請用此 Handle URI 來引用此文件:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51371
完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 葉俊毅(Chun-I Yeh) | |
dc.contributor.author | Sheng-Hui Wu | en |
dc.contributor.author | 吳聲暉 | zh_TW |
dc.date.accessioned | 2021-06-15T13:32:00Z | - |
dc.date.available | 2018-02-26 | |
dc.date.copyright | 2016-02-26 | |
dc.date.issued | 2016 | |
dc.date.submitted | 2016-02-02 | |
dc.identifier.citation | Ahmad, K. M., Klug, K., Herr, S., Sterling, P., & Schein, S. (2003). Cell density ratios in a foveal patch in macaque retina. Vis Neurosci, 20(2), 189-209.
Alexander, K. R., Xie, W., & Derlacki, D. J. (1993). The effect of contrast polarity on letter identification. Vision Research, 33(17), 2491-2497. Brainard, D. H. (1997). The Psychophysics Toolbox. Spat Vis, 10(4), 433-436. Busse, L., Ayaz, A., Dhruv, N. T., Katzner, S., Saleem, A. B., Scholvinck, M. L., . . . Carandini, M. (2011). The detection of visual contrast in the behaving mouse. J Neurosci, 31(31), 11351-11361. doi:10.1523/JNEUROSCI.6689-10.2011 Campi, K. L., & Krubitzer, L. (2010). Comparative studies of diurnal and nocturnal rodents: differences in lifestyle result in alterations in cortical field size and number. J Comp Neurol, 518(22), 4491-4512. doi:10.1002/cne.22466 Dannemiller, J. L., & Stephens, B. R. (2001). Asymmetries in contrast polarity processing in young human infants. J Vis, 1(2), 112-125. doi:10:1167/1.2.5 Gianfranceschi, L., Fiorentini, A., & Maffei, L. (1999). Behavioural visual acuity of wild type and bcl2 transgenic mouse. Vision Res, 39(3), 569-574. Girman, S. V., Sauve, Y., & Lund, R. D. (1999). Receptive field properties of single neurons in rat primary visual cortex. J Neurophysiol, 82(1), 301-311. Glickfeld, L. L., Histed, M. H., & Maunsell, J. H. R. (2013). Mouse Primary Visual Cortex Is Used to Detect Both Orientation and Contrast Changes. The Journal of Neuroscience, 33(50), 19416-19422. doi:10.1523/jneurosci.3560-13.2013 Grubb, M. S., & Thompson, I. D. (2003). Quantitative Characterization of Visual Response Properties in the Mouse Dorsal Lateral Geniculate Nucleus. Journal of Neurophysiology, 90(6), 3594-3607. doi:10.1152/jn.00699.2003 Hensch, T. K. (2005). Critical period mechanisms in developing visual cortex. Curr Top Dev Biol, 69, 215-237. doi:10.1016/S0070-2153(05)69008-4 Huberman, A. D., & Niell, C. M. (2011). What can mice tell us about how vision works? Trends in Neurosciences, 34(9), 464-473. doi:10.1016/j.tins.2011.07.002 Jiang, Y., Purushothaman, G., & Casagrande, V. A. (2015). The functional asymmetry of ON and OFF channels in the perception of contrast. J Neurophysiol, 114(5), 2816-2829. doi:10.1152/jn.00560.2015 Jin, J. Z., Weng, C., Yeh, C.-I., Gordon, J. A., Ruthazer, E. S., Stryker, M. P., . . . Alonso, J.-M. (2008). On and off domains of geniculate afferents in cat primary visual cortex. Nat Neurosci, 11(1), 88-94. Kleiner, M., Brainard, D., & Pelli, D. (2007). What's new in Psychtoolbox-3? Perception ECVP abstract, 36, 0-0. Komban, S. J., Alonso, J. M., & Zaidi, Q. (2011). Darks Are Processed Faster Than Lights. The Journal of Neuroscience, 31(23), 8654-8658. doi:10.1523/jneurosci.0504-11.2011 Komban, S. J., Kremkow, J., Jin, J., Wang, Y., Lashgari, R., Li, X., . . . Alonso, J. M. (2014). Neuronal and perceptual differences in the temporal processing of darks and lights. Neuron, 82(1), 224-234. doi:10.1016/j.neuron.2014.02.020 Kremkow, J., Jin, J., Komban, S. J., Wang, Y., Lashgari, R., Li, X., . . . Alonso, J. M. (2014). Neuronal nonlinearity explains greater visual spatial resolution for darks than lights. Proc Natl Acad Sci U S A, 111(8), 3170-3175. doi:10.1073/pnas.1310442111 La Vail, M. M. (1976). Survival of some photoreceptor cells in albino rats following long-term exposure to continuous light. Invest Ophthalmol, 15(1), 64-70. Lippert, M. T., Takagaki, K., Xu, W., Huang, X., & Wu, J. Y. (2007). Methods