Please use this identifier to cite or link to this item:
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/45335Full metadata record
| ???org.dspace.app.webui.jsptag.ItemTag.dcfield??? | Value | Language |
|---|---|---|
| dc.contributor.advisor | 陳立仁(Li-Jen Chen) | |
| dc.contributor.author | Ya-Hui Hsu | en |
| dc.contributor.author | 許雅惠 | zh_TW |
| dc.date.accessioned | 2021-06-15T04:14:50Z | - |
| dc.date.available | 2012-01-21 | |
| dc.date.copyright | 2010-01-21 | |
| dc.date.issued | 2010 | |
| dc.date.submitted | 2010-01-14 | |
| dc.identifier.citation | Alexandridis, P. and T. A. Hatton (1995). Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block-copolymer surfactants in aqueous-solutions and at interfaces - thermodynamics, structure, dynamics, and modeling. Colloids and Surfaces a-Physicochemical and Engineering Aspects 96(1-2): 1-46.
Alexandridis, P., J. F. Holzwarth and T. A. Hatton (1994). Micellization of poly(ethylene oxdie)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymers in aqueous solutions - thermodynamics of copolymer association. Macromolecules 27(9): 2414-2425. Armstrong, J., B. Chowdhry, J. Mitchell, A. Beezer and S. Leharne (1996). Effect of cosolvents and cosolutes upon aggregation transitions in aqueous solutions of the poloxamer F87 (Poloxamer p237): A high sensitivity differential scanning calorimetry study. Journal of Physical Chemistry 100(5): 1738-1745. Armstrong, J. K., B. Z. Chowdhry, M. J. Snowden and S. A. Leharne (1998). Effect of sodium chloride upon micellization and phase separation transitions in aqueous solutions of triblock copolymers: A high-sensitivity differential scanning calorimetry study. Langmuir 14(8): 2004-2010. Bakshi, M. S. and S. Sachar (2006). Influence of hydrophobicity on the mixed micelles of Pluronic F127 and P103 plus cationic surfactant mixtures. Colloids and Surfaces a-Physicochemical and Engineering Aspects 276(1-3): 146-154. Batsberg, W., S. Ndoni, C. Trandum and S. Hvidt (2004). Effects of poloxamer inhomogeneities on micellization in water. Macromolecules 37(8): 2965-2971. Bharatiya, B., V. K. Aswal, P. A. Hassan and P. Bahadur (2008). Influence of a hydrophobic diol on the micellar transitions of Pluronic P85 in aqueous solution. Journal of Colloid and Interface Science 320(2): 452-459. Bharatiya, B., C. Guo, J. H. Ma, P. A. Hassan and P. Bahadur (2007). Aggregation and clouding behavior of aqueous solution of EO-PO block copolymer in presence of n-alkanols. European Polymer Journal 43(5): 1883-1891. Booth, C. and D. Attwood (2000). Effects of block architecture and composition on the association properties of poly(oxyalkylene) copolymers in aqueous solution. Macromolecular Rapid Communications 21(9): 501-527. Booth, C., D. Attwood and C. Price (2006). Self-association of block copoly(oxyalkylene)s in aqueous solution. Effects of composition, block length and block architecture. Physical Chemistry Chemical Physics 8(31): 3612-3622. Chaibundit, C., N. Ricardo, F. Costa, M. G. P. Wong, D. Hermida-Merino, J. Rodriguez-Perez, I. W. Hamley, S. G. Yeates