星狀聚胺酯高分子與衍生物之合成與性質研究

Chen-Han Yang; 楊振漢

請用此 Handle URI 來引用此文件： http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51168

完整後設資料紀錄

DC 欄位	值	語言
dc.contributor.advisor	邱文英
dc.contributor.author	Chen-Han Yang	en
dc.contributor.author	楊振漢	zh_TW
dc.date.accessioned	2021-06-15T13:26:35Z	-
dc.date.available	2021-04-15
dc.date.copyright	2016-04-15
dc.date.issued	2016
dc.date.submitted	2016-03-17
dc.identifier.citation	1. Z. Wirpsza,〝Polyurethanes chemistry, Technology and Applications〞,Ellis Horwood (1993). 2. G. Oertel,〝Polyurethane Handbook〞, Hanser /Gardner E. Klein, “Affinity Membranes: a 10-Year Review”, J. Membr. Sci., 179, 1 (2000). 3. K. H. Hsieh, C. C. Tsai and D. M. Chang, “Vapor and Gas Permeability of Polyurethane Membranes. Part II. Effecat of Functional Group”, J. Membr. Sci., 56, 279 (1991). 4. M. Pegoraro and A. Penati, “Polyurethane Membrane for Gas Fractionation ”, 5. J. Membr. Sci., 27, 203 (1986). 6. I. H. Musselman and K. J. Balkus, “Poly(3-dodecylthiophene) Membranes for Gas Separations”, J. Membr. Sci, 152, 1 (1998). 7. H. B. Park, C. K. Kim and Y. M. Lee, “Gas Separation Properties of Polysiloxane / Polyether Mixed Soft Segment Urethane Urea Membranes”, J. Membr. Sci, 204, 257 (2002). 8. J. M. Yang, H. T. Lin and W. C. Lai, “Properties of Modified Hydroxyl-Terminated Polybutadiene Based Polyurethane Membrane”, J. Membr. Sci., 208,105 (2002)。 9. S. I. Semenova, S. I. Smirnov and H. Ohya, “Performances of Glassy Polymer Membranes Plasticized by Interacting Penetrants”, J. Membr. Sci., 172, 75 (2000). 10.M. King and Z. Zhang, “Quantitative Analysis of the Surface Morphology and Textile Structure of the Polyurethane VascugraftR Arterial Prostesis Using Image and Statidtical Analyses”, Biomaterials, 15, 621 (1994). 11.R. Guidoin, M. Sigot, M. King and Marie-Francoise Sigot-Luirard, “Biocompatibility of the VascugraftR：Evaluation of a Novel Polyester UrethaneVascular Substitute by an Organotypic Culture Technique”, Biomaterials, 13,281 (1992). 12. J. W. Boretos, W.S. Pierce, Science, 158, 1481-1482 (1967). 13. B. Huang , Y. Marios, R. Roy, M. Julien and R. Guidoin, “Cellular Reaction to the VascugraftR Polyesterurethane Vascular Prosthesis：in vivo Studies in Rats”, Biomaterials, 13, 209 (1992). 14.Y. Marois, R. Guidoin, D. Boyer et al., “In vivo Evaluation of Hydrophobic and Fibrillar Microporous Polyetherurethane Urea Graft”, Biomaterials., 10, 521 (1989). 15.R. W. Hergenrother and S. L. Cooper, “Improved Materials for Blood-Contacting Applications: Blends of Sulphonated and Non-Sulphonated Polyurethanes”,J.Mat. Sci.: Mat. In Med., 3, 313 (1992)。 16.王正一，醫學工程原理與應用，正中書局，台北 (1996). 17.D. Michael, L. Stuart, “Polyurethanes In Medicine”, p.21-p.30 Publications,Inc,(1994). 