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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 林俊彬(Chun-Pin Lin) | |
| dc.contributor.author | Yu-Lun Hsiao | en |
| dc.contributor.author | 蕭煜倫 | zh_TW |
| dc.date.accessioned | 2021-06-15T07:09:01Z | - |
| dc.date.available | 2011-10-03 | |
| dc.date.copyright | 2011-10-03 | |
| dc.date.issued | 2011 | |
| dc.date.submitted | 2011-08-19 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/48697 | - |
| dc.description.abstract | 在近十幾年來，人工植牙廣為流行，已經成為缺牙區域贗復重要的方法之一。為了提供給患者一個良好的咀嚼功能，且能夠快速的接上贗復物使其受力，植體的穩定度扮演了一個重要的角色。所以如何加強植體與骨頭整合的程度，以及提升骨整合的速度，在植體的穩定度上便是個關鍵。因此，植體表面的設計以及處理成為一個重要的問題。
本研究的目的在於評估利用不同方法的表面處理，作用在相同型態的人工牙根，來探討對於骨頭的初步穩定度及骨整合的影響。 其方法是用兩款植體，分別為經酸、鹼、熱(AAH)處理，以及經噴砂後再酸蝕(SLA)處理，來跟Straumann公司的SLA®植體進行比較。利用18隻米格魯犬，拔除其下顎牙齒。每隻狗分別在下顎兩側各植入AAH表面處理植體及SLA表面處理植體各一支，再各植入市售Straumann公司的SLA®一支進行比較。於植體植入前後，進行臨床評估、osstell®共振頻率測量、以及醫學影像紀錄。並於植入後一週、二週、四週、八週、十二週、二十四週等時間點犧牲動物，來進行組織標本觀察。 結果顯示，在存活率方面，實驗組之AAH表面處理植體僅失敗了一支，優於對照組。在共振頻率方面，Straumann公司的SLA®表面處理的植體，在剛植入時的共振頻率測量皆優於實驗組之植體，顯示實驗組植體的初步穩定度尚劣於SLA®植體。但是經一週、二週、四週、八週、十二週、二十四週後觀察，AAH植體其共振頻率測量有優於SLA®趨勢，SLA植體則是略弱於SLA®。而在骨與植體接觸部分，實驗組之AAH表面處理植體表現則是優於對照組。 代表著AAH表面處理植體，在表面處理上具有相當程度的優勢，可以與市售植體相比擬。 | zh_TW |
| dc.description.abstract | Objectives
Over the past few decades, dental implant has become a predictable and widely accepted treatment for fully and partially edentulous patients. In order to provide a better environment for chewing, the stability of implant has play an important role. The term of “osseointegration” which defines as a process in a direct connection between implant and living bone without any soft tissue component interference. Nowadays, the clinical goal of dental implant surgery is the achievement of osseointegration. The higher the degree of osseointegration, the higher the mechanical stability and the successful probability of implants are. It is related to surface design and treatment of implant, so the purpose of this study is to evaluate the different surface treatment on osseointegartion. Material and methods Two different surface treatment implant were used as the experimental group. One is AAH(Acid, Alkaline, Heat) type, the other is SLA (Sand-blasted, Large grit, Acid etched) type. They have the same implant design with different surface treatment. The control group is the Straumann SLA implant. The three type implant have the same width and length which is 3mm x 8mm. We use 18 beagle dogs, each of them were inserted 6 implants, which is included two experimental groups and one control group. The assessments of implants are including clinical evaluation, survival rate, resonance frequency analysis, and photo record. The dogs were sacrificed at the time interval of 1, 2, 4, 8, 12, 24 weeks for further histological analysis. Results In the survival rate, the AAH surface treatment only lose one implant. On the aspect of ISQ, the value of AAH surface treatment arise in the past weeks, even exceed the control group. On the BIC aspect, AAH surface treatment has resided in the leading position. Conclusion The potential for AAH chemical modification of the implant surface to alter biologic events during the osseointegration process and demonstrate success similar to those observed for implants with an SLA surface | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T07:09:01Z (GMT). No. of bitstreams: 1 ntu-100-R96450017-1.pdf: 1488608 bytes, checksum: e292532e90285d9c95c149b7a53ea861 (MD5) Previous issue date: 2011 | en |
| dc.description.tableofcontents | 口試委員會審定書………………………………………………………………i