and C. Booth (2008). Effect of Ethanol on the Micellization and Gelation of Pluronic P123. Langmuir 24(21): 12260-12266. Chen, L. J., S. Y. Lin and C. C. Huang (1998). Effect of hydrophobic chain length of surfactants on enthalpy-entropy compensation of micellization. Journal of Physical Chemistry B 102(22): 4350-4356. Chen, L. J., Y. H. Shen and P. J. Li (2004). Heat capacity changes accompanying micelle formation upon burial of hydrophobic tail of nonionic surfactants. Journal of Physical Chemistry B 108(50): 19096-19098. Cheng, Y. D. and C. Jolicoeur (1995). Cosolvent effects on thermally-induced transitions of a block-copolymer - poly(ethylene oxide)-poly(propylene oxide) in aqueous-solutions. Macromolecules 28(8): 2665-2672. Cole, M. L. and T. L. Whateley (1995). Preparation of stable mutiple W/O/W emulsions using Pluronic (Poloxamer) poly(acrylic acid) complexes. Journal of Colloid and Interface Science 175(2): 281-288. Croy, S. R. and G. S. Kwon (2004). The effects of Pluronic block copolymers on the aggregation state of nystatin. Journal of Controlled Release 95(2): 161-171. Desai, P. R., N. J. Jain and P. Bahadur (2002). Anomalous clouding behavior of an ethylene oxide-propylene oxide block copolymer in aqueous solution. Colloids and Surfaces a-Physicochemical and Engineering Aspects 197(1-3): 19-26. Ding, Y. H., Y. Wang and R. Guo (2003). Diffusion coefficients and structure properties in the pluronic F127/n-C4H9OH/H2O system. Journal of Dispersion Science and Technology 24(5): 673-681. Du, F., Y. Liang, B. R. Zhou, Y. Xia, M. C. Kilhoffer and J. Haiech (2004). Unfolding of creatine kinase induced by acid studied by isothermal titration calorimetry and fluorescence spectroscopy. Thermochimica Acta 416: 17-21. Fernandez, V. V. A., J. F. A. Soltero, J. E. Puig and Y. Rharbi (2009). Temporal evolution of the size distribution during exchange kinetics of Pluronic P103 at low temperatures. Journal of Physical Chemistry B 113(10): 3015-3023. Guo, C., H. Z. Liu and J. Y. Chen (2000). A Fourier transform infrared study on water-induced reverse micelle formation of block copoly(oxyethylene-oxypropylene-oxyethylene) in organic solvent. Colloids and Surfaces a-Physicochemical and Engineering Aspects 175(1-2): 193-202. Hecht, E. and H. Hoffmann (1995). Kinetic and calorimetric investigations on micelle formation of block-copolymers of the poloxamer type. Colloids and Surfaces a-Physicochemical and Engineering Aspects 96(1-2): 181-197. Hildebrand, A., P. Garidel, R. Neubert and A. Blume (2004). Thermodynamics of demicellization of mixed micelles composed of sodium oleate and bile salts. Langmuir 20(2): 320-328. Hvidt, S. and W. Batsberg (2007). Characterization and micellization of a poloxamer block copolymer. International Journal of Polymer Analysis and Characterization 12(1): 13-22. Hvidt, S., E. B. Jorgensen, W. Brown and K. Schillen (1994). Micellization and gelation of aqueous-solutions of a triblock copolymer studied by rheological techniques and scanning calorimetry. Journal of Physical