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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 楊燿州(Yao-Joe Yang) | |
| dc.contributor.author | Chia-Ming Chang | en |
| dc.contributor.author | 張家銘 | zh_TW |
| dc.date.accessioned | 2021-06-15T11:54:13Z | - |
| dc.date.available | 2018-10-14 | |
| dc.date.copyright | 2016-10-14 | |
| dc.date.issued | 2016 | |
| dc.date.submitted | 2016-08-11 | |
| dc.identifier.citation | [1] Matthew Ward MBChB FRCA, Jeremy A Langton MD FRCA ILTM “Blood pressure measurement” Oxford Journals, Medicine & Health, BJA: CEACCP Vol. 7, pp. 122-126, 2007.
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Dunn, Gregory Schwartz, Eric Eason, Zhenan Bao, 'Tunable flexible pressure sensors using microstructured elastomer geometries for intuitive electronics,' Advanced Functional Materials, pp.5427-5434, 2014. [27] Changhyun Pang, Gil-Yong Lee, Tae-il Kim, Sang Moon Kim, Hong Nam Kim, Sung-Hoon Ahn and Kahp-Yang Suh, 'A flexible and highly sensitive strain-gauge sensor using reversible interlocking of nanofibers,' Nature materials pp. 795-801, 2012. [28] Chwee-Lin Choong, Mun-Bo Shim, Byoung-Sun Lee, Sanghun Jeon, Dong-Su Ko, Tae-Hyung Kang, Jihyun Bae, Sung Hoon Lee, Kyung-Eun Byun, Jungkyun Im, Yong Jin Jeong, Chan Eon Park, Jong-Jin Park and U-In Chung, 'Highly stretchable resistive pressure sensors using a conductive elastomeric composite on a micropyramid array,' Advanced Materials, pp. 3451-3458, 2014. 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[34] Yingfei Su, Yahui Zhang, Yueming Jin, Yang Yao, Ruifeng Zhang, Yongsheng Jiang and Lisheng Xu, 'The feasibility for dicrotic augmentation index to replace tidal augmentation index,' Information and Automation (ICIA), 2014 IEEE International Conference. [35] Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM and Witteman JC, 'Arterial stiffness and risk of coronary heart disease and stroke the rotterdam study.' Circulation, pp. 657-663, 2006. [36] Stehouwer, C. D. A., R. M. A. Henry, and I. Ferreira. 'Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease.'Diabetologia, pp. 527-539, 2008. [37] Hua Deng, Lin Lin, Mizhi Ji, Shuangmei Zhang, Mingbo Yang and Qiang Fu, 'Progress on the morphological control of conductive network in conductive polymer composites and the use as electroactive multifunctional materials.' Progress in Polymer Science, pp. 627-655, 2014. 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[44] Norden, E, Huang, and Samuel, S, P, Shen “Hilbert-Huang Transform and Its Applications Second Edition” World Scientific Publishing CO. Pte. Ltd ,2005. [45] R. J. Lang, B. Smilowitz, “A Technique for Eliminating Standing Waves and Other Interference Effects in Photoresist,” IEEE Transactions on Sonics and Ultrasonics, vol.27, 1980. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/49876 | - |
| dc.description.abstract | 本研究開發了一高靈敏度的壓力感測器陣列，並將其應用於連續脈波之監測。本研究所提出的感測器由表面具有微結構的高分子材料所組成。感測器將被放置在橈動脈表層的皮膚，並施以一外加壓力固定。根據動脈張力測定法，所測定到的脈波訊號會和血壓值呈現正相關。而藉由陣列化感測器的使用，在量測時，至少會有1至2個感測單元能夠量測到穩定且清晰地脈波訊號，增加感測之效率與使用的便利性。
本研究所提出的壓力感測器陣列由雙層表面具有微結構的導電高分子所組成。其中，導電高分子由PDMS混合多壁奈米碳管所構成，表面的微結構則是利用尼龍濾膜作為模具，將尼龍濾膜表面的的孔隙結構轉印而成。特性量測結果顯示，此元件具有高靈敏度、重複性佳、製程簡單且具可撓性等。本研究亦成功的利用提出的元件量測到脈波訊號，而所量測到的訊號透過Fast Fourier Transform (FFT)與Hilbert Haung Transform (HHT)處理，也能成功的將訊號的漂移與高頻雜訊消除。而在未來的研究中，亦可將此脈波訊號與實際血壓值做轉換，並應用到學術與臨床醫學上使用。 | zh_TW |
| dc.description.abstract | In this work, a highly sensitive piezoresistive tactile sensing array for continuous blood pulse wave monitoring was presented. The polymer-based sensing device was patterned with microdome structures by using nylon membrane filter substrates. The sensing array is placed and pressed on the superficial radial artery. Based on the tonometric method, blood pressure can be estimated from the measured blood pulse wave signals. By using a linear sensing array, at least 1 or 2 sensing channel can easily acquire excellent blood pulse signals without making much effort on aligning the sensing device with the artery.
