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  1. NTU Theses and Dissertations Repository
  2. 醫學院
  3. 牙醫專業學院
  4. 臨床牙醫學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/44804
完整後設資料紀錄
DC 欄位值語言
dc.contributor.advisor林俊彬(Chun-Pin Lin)
dc.contributor.authorYueh-Chiao Chuangen
dc.contributor.author莊岳樵zh_TW
dc.date.accessioned2021-06-15T03:55:19Z-
dc.date.available2013-09-09
dc.date.copyright2010-09-09
dc.date.issued2010
dc.date.submitted2010-06-25
dc.identifier.citation1.Barbour ME, Parker DM, Allen GC, Jandt KD (2003). Human enamel dissolution in citric acid as a function of pH in the range 2.30< or =pH< or =6.30--a nanoindentation study. Eur J Oral Sci Jun;111(3):258-62.
2.Barbour ME, Rees JS(2004). The laboratory assessment of enamel erosion: a review. J Dent Nov;32(8):591-60.
3.Barbour ME, Parker DM, Allen GC, Jandt KD (2005). Human enamel erosion in constant composition citric acid solutions as a function of degree of saturation with respect to hydroxyapatite. J Oral Rehabil Jan;32(1):16-21.
4.Birkhed D (1984). Sugar content, acidity and effect on plaque pH of fruit juices, fruit drinks, carbonated beverages and sport drinks. Caries Research 18:120–7.
5.Centerwall BS, Armstrong CW, Funkhouser LS, Elzay RP (1986). Erosion of dental enamel among competitive swimmers at a gas-chlorinated swimming pool.Am J Epidemiol Apr;123(4):641-7.
6.Colin-Jones DG (1996). Gastro-oeosphageal reflux disease. Prescribers’ Journal 36:66.
7.Dorozhkin SV (1997). Surface reactions of apatite dissolution. J Colloid Interface Sci 191: 489–497.
8.Driessens FCM, in: H.M. Myers (Ed.) (1982). Monographs in Oral Science, Karger, Basel, p. 49.
9.Dugmore CR, Rock WP (2003). The progression of tooth erosion in a cohort of adolescents of mixed ethnicity. Int J Paediatr Dent Sep;13(5):295-303.
10.Eccles JD, Jenkins WG (1974). Dental erosion and diet. J Dent Jul;2(4):153-9
11.Edgar WM (1990). Saliva and dental health. Clinical implications of saliva: report of a consensus meeting. Br Dent J 169:96-8.
12.Edgar WM (1992). Saliva: its secretion, composition and functions. Br Dent J 172:305-12.
13.Edwards M, Ashwood RA, Littlewood SJ, Brocklebank LM, Fung DE (1998). A wideofluoroscopic comparison of straw and cup drinking: the potential influence on dental erosion. Br Dent J 185:244-249.
14.Eisenburger M, Addy M (2001). Evaluation of pH and erosion time on demineralisation. Clin Oral Investig Jun;5(2):108-11.
15.Erickson PR, Deanna LA, Darcy JR (2001). Soft drinks: hard on teeth. Northwest Dentistry 80:15–19.
16.Featherstone JD, Mayer I, Driessens FC, Verbeeck RM, Heijligers HJ (1983). Synthetic apatites containing Na, Mg, and CO3 and their comparison with tooth enamel mineral. Calcif Tissue Int 35(2):169-71.
17.Featherstone JD, Lussi A (2006).Understanding the chemistry of dental erosion. Monogr Oral Sci 20:66-76.
18.Fejerskov O, Stephen KW, Richards A, Speirs R (1987). Combined effect of systemic and topical fluoride treatments on human deciduous teeth--case studies. Caries Res 21(5):452-9.
19.Feldman M, Barnett C (1995). Relationships between the acidity and osmolality of popular beverages and reported postprandial heartburn. Gastroenterology Jan;108(1):125-31.
20.Ganss C, Schlechtriemen M, Klimek J (1999). Dental erosions in subjects living on a raw food diet. Caries Res 33:74-80.
21.Grant DA, Stern IB, Listgarten MA, editors (1988). Saliva. In: Periodontics. 6th ed. St Louis: CV Mosby p.135-46.
22.Grenby TH (1996). Lessening dental erosive potential by product modification. Eur J Oral Sci Apr;104:221-8.
23.Grobler SR, Jenkins GN, Kotze D (1985). The effects of the composition and method of drinking of soft drinks on plaque pH. British Dental Journal 158:293–7.