Chemistry 98(47): 12320-12328. Hvidt, S., C. Trandum and W. Batsberg (2002). Effects of poloxamer polydispersity on micellization in water. Journal of Colloid and Interface Science 250(1): 243-250. Kwon, K. W., M. J. Parl, J. Hwang and K. Char (2001). Effects of alcohol addition on gelation in aqueous solution of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer. Polymer Journal 33(5): 404-410. Letchford, K. and H. Burt (2007). A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes. European Journal of Pharmaceutics and Biopharmaceutics 65(3): 259-269. Li, X. F., S. D. Wettig and R. E. Verrall (2004). Interactions between 12-EOx-12 gemini Surfactants and pluronic ABA block copolymers (F108 and P103) studied by isothermal titration calorimetry. Langmuir 20(3): 579-586. Liang, X. F., C. Guo, J. H. Ma, J. Wang, S. Chen and H. Z. Liu (2007). Temperature-dependent aggregation and disaggregation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer in aqueous solution. Journal of Physical Chemistry B 111(46): 13217-13220. Liang, X. M., G. Z. Mao and K. Y. S. Ng (2005). Effect of chain lengths of PEO-PPO-PEO on small unilamellar liposome morphology and stability: an AFM investigation. Journal of Colloid and Interface Science 285(1): 360-372. Linse, P. (1994). Micellization of poly(ethylene oxide)-poly(propylene oxide) block-copolymers in aqueous-solution -effect of polymer polydispersity. Macromolecules 27(22): 6404-6417. Ma, J. H., Y. Wang, C. Guo, H. Z. Liu, Y. L. Tang and P. Bahadur (2007). Oil-induced aggregation of block copolymer in aqueous solution. Journal of Physical Chemistry B 111(38): 11140-11148. Mata, J. P., P. R. Majhi, O. Kubota, A. Khanal, K. Nakashima and P. Bahadur (2008). Effect of phenol on the aggregation characteristics of an ethylene oxide-propylene oxide triblock copolymer P65 in aqueous solution. Journal of Colloid and Interface Science 320(1): 275-282. Meilleur, L., A. Hardy and F. Quirion (1996). Probing the structure of pluronic PEO-PPO-PEO block copolymer solutions with their apparent volume and heat capacity. Langmuir 12(20): 4697-4703. Mortensen, K., W. Batsberg and S. Hvidt (2008). Effects of PEO-PPO diblock impurities on the cubic structure of aqueous PEO-PPO-PEO pluronics micelles: fcc and bcc ordered structures in F127. Macromolecules 41(5): 1720-1727. Myers, D. (1999). Surface, Interfaces, and Colloids: Principles and Applications. Nixon, S. K., S. Hvidt and C. Booth (2004). Micellization of block copolymer P94 in aqueous solution. Journal of Colloid and Interface Science 280(1): 219-223. Pasch, H. (1996). Liquid chromatography at the critical point of adsorption - A new technique for polymer characterization. Macromolecular Symposia 110: 107-120. Patel, K., P. Bahadur, C. Guo, J. H. Ma, H. Z. Liu, Y. Yamashita, A. Khanal and K. Nakashima (2007). Salt induced micellization of very hydrophilic PEO-PPO-PEO block copolymers in aqueous solutions. European Polymer Journal 43(5): 1699-1708. Paterson, I., J. Armstrong, B. Chowdhry and S. Leharne (1997). Thermodynamic model