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http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/42913完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 趙福杉(Fu-Shan Jaw) | |
| dc.contributor.author | Wei-Jie Weng | en |
| dc.contributor.author | 翁偉傑 | zh_TW |
| dc.date.accessioned | 2021-06-15T01:28:36Z | - |
| dc.date.available | 2009-07-29 | |
| dc.date.copyright | 2009-07-29 | |
| dc.date.issued | 2009 | |
| dc.date.submitted | 2009-07-21 | |
| dc.identifier.citation | [1] Welgampola MS, Colebatch JG, “Characteristic and clinical applications of vestibular-evoked myogenic potentials,” Neurology. 2005 May 24;64(10):1682-8. Review.
[2] http://upload.wikimedia.org/wikipedia/commons/c/cd/VanGogh-starry_ night.jpg [3] http://en.wikipedia.org/wiki/Vincent_van_Gogh [4] Susan J. Herman, “Vestibular rehabilitation,” 3rd edition, 2006. [5] http://en.wikipedia.org/wiki/File:Bigotolith.jpg [6] Colebatch JG, Halmagyi GM, Skuse NF., “Myogenic potentials generated by a click-evoked vestibulocollic reflex,” J Neurol Neurosurg Psychiatry 1994;57:190-7. [7] Rosengren SM, Todd NP, Colebatch JG., “Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound,” Clin Neurophysiol 2005;116:1938-48. [8] Todd NP, Rosengren SM, Aw ST, Colebatch JG., “Ocular vestibular evoked myogenic potentials (OVEMPs) produced by air- and bone-conducted sound,” Clin Neurophysiol 2007;118:381-90. [9] http://openlearn.open.ac.uk/mod/resource/view.php?id=263158 [10] de Burlet HM., ”Zur Innervation der Macula sacculi bei Säugetieren,” Anat Anzeig 1924;58:26–32. [11] Moffat AJM, Capranica RR., “Auditory sensitivity of the saccule in the American toad (Bufo americanus),” J Comp Physiol 1976;105:1–8. [12] Lowenstein O, Roberts TD., “The localization and analysis of the responses to vibration from the isolated elasmobranch labyrinth; a contribution to the problem of the evolution of hearing in vertebrates,” J Physiol 1951;114:471–489. [13] Todd NP, Rosengren SM, Colebatch JG., “A utricular origin of frequency tuning to low-frequency vibration in the human vestibular system?' Neurosci Lett. 2009 Feb 27;451(3):175-80. Epub 2009 Jan 6. [14] http://en.wikipedia.org/wiki/File:Sternocleidomastoideus.png [15] Welgampola MS, “Evoked potential testing in neuro-otology,” Current Opinion in Neurology, 2008, 21:29-35 [16] Chihara Y, Iwasaki S, Ushio M, Murofushi T., “Vestibular-evoked extraocular potentials by air-conducted sound: another clinical test for vestibular function,” Clin Neurophysiol. 2007;118:2745-51. [17] Wang SJ, Weng WJ, Jaw FS, Young YH, “ Ocular / cervical vestibular evoked myogenic potentials:air conducted sound versus bone conducted vibration stimulation modes.” Ear Hear, 2009 (submitted). [18] Curthoys IS, Kim J, McPhedran SK, Camp AJ., 'Bone conducted vibration selectively activates irregular primary otolithic vestibular neurons in the guinea pig,” Exp Brain Res 2006;175:256-67. [19] Brantberg K, Löfqvist L, Westin M, Tribukait A., 'Skull tap induced vestibular evoked myogenic potentials: An ipsilateral vibration response and a bilateral head acceleration response?” Clin Neurophysiol. 