24.Gudmundsson K, Kristleifsson G, Theodors A, Holbrook WP (1995).Tooth erosion, gastroesophageal reflux, and salivary buffer capacity.Oral Surg Oral Med Oral Pathol Oral Radiol Endod Feb;79(2):185-9.
25.Hannig M (1999). Ultrastructural investigation of pellicle morphogenesis at two different intraoral sites during a 24-h period. Clin Oral Invest 3:88–95
26.Hannig C, Hannig M, Attin T (2005). Enzymes in the acquired enamel pellicle. Eur J Oral Sci 113:2–13
27.Harding AM, Satanovsky Y, Simmelink JW (1996). Thickness of human primary incisor enamel. Journal of Dental Research 75:196.
28.Harnack L, Stang J, Story M (1999). Soft drink consumption among US children and adolescents: nutritional consequences. Journal of American Dietary Association 99:436–41.
29.Hughes JA, West NX, Parker DM, Newcombe RG, Addy M (1999). Development and evaluation of a low erosive blackcurrant juice drink in vitro and in situ. 1. Comparison with orange juice. J Dent Jul;27(5):345-50.
30.Hughes JA, Jandt KD, Baker N, Parker D, Newcombe RG, Eisenburger M, Addy M (2002). Further modification to soft drinks to minimise erosion. A study in situ. Caries Res Jan-Feb;36(1):70-4.
31.Humphrey SP and Williamson RT (2001). A review of saliva: Normal composition, flow, and function. J Prosthet Dent 85:162-9.
32.Imfeld T (1996). Prevention of progression of dental erosion by professional and individual prophylactic measures. Eur J Oral Sci Apr;104:215-20.
33.Jaeggi T, Lussi A (1999). Toothbrush abrasion of erosively altered enamel after intraoral exposure to saliva: an in situ study. Caries Res Nov-Dec;33(6):455-61.
34.Järvinen VK, Rytömaa II, Heinonen OP (1991). Risk factors in dental erosion. J Dent Res Jun;70(6):942-7.
35.Johhansson AK, Sorvari R, Meurman JH (1998). In vitro effect of citric acid on deciduous and permanent enamel. Caries Research 32;310.
36.Johnson DA (1987). Regulation of salivary glands and their secretions by masticatory, nutritional and hormonal factors. In: Scribney LM, editor. The salivary system. Boca Raton, FL: CBC Press p.136-55.
37.Kerebel B, Daculsi G, Kerebel LM (1979). Ultrastructural studies of enamel crystallites. J Dent Res Mar;58(Spec Issue B):844-51.
38.Kuroiwa M, KodakaT (1993). Microstructural changes of human enamel surfaces by brushing with and without dentifrice containing abrasive. Caries Res 27:1-8.
39.Larsen MJ, Nyvad B (1999). Enamel Erosion by some soft drinks and orange juices relative o their pH, buffering effect and contents of calcium phosphate. Caries Research 33: 81–7.
40.Larsen MJ, Richards A (2002).Fluoride is unable to reduce dental erosion from soft drinks.Caries Res Jan-Feb;36(1):75-80.
41.Lendenmann U, Grogan J, Oppenheim FG (2000). Saliva and dental pellicle—a review. Adv Dent Res 14:22–28
42.Lussi A, Jaeggi T, Jaeggi-Schärer S (1995). Prediction of the erosive potential of some beverages. Caries Res 29:349–354
43.Mahoney E, Beattie J, Swain M, Kilpatrick N (2003). Preliminary in vitro assessment of erosive potential using the ultra-micro- indentation system. Caries Res 37:218–224
44.Mandel ID (1989). Impact of saliva on dental caries. Compend Suppl S476-81.
45.Mandel ID (1993). Salivary diagnosis: promises, promises. Ann NY Acad Sci 694:1-10.
46.Margolis HC, Moreno EC (1992). Kinetics of hydroxyapatite dis- solution in acetic, lactic and phosphoric acid solutions. Calcif Tissue Int 50: 137–143.
47.Margolis HC, Zhang YP, Lee CY, Kent RL jr, Moreno EC (1999). Kinetics of enamel demineralisation in vitro. J Dent Res 78: 1326–1335.
48.Meurman JH, ten Cate JM (1996). Pathogenesis and modifying factors of dental erosion. Eur J Oral Sci Apr;104:199-206.
49.Millward A, Shaw L, Smith AJ, Rippin JW, Harrington E (1994). The distribution and severity of tooth wear and the relationship between erosion and dietary constituents in a group of children. Int J Paediatr Dent. Sep;4(3):151-7.