18.J.W. Boretos, W.S. Pierce, Science, 158, 1481-1482 (1967). 19.M. King, Z. Zhang, Biomaterials, 15, 621 (1994). 20.R. Guidoin, M.F. Sigot-Luirard, Biomaterials, 13, 281 (1992). 21.A. Z. Okkema, S.A. Visser, and S.L. Cooper Lee, J. Biomed. Mater. Res., 25, 1371 (1991). 22.T. G. Grasel, S.L. Cooper, J. Biomed. Mater. Res., 23, 311-338 (1989). 23.賴耿陽,塑膠大全,2001,P82. 24. C. Hepburn, Polyurethane Elastomers, Applied Science Publishers, London and New York (1982). 25. J. H. Saunders and K. C. Frisch, Polyurethanes : Chemistry and Technology Part I. Chemistry, Interscience Publishers, New York (1977). 26. J. H. Saunders and K. C. Frisch, Polyurethanes : Chemistry and Technology Part II. Technology, Interscience Publishers, New York (1977) 27. D. J. David and H. B. Staley, Analytical Chemistry of The Polyurethanes Part III, Wiley-Interscience, New York (1969) 28. R. Iley, H.L. Riley, J. Chem. Soc.; 1948, 1362. 29. S. L. Cooper, A. V. Tobolsky Properties of linear elastomeric polyurethanes. J. Appl. Polym. Sci. 10:1837-1844(1966). 30. J. W. C. Van Bogart, A. Lilaonitkul, S. L. Cooper, Adv. Chem. Ser., 176, 1 (1978) 31. D. S. Huh, S. L. Cooper, “Dynamic Mechanical Properties of Polyurethane Block Polymers”, Polym. Eng. Sci., 11(5), 369(1971). 32. G. M. Estes, S. L. Cooper, A. V. Tobolsky; J. Macromol. Sci., 4(2), 313 (1970). 33. S. Krause, “Microphase Separation in Block Copolymers: Zeroth Approximation”, J. Polym. Sci., 7(A2), 249 (1969). 34. M. J. Flokes, “Processing Structure and Properties of Block Copolymers”, 165 (1976). 35. C. B. Wang, S. L. Cooper, “Morphology and Properties of Segmented Polyether Polyurethaneureas”, Macromolecules, 16, 775 (1983). 36. S. L. Cooper, A. V. Tobolsky., J. Appl. Polym. Sci., 10, 1837 (1966) 37.羅蕙蕙，我國PU樹脂應用市場與技術發展，2003，化學工業研究所應用化學組 38. C. S. Schollenberger, F. D. Stenart, “Advances in urethane Science and Technology“, Ed. K. C. Frisch and S. L. Reegen, 1973, vol 39. Walter Dias Vilar, D. Sc.,”Chemistry and Technology of Polyurethane”, Vilar Consultoria Técnica Ltda. (2002). 40. C. Hepburn, “Polyurethane Eastomers“, Applied Science Publisher, 1982, London and New York. 41. Gnter Oertel, “Polyurethane Handbook“, Hanser Publisher, Munich Vienna, 1985, New York 42. C. S. Schollenberger, F. D. Stenart, “Advances in urethane Science and Technology“, Ed. K. C. Frisch and S. L. Reegen, 1973, vol.2 43.曾文聰, “PU 發泡體的結構與性質”,2001。 44. C. S. Schollenberger, “Polyurethane Technology”, Ed. Bruin, P. F. Interscience Publisher, New York, 1979, p.197 45 J. W. Britain, and P. G. Gemeinhardt, J. of Applied Polymer Science, 4, 207, (1960) 46.A. Ashish,“Structure-Property Relationships Of Flexible Polyurethane Foams” ,2002,P10. 