for voltage-sensitive dye imaging of rat cortical activity with high signal-to-noise ratio. J Neurophysiol, 98(1), 502-512. doi:10.1152/jn.01169.2006 Littell, R. C., Stroup, W. W., Milliken, G. A., Wolfinger, R. D., & Schabenberger, O. (2006). SAS for mixed models: SAS institute. Lu, Z. L., & Sperling, G. (2012). Black-white asymmetry in visual perception. J Vis, 12(10), 8. doi:10.1167/12.10.8 Nichols, Z., Nirenberg, S., & Victor, J. (2013). Interacting linear and nonlinear characteristics produce population coding asymmetries between ON and OFF cells in the retina. J Neurosci, 33(37), 14958-14973. doi:10.1523/JNEUROSCI.1004-13.2013 Niell, C. M., & Stryker, M. P. (2008). Highly selective receptive fields in mouse visual cortex. J Neurosci, 28(30), 7520-7536. doi:10.1523/JNEUROSCI.0623-08.2008 Pandarinath, C., Victor, J. D., & Nirenberg, S. (2010). Symmetry breakdown in the ON and OFF pathways of the retina at night: functional implications. J Neurosci, 30(30), 10006-10014. doi:10.1523/JNEUROSCI.5616-09.2010 Pasupathy, A., & Connor, C. E. (1999). Responses to contour features in macaque area V4. J Neurophysiol, 82(5), 2490-2502. Pelli, D. G. (1997). The VideoToolbox software for visual psychophysics: transforming numbers into movies. Spatial Vision, 10(4), 437-442. doi:doi:10.1163/156856897X00366 Polack, P. O., & Contreras, D. (2012). Long-range parallel processing and local recurrent activity in the visual cortex of the mouse. J Neurosci, 32(32), 11120-11131. doi:10.1523/JNEUROSCI.6304-11.2012 Ratliff, C. P., Borghuis, B. G., Kao, Y.-H., Sterling, P., & Balasubramanian, V. (2010). Retina is structured to process an excess of darkness in natural scenes. Proceedings of the National Academy of Sciences, 107(40), 17368-17373. doi:10.1073/pnas.1005846107 Reid, R. C., & Alonso, J. M. (1995). Specificity of monosynaptic connections from thalamus to visual cortex. Nature, 378(6554), 281-284. doi:10.1038/378281a0 Short, A. D. (1966). Decremental and incremental visual thresholds. J Physiol, 185(3), 646-654. Smith, S. L., & Hausser, M. (2010). Parallel processing of visual space by neighboring neurons in mouse visual cortex. Nat Neurosci, 13(9), 1144-1149. doi:10.1038/nn.2620 Tan, Z., Sun, W., Chen, T.-W., Kim, D., & Ji, N. (2015). Neuronal Representation of Ultraviolet Visual Stimuli in Mouse Primary Visual Cortex. Scientific Reports, 5, 12597. doi:10.1038/srep12597 Wassle, H. (2004). Parallel processing in the mammalian retina. Nat Rev Neurosci, 5(10), 747-757. Xing, D., Yeh, C.-I., Gordon, J., & Shapley, R. M. (2014). Cortical brightness adaptation when darkness and brightness produce different dynamical states in the visual cortex. Proceedings of the National Academy of Sciences, 111(3), 1210-1215. doi:10.1073/pnas.1314690111 Xing, D., Yeh, C. I., & Shapley, R. M. (2010). Generation of black-dominant responses in V1 cortex. J Neurosci, 30(40), 13504-13512. doi:10.1523/JNEUROSCI.2473-10.2010 Yeh, C. I., Xing, D., & Shapley, R. M. (2009). 'Black' responses dominate macaque primary visual cortex v1. J Neurosci, 29(38), 11753-11760. doi:10.1523/JNEUROSCI.1991-09.2009 Zemon, V., Eisner, W., Gordon, J., Grose-Fifer, J., Tenedios, F., & Shoup, H. (1995). Contrast-dependent responses in the human visual system: childhood through adulthood. Int J Neurosci, 80(1-4), 181-201. Zemon, V., Gordon, J., & Welch, J. (1988). Asymmetries in ON and OFF visual pathways of humans revealed using contrast-evoked cortical potentials. Vis Neurosci, 1(1), 145-150. Zhou, H., Friedman, H. S., & von der Heydt, R. (2000). Coding of border ownership in monkey visual cortex. J Neurosci, 20(17), 6594-6611. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51371 | - |
