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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46181
標題: | 利用穿透後末端膨脹法合成車輪烷 Using a Threading-Followed-by-Swelling Approach to Synthesize [2]Rotaxanes |
作者: | Jia-Ling Ko 柯嘉玲 |
指導教授: | 邱勝賢 |
關鍵字: | 車輪烷, rotaxane, |
出版年 : | 2010 |
學位: | 博士 |
摘要: | We have developed a “threading-followed-by-swelling” protocol to synthesize [2]rotaxanes efficiently and atom-economically. Our protocol employs cis-1-[(Z)-alk-1′-enyl]-2-vinylcyclopropane units as the termini of the threadlike component; these end groups are converted into more-sizable cycloheptadiene motifs, which function as stopper units, through Cope rearrangements at elevated temperature. We used this approach to synthesize [2]rotaxanes in good yield from [2]pseudorotaxanes featuring either one or two swellable termini to interlock three different types of macrocycle. The chiral centers created by the swelling process were “erased” by hydrogenating the cycloheptadiene termini into the corresponding cycloheptane units, affording achiral molecular [2]rotaxanes as the only final products. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46181 |
全文授權: | 有償授權 |
顯示於系所單位: | 化學系 |
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