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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 季瑋珠(Wei-Chu Chie) | |
| dc.contributor.author | I-Chun Chen | en |
| dc.contributor.author | 陳逸群 | zh_TW |
| dc.date.accessioned | 2021-06-15T02:28:53Z | - |
| dc.date.available | 2009-09-16 | |
| dc.date.copyright | 2009-09-16 | |
| dc.date.issued | 2009 | |
| dc.date.submitted | 2009-08-17 | |
| dc.identifier.citation | 1.Anja, D.-M., Josef, H., Daniel, M., Thilo, B., Edi, B., &
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Treatment of addictive behaviors in liver transplant patients. Liver Transpl, 13(11 Suppl 2), S79-82. 51. WHO. (2007). WHO EXPERT COMMITTEE ON PROBLEMS RELATED TO ALCOHOL CONSUMPTION: World Health Organization. 52. Wurst, F. M., Dursteler-MacFarland, K. M., Auwaerter, V., Ergovic, S., Thon, N., Yegles, M., et al. (2008). Assessment of alcohol use among methadone maintenance patients by direct ethanol metabolites and self-reports. Alcohol Clin Exp Res, 32(9), 1552-1557. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/43795 | - |
| dc.description.abstract | 目的：探究美沙冬維持療法患者酒精使用問題的盛行率及預測因子，並探討美沙冬維持療法患者退出治療的預測因子；酒精使用問題分為「過量及有害飲酒」與「酒精濫用及酒精依賴」兩個層次說明。
方法： 本研究為前瞻性追蹤研究，研究對象為行政院衛生署桃園療養院、行政院衛生署豐原醫院兩家醫院中438位持續美沙冬維持療法六個月以上的患者，在初診時收集每位患者的人口學及臨床特徵，在治療期間收集治療相關變項，「過量及有害飲酒」與「酒精濫用及酒精依賴」之測量採用中文版酒精使用問題診斷量表及呼氣酒精濃度。 結果：美沙冬維持療法患者之過量飲酒及有害飲酒盛行率為31.4%，酒精濫用及酒精依賴盛行率為12.0%。美沙冬維持療法患者之過量飲酒及有害飲酒的保護因子有服藥出席率大於等於90%（OR=0.54，95%CI=0.30-0.97）、年齡大於35歲（OR=0.48，95%CI=0.27-0.86），原本有酒精使用（OR=5.30，95%CI=2.87-9.76）為危險因子。美沙冬維持療法患者退出治療的預測因子為美沙冬劑量小於60毫克(Wald test p-value<0.001)、未接受公費補助(Wald test p-value<0.001)。 結論：美沙冬維持療法患者的「過量及有害飲酒」高盛行率強調了酒精使用問題篩檢及介入是有需要的；越年輕、 遵醫囑性差、原本有酒精使用的美沙冬維持療法患者須接受「過量及有害飲酒」的篩檢。 | zh_TW |
| dc.description.abstract | OBJECTIVE: To examine the prevalence rate and predictors of alcohol use problem, as well as predictors of dropout among patients undergoing methadone maintenance treatment (MMT). Alcohol use problem is defined as two levels separately, level one is excessive and hazardous drinking, level two is alcohol abuse and dependence. METHODS: This is a prospective follow-up study. Study population includes 438 patients retaining more than 6 months in MMT from the Fong-Yuan Hospital and Tau-Yuan Psychiatric Center. Demographic and clinical characteristics were collected for each patient at the beginning, and treatment-related variables were collected during treatment process. Excessive drinking and hazardous drinking, alcohol abuse and dependence were measured by Chinese Version Alcohol Use Disorders Identification Test (Chinese Version AUDIT) and breath alcohol concentration. RESULT: The prevalence rate of excessive drinking and hazardous drinking among MMT patients is 31.4%, and the prevalence rate of alcohol abuse and dependence is 12.0%. The predictors of excessive and hazardous drinking among MMT patients include attendance rate more than 90%（OR=0.54，95%CI=0.30-0.97）, age older than 35 years old（OR=0.48，95%CI=0.27-0.86）,and alcohol use at intake（OR=5.30，95%CI=2.87-9.76） is a risk factor. The predictors of dropout among MMT patients include methadone dose less than 60 mg (Wald test p-value<0.001), without governmental fund (Wald test p-value<0.001).