dc.description.abstract | 人類視覺對於負向對比的偵測能力較正向對比要來的好,這種知覺上的對比極性偏好恰好與初級視覺皮質區的神經反應偏好相符-負向對比的視覺刺激能在人類初級視覺皮質區引起較強烈的神經反應。然而近期的神經電位染劑研究卻在小鼠的初級視覺皮質區發現了相反的情況-正向對比的視覺刺激能在小鼠的初級視覺皮質區引起較強烈的螢光變化。神經電位染劑的研究發現暗示了夜行性嚙齒類動物的視覺可能具有和日行性動物相反的對比極性偏好。為了驗證這個假說,我們訓練大鼠針對視覺刺激進行強迫選擇試驗,透過大鼠在強迫選擇試驗中的作答表現,研究大鼠是否也在行為上表現出對對比極性的偏好。我們意外地發現,在低亮度情境下(20 cd/m2),當對比強度增強時,大鼠對負向對比刺激的偵測狀況較正向對比刺激要來得好。這種對比極性偵測能力的不對稱性同樣也能在學習強迫選擇試驗的過程中發現-大鼠在負向對比刺激和酬賞的連結學習速率明顯的比對正向對比刺激和酬賞的連結學習速率要來得快。整體來說,我們的研究發現夜行性嚙齒類動物在光視覺下同樣會表現出較好的負向對比偵測能力,這暗示了夜行性動物的視覺系統在處理對比極性的機制上應該與日行性動物相類似。而神經電位染劑研究中發現由正向對比刺激引起的強烈螢光變化可能反應了該刺激引發強烈的抑制性局部電場電位。 | zh_TW |
dc.description.abstract | Humans can detect negative contrast (black on gray) better and more easily than positive contrast (white on gray). The black-over-white preference in visual perception is accordance with the findings that negative-contrast stimuli can evoke larger neuronal responses than positive-contrast stimuli in primary visual cortex (V1). In contrast, strong white-dominant responses were recently found in mouse V1 with the voltage-sensitive dye imaging (VSDI) technique. Based on these findings, it is possible that nocturnal rodents may prefer positive contrast to negative contrast. Here we used a two-alternative forced choice task to test the preference of contrast polarity in behaving rats (Long Evans). We manipulated contrast polarity (positive or negative contrast), contrast intensity and the mean luminance of the screen (high: 50 cd/m2, low: 20 cd/m2) in our experiments. Surprisingly we found that rats could detect the negative-contrast stimuli better than the positive-contrast stimuli, when the contrast intensity became stronger, in the low luminance condition. This asymmetry in detecting contrast polarity also occurred in the learning progress when rats were learning the contrast detection task. Overall, our behavioral results show that nocturnal rodents can detect negative contrast better than positive contrast in photopic vision. The better sensitivity to negative contrast suggests that the visual system of nocturnal rodents also displays black-over-white bias in visual processing. The white-dominant responses in mouse V1 might reflect the stronger inhibitory signals evoked by the positive-contrast stimuli. | en |
dc.description.provenance | Made available in DSpace on 2021-06-15T13:32:00Z (GMT). No. of bitstreams: 1 ntu-105-R00454001-1.pdf: 5090186 bytes, checksum: 385951afeca0d683e21da2ba90323829 (MD5) Previous issue date: 2016 | en |
dc.description.tableofcontents | CHAPTER 1. INTRODUCTION 1
1.1 POSITIVE AND NEGATIVE CONTRAST IN VISUAL PROCESSING 1 1.2 THE PHENOMENA OF THE BLACK-OVER-WHITE BIAS 2 1.3 PROCESSING OF POSITIVE AND NEGATIVE CONTRAST IN RODENT VISUAL SYSTEM 6 1.4 THE MAIN QUESTION OF THE PRESENT STUDY 10 CHAPTER 2. MATERIAL AND METHOD 12 SUBJECTS. 12 APPARATUS. 12 WATER CONTROL 13 VISUAL STIMULUS 14 TRAINING PROTOCOL. 14 VISUAL CONTRAST DETECTION TASK 18 EXPERIMENTAL DESIGNS 19 STATISTICAL ANALYSIS 21 CHAPTER 3. RESULTS 23 3.1 DETECTION OF NEGATIVE AND POSITIVE CONTRAST 23 3.2 EFFECT OF LUMINANCE ON THE DETECTION OF CONTRAST POLARITY 26 3.3 LEARNING CURVES FOR POSITIVE AND NEGATIVE CONTRAST 32 3.4 METHODOLOGICAL COMPARISON 35 CHAPTER 4. DISCUSSION 39 4.1 THE EFFECT OF LUMINANCE ON CONTRAST DETECTION IN PHOTOPIC VISION 39 4.2 THE NEURAL MECHANISM OF THE “WHITE-OVER-BLACK” BIAS 41 REFERENCES 46 | |
dc.language.iso | en | |
dc.title | 大鼠對負向對比的視覺偏好 | zh_TW |
dc.title | Preference of Negative Contrast in Behaving Rats | en |
dc.type | Thesis | |
dc.date.schoolyear | 104-1 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 梁庚辰(Keng-Chen Liang),裴育晟(Yu-Cheng Pei) | |
dc.subject.keyword | 對比,大鼠,視覺,初級視覺皮質區,視覺系統,行為, | zh_TW |
dc.subject.keyword | contrast,rat,vision,V1,visual system,behavior, | en |
dc.relation.page | 51 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2016-02-02 | |
dc.contributor.author-college | 醫學院 | zh_TW |
dc.contributor.author-dept | 腦與心智科學研究所 | zh_TW |
顯示於系所單位: | 腦與心智科學研究所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
---|---|---|---|
ntu-105-1.pdf 目前未授權公開取用 | 4.97 MB | Adobe PDF |
系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。