2008;119:2363-9. [20] Iwasaki S, Smulders YE, Burgess AM, McGarvie LA, MacDougall HG, Halmagyi GM, et al., “Ocular vestibular evoked myogenic potentials to bone conducted vibration of the midline forehead at Fz in healthy subjects,” Clin Neurophysiol 2008;119:2135-47. [21] J. G. Webster, “Medical instrumentation application and design,” 1998. [22] Todd NP, Rosengren SM, Colebatch JG., “Tuning and sensitivity of the human vestibular system to low-frequency vibration,” Neurosci Lett. 2008 Oct 17;444(1):36-41. Epub 2008 Aug 8. [23] Rosengren SM, Jombik P, Halmagyi GM, Colebatch JG., “Galvanic ocular vestibular evoked myogenic potentials provide new insight into vestibulo-ocular reflexes and unilateral vestibular loss,” Clin Neurophysiol. 2009 Mar;120(3):569-80. Epub 2009 Mar 9. [24] http://xianying.myweb.hinet.net/i22.html [25] U. Tietze, Ch. Schenk, “Electronic circuits design and application,” 1990. [26] Iwasaki S, Smulders YE, Burgess AM, McGarvie LA, Macdougall HG, Halmagyi GM, Curthoys IS., “Ocular vestibular evoked myogenic potentials to bone conducted vibration of the midline forehead at Fz in healthy subjects,” Clin Neurophysiol. 2008 Sep;119(9):2135-47. Epub 2008 Jul 17. [27] Jaw FS, Yen CT, Tsao HW, Yu HJ, “A modified “triangular pulse”stimulator for C-fibers stimulation,” J Neurosci Methods. 1991 Apr;37(2):169-72. [28] 蔡曜至, ”電生理信號量測系統的開發-從基礎生物醫學記錄到臨床應用,” 國立台灣大學醫學工程學研究所碩士論文, 2003. [29] 陳弘杰, “可攜式加速規記錄器,” 國立台灣大學醫學工程學研究所碩士論文, 2002. [30] 梁育榕, “控制尿失禁之雙通道電刺激器,” 國立台灣大學醫學工程學研究所碩士論文, 2006. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/42913 | - |
| dc.description.abstract | 前庭之耳石器官是前庭系統中負責人體之平衡感覺的器官之一，可接受頭部之線性加速度以及傾斜度的刺激，使人可以感受到頭部的空間位置與位置的改變，並作出適當反應。近年來因前庭誘發肌性電位理論的提出，使深藏於內耳深處的耳石器官得以透過表面肌電位的量測，利用非侵入式的方法判定其功能之好壞，進而提供醫師客觀評估耳石器官功能與病變的依據。
本研究之目的即為整合能誘發前庭反應的刺激模式－聲音刺激、機械性刺激(含頭部加速度記錄)、以及電刺激，並根據前庭誘發肌性電位之電位大小及頻譜，研製一具有最佳化規格之放大濾波的四通道記錄系統，以改善市售儀器之功能不敷使用及不易整合的缺點。整套系統以個人電腦為使用平台，透過A/D卡及LabVIEW所開發而成的虛擬儀錶程式連結成一具使用彈性、低價格、低功率消耗並能搭配實驗及研究需求而快速開發的一套刺激記錄系統，作為將來臨床實驗之設備。 | zh_TW |
| dc.description.abstract | The human otolith organs in the inner ear are peripheral sensory apparatuses responsible for the perception of head and body orientation. They respond to both linear head motion and static tilt with respect to gravitational axis. In recent years, the development of vestibular-evoked myogenic potential (VEMP) theory allows clinicians to evaluate the function of otolith organs and otolith-related disorders objectively and non-invasively by means of the recording of myogenic potential elicited by proper stimulation of these organs.