50.Millward A, Shaw L, Smith A (1994). Dental erosion in four-year-old children from differing socioeconomic backgrounds. J Dent Child 61:263-266.
51.Nelson DG (1981). The influence of carbonate on the atomic structure and reactivity of hydroxyapatite. J Dent Res Aug;60 Spec No C:1621-9
52.O’Brien M (1994). Children’s dental health in the United Kingdom 1993. London: Office of Population Censuses and Surveys 1994. Her Majesty’s Stationary Office.
53.Odutuga AA, Prout RE (1974). Lipid analysis of human enamel and dentine. Arch Oral Biol Aug;19(8):729-31
54.Rees JS (2004). The role of drinks in tooth surface loss. Dent Update Jul-Aug;31(6):318-20, 322-4, 326.
55.Reussner GH, Coccodrilli G Jr, Thiessen R Jr (1975). Effects of phosphates in acid-containing beverages on tooth erosion.J Dent Res Mar-Apr;54(2):365-70.
56.Roth G, Calmes R, editors (1981). Salivary glands and saliva. In: Oral biology. St Louis: CV Mosby p.196-236.
57.Scheutzel P (1996). Etiology of dental erosion-intrinsic factors. Eur J Oral Sci 104(2Pt2):178-190.
58.Shaw L, Smith A (1994). Erosion in children: an increasing clinical problem? Dent Update Apr;21(3):103-6.
59.Sorvari R, Harri M (1989). Effect of sport-drink with and without fluoride and magnesium supplements on rat performance. Eur J Appl Physiol Occup Physiol 58(7):738-43.
60.Sorvari R, Rytomaa I (1991). Drinks and dental heath. Proceedings of Finnish Dental Society 87:621–31.
61.Tahmassebi JF, Duggal MS, Malik-Kotru G, Curzon ME (2006). Soft drinks and dental health: a review of the current literature. J Dent Jan;34(1):2-11.
62.Touyz LZ (1983).Fruit induced sensitivity at cervical margins. J Dent Assoc S Afr Mar;38(3):199-200.
63.Touyz LZ (1994). The acidity (pH) and buffering capacity of Canadian fruit juices and dental implications. Journal of the Canadian Dental Association 60:454–7.
64.Tuominen M, Tuominen R (1991).Dental erosion and associated factors among factory workers exposed to inorganic acid fumes.Proc Finn Dent Soc 87(3):359-64.
65.Weatherell JA, Robinson C, Ralph JP, Best JS (1984). Migration of fluoride in the mouth. Caries Research 18:348–53.
66.West NX, Hughes JA, Addy M (2000). Erosion of dentine and enamel in vitro by dietary acids: the effect of temperature, acid character, concentration and exposure time. Journal of Oral Rehabilitation 27:875–80.
67.West NX, Maxwell A, Hughes JA, Parker DM, Newcombe RG, Addy M (1998). A method to measure clinical erosion: the effect of orange juice consumption on erosion of enamel. J Dent May;26(4):329-35.
68.West NX, Hughes JA, Addy M (2001). The effect of pH on the erosion of dentine and enamel by dietary acids in vitro. J Oral Rehab 28: 860–864.
69.Wilson PR, Beynon AD (1989). Mineralization differences between human deciduous and permanent enamel measured by quantitative microradiography. Arch Oral Biol 34(2):85-8.
70.Young WG (1995). Diet and nutrition for oral health: advice for patients with tooth wear. Aust Dent Assoc News Bull July:8-10.
71.Young W, Khan F, Brandt R, Savage N, Razek AA, Huang Q (2001). Syndromes with salivary dysfunction predispose to tooth wear: Case reports of congenital dysfunction of major salivary glands, Prader-Willi, congenital rubella, and Sjögren's syndromes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod Jul;92(1):38-48.
72.Zero DT (1996). Etiology of dental erosion—extrinsic factors. European Journal of Oral Science 104:162–77.
