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Comparison the Methods of Blood Pressure Measurement and the Relationship between Blood Pressure and Microalbuminuria
|Publication Year :||2008|
Systemic blood pressure (SBP) level is a reference for diagnosis, treatment and clinical research in veterinary medicine and is used extensively in veterinary patients as a part of clinical assessment. Microalbuminuria is associated with increased risk of deterioration of hypertension. The aim of first part of the study was to evaluate the precision and efficiency of 2 indirect methods of systemic blood pressure measurement in conscious dogs in a clinical setting. Secondly, to evaluate use of semiquantitative test strips that was designed for human urine albumin in detection of canine microalbuminuria, and to evaluate association between microalbuminuria and systemic blood pressure (SBP) in dogs. The mean SBP values, measured by Doppler sphygmomanometry on 2 separate occasions, were 156 38.2 mmHg and 150 34.1 mmHg, respectively. Using oscillometry, the mean SBP values were 138 36.9 mm Hg and 133 33.5 mm Hg on 2 separate occasions. There were significant differences between the SBP readings for both methods on the same occasion (P<0.001). The coefficients of variance from 5 consecutive measurements in the same dog obtained by Doppler sphygmomanometry on the 2 separate occasions were 4.1 3.2% and 3.1 1.7%; that of the oscillometric method on the 2 separate occasions were 18.7 ± 11.3% and 17.2 ± 12.5%. The coefficients of variance of these 2 methods were statistically different on each occasion (P<0.001). Five consecutive SBP readings were obtained for each dog within 6 minutes on both occasions using Doppler sphygmomanometry. More than 15 minutes was required to complete 5 consecutive SBP readings by oscillometric sphygmomanometry for all dogs on each occasion. The results of this part of the study indicate that Doppler sphygmomanometry provides more efficient and precise measurements of the SBP level than oscillometric testing in conscious dogs in a clinical setting. The albumin-binding dye dipsticks for detecting canine albumin controls at the concentrations within assigned ranges (10 to 150 mg/L) were 100% concordance. However, canine globulin concentrations over 80 mg/L were detected false positively as presence of albumin. Off 100 clinically healthy dogs, 61 had negative result of microalbuminuria test, 39 were positive. Microalbuminuria was not associated with the blood pressure status (P = 0.71). Whereas microalbuminuria presented using urine albumin: creatinine ratio (UACR), 53 of 100 dogs did not have microalbuminuria, 45 were albuminuric, and 2 had proteinuria. The UACR was not associated with the blood pressure status (P = 0.65).
|Appears in Collections:||獸醫學系|
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