The proposed sensing array consists of two conductive polymer films which are made by dispersing multi-wall carbon nanotubes (MWCNT) into PDMS matrix patterned with microdome structures by using a membrane filter substrate. Characterization of the proposed sensing elements was conducted. The proposed device features advantages such as high sensitivity, good repeatability, flexibility and simple fabrication process. Experimental results show that continuous blood pulse wave signal can be tracked by the proposed sensing array. The drift and the high frequency noise can be successfully eliminate by applying Fast Fourier Transform (FFT) and Hilbert Haung Transform (HHT).The measured blood pulse wave signal can potentially transformed into real blood pressure value in the future. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T11:54:13Z (GMT). No. of bitstreams: 1 ntu-105-R03522712-1.pdf: 5294954 bytes, checksum: bb509a689272df0c5af720cec685d2f5 (MD5) Previous issue date: 2016 | en |
| dc.description.tableofcontents | 致謝 i
摘要 iii Abstract iv 目錄 v 圖目錄 ix 表目錄 xiv 符號說明 xv 第一章 緒論 1 1.1 前言 1 1.2 文獻回顧 2 1.2.1 侵入式血壓量測 2 1.2.2 非侵入式血壓量測 6 1.2.2.1 聽診法(Auscultatory method) 7 1.2.2.2 振盪法(Oscillometric method) 8 1.2.2.3 恆定容積法(Volume clamp method) 9 1.2.2.4 脈搏波速測定法(Pulse wave velocity method, PWV) 11 1.2.2.5 脈搏傳遞時間法(Pulse transit time method, PTT) 12 1.2.2.6 動脈張力測定法(Tonometry method) 13 1.2.3 壓力感測器 14 1.2.3.1 電容式壓力感測器 15 1.2.3.2 壓阻式壓力感測器 21 1.2.4 具有微結構之壓力感測器 26 1.3 研究動機與目的 32 1.4 論文架構 34 第二章 理論基礎 35 2.1 動脈張力法(Tonometry method)原理 35 2.2 脈波波型分析 40 2.2.1 脈波之特徵點與其生理意義[34] 40 2.2.2 相關生理參數 42 2.3 導電高分子 43 2.3.1 導電粒子 43 2.3.2 高分子基材 44 2.3.3 導電高分子的導電機制 44 2.4 脈搏訊號處理 48 2.4.1 快速傅立葉轉換 49 2.4.2 希爾伯特-黃轉換(Hilbert-Huang Transform, HHT) 51 第三章 元件設計與元件製程 56 3.1 元件設計 56 3.2 工作原理 56 3.3 製作流程 58 3.4 導電高分子之製備 59 3.5 模具製作 62 3.5.1 光罩設計 63 3.5.2 微影製程 64 3.6 圖形化導電高分子製作 69 3.7 元件組裝與封裝 71 3.8 元件製程結果 72 3.8.1 SU-光阻框架與圖形化導電高分子 72 3.8.2 電子顯微鏡(SEM)圖 73 3.8.3 實體元件圖 74 第四章 量測結果與討論 75 4.1 電阻變化率量測 75 4.1.1 量測平台架設 75 4.1.2 量測結果與討論 76 4.2 元件動態響應量測 78 4.2.1 量測平台架設 78 4.2.2 量測結果與討論 79 4.3 元件重複性(repeatability)與耐久性(durability)量測 80 4.4 元件均勻性(Uniformity)量測 81 4.5 元件干擾(crosstalk)現象量測 82 4.6 脈波訊號量測 83 4.6.1 脈波量測設備架設 83 4.7 脈波量測結果與訊號處理 86 4.7.1 量測結果 86 4.7.2 60秒量測資料分析 88 第五章 結論與未來展望 94 5.1 結論 94 5.2 未來展望 95 參考文獻 97 附錄A 103 | |
| dc.language.iso | zh-TW | |
| dc.subject | 連續脈波偵測 | zh_TW |
| dc.subject | 聚二甲基矽氧烷(PDMS) | zh_TW |
| dc.subject | 觸覺感測器 | zh_TW |
| dc.subject | 尼龍濾膜 | zh_TW |
| dc.subject | 動脈張力測定 | zh_TW |
| dc.subject | 導電高分子 | zh_TW |
| dc.subject | 奈米碳管 | zh_TW |
| dc.subject | continuous blood pluse wave measurement | en |
| dc.subject | Carbon nanotubes | en |
| dc.subject | conductive polymer | en |
| dc.subject | nylon membrane filter | en |
| dc.subject | tactile sensor | en |
| dc.subject | polydimethylsiloxane (PDMS) | en |
| dc.subject | tonometric method | en |
| dc.title | 應用於連續脈搏波量測之高靈敏度觸覺感測器陣列開發 | zh_TW |
| dc.title | Highly Sensitive Tunneling Piezoresistive Tactile Sensing Array for Continuous Blood Pulse Wave Monitoring | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 104-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 蘇裕軒,陳國聲(Kuo-Shen Chen),莊嘉揚(Jia-Yang Juang) | |
| dc.subject.keyword | 奈米碳管,導電高分子,尼龍濾膜,觸覺感測器,聚二甲基矽氧烷(PDMS),動脈張力測定,連續脈波偵測, | zh_TW |
| dc.subject.keyword | Carbon nanotubes,conductive polymer,nylon membrane filter,tactile sensor,polydimethylsiloxane (PDMS),tonometric method,continuous blood pluse wave measurement, | en |
| dc.relation.page | 104 | |
| dc.identifier.doi | 10.6342/NTU201602265 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2016-08-11 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 機械工程學研究所 | zh_TW |
| 顯示於系所單位： | 機械工程學系 | |
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