中文摘要…………………………………………………………………………viii 英文摘要………………………………………………………………………………x 第一章 序論及文獻回顧 1.1 骨整合之概況………………………………………………………………1 1.1.1 植體植入後傷口癒合過程………………………………………………1 1.1.2 骨頭癒合機轉……………………………………………………………2 1.2 人工植體簡介………………………………………………………………2 1.2.1 植體材質介紹……………………………………………………………2 1.2.2 鈦的金屬性質……………………………………………………………3 1.2.3 植體表面的演進…………………………………………………………4 1.2.4 影響植體癒合的因素……………………………………………………4 1.2.5 植體表面處理概要………………………………………………………5 1.2.5.1 鈦噴砂……………………………………………………………6 1.2.5.2 氫氧灰石電漿噴鍍………………………………………………6 1.2.5.3 圓珠狀燒結覆蓋植體……………………………………………7 1.2.5.4 噴砂表面處理……………………………………………………7 1.2.5.5 酸蝕處理…………………………………………………………7 1.2.5.6 陽極氧化處理……………………………………………………7 1.3 本實驗表面處理探討………………………………………………………8 1.3.1 Sand-blasted, Large grit, Acid etched (SLA)………………8 1.3.1.1 SLA簡介…………………………………………………………8 1.3.1.2 SLA表面處理技術………………………………………………8 1.3.1.3 In-vivo data……………………………………………………8 1.3.1.4 In-vitro data……………………………………………………9 1.3.1.5 臨床………………………………………………………………9 1.3.1.6 總結………………………………………………………………9 1.3.2 AAH (acid,alkaline,heat) 酸鹼熱處理…………………………10 1.4 實驗目的……………………………………………………………………10 第二章 材料與方法………………………………………………………………12 2.1 實驗樣本……………………………………………………………………12 2.1.1 研究材料與組…………………………………………………………12 2.1.2 植體選擇………………………………………………………………12 2.1.3 實驗植體種類…………………………………………………………12 2.2.3 實驗設計………………………………………………………………12 2.3 實驗過程及術後照顧………………………………………………………13 2.4 非侵入性觀察………………………………………………………………14 2.4.1 臨床觀察………………………………………………………………14 2.4.2 共振頻率測定…………………………………………………………15 2.5 動物犧牲與標本取得………………………………………………………15 2.6 標本製作與染色……………………………………………………………16 2.7 統計分析……………………………………………………………………16 第三章 結果………………………………………………………………………17 3.1 存活率………………………………………………………………………17 3.1.1 一周存活率……………………………………………………………17 3.1.2二周存活率……………………………………………………………17 3.1.3四周存活率……………………………………………………………17 3.1.4八周存活率……………………………………………………………18 3.1.5十二周存活率…………………………………………………………18 3.1.6 二十四周存活率………………………………………………………18 3.1.7整體存活率……………………………………………………………18 3.2 植體穩定商數(ISQ)………………………………………………………19 3.2.1初期穩定度……………………………………………………………19 3.2.2二周穩定度……………………………………………………………19 3.2.3四周穩定度……………………………………………………………19 3.2.4八周穩定度……………………………………………………………19 3.2.5十二周穩定度…………………………………………………………20 3.2.6二十四周穩定度………………………………………………………20 3.3骨與植體表面接觸百分比(BIC)…………………………………………20 3.3.1 一周……………………………………………………………………20 3.3.2 二周……………………………………………………………………21 3.3.3 四周……………………………………………………………………21 3.3.4 八周……………………………………………………………………21 3.3.5 十二周…………………………………………………………………21 3.3.6二十四周………………………………………………………………22 3.4 統計資料…………………………………………………………………22 第四章 討論…………………………………………………………………………23 4.1 實驗動物之探討 ……………………………………………………………23 4.1.1 狗(dogs)………………………………………………………………23 4.1.2 豬(pigs)………………………………………………………………24 4.1.3 羊(sheeps/goats)……………………………………………………24 4.1.4 兔子(rabbits)…………………………………………………………25 4.1.5 結論……………………………………………………………………25 4.2存活率之探討…………………………………………………………………………254.3 植體穩定商數之探討………………………………………………………26 4.3.1 初期穩定度……………………………………………………………27 4.3.2 二周及四周穩定度……………………………………………………27 4.3.3 八周穩定度……………………………………………………………27 4.3.4 十二周及二十四周穩定度……………………………………………28 4.3.5 整體穩定度討論………………………………………………………28 4.4 骨與植體表面接觸百分比之探討…………………………………………29 4.4.1 一周……………………………………………………………………29 4.4.2 二周、四周、八周………………………………………………………29 4.4.3 十二周、二十四周………………………………………………………29 4.4.4 BIC值整體討論…………………………………………………………30 4.5實驗設計與方法之探討……………………………………………………30 第五章 結論………………………………………………………………………32 參考文獻……………………………………………………………………33 附錄…………………………………………………………………………………46 | |
| dc.language.iso | zh-TW | |
| dc.subject | 表面處理 | zh_TW |
| dc.subject | SLA | zh_TW |
| dc.subject | 骨整合 | zh_TW |
| dc.subject | AAH | zh_TW |
| dc.subject | surface treatment | en |
| dc.subject | osseointegration | en |
| dc.subject | AAH | en |
| dc.subject | SLA | en |
| dc.title | 酸鹼熱複合表面處理對植體骨整合之影響:動物實驗 | zh_TW |
| dc.title | The effect of AAH surface treatment on dental implant: an animal study | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 99-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 陳文斌(Weng-Pin Chen),章浩宏(Hao-Hueng Chang) | |
| dc.subject.keyword | 骨整合,表面處理,SLA,AAH, | zh_TW |
| dc.subject.keyword | osseointegration,surface treatment,AAH,SLA, | en |
| dc.relation.page | 61 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2011-08-19 | |
| dc.contributor.author-college | 牙醫專業學院 | zh_TW |
| dc.contributor.author-dept | 口腔生物科學研究所 | zh_TW |
| 顯示於系所單位： | 口腔生物科學研究所 | |
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