Eur J Neurol. 2003;10:391-398 109. Velik R, Hoffmann U, Zabaleta H, Marti Masso JF, Keller T. The effect of visual cues on the number and duration of freezing episodes in Parkinson's patients. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE. 2012:4656-4659 110. Nieuwboer A, Baker K, Willems AM, Jones D, Spildooren J, Lim I, et al. The short-term effects of different cueing modalities on turn speed in people with Parkinson's disease. Neurorehabil Neural Repair. 2009;23:831-836 111. Hausdorff JM, Lowenthal J, Herman T, Gruendlinger L, Peretz C, Giladi N. Rhythmic auditory stimulation modulates gait variability in Parkinson's disease. Eur J Neurosci. 2007;26:2369-2375 112. Lewis GN, Byblow WD, Walt SE. Stride length regulation in Parkinson's disease: the use of extrinsic, visual cues. Brain. 2000;123:2077-2090 113. Alice N, Fabienne C, Anne-Marie W, Kaat D. Does freezing in Parkinson's disease change limb coordination? A kinematic analysis. J Neurol. 2007;254:1268-1277 114. Petzinger GM, Fisher BE, McEwen S, Beeler JA, Walsh JP, Jakowec MW. Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. Lancet Neurol. 2013;12:716-726 115. Baker K, Rochester L, Nieuwboer A. The effect of cues on gait variability--reducing the attentional cost of walking in people with Parkinson's disease. Parkinsonism Relat Disord. 2008;14:314-320 116. Yin HH, Knowlton BJ. The role of the basal ganglia in habit formation. Nat Rev Neurosci. 2006;7:464-476 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51985 | - |
| dc.description.abstract | 目的：本論文使用動作分析，以三個研究探討巴金森患者的轉身困難。研究一比較巴金森患者與同齡健康成人在轉身時軀幹肢段間協調與姿勢穩定上的差異。研究二探討一種認知動作策略，即「時鐘轉」技巧，對巴金森患者轉身過程步態穩定度、凝凍步態與轉身表現的影響；研究三探討即時體感覺提示對轉身過程的體重轉移與凝凍步態的影響。方法：三個研究皆採橫斷式設計，並以三維動作捕捉系統紀錄受試者行走與轉身中的肢段動作。研究招募原發性巴金森且有凝凍步態的患者，並於藥物停電期執行試驗。結果：研究ㄧ，巴金森患者的軀幹肢段在轉身時呈同時轉動，而同齡健康成人則呈由頭至尾依序轉動。同時巴金森患者較同齡健康成人具有較大的側向不穩與較小的前向推進。研究二，使用時鐘轉策略的巴金森患者較不使用策略的患者在轉身時有較低的跨步時間變異度與不對稱度。同時使用時鐘轉策略的患者較不使用策略的患者以較短的時間完成轉身，並在轉身中發生較少的凝凍步態。研究三，巴金森患者在給予即時體感覺提示下，於重啟跨步時有較大的體重轉移與跨步長。同時，巴金森患者在給予即時體感覺提示下，以較少的跨步完成轉身，且轉身過程凝凍步態的持續時間較短。結論：本論文驗證不同介入方式對改善巴金森患者轉身困難的效益，建議未來研究可從中樞控制的面向進一步探究這些效益的原理。 | zh_TW |
| dc.description.abstract | Purpose: This dissertation included three studies using motion analysis to address turning difficulty in people with Parkinson’s disease (PD). Study 1 compared the truncal coordination and postural stability during turning between PD and healthy adults. Study 2 investigated the effect of a cognitive movement strategy, the clock-turn strategy, on gait stability, freezing of gait and turning performance. Study 3 investigated the effect of a real-time somatosensory cue on weight shift and freezing of gait during turning.