47.C. Creton, Pressure-sensitive adhesives: An introductory course. Mrs Bulletin, 2003. 28(6): p. 434-439. 48.Satas, Handbook of pressure-sensitive adhesive technology. 2 ed. 1989, New York: Van Nostrand Reinhold. 49.楊玉昆, 壓敏膠製品技術手冊. 2004, 北京: 化學工業出版社. 50.薛敬和, 黏著劑全書：材料與技術. 1985, 台北市: 高立圖書有限公司. 51. S. D. Tobing, A. J. Klein, Appl. Polym. Sci. 2001, 79, 2230-2244. 52. S. D. Tobing, A. J. Klein, Appl. Polym. Sci. 2001, 79, 2558-2564. 53. D. Satas, Acrylic Adhesives. In Handbook of Pressure-Sensitive Adhesives, 2nd ed.; D. Satas, Ed.; Van Nostrand Reinhold: New York,1989; Vol. 1 , pp 396-456. 54. L. A. Sobieski, T. J. Tangney, Silicone Pressure Sensitive Adhesives. In Handbook of Pressure Sensitive Adhesives, 2nd ed.; Satas, D., Ed.; Van Nostrand Reinhold: New York, 1989; Vol. 1 , pp 508-526. 55. A. Lindner, B.Lestriez, S. Mariot, C. Creton, T. Maevis, B. Luhmann, R. J. Brummer, Adhes. 2006, 82 (3), 267-310. 56. C. Creton, G. J. Hu, F. Deplace, L. Morgret, K. R. Shull, Macromolecules 2009, 42, 7605-7615. 57.S.B. Lin, et al., Recent advances in silicone pressure-sensitive adhesives. Journal of Adhesion Science and Technology, 2007. 21(7): p. 605-623. 58. E.P. Chang and D. Holguin, Curable optically clear pressure-sensitive adhesives. Journal of Adhesion, 2005. 81(5): p. 495-508. 59. J.F. Watts, , et al., A, in Handbook of Adhesion. 2005, John Wiley & Sons, Ltd. p. 1-58. 60. C. Gay and L. Leibler, On stickiness. Physics Today, 1999. 52(11): p. 48-52. 61. K.N.G. Fuller and D. Tabor, The effect of surface roughness on the adhesion of elastic solids. Proceedings of the Royal Society of London. Series A, Mathematical and Physical Sciences, 1975. 345(1642): p.327-342. 62. M. Rigby , The forces between molecules. 1986, Oxford [Oxfordshire]: Clarendon Press. 63. C.W. Macosko, Adhesives rheology. Adhesives Age, 1977. 20(9): p. 35-37. 64. I. Benedek, Developments in pressure-sensitive products. 2006, Boca Raton, FL: CRC/Taylor & Francis. 65. I. Benedek, Pressure-sensitive formulation. 2000, Boston, Mass.: VSP. 66. H. Lakrout, , P. Sergot, and C. Creton, Direct observation of cavitation and fibrillation in a probe tack experiment on model acrylic Pressure-Sensitive -Adhesives. Journal of Adhesion, 1999. 69(3-4) :p.307-359. 67. Q. Miao, Y. Jin, Y. Dong, Z. Cao, B. Zhang, Surface behavior and micelle morphology of novel nonionic polyurethane bolaform amphiphilic block copolymers, J Polym Res (2010) 17:911 – 921 68. R. Petkewich, 'Liquid Bandages' (2008) Chemical & Engineering News. vol. 86(24) page 61. 69. SC. Davis, WH. Eaglstein, AL. Cazzaniga, PM. Mertz, An octyl-2-cyanoacrylate formulation speeds healing of partial-thickness wounds. Dermatol Surg. 2001; 27:783–8. 