fitting of the calorimetric output obtained for aqueous solutions of oxyethylene-oxypropylene-oxyethylene triblock copolymers. Langmuir 13(8): 2219-2226. Senkow, S., S. K. Mehta, G. Douheret, A. H. Roux and G. Roux-Desgranges (2002). Aqueous solutions of some amphiphilic poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymers. A thermodynamic study over a wide concentration range at temperatures between 288.15 and 328.15 K. Physical Chemistry Chemical Physics 4(18): 4472-4480. Su, Y. L., X. F. Wei and H. Z. Liu (2003). Influence of 1-pentanol on the micellization of poly(ethylene oxide)-polypropylene oxide)-polyethylene oxide) block copolymers in aqueous solutions. Langmuir 19(7): 2995-3000. Takahashi, K. and J. M. Sturtevant (1981). Thermal-denaturation of streptomyces subtilisin inhibitor, subtilisin BPN', and the inhibitor-subtilisin complex. Biochemistry 20(21): 6185-6190. Trathnigg, B. (2005). Characterization of amphiphilic polymers: Independent analysis of blocks in poloxamers by liquid chromatography under critical conditions. Polymer 46(22): 9211-9223. Trathnigg, B. and A. Gorbunov (2006). Characterization of EO-PO block copolymers by liquid chromatography under critical conditions. Macromolecular Symposia 237: 18-27. Tsui, H. W., Y. H. Hsu, J. H. Wang and L. J. Chen (2008). Novel Behavior of Heat of Micellization of Pluronics F68 and F88 in Aqueous Solutions. Langmuir 24(24): 13858-13862. Varade, D., R. Sharma, V. K. Aswal, P. S. Goyal and P. Bahadur (2004). Effect of hydrotropes on the solution behavior of PEO/PPO/PEO block copolymer L62 in aqueous solutions. European Polymer Journal 40(11): 2457-2464. Varshney, M., T. E. Morey, D. O. Shah, J. A. Flint, B. M. Moudgil, C. N. Seubert and D. M. Dennis (2004). Pluronic microemulsions as nanoreservoirs for extraction of bupivacaine from normal saline. Journal of the American Chemical Society 126(16): 5108-5112. Wang, Q., G.-E. Yu, Y. Deng, C. Price and C. Booth (1993). Eluent Gel Permeation Chromatography: Application to the Association of Block Copolymer F127 in Aqueous Solution. European Polymer Journal 29(5): 665-669. Wanka, G. (1994). Phase-diagrams and aggregation behavior of poly(oxyethylene)-poly(oxypropylene)-poly(oxyethylene) triblock copolymers in aqueous-solutions. Macromolecules 27(15): 4145-4159. Yu, G. E., H. Altinok, S. K. Nixon, C. Booth, P. Alexandridis and T. A. Hatton (1997). Self-association properties of oxyethylene/oxypropylene/oxyethylene triblock copolymer F88. European Polymer Journal 33(5): 673-677. Yu, G. E., Y. L. Deng, S. Dalton, Q. G. Wang, D. Attwood, C. Price and C. Booth (1992). Micellization and gelation of triblock copoly(oxyethlene oxypropylene oxyethylene), F127. Journal of the Chemical Society-Faraday Transactions 88(17): 2537-2544. Zhang, S. H., N. Li, L. Q. Zheng, X. W. Li, Y. A. Gao and L. Yu (2008). Aggregation behavior of pluronic triblock copolymer in 1-butyl-3-methylimidazolium type ionic liquids. Journal of Physical Chemistry B 112(33): 10228-10233. 崔宏瑋 (2007), 碩士學位論文, 聚氧乙烯-聚氧丙烯-聚氧乙烯聚合物形成微胞之焓變化研究, 國立台灣大學化學工程學研究所 | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/45335 | - |
