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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 陳立仁(Li-Jen Chen) | |
| dc.contributor.author | Ya-Hui Hsu | en |
| dc.contributor.author | 許雅惠 | zh_TW |
| dc.date.accessioned | 2021-06-15T04:14:50Z | - |
| dc.date.available | 2012-01-21 | |
| dc.date.copyright | 2010-01-21 | |
| dc.date.issued | 2010 | |
| dc.date.submitted | 2010-01-14 | |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/45335 | - |
| dc.description.abstract | 本研究主要分為兩部分，第一部分為探討添加不同碳鏈長度之直碳鏈醇類及不同濃度之直碳鏈醇類對Pluronic F88微胞化過程及相分離的影響，第二部分為探討降低合成時所產生的分散性(polydispersity) 對Pluronic F108微胞化過程及相分離的影響。
在第一部分中，我們利用高感度掃描式微分熱卡計觀察添加不同碳鏈長度及不同濃度之直碳鏈醇類對Pluronic F88微胞化過程及相分離的影響。添加乙醇會使臨界微胞溫度(critical micelle temperature, CMT)上升，使微胞化焓(heat of micellization)下降，使雲點(cloud point)上升；添加丁醇會使CMT下降，使微胞化焓上升，使雲點下降；添加丙醇會使CMT下降，使微胞化焓下降，使雲點在不同Pluronic濃度時略為上升或下降。隨著添加醇類的量上升，所觀察到的上述效應越為明顯。 在第二部分中，我們利用動態光散射觀察不同濃度的Pluronic F108在不同溫度下的粒徑分布情形，發現低濃度與高濃度的樣品在形成微胞前均會產生大型聚集，但存在於高濃度的樣品中之大型聚集會隨溫度上升而逐漸分解而重新排列至微胞中，而存在於低濃度樣品內之大型聚集則較難分解，因而重新排入微胞內的比例則較低。另外利用高壓液相層析法根據Pluronic F108的分子量分佈進行分離。進行分離前，當CMT小於32 oC時，微胞化焓會隨CMT上升而上升；當CMT大於32 oC時，微胞化焓會隨CMT上升而下降。純化後之產物其微胞化焓與CMT成線性關係並隨CMT上升而下降。 | zh_TW |
| dc.description.provenance | Made available in DSpace on 2021-06-15T04:14:50Z (GMT). No. of bitstreams: 1 ntu-99-R96524091-1.pdf: 5990677 bytes, checksum: e580ae3d4080a336c09b099e8a9e9480 (MD5) Previous issue date: 2010 | en |
| dc.description.tableofcontents | 誌謝 I
摘要 II Abstract III 目錄 V 表目錄 VIII 圖目錄 IX 第一章 緒論 1 1-1 界面活性劑簡介及分類 1 1-2 Pluronics簡介 2 1-3 實驗動機 2 第二章 文獻回顧 7 2-1 Pluronics微胞化機制 7 2-1.1 熵驅動反應(entropy-driven process) 8 2-2 模擬微胞化機制之熱力學模型 8 2-2.1 焓熵補償現象(enthalpy-entropy compensation) 9 2-3 以高感度微分掃描熱卡計量測微胞化焓 10 2-4 添加醇類的效應 11 2-5 分散性(Polydispersity) 13 2-5.1 以沖提液凝膠滲透層析法探討分散性的影響 14 2-6 臨界液相層析法(Liquid chromatography under critical conditions, LCCC) 16 第三章 實驗設備及方法 34 3-1 實驗設備 34 3-2 實驗藥品 35 3-3 儀器量測原理 36 3-3.1 微分掃描式熱卡計 36 3-3.2 高壓液相層析法 36 3-4 實驗方法 37 3-4.1 實驗用具清洗、配製 37 3-4.2 微分掃描式熱卡計 38 3-4.3 沖提液凝膠液相層析法 39 3-4.4 高壓液相層析法 40 第四章 研究結果及討論 45 4-1 高感度微分掃描式熱卡計數據處理方法 45 4-1.1 臨界微胞溫度的判定 45 4-1.2 決定DSC數據處理之基線 45 4-1.3 HSDSC吸/放熱曲線之校正 46 4-2 添加醇類之結果討論 47 4-2.1 不同碳鏈長度之直碳鏈醇類對Pluronic F88微胞化過程的影響 47 4-2.2 不同濃度之直碳鏈醇類對Pluronic F88微胞化過程的影響 50 4-2.3 添加醇類對焓熵補償效應的影響 51 4-2.4 添加醇類對雲點(cloud point)的影響 51 4-3 以動態光散射觀察Pluronics微胞化機制 52 4-4 Polydispersity對Pluronic微胞化過程的影響 54 4-4.1 以沖提液凝膠滲透層析法(EGPC)探討polydispersity對Pluronic微胞化過程的影響 54 4-4.2 降低Polydispersity對微胞化過程的影響 55 第五章 結論 90 參考文獻 92 附錄 97 | |
| dc.language.iso | zh-TW | |
| dc.subject | 分散性 | zh_TW |
| dc.subject | 微胞 | zh_TW |
| dc.subject | 醇類 | zh_TW |
| dc.subject | alcohols | en |
| dc.subject | micelles | en |
| dc.subject | polydispersity | en |
| dc.title | 聚氧乙烯-聚氧丙烯-聚氧乙烯聚合物微胞化之熱力學性質探討 | zh_TW |
| dc.title | A Study on the Thermodynamic Properties of the Micellization Process of Pluronics | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 98-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 林析右(Shi-Yow Lin),蔡瑞瑩(Ruey-Ying Tsai) | |
| dc.subject.keyword | 微胞,醇類,分散性, | zh_TW |
| dc.subject.keyword | micelles,alcohols,polydispersity, | en |
| dc.relation.page | 116 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2010-01-15 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 化學工程學研究所 | zh_TW |
| 顯示於系所單位： | 化學工程學系 | |
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