70. AJ. Singer, M. Nable, P. Cameau, et al. Evaluation of a new liquid occlusive dressing for excisional wounds. Wound Repair Regen 2003;11:181–7. 71.WH. Eaglestein, TP. Sullivan, PA. Giordano, BM. Miskin, A liquid adhesive bandage for the treatment of minor cuts and abrasions. Dermatol Surg. 2002;28:263–7. 72. O. B. Edgar, R. Hill, J. Polym. Sci., 1952, 8, 1. 73. G. K. Hoeschele, Polym. Eng. Sci., 1974, 14, 848. 74. M. Brown, W. K. Witsiepe, Rubber Age, 1972, 104(3), 35. 75.M. Brown, Ind. Rubber, 1975, 9, 102. 76. D. J. Lyman, D. W. Hill, Trans. Am. Soc. Artif. Ins. Organs, 1972, 18, 19. 77. O. Sangen, K. Aikawa, H. Nakano, Y. Ohno, Kenkyu Hokoku Himeji Koguo Daigaku 1984, 37A, 27 78. Y. Lmai, Jinkouzouki, 1983,12(6), 963. 79. J.H. Saunders, Rubber Chem.Technol.1960,33,1293 80. J.H. Saunders, K.C. Frisch, Polyurethanes, Chemistry and Technology, I. Chemistry, Interscience: New York,1962;Chapter5. 81.D. Klempner and Kurt C. Frisch. Eds,”Polymeric foams”,Hanser Publishers, New York(1991)
dc.identifier.uri	http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/51168	-
dc.description.abstract	聚胺酯(Polyurethane，PU)材料，是一種用途十分廣泛的高分子材料，該材料製備主要是由NCO官能基與含活性氫化合物反應，藉由氫原子移轉之逐步加成聚合而形成的反應。在反應物中選擇不同數目以及不同結構類型的官能基團化合物、以及不同的合成方式，即可製備出性能優異、各式各樣型態成品的聚胺酯材料。例如:發泡體型材料、彈性橡膠、合成纖維、黏著劑以及具有細胞組織的相容性佳所發展的人體組織結構材料…等等。在這項研究中以合成聚氨酯為主要結構的高分子，藉由改變異氰酸酯的種類和多元醇的類型的新穎材料，最終的目的是提供生物醫學材料在黏著、保護、止血與高度生物相容性等方面生醫材料的需求。本文是分為三個部分：part A是合成星狀聚胺酯感壓膠性質與研究。主要是利用polypropylene glycol triol先與IPDI進行聚合形成星狀結構之核心，再提高溫度讓IPDI進行選擇反應連結poly(1,4-butylene adipate) diol而形成最終的星狀聚胺酯高分子。 part B是合成聚胺酯液態繃帶材料性質與研究。要是利用Poly(oxytetramethxlene) glycol(PTMG) diol先與IPDI進行反應形成高分子的主錬段，再加入poly(1,4-butylene adipate) diol提供密著作用力與疏水性；再使用IPDI（trimer）增加高分子的交聯密度提供高分子的硬度。由於輕微的交聯度導致高分子依舊可以溶解於溶劑中，提供使用時可以依照物體的表面起伏而形成包附良好的薄膜。 part C是合成外科手術用之聚胺酯發泡體。使用polypropylene glycol triol 、polyethylene glycol diol 、HDI成為聚胺酯海綿的原材料，利用HDI快速反應與抗黃變能力與PEG的親水性能力與PPG triol提供整體高分子的交聯密度，最後賦予生醫材料聚胺酯泡棉形成親水、具有良好機械性質且不黃變。	zh_TW
dc.description.provenance	Made available in DSpace on 2021-06-15T13:26:35Z (GMT). No. of bitstreams: 1 ntu-105-D00549003-1.pdf: 2741676 bytes, checksum: 5fa4a9c294b041be87301bf025526db9 (MD5) Previous issue date: 2016	en
dc.description.tableofcontents	目錄中文摘要 Ⅱ Abstract IVI 目錄 VI 圖示目錄 X 表格目錄 XII 第一章簡介 1 第二章聚氨酯材料文獻回顧 2 2-1聚胺酯材料與型態 2 2-1-1聚胺酯材料與型態之簡介 2 2-2聚胺酯之合成 6 2-3聚胺酯合成原料之種類 8 2-3-1異氰酸酯 8 2-3-2 聚多元醇 10 2-3-3 鍊延長劑 12 2-3-4 催化劑 14 2-3-5 界面活性劑 16 2-3-6 發泡劑 17 2-3-7 填充物 18 第三章實驗藥品與儀器 20 3-1 實驗藥品 20 3-2 實驗儀器 23 第四章星狀聚胺酯感壓膠之合成與應用 25 4-1 感壓膠之簡介 25 4-2星狀感壓膠之理論基礎 …... 