| dc.description.abstract | 本研究主要分為兩部分，第一部分為探討添加不同碳鏈長度之直碳鏈醇類及不同濃度之直碳鏈醇類對Pluronic F88微胞化過程及相分離的影響，第二部分為探討降低合成時所產生的分散性(polydispersity) 對Pluronic F108微胞化過程及相分離的影響。
在第一部分中，我們利用高感度掃描式微分熱卡計觀察添加不同碳鏈長度及不同濃度之直碳鏈醇類對Pluronic F88微胞化過程及相分離的影響。添加乙醇會使臨界微胞溫度(critical micelle temperature, CMT)上升，使微胞化焓(heat of micellization)下降，使雲點(cloud point)上升；添加丁醇會使CMT下降，使微胞化焓上升，使雲點下降；添加丙醇會使CMT下降，使微胞化焓下降，使雲點在不同Pluronic濃度時略為上升或下降。隨著添加醇類的量上升，所觀察到的上述效應越為明顯。 在第二部分中，我們利用動態光散射觀察不同濃度的Pluronic F108在不同溫度下的粒徑分布情形，發現低濃度與高濃度的樣品在形成微胞前均會產生大型聚集，但存在於高濃度的樣品中之大型聚集會隨溫度上升而逐漸分解而重新排列至微胞中，而存在於低濃度樣品內之大型聚集則較難分解，因而重新排入微胞內的比例則較低。另外利用高壓液相層析法根據Pluronic F108的分子量分佈進行分離。進行分離前，當CMT小於32 oC時，微胞化焓會隨CMT上升而上升；當CMT大於32 oC時，微胞化焓會隨CMT上升而下降。純化後之產物其微胞化焓與CMT成線性關係並隨CMT上升而下降。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2021-06-15T04:14:50Z (GMT). No. of bitstreams: 1 ntu-99-R96524091-1.pdf: 5990677 bytes, checksum: e580ae3d4080a336c09b099e8a9e9480 (MD5) Previous issue date: 2010 | en |
| dc.description.tableofcontents | 誌謝 I
摘要 II Abstract III 目錄 V 表目錄 VIII 圖目錄 IX 第一章 緒論 1 1-1 界面活性劑簡介及分類 1 1-2 Pluronics簡介 2 1-3 實驗動機 2 第二章 文獻回顧 7 2-1 Pluronics微胞化機制 7 2-1.1 熵驅動反應(entropy-driven process) 8 2-2 模擬微胞化機制之熱力學模型 8 2-2.1 焓熵補償現象(enthalpy-entropy compensation) 9 2-3 以高感度微分掃描熱卡計量測微胞化焓 10 2-4 添加醇類的效應 11 2-5 分散性(Polydispersity) 13 2-5.1 以沖提液凝膠滲透層析法探討分散性的影響 14 2-6 臨界液相層析法(Liquid chromatography under critical conditions, LCCC) 16 第三章 實驗設備及方法 34 3-1 實驗設備 34 3-2 實驗藥品 35 3-3 儀器量測原理 36 3-3.1 微分掃描式熱卡計 36 3-3.2 高壓液相層析法 36 3-4 實驗方法 37 3-4.1 實驗用具清洗、配製 37 3-4.2 微分掃描式熱卡計 38 3-4.3 沖提液凝膠液相層析法 39 3-4.4 高壓液相層析法 40 第四章 研究結果及討論 45 4-1 高感度微分掃描式熱卡計數據處理方法 45 4-1.1 臨界微胞溫度的判定 45 4-1.2 決定DSC數據處理之基線 45 4-1.3 HSDSC吸/放熱曲線之校正 46 4-2 添加醇類之結果討論 47 4-2.1 不同碳鏈長度之直碳鏈醇類對Pluronic F88微胞化過程的影響 47 4-2.2 不同濃度之直碳鏈醇類對Pluronic F88微胞化過程的影響 50 4-2.3 添加醇類對焓熵補償效應的影響 51 4-2.4 添加醇類對雲點(cloud point)的影響 51 4-3 以動態光散射觀察Pluronics微胞化機制 52 4-4 Polydispersity對Pluronic微胞化過程的影響 54 4-4.1 以沖提液凝膠滲透層析法(EGPC)探討polydispersity對Pluronic微胞化過程的影響 54 4-4.2 降低Polydispersity對微胞化過程的影響 55 第五章 結論 90 參考文獻 92 附錄 97 | |
| dc.language.iso | zh-TW | |
| dc.subject | 分散性 | zh_TW |
| dc.subject | 微胞 | zh_TW |
| dc.subject | 醇類 | zh_TW |
| dc.subject | alcohols | en |
| dc.subject | micelles | en |
| dc.subject | polydispersity | en |
| dc.title | 聚氧乙烯-聚氧丙烯-聚氧乙烯聚合物微胞化之熱力學性質探討 | zh_TW |
| dc.title | A Study on the Thermodynamic Properties of the Micellization Process of Pluronics | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 98-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 林析右(Shi-Yow Lin),蔡瑞瑩(Ruey-Ying Tsai) | |
| dc.subject.keyword | 微胞,醇類,分散性, | zh_TW |
| dc.subject.keyword | micelles,alcohols,polydispersity, | en |
| dc.relation.page | 116 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2010-01-15 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 化學工程學研究所 | zh_TW |
| Appears in Collections: | 化學工程學系 | |
Files in This Item:
| File | Size | Format | |
|---|---|---|---|
| ntu-99-1.pdf Restricted Access | 5.85 MB | Adobe PDF |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.