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標題: | 傢俱業者呼出氣體中揮發性有機物之分析研究 Volatile Organic Compounds in Exhaled Air of Furniture Sales Department Clerks |
作者: | Yun-Chen Wei 魏筠蓁 |
指導教授: | 馬一中(Yee-Chung Ma) |
關鍵字: | 呼出氣體,揮發性有機物,傢俱業者,甲醛,肺泡體積含量梯度, exhaled air,volatile organic compounds,furniture sales department clerk,formaldehyde,alveolar gradient, |
出版年 : | 2005 |
學位: | 碩士 |
摘要: | 本研究針對傢俱業者採樣分析其呼出氣體之揮發性有機物,觀察揮發性有機物之變異及其受職業暴露影響。除了偵測呼出氣體中揮發性有機物,環境空氣中甲醛及揮發性有機物亦一併量測,再佐以自填式問卷進行連結探討。
研究設計為橫斷研究,選取台北市文昌街、南昌路及台一線新莊路段之傢俱賣場業者為研究對象。傢俱業者細分為一般傢俱業者及系統傢俱業者,並同時收集對照組做組別間差異比較,對照組是選取台北市中小學教職員工,共有一般傢俱業者29人,系統傢俱業者20人,對照組25人。呼出氣體中揮發性有機物以熱脫附配合低溫濃縮捕集以及氣相層析質譜儀進行分析,搭配現有的標準圖譜資料庫進行定性,並採用半定量方式來定量,計算各化合物之肺泡體積含量梯度來表示各化合物在肺泡中的相對量大小。 本研究共分析了60種以上之呼出氣體中揮發性有機物,種類包括直鏈及支鏈碳氫化合物、酮類、呋喃類、芳香族、硫化物、含氯化合物、含氮化合物及其他類等。實驗結果使用SPSS13版軟體進行統計分析,發現有10種揮發性有機物的肺泡氣體含量濃度梯度在三組間的非抽菸受試者達統計上顯著差異(P<0.05),環境空氣中包含ethylbenzene、1,3-dimethyl-benzene在內共有25種化合物之相對量達統計顯著差異(P<0.05),三組間空氣中甲醛濃度亦達統計上顯著差異(P<0.01)。 沒有抽菸習慣的受試者其呼出氣體中pentane的肺泡體積含量梯度在傢俱組與對照組間達統計上顯著差異。經統計後發現pentane的肺泡體積含量梯度與環境空氣中的ethylbenzene、1,3-dimethyl-benzene的相對量亦達顯著差異,故環境空氣中ethylbenzene、1,3-dimethyl-benzene有可能會影響呼出氣體中pentane。 This study was aimed to analyze volatile organic compounds (VOCs) in exhaled air of furniture sales department clerks, and to observe the variation of VOCs from occupational exposure. In addition to exhaled air VOCs, formaldehyde and VOCs in the environmental air were also measured, and there relationship together with items in the questionnaire were discussed. The study design was a cross-section study. The furniture sales department clerks were divided into common furniture sales department clerks and systematic furniture sales department clerks. Seventy-four volunteers were participated in this study, including twenty-nine in ordinary furniture sales department、twenty in systematic furniture sales department and twenty-five in control. The VOCs in exhaled air was collected in a Tedlar bag and was analyzed using thermal desorption GC/MS. Each compound was identified based on the mass spectrum using Wiley 275 mass spectra library, and semi-quantitative analysis was used to measure the alveolar gradient of each compound. More than sixty compounds were detected, including alkanes, alkenes, ketones, furans, aromatics, sulfur-containing compounds, chlorine-containing compounds and nitrogen-containing compounds. Statistical analysis indicated that ten compounds in the exhaled air of non-smoking volunteers were significantly different among the three groups (p<0.05). Twenty-six compounds in the air, including ethylbenzene , 1,3-dimethyl-benzene and formaldehyde, were significantly different among the three groups (p<0.05). The alveolar gradient of pentane in non-smoking volunteers was significantly different between the furniture sales department clerks and the control volunteers, and was significantly different with the relative abundance of ethylbenzene and 1,3-dimethyl-benzene in air. Thus, exhaled air pentane abundance may be influenced by ethylbenzene and 1,3-dimethyl-benzene in air. |
URI: | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/35289 |
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顯示於系所單位: | 環境衛生研究所 |
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