28 4-2-1黏著原理 28 4-2-2感壓膠的黏著特性 30 4-2-2-1 初期黏著力 28 4-2-2-2 黏著力 32 4-2-2-3 內聚力 32 4-3 星狀感壓膠之製備 33 4-4 星狀感壓膠之分析方法 34 4-4-1 傅立葉轉換紅外線光譜 (FT-IR) 34 4-4-2 1H-NMR光譜 34 4-4-3 熱重分析(Thermogravimetric Analysis, TGA) 34 4-4-4 微差掃描卡計(Differential Scanning Calorimetry, DSC) 34 4-4-5 投錨力測試（Tack testing） 4-4-6 剪切強度測試（Shear strength testing） 35 4-4-7 剝離附著力測試（Peel adhesion testing） 35 4-4-8 細胞毒性測試 36 4-5 結果與討論 36 4-5-1傅立葉轉換紅外線光譜(FT-IR)分析 36 4-5-2 1 H-NMR光譜分析 37 4-5-3 熱性質分析 37 4-5-4 投錨力分析 38 4-5-5剪切強度分析 38 4-5-6剝離附著力分析 39 4-5-7細胞毒性分析 39 4-6 結論 40 第五章聚胺酯型液態繃帶之合成與應用 47 5-1液態繃帶之簡介 47 5-2聚胺酯型液態繃帶之合成 47 5-3聚胺酯型液態繃帶之分析方法 48 5-3-1 傅立葉轉換紅外線光譜 (FT-IR) 48 5-3-2 1H-NMR 光譜 48 5-3-3熱重分析(Thermogravimetric Analysis, TGA) 48 5-3-4微差掃描卡計(Differential Scanning Calorimetry, DSC ) 48 5-3-5拉伸測試 (Tensile Strength Test) 49 5-2-6水氣透過率(Water Vapor Transmission Rate) 49 5-3-7細胞毒性測試 49 5-4 結果與討論 51 5-4-1傅立葉轉換紅外線光譜(FT-IR)分析 51 5-4-2 熱性質分析 52 5-4-3 機械性質分析 53 5-4-4 細胞毒性分析 53 5-5 結論 54 第六章鼻腔外科手術用發泡型聚胺酯之合成與應用 61 6-1 發泡型聚胺酯之簡介 61 6-2 發泡反應之理論基礎 61 6-2-1 發泡化學 61 6-2-2 凝膠反應 62 6-2-3 發泡反應 63 6-2-4 聚胺基甲酸酯泡棉形態學 64 6-2-5 發泡物理 65 6-2-5-1 發泡的程序 65 6-2-5-2 氣泡的形成 66 6-2-5-3 氣泡的成長 68 6-2-5-4 氣泡的穩定 68 6-3發泡型聚胺酯之製備 69 6-4發泡型聚胺酯之分析方法 69 6-4-1 熱重分析(Thermogravimetric Analysis, TGA) 6-4-2微差掃描卡計(Differential Scanning Calorimetry, DSC) 70 6-4-3 拉伸測試 (Tensile Strength Test) 70 6-4-4 密度測試（Density test） 71 6-4-5吸水測試(Water Absorption Test) 71 6-4-6細胞毒性測試 71 6-5 結果與討論 72 6-5-1機械性質分析 72 6-5-2熱性質分析 73 6-5-3細胞毒性分析 74 6-6 結論 74 參考文獻 80
dc.language.iso	zh-TW
dc.subject	星狀高分子	zh_TW
dc.subject	聚胺酯	zh_TW
dc.subject	液態繃帶	zh_TW
dc.subject	發泡體	zh_TW
dc.subject	生物醫學材料	zh_TW
dc.subject	聚胺酯	zh_TW
dc.subject	星狀高分子	zh_TW
dc.subject	液態繃帶	zh_TW
dc.subject	發泡體	zh_TW
dc.subject	生物醫學材料	zh_TW
dc.subject	poly(1	en
dc.subject	polyurethane	en
dc.subject	Star-shaped	en
dc.subject	foam	en
dc.subject	Poly (oxytetramethxlene) glycol diol	en
dc.subject	4-butylene adipate) diol	en
dc.subject	poly(1	en
dc.subject	foam	en
dc.subject	Poly (oxytetramethxlene) glycol diol	en
dc.subject	4-butylene adipate) diol	en
dc.subject	Star-shaped	en
dc.subject	polyurethane	en
dc.title	星狀聚胺酯高分子與衍生物之合成與性質研究	zh_TW
dc.title	Synthesis and Characterization of Star-shape Polymer and derivatives	en
dc.type	Thesis
dc.date.schoolyear	104-2
dc.description.degree	博士
dc.contributor.coadvisor	楊台鴻
dc.contributor.oralexamcommittee	鄭如忠,黃琮瑋,王志光
dc.subject.keyword	聚胺酯,星狀高分子,液態繃帶,發泡體,生物醫學材料,	zh_TW
dc.subject.keyword	Star-shaped,polyurethane,poly(1,4-butylene adipate) diol,Poly (oxytetramethxlene) glycol diol,foam,	en
dc.relation.page	87
dc.identifier.doi	10.6342/NTU201600128
dc.rights.note	有償授權
dc.date.accepted	2016-03-18
dc.contributor.author-college	工學院	zh_TW
dc.contributor.author-dept	高分子科學與工程學研究所	zh_TW
顯示於系所單位：	高分子科學與工程學研究所

文件中的檔案：

檔案	大小	格式
ntu-105-1.pdf 未授權公開取用	2.68 MB	Adobe PDF

顯示文件簡單紀錄

系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。