加護病房生理訊號相關性分析

Abstract

庫欣氏反射(也被稱為血管升壓響應、庫欣效果、庫欣現象、庫欣反映)是一種生理神經系統對於增加的顱內壓(ICP)的響應，其結果是會導致三種情況的產生，分別為血壓升高伴隨著心跳速率增高、心跳速率降低、呼吸不規則的三種情況發生，庫欣氏反射通常是見於急性顱腦損傷的終端階段，除此之外，庫欣氏反射也是判別移植的器官是否出現排斥現象的眾多方法之一，一但全部情況都發生了就表明了可能即將會發生腦疝，它是在1901 年第一次由哈維庫欣醫生所發現。 本研究利用了小波轉換，以symmlet 4 當作其母小波，使用了一維離散的小波轉換對訊號進行濾波與增強特徵，先做庫欣氏反應的證實，最後再從趨勢線去抓取像是心跳速率，血壓那些的特徵，期望能從這些比較輕度侵入式的訊號中去預測出病人目前顱內壓的狀態。

Cushing reflex (also known as the vasopressor response, the effect of Cushing, Cushing phenomenon, Cushing reaction) is a biological nervous system for increased intracranial pressure (ICP) in response, and the results will lead to three cases generation, which are high blood pressure with high heart rate, reduce heart rate, and irregular breathing. Cushing's reflex is usually found in the terminal stage of acute brain injury；in addition, Cushing's reflection is one of many ways to determine whether the transplanted organ appears exclusion phenomenon. When a whole case takes place ,it shows that the hernia may be going to happen. It was first described in detail by American neurosurgeon Harvey Cushing in 1901. In this study, the researcher used the wavelet to calculate patient signals. With symmlet 4 as a mother wavelet, the researcher used a one-dimensional discrete wavelet conversion of signal to filter and enhance features. First, the researcher had to confirm Cushing reflex. Finally, the researcher derived the features like heart rate or blood pressure from the trend line and expected it can predict the trend of intracranial pressure state through these less-invasive signals.