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DC 欄位 | 值 | 語言 |
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dc.contributor.advisor | 陳右穎,趙福杉 | |
dc.contributor.author | Ching-Chih Lin | en |
dc.contributor.author | 林敬致 | zh_TW |
dc.date.accessioned | 2021-06-13T06:02:00Z | - |
dc.date.available | 2006-06-26 | |
dc.date.copyright | 2006-06-26 | |
dc.date.issued | 2006 | |
dc.date.submitted | 2006-06-21 | |
dc.identifier.citation | [1] 李玉春, “糖尿病疾病管理制度之基本理念-共同照護模式之應用”,國立陽明大學衛生福利研究所研究計畫, pp.1-5,民國89年。
[2] http://www.doh.gov.tw/statistic/index.htm,行政院衛生署。 [3] Jasmin Shah, Ebtisam Wilkins, “Electrochemical Biosensors for Detection of Biological Warfare Agents”, Electroanalysis, Vol 15, 2003, p157~167. [4] Turdean G. L., Thevenot D. R., Popescu I. C., Oniciu L., “Sensitive Detection of Organophosphorus Pesticides Using a Needle Type Amperometric Acetylcholinesterase-based Bioelectrode. Thiocholine Electrochemistry and Immobilised Enzyme Inhibition”, Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 17, 2002, p107~115. [5] E. M. Garrido, C. Delerue-Matos, J. L. F. C. Lima, A. M. O. Brett, “Electrochemical Methods in Pesticides Control”, Analytical Letters, Vol 37, 2004, p1755~1791. [6] J. M. Zen, H. H. Chung and A. S. Kumar,“Application of the chemical imaging sensor to electrophysiological measurement of a neural cell”, Sensor and Actuators B, Vol 125, 2000, p1633~1637. [7] Arun Kumar, Rajesh, Asha Chaubey, S. K. Grover, B. D. Malhotra, “Immobilization of Cholesterol Oxidase and Potassium Ferrycyanide on Sulfonate Ion-Doped Polypyrrole Film”, Journal of Applied Polymer Science, Vol 82, 2001, p3486~3491. [8] Wei-Yin Liao, Yuan-Gee Lee, Chun-Yueh Huang, Huan-Yu Lin, Yu-Ching Weng, Tse-Chuan Chou, “Telemetric electrochemical sensor”, Biosensor & Bioelectronics, 2004, p482~490. [9] 邱承美,陶金華,“儀器分析原理”, 1972, p408~521. [10] Frieder Scheller, Florian Schubert, “BIOSENSORS”, 1992, p10~34. [11] 林志達,“經濟型血糖感測器之製作及市售電極片之評估”, 中原大學醫學工程研究所, 碩士論文, 2002, p19~22. [12] M. Lambrechts and W. Sansen, “ Biosensors: microelectrochemical devices”, Institute of Physics Publishing Bristol, Philadelphia and New York,1992,pp.20~66. [13] A. E. G. CASS, “Biosensors A Practical Approach”, 1990, p19~45. [14] Qingshan Shan, Ying Liu, Gareth Prosser, David Brown, “Wireless Intelligent Sensor Networks for Refrigerated Vehicle”, IEEE 6th CAS Symp. On Emerging Technologies: Mobile and Wireless Comm., 2004, p525~528. [15] 黃志鴻, “以技術預測方法探討家庭自動化系統需求與發展之趨勢”, 交通大學科技管理研究所, 碩士論文, 2003, p48~53. [16] U. Tietz, Ch. Schenk, “Electronic Circuits”, 1990, p477~510. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/34299 | - |
dc.description.abstract | 本文在於發展出一可攜式生化感測器,目標是開發出體積小、重量輕、容易操作的多功能感測器。為了方便使用,感測器內建無線傳輸的功能,能讓使用者將量測的到數據方便傳回電腦。並以Visual Basic設計了一簡易電腦視窗接收介面,資料傳入資料庫後未來可作更深入的分析。感測器核心為單晶片微處理機,可程式化的特性讓感測器的應用更具彈性。
感測器目前設定應用為血糖之量測,電位差設定為300 mV,感測器並會自動偵測血糖是否已滴上電極表面,再以簡短的時間量測並顯示結果,以達到快速檢測的目的及人性化的操作。針對不同物質的量測需要有不同的感測電壓,然而本感測器可改變輸出的電位,其數位至類比轉換之電壓輸出經由韌體設定後,可由操作者決定輸出電壓之值,其最大輸出範圍在±1 V間,解析度達1 mV。 使用葡萄糖標準品及血糖酵素電極測試分析後,其量測到的電流反應與濃度的關係,呈現良好的線性關係,且與電化學實驗的大型分析儀比對的結果十分接近。此感測器的成品體積約為手掌大小,應有利於使用者之攜帶。 | zh_TW |
dc.description.abstract | This research is to develop a portable biochemical signal detector which should be lightweight, compact size, ease of use, and multiple functions. The built-in wireless function is for convenient. The measured data could efficiently send back to the database for further analysis. A user interface, developed under the Visual Basic, is developed for data collection. The kernel of the device is a programmable microcontroller. Such an architecture features with great flexibility.