The aim of this study is to integrate three kinds of stimulation modes－air conducted sound, bone conducted vibration(with the recording of head acceleration), and galvanic stimulation－and a four-channel recording system optimized for VEMP recording, in replacement of commercial machines inadequate for their function and system integration, was developed. The system is implemented on a personal computer platform through the use of an A/D data acquisition card and a LabVIEW GUI-based virtual instrument. The low-cost, low-power consumption stimulating and recording system is flexible and suitable for future clinical experiments. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-15T01:28:36Z (GMT). No. of bitstreams: 1 ntu-98-R97548007-1.pdf: 2968800 bytes, checksum: d848b6c1b0ab2c889edbefd325756763 (MD5) Previous issue date: 2009 | en |
| dc.description.tableofcontents | 目錄………………………………………………………………………I
圖表目錄………………………………………………………………III 中文摘要………………………………………………………………VI 英文摘要………………………………………………………………VII 第一章 緒論……………………………………………………………1 1.1 研究背景………………………………………………………1 1.2 研究目的………………………………………………………5 第二章 系統架構………………………………………………………7 2.1 VEMP記錄系統之放大率波選擇………………………………7 2.2 頭部加速度記錄系統之放大濾波選擇………………………8 2.3 聲音刺激之系統配置…………………………………………8 2.4 機械性刺激之系統配置………………………………………8 2.5 定電流刺激器之系統配置……………………………………9 2.6 資料擷取及系統控制…………………………………………10 第三章 結果……………………………………………………………16 3.1 VEMP記錄系統…………………………………………………16 3.1.1 前級放大器電路…………………………………………16 3.1.2 後級放大濾波電路………………………………………17 3.1.3 後級放大濾波電路之頻率響應…………………………18 3.1.4 電極配置…………………………………………………18 3.1.5 系統完成圖及波形測試…………………………………18 3.1.6 討論………………………………………………………19 3.2 頭部加速度記錄系統…………………………………………28 3.2.1 加速規的選擇……………………………………………28 3.2.2 放大濾波電路……………………………………………28 3.2.3 放大濾波電路之頻率響應………………………………30 3.2.4 機械性刺激及加速規之量測位置………………………30 3.2.5 系統完成圖及波形測試…………………………………30 3.2.6 討論………………………………………………………31 3.3 定電流刺激器…………………………………………………36 3.3.1 脈波產生器………………………………………………36 3.3.2 電氣隔離電路……………………………………………36 3.3.3 定電壓/定電流源………………………………………37 3.3.4 討論………………………………………………………38 第四章 結論與討論……………………………………………………44 參考文獻………………………………………………………………46 | |
| dc.language.iso | zh-TW | |
| dc.subject | 前庭誘發肌性電位 | zh_TW |
| dc.subject | 平衡 | zh_TW |
| dc.subject | 前庭覺刺激 | zh_TW |
| dc.subject | 耳石器官 | zh_TW |
| dc.subject | 前庭 | zh_TW |
| dc.subject | vestibular stimuli | en |
| dc.subject | balance | en |
| dc.subject | vestibular-evoked myogenic potential (VEMP) | en |
| dc.subject | otolith organ | en |
| dc.subject | vestibule | en |
| dc.title | 前庭誘發肌性電位刺激及記錄系統之整合及研製 | zh_TW |
| dc.title | Vestibular-evoked Myogenic Potential (VEMP) Stimulating and Recording System | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 97-2 | |
| dc.description.degree | 碩士 | |
| dc.contributor.coadvisor | 王守仁(Shou-Jen Wang) | |
| dc.contributor.oralexamcommittee | 郭德盛,謝建興 | |
| dc.subject.keyword | 前庭,耳石器官,前庭誘發肌性電位,平衡,前庭覺刺激, | zh_TW |
| dc.subject.keyword | vestibule,otolith organ,vestibular-evoked myogenic potential (VEMP),balance,vestibular stimuli, | en |
| dc.relation.page | 49 | |
| dc.rights.note | 有償授權 | |
| dc.date.accepted | 2009-07-22 | |
| dc.contributor.author-college | 工學院 | zh_TW |
| dc.contributor.author-dept | 醫學工程學研究所 | zh_TW |
| 顯示於系所單位： | 醫學工程學研究所 | |
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