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/44804-
dc.description.abstract目的
大多數的軟性飲料都是酸性的,飲用這些飲料可能會導致牙齒的酸蝕。本實驗的目的為利用體外實驗的方式來比較各種不同軟性飲料的酸蝕潛力。
材料與方法
本實驗使用四種台灣市面上可購得之軟性飲料。每種飲料皆會測量其初始pH值,可滴定酸度與鈣、磷酸根與氟離子含量來判斷酸蝕潛力。總計40片人類牙釉質樣本浸入各組飲料中各20分、1小時與3小時。之後使用雷射共焦掃描顯微鏡來觀測牙釉質酸蝕表面圖像與牙釉質喪失量。
結果
各組軟性飲料的pH值介於 2.42至3.46之間,而可滴定酸度則介於13.88至35.95 ml之0.1 M氫氧化鈉溶液。各飲料的離子含量中,鈣離子濃度介於5.69至75.94 ppm,磷酸根離子濃度介於2.88至 522.47 ppm,氟離子濃度介於0.10至 0.18 ppm之間。而浸入各種飲料3小時所造成之牙釉質喪失量介於7.28 至 34.07 μm之間。
結論
本實驗中所使用之軟性飲料皆會使人類恆齒牙釉質產生程度不一之酸蝕影響。其中含有高濃度鈣磷比例的飲料具有顯著較低的酸蝕潛力,而具有低pH值與高緩衝能力的飲料之酸蝕潛力則較高。而軟性飲料的酸蝕潛力需參考各種化學性質來判斷,包括酸的種類、pH值、可滴定酸度、鈣、磷酸根與氟離子濃度等等。
zh_TW
dc.description.abstractObjectives
Most soft drinks are acidic in nature and exposure to these drinks may result in enamel erosion. The aim of this study was to compare the erosive potential of different soft drinks in the laboratory.
Materials and methods
Four commercially available soft drinks in Taiwan were included. The erosive potential of each product was assessed by measuring its initial pH, titratable acidity, calcium, phosphate and fluoride content. Forty human permanent enamel samples were immersed in 100ml of the drinks for 20min, 1h and 3h. Erosive surface images and enamel loss in vitro were acquired after exposure by laser confocal scanning microscope.
Results
The initial pH of the soft drinks ranged from 2.42 to 3.46 with their titratable acidity ranging from 13.88 to 35.95 ml of 0.1 M NaOH. The ion concentration of the beverages ranged between 5.69 and 75.94 ppm for calcium, between 2.88 and 522.47 ppm for phosphate, and between 0.10 and 0.18 for fluoride. The amount of enamel loss following 3h immersion in the drinks ranges from 7.28 to 34.07 μm.

Conclusion
All of the soft drinks were found to be erosive. Drinks of high calcium and phosphate content may have a significant lower erosive potential. Drinks of low pH and high titratable acidity may have a higher erosive potential. The erosive potential should be predicted based on the type of acids, initial pH, titratable acidity and ion concentration.
en
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Previous issue date: 2010
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dc.description.tableofcontents口試委員會審定書……………………………………………………………i
中文摘要………………………………………………………………………ii
英文摘要………………………………………………………………………iv
目錄……………………………………………………………………………vi
圖目錄…………………………………………………………………………ix
表目錄…………………………………………………………………………x
第一章 文獻回顧 ……………………………………………………………1
1.1 酸蝕………………………………………………………………………1
1.1.1 定義……………………………………………………………………2
1.1.2 成因……………………………………………………………………2
1.1.3 診斷……………………………………………………………………3
1.2. 軟性飲料………………………………………………… ……………3
1.2.1 定義……………………………………………………………………3
1.2.2 歷史與現況……………………………………………………………3
1.2.3 軟性飲料與牙齒酸蝕…………………………………………………4
1.2.4 軟性飲料之酸蝕潛力…………………………………………………5
1.2.4.1 酸與pH值……………………………………………………………5
1.2.4.2 可滴定酸度…………………………………………………………7
1.2.4.3 鈣、磷酸根、氟離子濃度與飽和度………………………………7
1.2.5 軟性飲料與青少年健康………………………………………………8
1.3 牙釉質……………………………………………………………………9
1.3.1 牙釉質結構……………………………………………………………9
1.3.2 牙釉質酸蝕過程………………………………………………………10