For glucose measurement, the output potential must be set at 300 mV, and the device will automatically detect whether the glucose has been dropped on the electrodes to attain the goals of fast detection and user friendly. According to different applications, different potential should be apply to the sensing electrode. Furthermore, the output potential can be changed by the user after programming the microcontroller with adequate firmware. The output potential swing is ±1 V with 1 mV resolution. The results, obtained from electrodes with GOD( glucose oxidase ) on its surface and glucose solutions of standard concentrations show that the output current of this device can precisely represent the glucose concentration. While compared with a benchtop electrochemical analyzer, this device shows excellent linearity. The finished prototype is very compact, about the same size as a paw of a human being, and is suitable for portable use. | en |
dc.description.provenance | Made available in DSpace on 2021-06-13T06:02:00Z (GMT). No. of bitstreams: 1 ntu-95-R93548013-1.pdf: 1359552 bytes, checksum: 5a39afd39d570c4b8896c6de8889e2bf (MD5) Previous issue date: 2006 | en |
dc.description.tableofcontents | 致謝............................................................................................................I
圖目錄…………………………………………………………………...V 表目錄………………………………………………………………...VIII 中文摘要………………………………………………………………..IX 英文摘要………………………………………………………………...X 一、緒論………………………………………………………………1~13 1.1前言…………………………………..………………………1~2 1.2文獻回顧……………………………………..………………2~4 1.3理論基礎………………………………………..……………4~8 1.4研究動機與目的…………………………..…………………8~9 二、電路設計……………………………………..…………………14~36 2.1數位電路………………………………………..…………16~18 2.1.1外接式LCD面板、3×4矩陣式按鍵…………….………16 2.1.2燒錄以及UART傳輸介面模組………………..……….16 2.1.3無線傳輸電路………………………………………..16~17 2.1.4無線傳輸接收端電路……………………………………18 2.2 類比電路……………………………………….…………18~22 2.2.1DAC電路…………………………………...……………19 2.2.2可調增益式恆電位儀( potentiostat )…………..……19~21 2.2.3電源供應電路………………………………………..21~22 2.3韌體程式……………………………………………..……22~24 2.3.1生化感測儀程式設計…………………………..……21~22 2.3.2血糖量測程式設計………………………………………22 2.3.3接收端系統程式設計………………………..………23~24 2.4電腦介面......................................................................................24 2.4.1電腦端控制接收介面……………………………………24 三、結果………………………………………………………..……37~59 3.1電路系統測試………..……………………………………..37~41 3.1.1DAC輸出電壓測試……………………………………...38 3.1.2potentiostat之電流電壓專換測試…………………...38~39 3.1.3無線傳輸測試……………………………………………39 3.1.4LCD操作畫面……………………………………………40 3.1.5硬體規格……………………………………………..40~41 3.2實際試品量測………………………………………………41~42 3.2.1調配葡萄糖試品量測………………………………..41~42 3.2.2市售血糖標準品量測……………………………………42 3.3與商用儀器比較測試………………………………………42~43 3.3.1與CH Instruments比較測試………………………42~43 四、討論與結論……………………………………………………..60~61 參考文獻……………………………………………………………62~63 | |
dc.language.iso | zh-TW | |
dc.title | 無線可攜式生化感測儀 | zh_TW |
dc.title | Portable device for wireless biochemical measurement | en |
dc.type | Thesis | |
dc.date.schoolyear | 94-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 黃基礎,郭德盛,莊旻傑 | |
dc.subject.keyword | 生化感測器,電流式,電化學,無線傳輸,微控制器, | zh_TW |
dc.subject.keyword | biochemical sensor,amperometric,electrochemistry,wireless transmission,microcontroller, | en |
dc.relation.page | 63 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2006-06-22 | |
dc.contributor.author-college | 工學院 | zh_TW |
dc.contributor.author-dept | 醫學工程學研究所 | zh_TW |
顯示於系所單位: | 醫學工程學研究所 |
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