CONCLUSION：The high prevalence rate of excessive and hazardous drinking among MMT patients underscores the needful screening and intervention for alcohol use problem .Those patients who are younger and have poor adherence, alcohol use at intake should be screened for excessive and hazardous drinking. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T02:28:53Z (GMT). No. of bitstreams: 1 ntu-98-P96846005-1.pdf: 1028116 bytes, checksum: ead4ad3d2aca092783cf74a3ada0bf00 (MD5) Previous issue date: 2009 | en |
| dc.description.tableofcontents | 口試委員會審定書 ii
中文摘要 iii 英文摘要 iv 第一章 研究背景 1 第一節 從「減害」模式來看鴉片類物質成癮者的酒精使用 1 第二章 文獻探討 4 第一節 關於酒精使用問題測量之過去研究 4 第二節 維持美沙冬維持療法治療時間相關因子的過去研究 9 第三節 美沙冬維持療法是否會改變酒精使用的過去研究 12 第四節 美沙冬維持療法者酒精使用的預測因子 16 第五節 服藥出席率的預測因子 18 第六節 美沙冬維持療法服藥出席率與過量飲酒及有害飲酒、酒精濫用及酒精依賴的過去研究 18 第七節 美沙冬的劑量對過量飲酒及有害飲酒、酒精濫用及酒精依賴的影響之過去研究 19 第三章 研究目的及假設 20 第一節 研究目的 20 第二節 研究假設 21 第四章 研究方法 23 第一節 研究對象 23 第二節 統計方法 31 第五章 結果 33 第一節 持續美沙冬維持療法的時間之描述性資料與相關預測因子 33 第二節 持續六個月以上美沙冬維持療法者之初診時人口學資料、預測因子 38 第三節 持續六個月以上美沙冬維持療法者之過量飲酒及有害飲酒盛行率、酒精濫用及酒精依賴盛行率 40 第四節 各項預測因子與「過量飲酒及有害飲酒」、「酒精濫用及酒精依賴」的單變項分析 40 第五節 檢定次要預測因子與主要預測因子（美沙冬劑量、服藥出席率）的相關性 42 第六節 持續六個月以上美沙冬維持療法者之過量及有害飲酒、酒精濫用及酒精依賴的多變項分析 44 第六章 討論 51 第一節 回顧研究目的與整體結果概述 51 第二節 對於個別結果的說明與推論 51 第三節 整體研究結果之臨牀應用 54 第四節 本研究的優點 55 第五節 本研究的限制 56 第六節 結論 57 參考文獻 58 表格目錄： Table 2-1 Measurement and Definition of Alcohol Use Problem 6 Table 2-2 Literature Review on Predictors of Retention Time of Methadone Maintenance Treatment 11 Table 2-3 Literature Review on Change of Alcohol Use after Methadone Maintenance Treatment 14 Table 2-4 Literature Review on Predictors of Alcohol Use in Methadone Maintenance Treatment Patients 17 Table 4-1 受試者選擇標準 27 Table 5-1 Crude and Adjusted Hazards Ratios of Drop out from Methadone Maintenance Treatment (MMT) in Patients of Fong-Yuan Hospital (n=518) 35 Table 5-2 Baseline characteristics data in 438 patients with more the 6 months methadone maintenance treatment (MMT) 39 Table 5-3 Baseline Characteristics between the Groups in Aspects of Methadone Dose and Attendance Rate 43 Table 5-4 Crude and Adjusted Odds Ratios of Hazardous Drinking in the Study Subjects(n=274) 46 Table 5-5 Crude and Adjusted Odds Ratios of alcohol abuse and dependence in the Study Subjects(n=274) 48 Table 5-6 Hazardous Drinking in Study Subjects between Different cutout Point of Attendance Rate (n=86) 50 圖目錄： 圖 3-1 主要自變項、依變項及次要自變項示意圖 22 圖 4-1 收案及追蹤時間 28 圖 4-2 收案及追蹤流程 29 圖 4-3 中文版酒精使用問題診斷量表 30 Figure 5-1 Survival-Curve Plot for Retaining in Methadone Maintenance Treatment in Patients of Fong-Yuan Hospital (n=518) 34 Fiqure 5-2 Survival-Curve Plot for the Retaining in Methadone Maintenance Treatment in Patients of Fong-Yuan Hospital in Aspect of Alcohol at Intake (n=518) 34 | |
| dc.language.iso | zh-TW | |
| dc.subject | 過量飲酒 | zh_TW |
| dc.subject | 出席率 | zh_TW |
| dc.subject | 美沙冬維持療法 | zh_TW |
| dc.subject | 有害飲酒 | zh_TW |
| dc.subject | excessive drinking | en |
| dc.subject | attendance rate | en |
| dc.subject | methadone maintenance treatment (MMT) | en |
| dc.subject | hazardous drinking | en |
| dc.title | 美沙冬維持療法患者之酒精使用問題 | zh_TW |
| dc.title | Alcohol Use Problem among Patients in
Methadone Maintenance Treatment Program | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 97-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 胡海國(Hai-Go Hwu) | |
| dc.contributor.oralexamcommittee | 劉仁沛(Jen-Pei Liu),程蘊菁(Yen-Ching Karen Chen),陳喬琪(Chiao-Chicy Chen) | |
| dc.subject.keyword | 過量飲酒,有害飲酒,美沙冬維持療法,出席率, | zh_TW |
| dc.subject.keyword | excessive drinking,hazardous drinking,methadone maintenance treatment (MMT),attendance rate, | en |
| dc.relation.page | 62 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2009-08-17 | |
| dc.contributor.author-college | 公共衛生學院 | zh_TW |
| dc.contributor.author-dept | 預防醫學研究所 | zh_TW |
| 顯示於系所單位： | 流行病學與預防醫學研究所 | |
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