Methods: All three studies were cross-sectional, and employed a 3D motion capture system to record participants’ movements. Idiopathic PD with freezing of gait were enrolled and took the studies during medication OFF period. Results: In study 1, PD showed a simultaneous rotation of truncal segments during turning rather than a craniocaudal sequence seen in healthy adults. Moreover, PD had greater frontal instability and less sagittal progression than healthy adults. In study 2, PD using the clock-turn strategy had lower gait variability and asymmetry than PD not using the strategy. Moreover, PD with the strategy had fewer freezing episodes and turned faster than PD without the strategy. In study 3, PD showed greater weight shift and step length at the reinitiation step in trials with the real-time somatosensory cue than trials without cue. Moreover, PD had fewer turning steps and shorter freezing duration in trials with cue than trials without cue. Conclusion: This dissertation verified the effects of different intervention approaches for resolving turning difficulty in people with PD. Future studies are suggested to investigate the mechanisms contributing to these effects from the central control perspective. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T14:01:19Z (GMT). No. of bitstreams: 1 ntu-104-D98428003-1.pdf: 14913951 bytes, checksum: 4098059a3c189f3e99674ad61e4d9858 (MD5) Previous issue date: 2015 | en |
| dc.description.tableofcontents | 論文口試委員審定書 1
致謝 2 Abstract 3 摘要 4 Table of contents 5 List of tables 7 List of figures 8 1. Introduction 9 1.1. Overview of Parkinson’s disease 9 1.2. Turning difficulty in people with Parkinson's disease 12 1.3. Physical therapy for turning difficulty 13 2. Purposes 19 2.1. Knowledge gap 19 2.2. Research hypotheses 20 3. Methods of study 22 3.1. Equipment 22 3.2. Operational definition 24 4. STUDY 1: Axial coordination during turning 27 4.1. Abstract 27 4.2. Introduction 28 4.3. Methods 29 4.4. Results 36 4.5. Discussion 42 4.6. Conclusion 45 5. STUDY 2: Effect of the clock-turn strategy on turning 46 5.1. Abstract 46 5.2. Introduction 47 5.3. Methods 48 5.4. Results 53 5.5. Discussion 57 5.6. Conclusion 61 6. STUDY 3: Effect of the real-time somatosensory cue on turning 62 6.1. Abstract 62 6.2. Introduction 63 6.3. Methods 64 6.4. Results 73 6.5. Discussion 76 6.6. Conclusion 80 7. Summary and conclusion 81 8. References 87 9. Appendix 97 9.1. Inform consents 97 9.2. Conference publications 107 9.3. Journal publications 114 | |
| dc.language.iso | en | |
| dc.subject | 動作分析 | zh_TW |
| dc.subject | 巴金森 | zh_TW |
| dc.subject | 轉身 | zh_TW |
| dc.subject | 凝凍步態 | zh_TW |
| dc.subject | Turning | en |
| dc.subject | Motion analysis | en |
| dc.subject | Freezing of gait | en |
| dc.subject | Parkinson’s disease | en |
| dc.title | 認知動作策略與即時體感覺提示對巴金森患者轉身動作的立即效應 | zh_TW |
| dc.title | Immediate effect of cognitive movement strategy and real-time somatosensory cue on turning in people with Parkinson's disease | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 103-2 | |
| dc.description.degree | 博士 | |
| dc.contributor.coadvisor | 林光華(Kwan-Hwa Lin) | |
| dc.contributor.oralexamcommittee | 吳瑞美(Ruey-Meei Wu),呂東武(Tung-Wu Lu),丁建均(Jian-Jiun Ding) | |
| dc.subject.keyword | 巴金森,轉身,凝凍步態,動作分析, | zh_TW |
| dc.subject.keyword | Parkinson’s disease,Turning,Freezing of gait,Motion analysis, | en |
| dc.relation.page | 118 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2015-08-20 | |
| dc.contributor.author-college | 醫學院 | zh_TW |
| dc.contributor.author-dept | 物理治療學研究所 | zh_TW |
| 顯示於系所單位： | 物理治療學系所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-104-1.pdf 未授權公開取用 | 14.56 MB | Adobe PDF |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。