1.4 實驗目的…………………………………………………………………11
第二章 實驗材料與方法…………………………………………………… 12
2.1 測量pH值…………………………………………………………………12
2.1.1 pH計……………………………………………………………………13
2.1.2 校正步驟與使用注意事項……………………………………………13
2.1.3 測量步驟………………………………………………………………14
2.2 測量可滴定酸度…………………………………………………………15
2.2.1 製備氫氧化鈉水溶液…………………………………………………15
2.2.2 滴定步驟………………………………………………………………16
2.3 測量鈣、磷酸根、氟離子濃度…………………………………………16
2.3.1 製備陽離子流洗液……………………………………………………17
2.3.2 製備陰離子流洗液……………………………………………………17
2.3.3 製備離子標準品………………………………………………………17
2.3.4 測量步驟與注意事項…………………………………………………18
2.4 測量牙釉質喪失量………………………………………………………18
2.4.1 製備實驗用牙釉質樣本………………………………………………18
2.4.1.1 樣本來源……………………………………………………………19
2.4.1.2 樣本製備……………………………………………………………19
2.4.1.3 樣本分組……………………………………………………………20
2.4.2 酸蝕過程………………………………………………………………21
2.4.3 雷射共焦掃描顯微鏡觀測……………………………………………22
2.4.3.1 雷射共焦掃描顯微鏡原理與特色…………………………………22
2.4.3.2 觀測牙釉質樣本表面步驟…………………………………………24
2.4.3.3 測量牙釉質喪失量…………………………………………………25
2.5 統計方法…………………………………………………………………26
第三章 實驗結果 ……………………………………………………………27
3.1各種飲料之pH值 …………………………………………………………27
3.2各種飲料之可滴定酸度 …………………………………………………27
3.3各種飲料之離子濃度 ……………………………………………………28
3.4雷射共焦顯微鏡影像 ……………………………………………………28
3.5牙釉質喪失高度 …………………………………………………………31
第四章 討論 …………………………………………………………………34
4.1 酸蝕潛力…………………………………………………………………34
4.1.1 pH值與酸的種類 ……………………………………………………34
4.1.2 可滴定酸度……………………………………………………………36
4.1.3 鈣與磷酸根離子濃度與飽和度………………………………………38
4.2 顯微鏡影像與牙釉質喪失量……………………………………………40
4.3 儀器………………………………………………………………………42
4.4 體外實驗vs.體內實驗 …………………………………………………45
4.4.1 唾液……………………………………………………………………45
4.4.2 後天性薄膜……………………………………………………………47
4.5 個體差異…………………………………………………………………48
4.5.1 唾液……………………………………………………………………48
4.5.2 後天性薄膜……………………………………………………………49
4.5.3 乳恆牙差異……………………………………………………………50
4.5.4 行為差異………………………………………………………………51
4.6 飲用建議 ………………………………………………………………52
第五章 結論 …………………………………………………………………54
第六章 實驗未來展望 ………………………………………………………55
參考文獻………………………………………………………………………56
圖一 本實驗所使用之四種軟性飲料 ………………………………………62
圖二 pH計 ……………………………………………………………………62
圖三 超音波震盪器 …………………………………………………………63
圖四 電磁攪拌器 ……………………………………………………………63
圖五 離子層析儀 ……………………………………………………………64
圖六 硬組織研磨機 …………………………………………………………64
圖七 製備好待用之牙釉質塊樣本 …………………………………………65
圖八 牙釉質樣本示意圖 ……………………………………………………65
圖九 雷射共焦顯微鏡 ………………………………………………………66
圖十 經可口可樂酸蝕後之牙釉質樣本與彩色高度顯示圖(200X) ………67
圖十一 經黑松沙士酸蝕後之牙釉質樣本與彩色高度顯示圖(200X)……67
圖十二 經可爾必思酸蝕後之牙釉質樣本與彩色高度顯示圖(200X)……68
圖十三 經C.C.Lemon酸蝕後之牙釉質樣本與彩色高度顯示圖(200X)……68
圖十四 經可口可樂酸蝕過之牙釉質表面(1000X) ………………………69
圖十五 經黑松沙士酸蝕過之牙釉質表面(1000X) ………………………70
圖十六 經可爾必思酸蝕過之牙釉質表面(1000X) ………………………71
圖十七 經C.C. lemon酸蝕過之牙釉質表面(1000X) ……………………72
dc.language.isozh-TW
dc.title市售軟性飲料對於人類恆齒牙釉質表面之酸蝕影響:體外實驗zh_TW
dc.titleErosive Effect of Soft Drinks on Permanent Human Enamel Surface: an in Vitro Studyen
dc.typeThesis
dc.date.schoolyear98-2
dc.description.degree碩士
dc.contributor.oralexamcommittee廖運炫,林弘萍
dc.subject.keyword牙齒酸蝕,軟性飲料,牙釉質,雷射共焦掃描顯微鏡,zh_TW
dc.subject.keywordDental erosion,Soft drinks,Enamel,Laser confocal scanning microscope,en
dc.relation.page77
dc.rights.note有償授權
dc.date.accepted2010-06-25
dc.contributor.author-college牙醫專業學院zh_TW
dc.contributor.author-dept臨床牙醫學研究所zh_TW
顯示於系所單位:臨床牙醫學研究所

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